DK1401563T3 - Fremgangsmåde til fremstilling af mikro- og/eller nanopartikler - Google Patents

Fremgangsmåde til fremstilling af mikro- og/eller nanopartikler

Info

Publication number
DK1401563T3
DK1401563T3 DK01970064T DK01970064T DK1401563T3 DK 1401563 T3 DK1401563 T3 DK 1401563T3 DK 01970064 T DK01970064 T DK 01970064T DK 01970064 T DK01970064 T DK 01970064T DK 1401563 T3 DK1401563 T3 DK 1401563T3
Authority
DK
Denmark
Prior art keywords
carbon dioxide
solubilizing
supercritical
micronic
conditions
Prior art date
Application number
DK01970064T
Other languages
English (en)
Other versions
DK1401563T4 (da
Inventor
Ernesto Reverchon
Original Assignee
Micro & Nano Materials Sagl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4563123&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1401563(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Micro & Nano Materials Sagl filed Critical Micro & Nano Materials Sagl
Application granted granted Critical
Publication of DK1401563T3 publication Critical patent/DK1401563T3/da
Publication of DK1401563T4 publication Critical patent/DK1401563T4/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5192—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/02—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
    • B01J2/04—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops in a gaseous medium

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Optics & Photonics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK01970064.0T 2001-07-02 2001-09-27 Fremgangsmåde til fremstilling af mikro- og/eller nanopartikler DK1401563T4 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH12092001 2001-07-02
PCT/IB2001/001780 WO2003004142A1 (en) 2001-07-02 2001-09-27 Process for the production of micro and/or nano particles

Publications (2)

Publication Number Publication Date
DK1401563T3 true DK1401563T3 (da) 2006-08-14
DK1401563T4 DK1401563T4 (da) 2016-01-11

Family

ID=4563123

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01970064.0T DK1401563T4 (da) 2001-07-02 2001-09-27 Fremgangsmåde til fremstilling af mikro- og/eller nanopartikler

Country Status (8)

Country Link
US (1) US7276190B2 (da)
EP (1) EP1401563B2 (da)
AT (1) ATE323549T2 (da)
DE (1) DE60118983T3 (da)
DK (1) DK1401563T4 (da)
ES (1) ES2261469T5 (da)
PT (1) PT1401563E (da)
WO (1) WO2003004142A1 (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7767249B2 (en) * 2001-06-07 2010-08-03 Hewlett-Packard Development Company, L.P. Preparation of nanoparticles
WO2006035425A2 (en) * 2004-09-27 2006-04-06 Technion Research & Development Foundation Ltd. Spray method for producing semiconductor nanoparticles
WO2006062980A2 (en) * 2004-12-07 2006-06-15 Nektar Therapeutics Stable non-crystalline formulation comprising tiagabine
AU2006272438B2 (en) 2005-07-15 2011-08-04 Map Pharmaceuticals, Inc. Method of particle formation
US20070023035A1 (en) * 2005-07-29 2007-02-01 Kane Kevin M Method for processing drugs
US20080223136A1 (en) * 2005-08-04 2008-09-18 Tokyo Electron Limited Minute structure inspection device, inspection method, and inspection program
WO2007028421A1 (en) * 2005-09-09 2007-03-15 Universita' Degli Studi Di Padova Process for the production of nano-particles
US20070128291A1 (en) * 2005-12-07 2007-06-07 Tokie Jeffrey H Method and Apparatus for Forming Chromonic Nanoparticles
WO2008058054A2 (en) * 2006-11-06 2008-05-15 Novartis Ag Method for making parenteral pharmaceutical compositions in a unit dose container
CN100444943C (zh) * 2007-02-14 2008-12-24 浙江大学 水力空化增强超临界辅助雾化制备微粒的系统及其方法
RU2356609C1 (ru) * 2008-02-07 2009-05-27 Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт органической химии и технологии", ФГУП "ГосНИИОХТ" Способ получения нано- и микрочастиц водорастворимых веществ с использованием сверхкритического диоксида углерода
US9291139B2 (en) 2008-08-27 2016-03-22 Woodward, Inc. Dual action fuel injection nozzle
EP2181604A1 (en) * 2008-11-04 2010-05-05 Feyecon Development & Implementation B.V. Dispersion structuring agent
ES2342140B1 (es) * 2008-12-30 2011-05-17 Consejo Superior Investigacion Procedimiento para la obtencion de micro- o nanoparticulas solidas
CN103037961A (zh) * 2010-06-14 2013-04-10 X喷雾微粒公司 用于生产微粒的装置与方法
EP3302423B1 (en) 2015-06-04 2022-05-25 Crititech, Inc. Particle production system and particle collection device
BR112018069628A2 (pt) 2016-04-04 2019-02-12 Crititech, Inc. métodos para tratamento de tumor sólido
EP3615145B1 (en) 2017-06-09 2024-05-15 Crititech, Inc. Compositions for use in the treatment of epithelial cysts by intracystic injection of antineoplastic particles
WO2018231908A1 (en) 2017-06-14 2018-12-20 Crititech, Inc. Methods for treating lung disorders
KR20250057947A (ko) 2017-10-03 2025-04-29 크리티테크, 인크. 암의 치료를 위한 면역치료제의 전신 전달과 조합된 항신생물성 입자의 국소 전달
EP4190437A1 (en) * 2021-12-03 2023-06-07 SiTec PharmaBio SL Process and apparatus for the manufacture of solid microparticles

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4348422A (en) * 1978-02-13 1982-09-07 Studiengesellschaft Kohle M.B.H. Process for the direct decaffeination of aqueous coffee extract solutions
DE3937287A1 (de) * 1989-11-09 1991-05-16 Henkel Kgaa Verfahren und anlage zum abtrennen von fettsaeuremonoglycerid
US20020018815A1 (en) * 1992-03-06 2002-02-14 Sievers Robert E. Methods and apparatus for fine particle formation
GB9313642D0 (en) * 1993-07-01 1993-08-18 Glaxo Group Ltd Method and apparatus for the formation of particles
SI9400079B (sl) * 1994-02-15 2003-02-28 Dr. Weidner Eckhard, Dipl. Ing. Postopek in naprava za pridobivanje in frakcioniranje majhnih delcev iz raztopin nasičenih s plinom
EP0885038B1 (en) * 1996-03-01 2011-06-15 The University Of Kansas Methods and apparatus for particle precipitation and coating using near-critical and supercritical antisolvents
US5874029A (en) * 1996-10-09 1999-02-23 The University Of Kansas Methods for particle micronization and nanonization by recrystallization from organic solutions sprayed into a compressed antisolvent
US6221153B1 (en) * 1998-06-09 2001-04-24 Trevor Percival Castor Method for producing large crystals of complex molecules
SE9804000D0 (sv) * 1998-11-23 1998-11-23 Astra Ab New composition of matter
GB9828204D0 (en) * 1998-12-21 1999-02-17 Smithkline Beecham Plc Process
ES2170008B1 (es) 2000-08-25 2003-05-01 Soc Es Carburos Metalicos Sa Procedimiento para la precipitacion de particulas solidas finamente divididas.

Also Published As

Publication number Publication date
EP1401563B1 (en) 2006-04-19
EP1401563A1 (en) 2004-03-31
DE60118983T2 (de) 2007-01-11
US20040178529A1 (en) 2004-09-16
WO2003004142A1 (en) 2003-01-16
DK1401563T4 (da) 2016-01-11
PT1401563E (pt) 2006-08-31
DE60118983T3 (de) 2016-07-07
US7276190B2 (en) 2007-10-02
ES2261469T3 (es) 2006-11-16
ATE323549T2 (de) 2006-05-15
DE60118983D1 (de) 2006-05-24
ES2261469T5 (es) 2015-12-22
EP1401563B2 (en) 2015-09-16

Similar Documents

Publication Publication Date Title
DK1401563T3 (da) Fremgangsmåde til fremstilling af mikro- og/eller nanopartikler
Gañán-Calvo et al. A novel pneumatic technique to generate steady capillary microjets
Deepu et al. Dynamics of ultrasonic atomization of droplets
Sievers et al. Micronization of water-soluble or alcohol-soluble pharmaceuticals and model compounds with a low-temperature Bubble Dryer®
He et al. Precipitation of ephedrine by SEDS process using a specially designed prefilming atomizer
EP2338608A3 (en) Ultrasonic atomization method and apparatus
CN106463387A (zh) 采用微型·纳米气泡的清洗方法和清洗装置
Shaikeea et al. Insights into vapor-mediated interactions in a nanocolloidal droplet system: evaporation dynamics and affects on self-assembly topologies on macro-to microscales
JP7228166B2 (ja) 液滴粒子
Azhdarzadeh et al. An atomizer to generate monodisperse droplets from high vapor pressure liquids
Shi et al. Direct writing of suspended nanowires using coaxial electrohydrodynamic jet with double tip assistance
US6461546B1 (en) Apparatus for and method of producing monodisperse submicron polymer powders from solution
Das et al. Piperazine-activated diethanolamine formulation for post-combustion CO2 capture
Wang et al. High-aspect-ratio silica nozzle fabrication for nano-emitter electrospray applications
JP2007038124A (ja) 液体微粒子化ノズル及びそれを用いた装置
US8267914B1 (en) Method and apparatus for AC electrospray
Jayasinghe et al. Aerodynamically assisted jetting: a pressure driven approach for processing nanomaterials
Zhakin et al. The experimental study of charged meniscuses
Wadhwa et al. Improving run-time stability with aerosol jet printing using a solvent add-back bubbler
Rebollo-Muñoz et al. A hybrid flow focusing nozzle design to produce micron and sub-micron capillary jets
Wang et al. A full voltage-controlled nanoelectrospray system and its steady characteristic analysed by empirically equivalent circuit method
Arumuganathar et al. Versatile methodology for generating size-controlled composite micrometer beads capsulating nanomaterials
He et al. Production of ultrafine particles with nanometer size distribution via a bubble film bursting method
Huang et al. Nanoparticle and microparticle generation with super-or near-critical carbon dioxide
Wang et al. Mechanisms and characteristics of spray formation with flow focusing in a new air-assist micro-atomizer