ATE325790T1 - Harnstoff-verbindungen, ein verfahren zu deren herstellung und ihre verwendung - Google Patents

Harnstoff-verbindungen, ein verfahren zu deren herstellung und ihre verwendung

Info

Publication number: ATE325790T1
Authority: AT; Austria
Prior art keywords: group; substituted; production; urea compounds; äwherein
Prior art date: 1999-10-05

Application number

AT00964649T

Other languages

English (en)

Inventor

Osamu Kurasawa

Shinichi Imamura

Shohei Hashiguchi

Osamu Nishimura

Naoyuki Kanzaki

Masanori Baba

Original Assignee

Takeda Pharmaceutical

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-10-05

Filing date

2000-10-04

Publication date

2006-06-15

2000-10-04 Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical

2006-06-15 Application granted granted Critical

2006-06-15 Publication of ATE325790T1 publication Critical patent/ATE325790T1/de

Links

XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical class NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 title 1
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
208000030507 AIDS Diseases 0.000 abstract 1
LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical compound OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 abstract 1
102100035875 C-C chemokine receptor type 5 Human genes 0.000 abstract 1
101710149870 C-C chemokine receptor type 5 Proteins 0.000 abstract 1
208000031886 HIV Infections Diseases 0.000 abstract 1
208000037357 HIV infectious disease Diseases 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
125000003277 amino group Chemical group 0.000 abstract 1
125000004397 aminosulfonyl group Chemical group NS(=O)(=O)* 0.000 abstract 1
230000003042 antagnostic effect Effects 0.000 abstract 1
125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
208000033519 human immunodeficiency virus infectious disease Diseases 0.000 abstract 1
125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
230000005764 inhibitory process Effects 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
210000003819 peripheral blood mononuclear cell Anatomy 0.000 abstract 1
230000003389 potentiating effect Effects 0.000 abstract 1
230000002265 prevention Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
- C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Virology (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Molecular Biology (AREA)
Tropical Medicine & Parasitology (AREA)
AIDS & HIV (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

AT00964649T 1999-10-05 2000-10-04 Harnstoff-verbindungen, ein verfahren zu deren herstellung und ihre verwendung ATE325790T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP28449599		1999-10-05

Publications (1)

Publication Number	Publication Date
ATE325790T1 true ATE325790T1 (de)	2006-06-15

Family

ID=17679268

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT00964649T ATE325790T1 (de)	1999-10-05	2000-10-04	Harnstoff-verbindungen, ein verfahren zu deren herstellung und ihre verwendung

Country Status (7)

Country	Link
US (1)	US6787650B1 (de)
EP (1)	EP1219605B1 (de)
AT (1)	ATE325790T1 (de)
AU (1)	AU7556000A (de)
CA (1)	CA2386387A1 (de)
DE (1)	DE60027908T2 (de)
WO (1)	WO2001025199A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1354587A1 (de) *	2000-12-22	2003-10-22	Takeda Chemical Industries, Ltd.	Medizinische zusammensetzungen zur oralen anwendung
FR2821356A1 (fr)	2001-02-23	2002-08-30	Cerep	Nouveaux derives d'arylcarbamates et d'arylurees, preparations et utilisations
GB0108099D0 (en) *	2001-03-30	2001-05-23	Hoffmann La Roche	Aminopiperidine derivatives
EP1500643A4 (de) *	2002-04-03	2007-03-28	Dainippon Sumitomo Pharma Co	Benzamidinderivate
US20050245537A1 (en) *	2002-04-24	2005-11-03	Noboru Tsuchimori	Use of compounds having ccr antagonism
JP2004107298A (ja) *	2002-09-20	2004-04-08	Takeda Chem Ind Ltd	ウレア化合物およびその用途
US7491735B2 (en)	2003-12-11	2009-02-17	Genzyme Corporation	Chemokine receptor binding compounds
US7498346B2 (en)	2003-12-11	2009-03-03	Genzyme Corporation	Chemokine receptor binding compounds
WO2008030853A2 (en) *	2006-09-06	2008-03-13	Incyte Corporation	Combination therapy for human immunodeficiency virus infection
CN113214231B (zh) *	2020-01-21	2022-04-08	瀚远医药有限公司	5ht2a受体拮抗剂及其医疗应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3461120A (en) *	1965-09-27	1969-08-12	Sterling Drug Inc	N-((1-piperidyl)-lower-alkyl)-n-((3-,2-,and 1-indolyl)-lower-alkyl) amines
US4835157A (en) *	1988-03-15	1989-05-30	Ortho Pharmaceutical Corporation	Thieno- and furopyrimidine-2,4-dione piperidine derivatives as serotonin antagonists and alpha adrenergic blocking agents
US5668151A (en) *	1995-06-07	1997-09-16	Bristol-Myers Squibb Company	Dihydropyridine NPY antagonists: piperidine derivatives
JPH09255572A (ja) *	1996-03-26	1997-09-30	Takeda Chem Ind Ltd	ケモカイン受容体拮抗剤
EP1003514A4 (de)	1997-07-25	2000-10-11	Merck & Co Inc	Cyclische amine modulatoren der chemokinrezeptoren
AU3126700A (en) *	1998-12-18	2000-07-03	Du Pont Pharmaceuticals Company	N-ureidoalkyl-piperidines as modulators of chemokine receptor activity

2000
- 2000-10-04 EP EP00964649A patent/EP1219605B1/de not_active Expired - Lifetime
- 2000-10-04 AT AT00964649T patent/ATE325790T1/de not_active IP Right Cessation
- 2000-10-04 DE DE60027908T patent/DE60027908T2/de not_active Expired - Fee Related
- 2000-10-04 US US10/089,961 patent/US6787650B1/en not_active Expired - Fee Related
- 2000-10-04 WO PCT/JP2000/006908 patent/WO2001025199A1/ja not_active Ceased
- 2000-10-04 AU AU75560/00A patent/AU7556000A/en not_active Abandoned
- 2000-10-04 CA CA002386387A patent/CA2386387A1/en not_active Abandoned

Also Published As

Publication number	Publication date
DE60027908D1 (de)	2006-06-14
EP1219605A1 (de)	2002-07-03
WO2001025199A1 (en)	2001-04-12
CA2386387A1 (en)	2001-04-12
US6787650B1 (en)	2004-09-07
DE60027908T2 (de)	2007-05-10
EP1219605A4 (de)	2002-10-30
AU7556000A (en)	2001-05-10
EP1219605B1 (de)	2006-05-10

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Legal Events

Date	Code	Title	Description
2006-11-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties