ATE324373T1 - Immunmodulierende verbindungen - Google Patents

Immunmodulierende verbindungen

Info

Publication number: ATE324373T1
Authority: AT; Austria
Prior art keywords: compound; relates; present; novel heterocyclic; immunomodulating compounds
Prior art date: 2001-07-04

Application number

AT02746260T

Other languages

English (en)

Inventor

Per Axel Bjoerk

Tomas Fex

Lars Olof Goeran Pettersson

Poul Sorensen

Graca Thrige Dorthe Da

Original Assignee

Active Biotech Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-07-04

Filing date

2002-07-02

Publication date

2006-05-15

2002-07-02 Application filed by Active Biotech Ab filed Critical Active Biotech Ab

2006-05-15 Application granted granted Critical

2006-05-15 Publication of ATE324373T1 publication Critical patent/ATE324373T1/de

Links

150000001875 compounds Chemical class 0.000 title abstract 3
230000002519 immonomodulatory effect Effects 0.000 title abstract 2
101000914484 Homo sapiens T-lymphocyte activation antigen CD80 Proteins 0.000 abstract 2
102100027222 T-lymphocyte activation antigen CD80 Human genes 0.000 abstract 2
150000002391 heterocyclic compounds Chemical class 0.000 abstract 2
101000914514 Homo sapiens T-cell-specific surface glycoprotein CD28 Proteins 0.000 abstract 1
201000004681 Psoriasis Diseases 0.000 abstract 1
102100027213 T-cell-specific surface glycoprotein CD28 Human genes 0.000 abstract 1
239000005557 antagonist Substances 0.000 abstract 1
208000006673 asthma Diseases 0.000 abstract 1
206010012601 diabetes mellitus Diseases 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
230000003993 interaction Effects 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
201000006417 multiple sclerosis Diseases 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
201000000596 systemic lupus erythematosus Diseases 0.000 abstract 1
238000002054 transplantation Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Immunology (AREA)
Diabetes (AREA)
Rheumatology (AREA)
Pulmonology (AREA)
Emergency Medicine (AREA)
Physical Education & Sports Medicine (AREA)
Transplantation (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Obesity (AREA)
Orthopedic Medicine & Surgery (AREA)
Hematology (AREA)
Endocrinology (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

AT02746260T 2001-07-04 2002-07-02 Immunmodulierende verbindungen ATE324373T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
SE0102404A SE0102404D0 (sv)	2001-07-04	2001-07-04	Novel immunomodulating compounds

Publications (1)

Publication Number	Publication Date
ATE324373T1 true ATE324373T1 (de)	2006-05-15

Family

ID=20284743

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT02746260T ATE324373T1 (de)	2001-07-04	2002-07-02	Immunmodulierende verbindungen

Country Status (20)

Country	Link
EP (1)	EP1409485B1 (de)
JP (1)	JP2005501033A (de)
CN (1)	CN1249063C (de)
AT (1)	ATE324373T1 (de)
AU (1)	AU2002315996B2 (de)
BR (1)	BR0210776A (de)
CA (1)	CA2451749A1 (de)
DE (1)	DE60210977T2 (de)
ES (1)	ES2258150T3 (de)
HR (1)	HRP20031055B1 (de)
HU (1)	HUP0401204A3 (de)
MX (1)	MXPA04000017A (de)
NO (1)	NO20035684L (de)
NZ (1)	NZ530316A (de)
PL (1)	PL367637A1 (de)
RU (1)	RU2004103079A (de)
SE (1)	SE0102404D0 (de)
WO (1)	WO2003004495A1 (de)
YU (1)	YU101603A (de)
ZA (1)	ZA200309806B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2004048378A1 (en)	2002-11-22	2004-06-10	Active Biotech Ab	Pyrazoloquinolines with immunomodulating activity
EP1572689B1 (de) *	2002-12-16	2009-03-11	Active Biotech AB	Tetrazyklische immunmodulierende verbindungen
BRPI0408365B8 (pt)	2003-03-14	2021-05-25	Avidex Ltd	compostos heterocíclicos de imunomodulação
GB0305876D0 (en) *	2003-03-14	2003-04-16	Avidex Ltd	Immuno inhibitory heterocyclic compounds
GB0325644D0 (en)	2003-11-04	2003-12-10	Avidex Ltd	Immuno ihibitory pyrazolone compounds
JPWO2005068467A1 (ja)	2004-01-14	2007-12-27	味の素株式会社	新規縮環化合物
GB0411770D0 (en) *	2004-05-26	2004-06-30	Avidex Ltd	Immuno inhibitory heterocyclic compouds
CN1997645B (zh) *	2004-08-09	2012-05-23	麦迪金股份公司	免疫调节作为cd80抑制剂的氧代吡唑并噌啉类
CN101863903B (zh) *	2010-06-08	2014-03-12	沈阳药科大学	1,4-二氢噻吩并[3’,2’:5,6]噻喃并[4,3-c]吡唑-3-羧酸衍生物及其应用
KR102318498B1 (ko) *	2013-06-24	2021-10-27	메르크 파텐트 게엠베하	Fshr의 조절인자로서의 피라졸 화합물 및 이의 용도
EP2883883A1 (de)	2013-12-16	2015-06-17	Cardio3 Biosciences S.A.	Therapeutische Ziele und Mittel zur Behandlung von ischämiebedingten Reperfusionsschäden
CN107075612A (zh)	2014-07-08	2017-08-18	阿瓦塔纳有限公司	从含钛矿物提取产物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4268516A (en) *	1978-10-11	1981-05-19	Pfizer Inc.	[1]Benzothiopyrano[4,3-c]pyrazoles as immunoregulatory agents
US4312870A (en) *	1979-06-21	1982-01-26	Ciba-Geigy Corporation	Pyrazoloquinolines
ZA895646B (en) *	1988-08-09	1990-04-25	Boots Co Plc	Therapeutic agents
GB8818895D0 (en) *	1988-08-09	1988-09-14	Boots Co Plc	Therapeutic agents
SE8903564D0 (sv) *	1989-10-26	1989-10-26	Pharmacia Ab	New use condensed quinoline compound
EP0539372A1 (de) *	1990-02-02	1993-05-05	The Boots Company PLC	Therapeutische mittel
AR006520A1 (es) *	1996-03-20	1999-09-08	Astra Pharma Prod	Derivados de 2-arilpirazolisoquinolina y cinolinona y procedimiento para su preparacion.

2001
- 2001-07-04 SE SE0102404A patent/SE0102404D0/xx unknown
2002
- 2002-07-02 NZ NZ530316A patent/NZ530316A/en unknown
- 2002-07-02 AT AT02746260T patent/ATE324373T1/de not_active IP Right Cessation
- 2002-07-02 JP JP2003510662A patent/JP2005501033A/ja not_active Withdrawn
- 2002-07-02 WO PCT/SE2002/001309 patent/WO2003004495A1/en not_active Ceased
- 2002-07-02 HU HU0401204A patent/HUP0401204A3/hu unknown
- 2002-07-02 YU YU101603A patent/YU101603A/sh unknown
- 2002-07-02 HR HR20031055A patent/HRP20031055B1/xx not_active IP Right Cessation
- 2002-07-02 CA CA002451749A patent/CA2451749A1/en not_active Abandoned
- 2002-07-02 MX MXPA04000017A patent/MXPA04000017A/es active IP Right Grant
- 2002-07-02 DE DE60210977T patent/DE60210977T2/de not_active Expired - Lifetime
- 2002-07-02 AU AU2002315996A patent/AU2002315996B2/en not_active Ceased
- 2002-07-02 ES ES02746260T patent/ES2258150T3/es not_active Expired - Lifetime
- 2002-07-02 BR BR0210776-7A patent/BR0210776A/pt not_active IP Right Cessation
- 2002-07-02 RU RU2004103079/04A patent/RU2004103079A/ru not_active Application Discontinuation
- 2002-07-02 EP EP02746260A patent/EP1409485B1/de not_active Expired - Lifetime
- 2002-07-02 PL PL02367637A patent/PL367637A1/xx not_active Application Discontinuation
- 2002-07-02 CN CNB028132890A patent/CN1249063C/zh not_active Expired - Fee Related
2003
- 2003-12-19 NO NO20035684A patent/NO20035684L/no not_active Application Discontinuation
- 2003-12-19 ZA ZA200309806A patent/ZA200309806B/en unknown

Also Published As

Publication number	Publication date
AU2002315996B2 (en)	2007-11-29
CN1249063C (zh)	2006-04-05
DE60210977T2 (de)	2006-09-21
EP1409485B1 (de)	2006-04-26
HRP20031055A2 (en)	2004-06-30
EP1409485A1 (de)	2004-04-21
BR0210776A (pt)	2004-07-20
HK1066809A1 (en)	2005-04-01
HRP20031055B1 (hr)	2008-01-31
HUP0401204A2 (hu)	2004-10-28
HUP0401204A3 (en)	2008-03-28
NO20035684D0 (no)	2003-12-19
YU101603A (en)	2006-05-25
WO2003004495A1 (en)	2003-01-16
CN1522254A (zh)	2004-08-18
NZ530316A (en)	2004-08-27
PL367637A1 (en)	2005-03-07
ZA200309806B (en)	2004-12-20
RU2004103079A (ru)	2005-06-10
CA2451749A1 (en)	2003-01-16
JP2005501033A (ja)	2005-01-13
DE60210977D1 (de)	2006-06-01
MXPA04000017A (es)	2004-05-21
SE0102404D0 (sv)	2001-07-04
NO20035684L (no)	2004-03-02
ES2258150T3 (es)	2006-08-16

Legal Events

Date	Code	Title	Description
2006-10-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
SI1480961T1 (sl)	2007-06-30	Inhibitorji dpiv na osnovi glutaminila
MX2021001433A (es)	2021-04-12	Nuevos compuestos heterociclicos como inhibidores de la monoacilglicerol lipasa.
ATE324373T1 (de)	2006-05-15	Immunmodulierende verbindungen
WO2005092895A3 (en)	2006-03-02	Alpha aryl or heteroaryl methyl beta piperidino propanoic acid compounds as orl1-receptor antagonists
DE602004021472D1 (en)	2009-07-23	Pyrimiidinverbindungen
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BR0311343A (pt)	2005-03-22	Derivados de piridazina
WO2008045393A3 (en)	2008-06-12	Imidazo- and triazolo-pyridine compounds and methods of use therof
SE0200920D0 (sv)	2002-03-25	Novel compounds
TNSN05105A1 (en)	2007-05-14	Novel bicyclic inhibitors of hormone sensitive lipase
SE0200919D0 (sv)	2002-03-25	Chemical compounds
PL371127A1 (en)	2005-06-13	6-aminomorphinane derivatives, method for the production and use thereof
ZA200506422B (en)	2007-02-28	Substituted 4-phenyltetrahydroisoquinolines, method for the production thereof, the use of the same as medicaments, and medicament containing such compounds
WO2003087062A3 (en)	2003-11-20	4-(heterocyclyl)-benzenesulfoximine compounds for the treatment of inflammation
ATE353898T1 (de)	2007-03-15	Pyrazolochinoline mit immunmodulierenderwirkung
WO2004087652A3 (en)	2005-02-10	Imidazotriazine compounds
GB0412314D0 (en)	2004-07-07	Compounds
WO2005085236A3 (en)	2005-10-20	Caspase inhibitors and uses thereof
ATE425164T1 (de)	2009-03-15	Tetrazyklische immunmodulierende verbindungen
MXPA04000978A (es)	2004-04-20	Procedimiento para la produccion de 4-amino-2,5-bisheterociclilquinazolinas.
WO2003080631A3 (en)	2004-04-15	Plasma carboxypeptidase b inhibitors
GB0103045D0 (en)	2001-03-21	Organic Compounds
WO2003076426A3 (en)	2004-07-22	Pyridinyloxy derivatives as 5-ht receptor ligands
DE502004009136D1 (de)	2009-04-23	NEUE HETEROARYLSUBSTITUIERTE ACETONDERIVATE ALS HEMMSTOFFE DER PHOSPHOLIPASE A sb 2 /sb
ATE327987T1 (de)	2006-06-15	Methylthiophencarboxanilide