ATE326475T1 - Cyclische salen metall verbindungen als einfänger von sauerstoffradikalen und verwendbar als antioxidantien bei der behandlung und vorbeugung von krankheiten - Google Patents
Cyclische salen metall verbindungen als einfänger von sauerstoffradikalen und verwendbar als antioxidantien bei der behandlung und vorbeugung von krankheitenInfo
- Publication number
- ATE326475T1 ATE326475T1 AT01987135T AT01987135T ATE326475T1 AT E326475 T1 ATE326475 T1 AT E326475T1 AT 01987135 T AT01987135 T AT 01987135T AT 01987135 T AT01987135 T AT 01987135T AT E326475 T1 ATE326475 T1 AT E326475T1
- Authority
- AT
- Austria
- Prior art keywords
- metal compounds
- cyclic salen
- caughters
- antioxidants
- diseases
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
- C07F13/005—Compounds without a metal-carbon linkage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Toxicology (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Biochemistry (AREA)
- Psychology (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/724,776 US6589948B1 (en) | 2000-11-28 | 2000-11-28 | Cyclic salen-metal compounds: reactive oxygen species scavengers useful as antioxidants in the treatment and prevention of diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE326475T1 true ATE326475T1 (de) | 2006-06-15 |
Family
ID=24911859
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01987135T ATE326475T1 (de) | 2000-11-28 | 2001-11-28 | Cyclische salen metall verbindungen als einfänger von sauerstoffradikalen und verwendbar als antioxidantien bei der behandlung und vorbeugung von krankheiten |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US6589948B1 (de) |
| EP (2) | EP1349864B1 (de) |
| JP (1) | JP4316878B2 (de) |
| CN (1) | CN1318435C (de) |
| AT (1) | ATE326475T1 (de) |
| AU (2) | AU3938102A (de) |
| CA (1) | CA2430133C (de) |
| DE (1) | DE60119784T2 (de) |
| RU (1) | RU2003119169A (de) |
| WO (1) | WO2002044187A2 (de) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7582786B2 (en) * | 1992-12-07 | 2009-09-01 | Eukarion Inc. | Synthetic catalytic free radical scavengers useful as antioxidants for prevention and therapy of disease |
| US6589948B1 (en) * | 2000-11-28 | 2003-07-08 | Eukarion, Inc. | Cyclic salen-metal compounds: reactive oxygen species scavengers useful as antioxidants in the treatment and prevention of diseases |
| US20030087455A1 (en) * | 2001-11-07 | 2003-05-08 | Eggers Mitchell D | Sample carrier system |
| US7700074B2 (en) * | 2002-02-07 | 2010-04-20 | Pettegrew Jay W | Method and system for diagnosis of neuropsychiatric disorders including chronic alcoholism |
| US7407778B2 (en) * | 2002-02-07 | 2008-08-05 | Pettegrew Jay W | Compounds, compositions and methods for treating neuropsychiatric disorders |
| DE10208252A1 (de) * | 2002-02-26 | 2003-09-04 | Celanese Ventures Gmbh | Konvalent fixierte Non-Metallocene, Verfahren zur Herstellung von diesen und deren Verwendung zur Polymerisation von Olefinen |
| US7585514B2 (en) * | 2002-06-11 | 2009-09-08 | L'oreal | Administration of agents mimicking DOPAchrome tautomerase (TRP-2) activity for protecting hair follicle melanocytes |
| AU2003247144B2 (en) * | 2002-08-02 | 2007-11-29 | Mor Research Applications Ltd. | Treatment of multiple sclerosis with brain targeted anti oxidant compounds |
| EP1641806B1 (de) * | 2003-05-29 | 2009-07-29 | Jay W. Pettegrew | Glycerophosphocholin und derivate davon zur medizinischen abbildung von neuropsychiatrischen erkrankungen |
| US20060257842A1 (en) * | 2003-05-29 | 2006-11-16 | Pettegrew Jay W | Cryopreservation media and molecules |
| US7299082B2 (en) | 2003-10-31 | 2007-11-20 | Abbott Diabetes Care, Inc. | Method of calibrating an analyte-measurement device, and associated methods, devices and systems |
| US20060160748A1 (en) * | 2003-11-25 | 2006-07-20 | Shey-Shing Sheu | Compounds for delivering amino acids or peptides with antioxidant activity into mitochondria and use thereof |
| US7699964B2 (en) | 2004-02-09 | 2010-04-20 | Abbott Diabetes Care Inc. | Membrane suitable for use in an analyte sensor, analyte sensor, and associated method |
