ATE323885T1 - Immobilisierung von oligonukleotiden durch kovalente bindung - Google Patents

Immobilisierung von oligonukleotiden durch kovalente bindung

Info

Publication number: ATE323885T1
Authority: AT; Austria
Prior art keywords: group; reacting; oligonucleotides; immobilization; biomolecules
Prior art date: 2001-07-16

Application number

AT01202713T

Other languages

English (en)

Inventor

Kan-Hung Lee

Kang-Jehng Chen

Hsing Hsiao

Shin-Hwan Wang

Original Assignee

Dr Chip Biotechnology Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-07-16

Filing date

2001-07-16

Publication date

2006-05-15

2001-07-16 Application filed by Dr Chip Biotechnology Inc filed Critical Dr Chip Biotechnology Inc

2006-05-15 Application granted granted Critical

2006-05-15 Publication of ATE323885T1 publication Critical patent/ATE323885T1/de

Links

108091034117 Oligonucleotide Proteins 0.000 title 1
JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 title 1
239000007790 solid phase Substances 0.000 abstract 2
VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
239000007787 solid Substances 0.000 abstract 1
239000000126 substance Substances 0.000 abstract 1
239000000758 substrate Substances 0.000 abstract 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
- G01N33/545—Synthetic resin
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent

Landscapes

Health & Medical Sciences (AREA)
Immunology (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Chemical & Material Sciences (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Cell Biology (AREA)
Food Science & Technology (AREA)
Medicinal Chemistry (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Microbiology (AREA)
General Health & Medical Sciences (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Apparatus Associated With Microorganisms And Enzymes (AREA)

AT01202713T 2001-07-16 2001-07-16 Immobilisierung von oligonukleotiden durch kovalente bindung ATE323885T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP01202713A EP1278063B1 (de)	2001-07-16	2001-07-16	Immobilisierung von Oligonukleotiden durch kovalente Bindung

Publications (1)

Publication Number	Publication Date
ATE323885T1 true ATE323885T1 (de)	2006-05-15

Family

ID=8180644

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT01202713T ATE323885T1 (de)	2001-07-16	2001-07-16	Immobilisierung von oligonukleotiden durch kovalente bindung

Country Status (4)

Country	Link
EP (1)	EP1278063B1 (de)
AT (1)	ATE323885T1 (de)
DE (1)	DE60118901T2 (de)
ES (1)	ES2262601T3 (de)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4933410A (en) *	1989-03-29	1990-06-12	Applied Immunesciences, Inc.	Covalent attachment of macromolecules on substrate surfaces
EP0403700B1 (de) *	1989-06-20	1992-08-05	J.T. Baker Inc.	Polyethylenimin-Matrizen für Affinitätschromatographie
JPH03237147A (ja) *	1990-02-14	1991-10-23	Mitsubishi Kasei Vinyl Co	農業用塩化ビニル系樹脂フイルム
EP1035218A1 (de) *	1999-03-03	2000-09-13	BioChip Technologies GmbH	Immobilisierung von Molekülen an Oberflächen über verzweigte Polymerketten
WO2001016372A1 (en) *	1999-08-27	2001-03-08	Matrix Technologies Corporation	Methods of immobilizing ligands on solid supports and apparatus and methods of use therefor
EP1242460B1 (de) *	1999-11-29	2006-10-18	Unilever Plc	Immobilisierung von proteinen mit hilfe eines polypeptidsegments

2001
- 2001-07-16 AT AT01202713T patent/ATE323885T1/de not_active IP Right Cessation
- 2001-07-16 EP EP01202713A patent/EP1278063B1/de not_active Expired - Lifetime
- 2001-07-16 DE DE60118901T patent/DE60118901T2/de not_active Expired - Lifetime
- 2001-07-16 ES ES01202713T patent/ES2262601T3/es not_active Expired - Lifetime

Also Published As

Publication number	Publication date
DE60118901T2 (de)	2006-11-23
DE60118901D1 (de)	2006-05-24
EP1278063A1 (de)	2003-01-22
EP1278063B1 (de)	2006-04-19
ES2262601T3 (es)	2006-12-01

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Legal Events

Date	Code	Title	Description
2006-10-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties