ATE324107T1 - Carbamat-verbindungen zur prävention oder behandlung von angstzuständen - Google Patents

Carbamat-verbindungen zur prävention oder behandlung von angstzuständen

Info

Publication number: ATE324107T1
Authority: AT; Austria
Prior art keywords: group; phenyl; alkyl; carbamat; anxiety
Prior art date: 2001-02-27

Application number

AT02759750T

Other languages

English (en)

Inventor

Carlos R Plata-Salaman

Boyu Zhao

Roy E Twyman

Original Assignee

Ortho Mcneil Pharm Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-02-27

Filing date

2002-02-21

Publication date

2006-05-15

2002-02-21 Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc

2006-05-15 Application granted granted Critical

2006-05-15 Publication of ATE324107T1 publication Critical patent/ATE324107T1/de

Links

208000019901 Anxiety disease Diseases 0.000 title abstract 2
KXDHJXZQYSOELW-UHFFFAOYSA-M Carbamate Chemical class NC([O-])=O KXDHJXZQYSOELW-UHFFFAOYSA-M 0.000 title 1
230000036506 anxiety Effects 0.000 title 1
230000002265 prevention Effects 0.000 title 1
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 3
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 1
WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
229910052794 bromium Inorganic materials 0.000 abstract 1
229910052801 chlorine Inorganic materials 0.000 abstract 1
239000000460 chlorine Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 1
229910052731 fluorine Inorganic materials 0.000 abstract 1
239000011737 fluorine Substances 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
150000002367 halogens Chemical group 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
229910052740 iodine Inorganic materials 0.000 abstract 1
239000011630 iodine Substances 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Epidemiology (AREA)
Emergency Medicine (AREA)
Anesthesiology (AREA)
Psychiatry (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

AT02759750T 2001-02-27 2002-02-21 Carbamat-verbindungen zur prävention oder behandlung von angstzuständen ATE324107T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US27168901P	2001-02-27	2001-02-27

Publications (1)

Publication Number	Publication Date
ATE324107T1 true ATE324107T1 (de)	2006-05-15

Family

ID=23036639

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT02759750T ATE324107T1 (de)	2001-02-27	2002-02-21	Carbamat-verbindungen zur prävention oder behandlung von angstzuständen

Country Status (25)

Country	Link
US (3)	US7078436B2 (de)
EP (1)	EP1399144B1 (de)
JP (1)	JP2004523554A (de)
KR (1)	KR20030078947A (de)
CN (1)	CN1503665A (de)
AT (1)	ATE324107T1 (de)
AU (1)	AU2002306567B2 (de)
BR (1)	BR0207830A (de)
CA (1)	CA2439286A1 (de)
CY (1)	CY1107468T1 (de)
CZ (1)	CZ20032311A3 (de)
DE (1)	DE60210960T2 (de)
DK (1)	DK1399144T3 (de)
ES (1)	ES2262826T3 (de)
HU (1)	HUP0303262A2 (de)
IL (1)	IL157594A0 (de)
MX (1)	MXPA03007720A (de)
MY (1)	MY136391A (de)
NO (1)	NO20033800L (de)
NZ (1)	NZ546549A (de)
PL (1)	PL364639A1 (de)
PT (1)	PT1399144E (de)
RS (1)	RS50505B (de)
RU (1)	RU2292881C2 (de)
WO (1)	WO2002067923A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MXPA03007720A (es) *	2001-02-27	2004-11-12	Johnson & Johnson	Compuestos de carbamato para su uso en la prevencion o el tratamiento de transtornos de ansiedad.
JP2008528489A (ja)	2005-01-20	2008-07-31	ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ	Ｑｔ間隔調節方法
ES2435403T3 (es)	2005-06-08	2013-12-19	Sk Biopharmaceuticals Co., Ltd.	Tratamiento de trastornos del sueño y vigilia
JP2010508279A (ja) *	2006-10-27	2010-03-18	ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ	破壊的行動障害の処置法
US8263652B2 (en)	2007-10-31	2012-09-11	Sk Biopharmaceuticals Co., Ltd.	Stabilized pediatric suspension of carisbamate
US8609849B1 (en)	2010-11-30	2013-12-17	Fox Chase Chemical Diversity Center, Inc.	Hydroxylated sulfamides exhibiting neuroprotective action and their method of use
ES2998534T3 (en)	2013-03-12	2025-02-20	Bio Pharm Solutions Co Ltd	Phenyl carbamate compounds for use in preventing or treating pediatric epilesy
US9907776B2 (en)	2013-03-12	2018-03-06	Bio-Pharm Solutions, Co., Ltd.	Phenyl carbamate compound and a composition for preventing or treating a psychiatric disorder comprising the same
JP6807941B2 (ja) *	2016-02-29	2021-01-06	バイオ−ファームソリューションズカンパニーリミテッド	スルファメート誘導体化合物、その製造方法および用途
US10195151B2 (en)	2016-09-06	2019-02-05	Jazz Pharmaceuticals International Iii Limited	Formulations of (R)-2-amino-3-phenylpropyl carbamate
KR102900173B1 (ko) *	2016-12-14	2025-12-12	에스케이바이오팜 주식회사	조현병, 강박장애 및 투렛증후군으로부터 선택되는 정신증 장애의 예방, 경감 또는 치료에 있어서의 카바메이트 화합물의 용도
AU2018278332B2 (en)	2017-06-02	2022-05-19	Jazz Pharmaceuticals Ireland Limited	Methods and compositions for treating excessive sleepiness
US10940133B1 (en)	2020-03-19	2021-03-09	Jazz Pharmaceuticals Ireland Limited	Methods of providing solriamfetol therapy to subjects with impaired renal function

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3313692A (en)	1958-04-21	1967-04-11	Armour Pharma	Method of inducing calming and muscle relaxation with carbamates
US3278380A (en) *	1962-02-06	1966-10-11	Armour Pharma	Methods of calming employing diphenyl hydroxy carbamate compounds
US3248418A (en)	1962-06-26	1966-04-26	Charles D Bossinger	2-hydroxy-2-phenyl alkyl carbamates
US3265728A (en) *	1962-07-18	1966-08-09	Armour Pharma	Substituted phenethyl carbamates
CN1109880A (zh) *	1994-02-03	1995-10-11	合成实验室公司	3-(2-氨基乙基)-4-[3-(三氟甲基)苯甲酰基]-3，4-二氢-2h-1，4-苯并噁嗪衍生物、制备及其应用
US5698588A (en) *	1996-01-16	1997-12-16	Yukong Limited	Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol
CZ302412B6 (cs)	2001-02-27	2011-05-04	Ortho-Mcneil Pharmaceutical, Inc.	Lécivo pro prevenci nebo lécbu psychotických chorob
MXPA03007720A (es) *	2001-02-27	2004-11-12	Johnson & Johnson	Compuestos de carbamato para su uso en la prevencion o el tratamiento de transtornos de ansiedad.
CA2439475C (en)	2001-02-27	2010-05-18	Carlos R. Plata-Salaman	Carbamate compounds for use in preventing or treating bipolar disorder

2002
- 2002-02-21 MX MXPA03007720A patent/MXPA03007720A/es active IP Right Grant
- 2002-02-21 KR KR10-2003-7011293A patent/KR20030078947A/ko not_active Ceased
- 2002-02-21 RS YUP-679/03A patent/RS50505B/sr unknown
- 2002-02-21 BR BR0207830-9A patent/BR0207830A/pt not_active IP Right Cessation
- 2002-02-21 PT PT02759750T patent/PT1399144E/pt unknown
- 2002-02-21 ES ES02759750T patent/ES2262826T3/es not_active Expired - Lifetime
- 2002-02-21 AT AT02759750T patent/ATE324107T1/de active
- 2002-02-21 PL PL02364639A patent/PL364639A1/xx not_active Application Discontinuation
- 2002-02-21 JP JP2002567290A patent/JP2004523554A/ja active Pending
- 2002-02-21 CA CA002439286A patent/CA2439286A1/en not_active Abandoned
- 2002-02-21 IL IL15759402A patent/IL157594A0/xx unknown
- 2002-02-21 US US10/081,713 patent/US7078436B2/en not_active Expired - Fee Related
- 2002-02-21 CN CNA028087143A patent/CN1503665A/zh active Pending
- 2002-02-21 NZ NZ546549A patent/NZ546549A/en not_active IP Right Cessation
- 2002-02-21 HU HU0303262A patent/HUP0303262A2/hu unknown
- 2002-02-21 RU RU2003128986/14A patent/RU2292881C2/ru not_active IP Right Cessation
- 2002-02-21 DE DE60210960T patent/DE60210960T2/de not_active Expired - Lifetime
- 2002-02-21 DK DK02759750T patent/DK1399144T3/da active
- 2002-02-21 EP EP02759750A patent/EP1399144B1/de not_active Expired - Lifetime
- 2002-02-21 WO PCT/US2002/005423 patent/WO2002067923A1/en not_active Ceased
- 2002-02-21 AU AU2002306567A patent/AU2002306567B2/en not_active Ceased
- 2002-02-21 CZ CZ20032311A patent/CZ20032311A3/cs unknown
- 2002-02-27 MY MYPI20020693A patent/MY136391A/en unknown
2003
- 2003-08-26 NO NO20033800A patent/NO20033800L/no not_active Application Discontinuation
2005
- 2005-08-01 US US11/194,251 patent/US20050267203A1/en not_active Abandoned
2006
- 2006-06-21 CY CY20061100843T patent/CY1107468T1/el unknown
2009
- 2009-06-01 US US12/475,815 patent/US20090234003A1/en not_active Abandoned

Also Published As

Publication number	Publication date
CN1503665A (zh)	2004-06-09
CY1107468T1 (el)	2012-12-19
AU2002306567B2 (en)	2006-08-17
US20020143053A1 (en)	2002-10-03
US7078436B2 (en)	2006-07-18
PT1399144E (pt)	2006-07-31
DK1399144T3 (da)	2006-07-24
NZ546549A (en)	2007-11-30
EP1399144B1 (de)	2006-04-26
US20050267203A1 (en)	2005-12-01
BR0207830A (pt)	2004-06-22
PL364639A1 (en)	2004-12-13
HK1062270A1 (en)	2004-10-29
RS50505B (sr)	2010-03-02
US20090234003A1 (en)	2009-09-17
RU2292881C2 (ru)	2007-02-10
JP2004523554A (ja)	2004-08-05
NO20033800D0 (no)	2003-08-26
KR20030078947A (ko)	2003-10-08
MXPA03007720A (es)	2004-11-12
DE60210960D1 (de)	2006-06-01
NO20033800L (no)	2003-09-26
IL157594A0 (en)	2004-03-28
HUP0303262A2 (hu)	2004-01-28
RU2003128986A (ru)	2005-03-20
CA2439286A1 (en)	2002-09-06
ES2262826T3 (es)	2006-12-01
DE60210960T2 (de)	2006-11-16
WO2002067923A1 (en)	2002-09-06
CZ20032311A3 (cs)	2005-02-16
EP1399144A1 (de)	2004-03-24
YU67903A (sh)	2006-08-17
MY136391A (en)	2008-09-30

Legal Events

Date

Code

Title

Description

2007-01-15

UEP

Publication of translation of european patent specification

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Country of ref document: EP

Publication	Publication Date	Title
YU67703A (sh)	2006-08-17	Karbamatna jedinjenja za upotrebu u sprečavanju ili lečenju poremećaja kretanja
MY138156A (en)	2009-04-30	Carbamate compounds for use in preventing or treating neurodegenerative disorders
ATE324108T1 (de)	2006-05-15	Carbamatverbindungen zur verwendung bei der prävention oder behandlung der bipolaren erkrankung
ATE324107T1 (de)	2006-05-15	Carbamat-verbindungen zur prävention oder behandlung von angstzuständen
DE602005020667D1 (de)	2010-05-27	Verwendung von 2-phenyl-1,2-ethanediol-(di)carbamaten zur behandlung von epileptogenese
ATE378046T1 (de)	2007-11-15	Carbamatverbindungen zur vorbeugung oder behandlung bipolarer erkrankungen
MY129312A (en)	2007-03-30	Carbamate compounds for use in the treatment of pain
ATE538784T1 (de)	2012-01-15	Verfahren zur behandlung von substanzbedingten erkrankungen
ATE267629T1 (de)	2004-06-15	Verwendung von carbamat verbindungen zur vorbeugung oder behandlung von neuropathischen- , cluster- und migräneartigen kopfschmerzen
ATE435014T1 (de)	2009-07-15	Carbamate verbindungen zur vorbeugung oder behandlung von neuropathischen schmerzen
MY136733A (en)	2008-11-28	Carbamate compounds for use in preventing or treating psychotic disorders
MY136347A (en)	2008-09-30	Carbamate compounds for use in preventing or treating neuropathic pain and cluster and migraine headache-associated pain