| US8165651B2 (en) | 2004-02-09 | 2012-04-24 | Abbott Diabetes Care Inc. | Analyte sensor, and associated system and method employing a catalytic agent |
| JP2008500347A (ja) * | 2004-05-24 | 2008-01-10 | ニュー・ヨーク・ユニヴァーシティー | 高血糖症による血糖の急激な増加及び/又は急激な遊離脂肪酸流動の増加の病理学的影響の治療方法又は予防方法 |
| FR2875500A1 (fr) * | 2004-09-21 | 2006-03-24 | Centre Nat Rech Scient | Complexe chiraux macrocycliques utilisables comme catalyseurs |
| US8455437B2 (en) * | 2005-02-04 | 2013-06-04 | The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services | Method to predict and prevent oxygen-induced inflammatory tissue injury |
| US7885698B2 (en) | 2006-02-28 | 2011-02-08 | Abbott Diabetes Care Inc. | Method and system for providing continuous calibration of implantable analyte sensors |
| EP2345974B1 (de) * | 2006-06-28 | 2014-08-06 | IHI Corporation | Magnetisch führbare Verbindung |
| US8252780B2 (en) * | 2006-12-01 | 2012-08-28 | Women & Infants' Hospital | Organometallic complexes as therapeutic agents |
| US20090169484A1 (en) | 2007-12-28 | 2009-07-02 | Ihi Corporation | Iron-salen complex |
| US9907976B2 (en) | 2011-07-08 | 2018-03-06 | Immunolight, Llc | Phosphors and scintillators for light stimulation within a medium |
| CA2906990A1 (en) * | 2008-04-04 | 2009-10-08 | Duke University | Non-invasive systems and methods for in-situ photobiomodulation |
| US20090286968A1 (en) | 2008-04-25 | 2009-11-19 | Auburn University | 2-Quinoxalinol Salen Compounds and Uses Thereof |
| CA2724023C (en) * | 2008-05-13 | 2014-02-18 | Genmedica Therapeutics Sl | Salicylate conjugates useful for treating metabolic disorders |
| US20100209957A1 (en) * | 2008-06-20 | 2010-08-19 | Genvault Corporation | Biosample storage devices and methods of use thereof |
| US8198322B2 (en) * | 2008-06-25 | 2012-06-12 | Board Of Regents, The University Of Texas System | Apoptotic and anti-tumor activities of metallo-salens |
| WO2010031007A2 (en) | 2008-09-12 | 2010-03-18 | Genvault Corporation | Matrices and media for storage and stabilization of biomolecules |
| US10098857B2 (en) | 2008-10-10 | 2018-10-16 | The Board Of Trustees Of The Leland Stanford Junior University | Topical and transdermal delivery of HIF-1 modulators to prevent and treat chronic wounds |
| CN104800195A (zh) | 2008-11-20 | 2015-07-29 | 株式会社Ihi | 自磁性金属salen络合物 |
| KR101050273B1 (ko) | 2008-11-21 | 2011-07-19 | 세종대학교산학협력단 | 살렌 전이금속 착화합물, 및 그 제조 방법 |
| US20100239552A1 (en) * | 2009-03-16 | 2010-09-23 | Genmedica Therapeutics Sl | Combination Therapies for Treating Metabolic Disorders |
| JP2012520342A (ja) * | 2009-03-16 | 2012-09-06 | ジェンメディカ・セラピューティックス・ソシエダッド・リミターダ | 代謝障害を処置するのに有用な抗炎症剤および抗酸化剤のコンジュゲート |
| US8466197B2 (en) | 2010-12-14 | 2013-06-18 | Genmedica Therapeutics Sl | Thiocarbonates as anti-inflammatory and antioxidant compounds useful for treating metabolic disorders |
| EP2760874A4 (de) * | 2011-09-26 | 2015-04-08 | Galera Therapeutics Llc | Verfahren zur behandlung von erkrankungen |
| EP2580967A1 (de) * | 2011-10-11 | 2013-04-17 | Nestec S.A. | Beschleunigung der Muskelerholung nach immobilisierungsinduzierter Muskelatrophie |
| WO2015057964A2 (en) * | 2013-10-16 | 2015-04-23 | The Board Of Regents Of The University Of Texas System | Modulation of mrtf-a activity in pathologic fibrosis and wound healing |
| AU2014374361B9 (en) | 2013-12-31 | 2019-07-04 | Abbott Diabetes Care Inc. | Self-powered analyte sensor and devices using the same |
| JP6977979B2 (ja) * | 2015-06-09 | 2021-12-08 | 国立大学法人大阪大学 | 神経損傷治療又は予防用医薬 |
| AU2018226872A1 (en) | 2017-03-03 | 2019-09-05 | Macregen, Inc. | Treatment of age-related macular degeneration and other eye diseases with one or more therapeutic agents |
| EP3642214A2 (de) | 2017-06-19 | 2020-04-29 | Gangadhara Ganapati | Nicotinamid-ribosid-derivate und deren verwendungen |
| JP2020528082A (ja) | 2017-07-17 | 2020-09-17 | ロイズマン,キース | 加齢黄斑変性と他の眼疾患の治療用の細胞透過性ペプチドを使用する治療薬の局所送達 |
| WO2019055490A1 (en) | 2017-09-14 | 2019-03-21 | The Board Of Trustees Of The Leland Stanford Junior University | PACKAGING OF IRRADIED FABRIC FOR FAT GREETING RETENTION |
| US11911504B2 (en) | 2018-02-02 | 2024-02-27 | Galen Therapeutics Llc | Apparatus and method for protecting neurons and reducing inflammation and scarring |
| WO2020094789A1 (en) | 2018-11-08 | 2020-05-14 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and compositions for preventing and/or treating age-related hearing loss |
| EP3897666A2 (de) | 2018-12-17 | 2021-10-27 | Mitopower LLC | Nicotinylribosidverbindungen und ihre verwendungen |
| WO2020237117A1 (en) * | 2019-05-23 | 2020-11-26 | Christopher Duke | Compounds that react with reactive species to control byproducts |
| US20200397807A1 (en) | 2019-06-18 | 2020-12-24 | MitoPower, LLC | Nicotinyl riboside compounds and their uses |
| CN115138385B (zh) * | 2022-05-20 | 2023-03-17 | 四川大学 | 一种仿金属酶生物催化材料及其制备方法和用途 |
| CN115869465B (zh) * | 2022-12-12 | 2023-09-01 | 之江实验室 | 一种天然蛋白光刻胶和活性氧清除细胞支架的制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5106841A (en) | 1986-05-13 | 1992-04-21 | Chai-Tech Corporation | Antiviral compositions and method for their use |
| US5223538A (en) | 1987-03-31 | 1993-06-29 | Duke University | Superoxide dismutase mimic |
| DE69026793D1 (de) * | 1989-11-16 | 1996-06-05 | Mitsui Petrochemical Ind | Behälter mit einem Aufhängegriff und Verfahren zu seiner Herstellung |
| DK0643626T3 (da) | 1991-08-26 | 2002-05-13 | Res Corp Technologies Inc | Fremgangsmåde til fremstilling af epoxychromaner med en chiral katalysator |
| US5696109A (en) | 1992-12-07 | 1997-12-09 | Eukarion, Inc. | Synthetic catalytic free radical scavengers useful as antioxidants for prevention and therapy of disease |
| US5834509A (en) | 1992-12-07 | 1998-11-10 | Eukarion, Inc. | Synthetic catalytic free radical scavengers useful as antioxidants for prevention and therapy of disease |
| US5403834A (en) | 1992-12-07 | 1995-04-04 | Eukarion, Inc. | Synthetic catalytic free radical scavengers useful as antioxidants for prevention and therapy of disease |
| US6589948B1 (en) * | 2000-11-28 | 2003-07-08 | Eukarion, Inc. | Cyclic salen-metal compounds: reactive oxygen species scavengers useful as antioxidants in the treatment and prevention of diseases |
| US7006677B2 (en) * | 2002-04-15 | 2006-02-28 | General Electric Company | Semi-automatic segmentation algorithm for pet oncology images |
-
2000
- 2000-11-28 US US09/724,776 patent/US6589948B1/en not_active Expired - Fee Related
-
2001
- 2001-11-28 JP JP2002546557A patent/JP4316878B2/ja not_active Expired - Fee Related
- 2001-11-28 DE DE60119784T patent/DE60119784T2/de not_active Expired - Lifetime
- 2001-11-28 US US10/432,752 patent/US7122537B2/en not_active Expired - Fee Related
- 2001-11-28 EP EP01987135A patent/EP1349864B1/de not_active Expired - Lifetime
- 2001-11-28 AU AU3938102A patent/AU3938102A/xx active Pending
- 2001-11-28 CA CA2430133A patent/CA2430133C/en not_active Expired - Fee Related
- 2001-11-28 AT AT01987135T patent/ATE326475T1/de not_active IP Right Cessation
- 2001-11-28 RU RU2003119169/04A patent/RU2003119169A/ru not_active Application Discontinuation
- 2001-11-28 CN CNB018216625A patent/CN1318435C/zh not_active Expired - Fee Related
- 2001-11-28 AU AU2002239381A patent/AU2002239381B2/en not_active Ceased
- 2001-11-28 WO PCT/US2001/044686 patent/WO2002044187A2/en not_active Ceased
- 2001-11-28 EP EP06009729A patent/EP1688425A3/de not_active Withdrawn
-
2006
- 2006-09-15 US US11/521,882 patent/US20070123503A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU3938102A (en) | 2002-06-11 |
| DE60119784D1 (de) | 2006-06-22 |
| JP4316878B2 (ja) | 2009-08-19 |
| AU2002239381B2 (en) | 2007-12-13 |
| CN1318435C (zh) | 2007-05-30 |
| EP1688425A2 (de) | 2006-08-09 |
| JP2004514724A (ja) | 2004-05-20 |
| US20040059107A1 (en) | 2004-03-25 |
| US20070123503A1 (en) | 2007-05-31 |
| RU2003119169A (ru) | 2004-12-10 |
| CN1636007A (zh) | 2005-07-06 |
| WO2002044187A2 (en) | 2002-06-06 |
| EP1349864A2 (de) | 2003-10-08 |
| CA2430133A1 (en) | 2002-06-06 |
| EP1349864B1 (de) | 2006-05-17 |
| US6589948B1 (en) | 2003-07-08 |
| CA2430133C (en) | 2013-01-15 |
| DE60119784T2 (de) | 2007-01-04 |
| EP1688425A3 (de) | 2006-08-30 |
| WO2002044187A3 (en) | 2002-09-12 |
| US7122537B2 (en) | 2006-10-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |