ATE32661T1 - Verfahren zur reinigung von modulatoren des immunsystems. - Google Patents

Verfahren zur reinigung von modulatoren des immunsystems.

Info

Publication number
ATE32661T1
ATE32661T1 AT83111442T AT83111442T ATE32661T1 AT E32661 T1 ATE32661 T1 AT E32661T1 AT 83111442 T AT83111442 T AT 83111442T AT 83111442 T AT83111442 T AT 83111442T AT E32661 T1 ATE32661 T1 AT E32661T1
Authority
AT
Austria
Prior art keywords
modulators
effects
amplifiers
suppressor
human
Prior art date
Application number
AT83111442T
Other languages
English (en)
Inventor
Arthur A Gottlieb
Original Assignee
Arthur A Gottlieb
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arthur A Gottlieb filed Critical Arthur A Gottlieb
Application granted granted Critical
Publication of ATE32661T1 publication Critical patent/ATE32661T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/05—Immunological preparations stimulating the reticulo-endothelial system, e.g. against cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/15—Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cells; Myeloid precursor cells; Antigen-presenting cells, e.g. dendritic cells
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/24—Dialysis ; Membrane extraction
    • B01D61/243—Dialysis
    • B01D61/244—Dialysis comprising multiple dialysis steps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/32—Bonded phase chromatography
    • B01D15/325—Reversed phase
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2311/00—Details relating to membrane separation process operations and control
    • B01D2311/06—Specific process operations in the permeate stream
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2311/00—Details relating to membrane separation process operations and control
    • B01D2311/26—Further operations combined with membrane separation processes
    • B01D2311/2649—Filtration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2311/00—Details relating to membrane separation process operations and control
    • B01D2311/26—Further operations combined with membrane separation processes
    • B01D2311/2697—Chromatography

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Water Supply & Treatment (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Amplifiers (AREA)
  • Purification Treatments By Anaerobic Or Anaerobic And Aerobic Bacteria Or Animals (AREA)
AT83111442T 1982-11-15 1983-11-15 Verfahren zur reinigung von modulatoren des immunsystems. ATE32661T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/441,432 US4468379A (en) 1982-05-06 1982-11-15 Leukocyte extracts for affecting the immune system
EP83111442A EP0109089B1 (de) 1982-11-15 1983-11-15 Verfahren zur Reinigung von Modulatoren des Immunsystems

Publications (1)

Publication Number Publication Date
ATE32661T1 true ATE32661T1 (de) 1988-03-15

Family

ID=23752845

Family Applications (1)

Application Number Title Priority Date Filing Date
AT83111442T ATE32661T1 (de) 1982-11-15 1983-11-15 Verfahren zur reinigung von modulatoren des immunsystems.

Country Status (4)

Country Link
US (1) US4468379A (de)
EP (1) EP0109089B1 (de)
AT (1) ATE32661T1 (de)
DE (1) DE3375759D1 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4988676A (en) * 1984-05-11 1991-01-29 Sloan-Kettering Institute For Cancer Research Cellular proliferation T cell suppressor factor
US4618494A (en) * 1984-07-20 1986-10-21 Immunology Development Corporation Human Immune Factors and processes for their production and use
US4616079A (en) * 1984-08-24 1986-10-07 Imreg, Inc. Immunoamplifiers and processes for the extraction thereof
US5100663A (en) * 1984-08-24 1992-03-31 Imreg, Inc. Tyr-Gly compositions useful in increasing immune response
US5093321A (en) * 1984-08-24 1992-03-03 Imreg, Inc. Dialysates for treating aids and arc and for otherwise increasing immune response
EP0212285A1 (de) * 1985-07-29 1987-03-04 Arthur A. Gottlieb Herleitung und Verwendung ausgewählter Genprodukte
US5643565A (en) * 1985-09-20 1997-07-01 Chiron Corporation Human IL-2 as a vaccine adjuvant
US4689224A (en) * 1985-10-07 1987-08-25 Neogen Corporation Method for administering vaccines containing equine leukokines and compositions therefor
CA1286989C (en) 1985-12-26 1991-07-30 A. Arthur Gottlieb Immunoamplifiers and related compositions
US4778750A (en) * 1986-02-19 1988-10-18 Imreg, Inc. Diagnostic methods for immune function
US4710380A (en) * 1986-04-04 1987-12-01 Imreg, Inc. Treatment of autoimmune disorders with immunoamplifiers
EP0247538A3 (de) * 1986-05-28 1989-08-30 Imreg, Inc. Immunosuppressivum und Verfahren zu seiner Extraktion
US4920097A (en) * 1986-05-28 1990-04-24 Imreg, Inc. Immunosuppressor and method of extraction thereof from leukocytes
GB8614733D0 (en) * 1986-06-17 1986-07-23 Lefesvre A Aids treatment
US4874608A (en) * 1987-04-27 1989-10-17 Imreg, Inc. Therapeutic method for treating malignancies
US5316775A (en) * 1988-08-04 1994-05-31 Kremers-Urban Company Method of treating hepatitis B infection
US5284664A (en) * 1988-08-04 1994-02-08 Kremers-Urban Company Method of treating the symptoms of Alzheimer's disease
US5334395A (en) * 1988-08-04 1994-08-02 Kremers-Urban Company Method of treating an epstein-barr viral infection
US5055296A (en) * 1988-08-04 1991-10-08 Wagle Sudhakar S Method of treating chronic fatigue syndrome
US5013546A (en) * 1988-08-23 1991-05-07 Imreg, Inc. Methods for modulating antibody production in treating patients with AIDS, ARC and other diseases
IL96477A0 (en) * 1989-12-01 1991-08-16 Amgen Inc Megakaryocyte production
JPH05508847A (ja) * 1990-07-02 1993-12-09 ナシヨナル・ジユーイツシユ・センター・フオー・イミユノロジー・アンド・レスピラトリー・メデイシン 伝達因子および使用方法
AU8107191A (en) * 1990-07-02 1992-01-23 National Jewish Center For Immunology And Respiratory Medicine Process for obtaining pure peptide transfer factor, transfer factor thus obtained and uses thereof
CA2149146A1 (en) * 1992-07-21 1994-02-03 Dmitry Borislavovich Shorokh Biologically active agent having immuno-modulating properties, method for its obtaining and pharmaceutical preparation based on it
US5883224A (en) * 1996-04-19 1999-03-16 Cytokine Sciences, Inc. Characterization of transfer factors and methods of use
US6783987B2 (en) 1999-12-09 2004-08-31 Tsukasa Matsumoto Method for obtaining components from cultured leucocyte
MXPA02002171A (es) * 2002-02-28 2002-12-09 Antonio Calzada Nova Luis Extracto de leucocitos dializado en la elaboracion de un farmaco para el tratamiento de enfermedades infecciosas en animales.
US7632818B2 (en) * 2003-03-20 2009-12-15 Gottlieb Marise S Method for treating conditions associated with the Metabolic Syndrome (Syndrome X)
CN100333787C (zh) * 2004-08-17 2007-08-29 麦瑞斯·高特莱布 Yg及ygg作为维持和改善免疫反应的药物中的应用
DE102004047262A1 (de) * 2004-09-24 2006-04-06 Ipss International Pharmaceutical Strategies & Solutions Pharmazeutisches Mittel umfassend Blutprodukte und deren Verwendung als Injektions- oder Infusionsmittel zur Prophylaxe und Behandlung von Defekten des Immunsystems beim Menschen
US20060067942A1 (en) * 2004-09-24 2006-03-30 Salama Zoser B Pharmaceutical agent comprising amino acids, peptides, proteins and/or fractions and fragments thereof and the use of same in the prophylaxis and treatment of immune system deficiency in humans and animals
EP1640012A1 (de) * 2004-09-24 2006-03-29 Salama, Zoser B. nat.rer.Dr. Pharmazeutisches Mittel enthaltend Blutbestandteile 10 kDa und deren Verwendung zur Prophylaxe und Behandlung von Defekten des Immunsystems
CZ299296B6 (cs) * 2006-06-13 2008-06-11 Sevapharma A.S. Lécivo transfer faktor - zpusob výroby a použití
GB2444232A (en) 2006-11-30 2008-06-04 Ethicon Inc Wound dressing compositions comprising cell lysates
MX338863B (es) * 2011-12-16 2016-05-01 Inst Politecnico Nacional Metodo de obtencion de extracto dializable de leucocitos.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3991182A (en) * 1971-10-19 1976-11-09 The Regents Of The University Of California Transfer factor
US4132776A (en) * 1978-02-15 1979-01-02 University Patents, Inc. Delivery of immunologically active components of transfer factor
US4180627A (en) * 1978-08-17 1979-12-25 The United States Of America As Represented By The Secretary Of Agriculture Process for in vivo transfer of cell-mediated immunity in mammals with alcoholic precipitates of Bovine Transfer factor
JPS56500015A (de) * 1978-10-25 1981-01-08
IE53572B1 (en) * 1980-05-14 1988-12-21 Arthur Gottlieb A Modulators of the immune system

Also Published As

Publication number Publication date
EP0109089A1 (de) 1984-05-23
EP0109089B1 (de) 1988-03-02
DE3375759D1 (en) 1988-04-07
US4468379A (en) 1984-08-28

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee