ATE324896T1 - Antimikrobielle zusammensetzungen enthaltend taurolidin, zitronensäure und natriumzitrat - Google Patents
Antimikrobielle zusammensetzungen enthaltend taurolidin, zitronensäure und natriumzitratInfo
- Publication number
- ATE324896T1 ATE324896T1 AT99959111T AT99959111T ATE324896T1 AT E324896 T1 ATE324896 T1 AT E324896T1 AT 99959111 T AT99959111 T AT 99959111T AT 99959111 T AT99959111 T AT 99959111T AT E324896 T1 ATE324896 T1 AT E324896T1
- Authority
- AT
- Austria
- Prior art keywords
- citric acid
- compositions containing
- sodium citrate
- antimicrobial compositions
- containing taurolidine
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/549—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame having two or more nitrogen atoms in the same ring, e.g. hydrochlorothiazide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- External Artificial Organs (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9149198P | 1998-07-02 | 1998-07-02 | |
| US09/307,916 US6166007A (en) | 1998-07-02 | 1999-05-10 | Antimicrobial locks comprising taurinamide derivatives and carboxylic acids and/or salts thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE324896T1 true ATE324896T1 (de) | 2006-06-15 |
Family
ID=26784016
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99959111T ATE324896T1 (de) | 1998-07-02 | 1999-05-28 | Antimikrobielle zusammensetzungen enthaltend taurolidin, zitronensäure und natriumzitrat |
Country Status (7)
| Country | Link |
|---|---|
| US (4) | US6166007A (de) |
| EP (1) | EP1089738B2 (de) |
| AT (1) | ATE324896T1 (de) |
| AU (1) | AU4319699A (de) |
| DE (1) | DE69931159T3 (de) |
| ES (1) | ES2264274T5 (de) |
| WO (1) | WO2000001391A1 (de) |
Families Citing this family (68)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9626795D0 (en) | 1996-12-23 | 1997-02-12 | Geistlich Soehne Ag | Combating infection in delivery systems |
| US20050124608A1 (en) * | 2001-04-03 | 2005-06-09 | Redmond H. P. | Treatment of cancers |
| US8304390B2 (en) * | 1997-07-31 | 2012-11-06 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Method of treatment for preventing or reducing tumor growth in the liver of patient |
| US7132413B1 (en) * | 1997-07-31 | 2006-11-07 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Anticoagulant/sterilizing compositions and methods |
| US6166007A (en) * | 1998-07-02 | 2000-12-26 | Sodemann; Klaus | Antimicrobial locks comprising taurinamide derivatives and carboxylic acids and/or salts thereof |
| US6958049B1 (en) * | 1998-08-25 | 2005-10-25 | Ash Access Technology, Inc. | Method of enhancing catheter patency using a citrate salt catheter lock solution |
| US6608051B1 (en) * | 1999-03-12 | 2003-08-19 | Medpointe Healthcare Inc. | Compositions and methods for treating blood |
| CA2302720C (en) * | 1999-03-29 | 2009-07-14 | Ed Geistlich Sohne Ag Fur Chemische Industrie | Anticoagulant/sterilizing compositions and methods |
| US7345039B2 (en) * | 1999-06-04 | 2008-03-18 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Enhancement of effectiveness of 5-fluorouracil in treatment of tumor metastases and cancer |
| US7892530B2 (en) * | 1999-06-04 | 2011-02-22 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Treatment of tumor metastases and cancer |
| US8030301B2 (en) * | 1999-06-04 | 2011-10-04 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Treatment of cancers with methylol-containing compounds and at least one electrolyte |
| US6592564B2 (en) * | 1999-07-23 | 2003-07-15 | Vasca, Inc. | Methods and kits for locking and disinfecting implanted catheters |
| US6685694B2 (en) | 1999-07-23 | 2004-02-03 | Vasca, Inc. | Methods and kits for locking and disinfecting implanted catheters |
| US6679870B1 (en) | 1999-07-23 | 2004-01-20 | Vasca, Inc. | Methods and kits for locking and disinfecting implanted catheters |
| US6641571B2 (en) * | 2000-01-05 | 2003-11-04 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Reduction of postoperative complications of cardiopulmonary bypass (CPB) surgery |
| US6350251B1 (en) * | 2000-01-18 | 2002-02-26 | Biolink Corporation | Biocidal locks |
| WO2001095876A1 (en) * | 2000-06-09 | 2001-12-20 | Baylor College Of Medicine | The combination of antimicrobial agents and bacterial interference to coat medical devices |
| US6423050B1 (en) * | 2000-06-16 | 2002-07-23 | Zbylut J. Twardowski | Method and apparatus for locking of central-vein catheters |
| DE10029185A1 (de) * | 2000-06-19 | 2002-01-03 | Henkel Kgaa | Verfahren zur antimikrobiellen Behandlung von durch mikrobiellen Befallgefährdeten Materialien |
| US20050101012A1 (en) | 2001-03-12 | 2005-05-12 | Gerold Schuler | CD4+CD25+ regulatory T cells from human blood |
| EP1245247A1 (de) * | 2001-03-28 | 2002-10-02 | Biolink Corporation | Biozidschleuse |
| US20040092890A1 (en) * | 2001-05-10 | 2004-05-13 | Ash Stephen R. | Catheter lock solution including a photo-oxidant |
| US20050215978A1 (en) * | 2001-05-25 | 2005-09-29 | Ash Stephen R | Method of enhancing catheter patency using a citrate salt catheter lock solution |
| US6589591B1 (en) * | 2001-07-10 | 2003-07-08 | Baylor College Of Medicine | Method for treating medical devices using glycerol and an antimicrobial agent |
| NZ533029A (en) * | 2001-11-26 | 2006-05-26 | Genentech Inc | Composition useful for removal of fibrin-bound blood clot from a catheter comprises water, a plasminogen activator and an alcohol |
| JP4165754B2 (ja) * | 2001-12-05 | 2008-10-15 | タイコ・ヘルスケアー・グループ・エルピー | 抗菌性システムおよび方法 |
| US8541472B2 (en) * | 2001-12-05 | 2013-09-24 | Aseptica, Inc. | Antiseptic compositions, methods and systems |
| CN1301110C (zh) * | 2002-04-01 | 2007-02-21 | Nd合伙人股份有限公司 | 包含牛磺酰胺衍生物及羧酸和/或其盐的抗微生物闭锁 |
| US6803363B2 (en) * | 2002-05-31 | 2004-10-12 | Nd Partners, Llc | Peritoneal dialysis solution with taurolidine |
| US8222033B2 (en) | 2002-08-12 | 2012-07-17 | Argos Therapeutics, Inc. | CD4+CD25− T cells and Tr1-like regulatory T cells |
| ATE354380T1 (de) * | 2003-02-03 | 2007-03-15 | Polaschegg Hans-Dietrich Dr Te | Zusammensetzung zur prävention von infektionen durch subkutane prothesen |
| US20040256561A1 (en) * | 2003-06-17 | 2004-12-23 | Allyson Beuhler | Wide band light sensing pixel array |
| EP1555162A1 (de) | 2004-01-14 | 2005-07-20 | Sumitomo Wiring Systems, Ltd. | Struktur zum Befestigen einen Türkabelstrang |
| EP1737378A2 (de) * | 2004-04-02 | 2007-01-03 | Baylor College of Medicine | Neue modifizierung von medizinischen prothesen |
| SE0401568D0 (sv) * | 2004-06-17 | 2004-06-17 | Gambro Lundia Ab | A lock solution for medical devices, a device and a method for the application thereof |
| US7696182B2 (en) * | 2004-11-02 | 2010-04-13 | Nd Partners, Llc | Antimicrobial locking solutions comprising taurinamide derivatives and biologically acceptable salts and acids, with the addition of small concentrations of heparin |
| US7749529B2 (en) * | 2005-02-08 | 2010-07-06 | Ash Access Technology, Inc. | Catheter lock solution comprising citrate and a paraben |
| CA2624677A1 (en) * | 2005-10-06 | 2007-04-19 | Novacal Pharmaceuticals, Inc. | System and method for the prevention of bacterial and fungal infections including urinary tract infections (uti) using n-halogenated amino acids |
| US8007488B2 (en) | 2005-11-10 | 2011-08-30 | Phase One Medical Llc | Catheter device |
| US9192755B2 (en) | 2005-11-10 | 2015-11-24 | Phase One Medical, Llc | Catheter device |
| KR20160023926A (ko) * | 2006-02-28 | 2016-03-03 | 벡톤 디킨슨 앤드 컴퍼니 | 카테테르 잠금을 위한 항미생물성 조성물 및 방법 |
| US8167847B2 (en) | 2006-06-22 | 2012-05-01 | Excelsior Medical Corporation | Antiseptic cap and antiseptic cap equipped plunger and syringe barrel assembly |
| ES2318628T3 (es) | 2006-07-25 | 2009-05-01 | Claus Herdeis | Preparacion de formulaciones antimicrobianas que comprenden 7-oxa-2-tia-1,5 diazabiciclo(3.3.1)-nonan-2,2-diona. |
| US20100010086A1 (en) * | 2006-08-04 | 2010-01-14 | Ash Stephen R | Antimicrobial therapy for indwelling catheters and for sanitizing surfaces |
| CA2668347C (en) | 2006-11-07 | 2017-06-20 | Genentech, Inc. | Tissue plasminogen activator variant uses |
| US7798999B2 (en) * | 2007-06-05 | 2010-09-21 | Cook Incorporated | Adjustable length catheter |
| US20090041727A1 (en) * | 2007-08-08 | 2009-02-12 | Conjugon, Inc. | Compositions and Methods for Microbe Storage and Delivery |
| US8389583B2 (en) * | 2008-05-23 | 2013-03-05 | Zurex Pharma, Inc. | Antimicrobial compositions and methods of use |
| KR20110096539A (ko) * | 2008-12-05 | 2011-08-30 | 가부시끼가이샤 제이엠에스 | 아세트산을 함유하는 혈관 내에 유치된 카테터의 로크 용액 및 그 로크 용액을 수납한 용기 |
| US20100249747A1 (en) * | 2009-03-26 | 2010-09-30 | Organic Medical Ventures, L.L.C. | Transdermal venous access locking solution |
| US9433209B2 (en) * | 2009-03-26 | 2016-09-06 | Organic Medical Ventures, L.L.C. | Transdermal venous access locking solutions |
| US9427498B2 (en) * | 2009-03-26 | 2016-08-30 | Organic Medical Ventures, L.L.C. | Syringe treated with transdermal venous access locking solutions and method of treating the syringe |
| US9072296B2 (en) * | 2009-03-26 | 2015-07-07 | Organic Medical Ventures, L.L.C. | Transdermal venous access locking solutions |
| WO2011019710A2 (en) * | 2009-08-10 | 2011-02-17 | Proviflo, Llc | Catheter lock solutions utilizing tocopheraol and mid-chain fatty acids |
| DE202010006267U1 (de) * | 2010-04-23 | 2010-11-11 | Anbatec Gmbh | Produkt mit einer antimikrobiell wirksamen Oberfläche |
| AU2011326519A1 (en) | 2010-11-09 | 2013-05-30 | Hans-Dietrich Polaschegg | Hemodialysis access system |
| DE102011077393A1 (de) | 2011-06-10 | 2012-12-13 | Johannes Reinmüller | Antiinfektives Mittel |
| US9220814B2 (en) * | 2011-09-29 | 2015-12-29 | Ethicon, Inc. | Broad-spectrum antimicrobial compositions based on combinations of taurolidine and protamine and medical devices containing such compositions |
| US10046137B2 (en) | 2014-02-21 | 2018-08-14 | Avadim Technologies, Inc. | Method for maintenance of urethral catheters |
| US10071052B2 (en) | 2014-11-19 | 2018-09-11 | Avadim Technologies, Inc. | Method for the prevention and treatment of acne |
| US9333289B1 (en) | 2015-01-16 | 2016-05-10 | Plas-Tech Engineering, Inc. | Tamper evident closure container |
| WO2016201269A2 (en) | 2015-06-11 | 2016-12-15 | Proviflo, Llc | Graft-port hemodialysis systems, devices and methods |
| DK3167873T3 (da) | 2015-11-11 | 2019-06-11 | Christian Edwin Weis | Vandig opløsning af kondensationsprodukter af taurinamid og methylenglycol til anvendelse som antiinfektivt middel ved implantationen af anordninger i hjertekirurgien |
| US10744313B2 (en) | 2017-07-27 | 2020-08-18 | University Of Utah Research Foundation | Therapeutic delivery device |
| JP7138702B2 (ja) | 2017-09-22 | 2022-09-16 | ベクトン・ディキンソン・アンド・カンパニー | カテーテルロック溶液としての使用のための4%クエン酸三ナトリウム溶液 |
| CA3143518A1 (en) | 2019-06-12 | 2020-12-17 | Avadim Health Ip, Inc. | Compositions and methods for the antiseptic cleansing and biofilms treatment of mammalian tissue |
| WO2023003792A1 (en) * | 2021-07-19 | 2023-01-26 | Becton, Dickinson And Company | 16% sodium citrate solution for use as an antimicrobial catheter lock solution |
| US11738120B1 (en) | 2022-04-14 | 2023-08-29 | Cormedix Inc. | Synthesis of taurolidine, purity profiles and polymorphs |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1124285A (en) | 1964-10-06 | 1968-08-21 | Geistlich Soehne Ag | Novel perhydro-1,2,4-thiadiazine dioxides-(1,1), their preparation and compositionscontaining them |
| GB1557163A (en) | 1975-06-24 | 1979-12-05 | Geistlich Soehne Ag | Dental care preparations |
| US4107305A (en) | 1975-08-04 | 1978-08-15 | Ed. Geistlich Sohne A.G. Fur Chemische Industrie | Treatment of endotoxaemia |
| US4337251A (en) | 1979-05-09 | 1982-06-29 | Ed. Geistlich Sohne Ag Fur Chemische Industrie | Method of avoiding and removing adhesions |
| CA1190855A (en) | 1980-09-03 | 1985-07-23 | Rolf W. Pfirrmann | Treatment of osteitis |
| GB8328111D0 (en) | 1983-10-20 | 1983-11-23 | Geistlich Soehne Ag | Chemical compounds |
| GB8328073D0 (en) | 1983-10-20 | 1983-11-23 | Geistlich Soehne Ag | Chemical compounds |
| GB8328074D0 (en) | 1983-10-20 | 1983-11-23 | Geistlich Soehne Ag | Chemical compositions |
| GB8408447D0 (en) * | 1984-04-02 | 1984-05-10 | Roussel Lab Ltd | 1,2,4-thiadiazines |
| DE3506288A1 (de) | 1984-09-06 | 1986-03-13 | Johannes 7900 Ulm Reinmüller | Vorrichtung zum einlegen in wunden und wundhoehlen |
| DE3513938A1 (de) | 1985-04-18 | 1986-10-23 | Merck Patent Gmbh, 6100 Darmstadt | Cytostatikahaltiges pharmakadepot |
| GB8514055D0 (en) * | 1985-06-04 | 1985-07-10 | Geistlich Soehne Ag | Chemical substance |
| GB8514052D0 (en) | 1985-06-04 | 1985-07-10 | Geistlich Soehne Ag | Compositions |
| US4587284A (en) | 1985-06-14 | 1986-05-06 | Ed. Geistlich Sohne Ag Fur Chemische Industrie | Absorbent polymer material and its preparation |
| DE3533612A1 (de) | 1985-09-20 | 1987-04-02 | Johannes Reinmueller | Neuartige verwendung von taurolin |
| DE3542972A1 (de) | 1985-12-05 | 1987-06-11 | Merck Patent Gmbh | Pharmakadepot |
| US5210083A (en) * | 1986-07-17 | 1993-05-11 | Ed. Geistlich Sohne A.G. Fur Chemische Industrie | Pharmaceutical compositions |
| GB8813033D0 (en) | 1988-06-02 | 1988-07-06 | Geistlich Soehne Ag | Chemical compound |
| US5573771A (en) | 1988-08-19 | 1996-11-12 | Osteomedical Limited | Medicinal bone mineral products |
| GB9005856D0 (en) | 1990-03-15 | 1990-05-09 | Geistlich Soehne Ag | Compositions |
| DE4137544C2 (de) * | 1991-11-12 | 1998-07-30 | Kramer Axel | Antimikrobielle Wirkstoffkombination auf der Basis von Sauerstoff abspaltenden Verbindungen |
| GB9216155D0 (en) * | 1992-07-30 | 1992-09-09 | Geistlich Soehne Ag | Treatment of dentoalveolar infections |
| US5688516A (en) | 1992-11-12 | 1997-11-18 | Board Of Regents, The University Of Texas System | Non-glycopeptide antimicrobial agents in combination with an anticoagulant, an antithrombotic or a chelating agent, and their uses in, for example, the preparation of medical devices |
| US5362754A (en) | 1992-11-12 | 1994-11-08 | Univ. Of Tx Md Anderson Cancer Center | M-EDTA pharmaceutical preparations and uses thereof |
| EP0698398A1 (de) † | 1994-08-23 | 1996-02-28 | Becton, Dickinson and Company | Blutsammlungsgerät |
| US5603921A (en) | 1995-03-13 | 1997-02-18 | Whalen Biomedical Incorporated | Medicated dental floss and method of preparation |
| GB9626795D0 (en) † | 1996-12-23 | 1997-02-12 | Geistlich Soehne Ag | Combating infection in delivery systems |
| US6166007A (en) * | 1998-07-02 | 2000-12-26 | Sodemann; Klaus | Antimicrobial locks comprising taurinamide derivatives and carboxylic acids and/or salts thereof |
| US6350251B1 (en) * | 2000-01-18 | 2002-02-26 | Biolink Corporation | Biocidal locks |
-
1999
- 1999-05-10 US US09/307,916 patent/US6166007A/en not_active Expired - Lifetime
- 1999-05-28 EP EP99959111.8A patent/EP1089738B2/de not_active Expired - Lifetime
- 1999-05-28 ES ES99959111.8T patent/ES2264274T5/es not_active Expired - Lifetime
- 1999-05-28 AT AT99959111T patent/ATE324896T1/de not_active IP Right Cessation
- 1999-05-28 DE DE69931159.4T patent/DE69931159T3/de not_active Expired - Lifetime
- 1999-05-28 AU AU43196/99A patent/AU4319699A/en not_active Abandoned
- 1999-05-28 WO PCT/US1999/011917 patent/WO2000001391A1/en not_active Ceased
-
2000
- 2000-04-19 US US09/552,198 patent/US6569852B1/en not_active Expired - Lifetime
- 2000-12-20 US US09/741,321 patent/US6423706B2/en not_active Expired - Lifetime
-
2001
- 2001-11-30 US US09/997,970 patent/US6498157B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ES2264274T5 (es) | 2015-12-23 |
| DE69931159D1 (de) | 2006-06-08 |
| US6569852B1 (en) | 2003-05-27 |
| US6423706B2 (en) | 2002-07-23 |
| AU4319699A (en) | 2000-01-24 |
| US20020111346A1 (en) | 2002-08-15 |
| US20010003746A1 (en) | 2001-06-14 |
| US6166007A (en) | 2000-12-26 |
| EP1089738B1 (de) | 2006-05-03 |
| WO2000001391A1 (en) | 2000-01-13 |
| DE69931159T3 (de) | 2016-03-10 |
| EP1089738A4 (de) | 2001-10-31 |
| EP1089738B2 (de) | 2015-10-21 |
| DE69931159T2 (de) | 2007-02-15 |
| US6498157B2 (en) | 2002-12-24 |
| ES2264274T3 (es) | 2006-12-16 |
| EP1089738A1 (de) | 2001-04-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |