ATE327248T1 - Verfahren zur herstellung von mit trunkamid-a verwandten verbindungen - Google Patents
Verfahren zur herstellung von mit trunkamid-a verwandten verbindungenInfo
- Publication number
- ATE327248T1 ATE327248T1 AT02720151T AT02720151T ATE327248T1 AT E327248 T1 ATE327248 T1 AT E327248T1 AT 02720151 T AT02720151 T AT 02720151T AT 02720151 T AT02720151 T AT 02720151T AT E327248 T1 ATE327248 T1 AT E327248T1
- Authority
- AT
- Austria
- Prior art keywords
- trunkamid
- producing
- related compounds
- cycloheptapeptides
- trunkamide
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000002243 precursor Substances 0.000 abstract 1
- 238000010532 solid phase synthesis reaction Methods 0.000 abstract 1
- UTERRJKSLJLXTA-LVPVHDLMSA-N trunkamide Chemical compound C([C@H]1C=2SC[C@H](N=2)C(=O)N[C@H](C(=O)N[C@@H](COC(C)(C)C=C)C(=O)N[C@H](C(N[C@@H](C)C(=O)N2CCC[C@H]2C(=O)N1)=O)[C@@H](C)CC)[C@@H](C)OC(C)(C)C=C)C1=CC=CC=C1 UTERRJKSLJLXTA-LVPVHDLMSA-N 0.000 abstract 1
- UTERRJKSLJLXTA-UHFFFAOYSA-N trunkamide A Natural products N1C(=O)C2CCCN2C(=O)C(C)NC(=O)C(C(C)CC)NC(=O)C(COC(C)(C)C=C)NC(=O)C(C(C)OC(C)(C)C=C)NC(=O)C(N=2)CSC=2C1CC1=CC=CC=C1 UTERRJKSLJLXTA-UHFFFAOYSA-N 0.000 abstract 1
- 108010050721 trunkamide A Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0108234.6A GB0108234D0 (en) | 2001-04-02 | 2001-04-02 | Process for producing trunkamide A compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE327248T1 true ATE327248T1 (de) | 2006-06-15 |
Family
ID=9912086
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02720151T ATE327248T1 (de) | 2001-04-02 | 2002-04-02 | Verfahren zur herstellung von mit trunkamid-a verwandten verbindungen |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US7531506B2 (de) |
| EP (1) | EP1373305B1 (de) |
| JP (1) | JP4249488B2 (de) |
| AT (1) | ATE327248T1 (de) |
| AU (1) | AU2002251221B8 (de) |
| BR (1) | BR0208628A (de) |
| CA (1) | CA2443207A1 (de) |
| DE (1) | DE60211671T2 (de) |
| ES (1) | ES2265494T3 (de) |
| GB (1) | GB0108234D0 (de) |
| IL (1) | IL158145A0 (de) |
| MX (1) | MXPA03009008A (de) |
| NZ (1) | NZ528532A (de) |
| WO (1) | WO2002081506A1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070264023A1 (en) * | 2006-04-26 | 2007-11-15 | Virgin Islands Microsystems, Inc. | Free space interchip communications |
| PT2183273T (pt) | 2007-08-17 | 2017-05-22 | Novartis Ag | Depsipéptidos cíclicos |
| US8614289B2 (en) * | 2011-04-20 | 2013-12-24 | Novartis Ag | Processes for the manufacture of macrocyclic depsipeptides and new intermediates |
| US8680054B2 (en) | 2011-04-20 | 2014-03-25 | Novartis Ag | Suspension type topical formulations comprising cyclic depsipeptide |
| US9067978B2 (en) | 2012-10-09 | 2015-06-30 | Novartis Ag | Solution phase processes for the manufacture of macrocyclic depsipeptides and new intermediates |
| US8987413B2 (en) | 2012-10-09 | 2015-03-24 | Novartis Ag | Aldehyde acetal based processes for the manufacture of macrocyclic depsipeptides and new intermediates |
| KR102491180B1 (ko) | 2017-04-27 | 2023-01-20 | 파르마 마르 에스.에이. | 항종양 화합물 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9608010D0 (en) * | 1996-04-18 | 1996-06-19 | Pharma Mar Sa | Trunkamide A |
| AU3301997A (en) | 1996-06-10 | 1998-01-07 | Board Of Trustees Of The Leland Stanford Junior University | Total synthesis of bacitracin polypetides |
-
2001
- 2001-04-02 GB GBGB0108234.6A patent/GB0108234D0/en not_active Ceased
-
2002
- 2002-04-02 MX MXPA03009008A patent/MXPA03009008A/es active IP Right Grant
- 2002-04-02 EP EP02720151A patent/EP1373305B1/de not_active Expired - Lifetime
- 2002-04-02 IL IL15814502A patent/IL158145A0/xx unknown
- 2002-04-02 CA CA002443207A patent/CA2443207A1/en not_active Abandoned
- 2002-04-02 US US10/473,096 patent/US7531506B2/en not_active Expired - Fee Related
- 2002-04-02 AU AU2002251221A patent/AU2002251221B8/en not_active Ceased
- 2002-04-02 NZ NZ528532A patent/NZ528532A/en unknown
- 2002-04-02 ES ES02720151T patent/ES2265494T3/es not_active Expired - Lifetime
- 2002-04-02 JP JP2002579492A patent/JP4249488B2/ja not_active Expired - Fee Related
- 2002-04-02 BR BR0208628-0A patent/BR0208628A/pt not_active Application Discontinuation
- 2002-04-02 WO PCT/GB2002/001527 patent/WO2002081506A1/en not_active Ceased
- 2002-04-02 DE DE60211671T patent/DE60211671T2/de not_active Expired - Fee Related
- 2002-04-02 AT AT02720151T patent/ATE327248T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1373305B1 (de) | 2006-05-24 |
| ES2265494T3 (es) | 2007-02-16 |
| JP4249488B2 (ja) | 2009-04-02 |
| BR0208628A (pt) | 2004-08-10 |
| US7531506B2 (en) | 2009-05-12 |
| CA2443207A1 (en) | 2002-10-17 |
| AU2002251221B2 (en) | 2007-11-08 |
| NZ528532A (en) | 2005-03-24 |
| WO2002081506A8 (en) | 2003-12-11 |
| US20050014684A1 (en) | 2005-01-20 |
| EP1373305A1 (de) | 2004-01-02 |
| JP2004534746A (ja) | 2004-11-18 |
| IL158145A0 (en) | 2004-03-28 |
| DE60211671T2 (de) | 2007-05-10 |
| DE60211671D1 (de) | 2006-06-29 |
| WO2002081506A1 (en) | 2002-10-17 |
| GB0108234D0 (en) | 2001-05-23 |
| MXPA03009008A (es) | 2004-02-17 |
| AU2002251221B8 (en) | 2008-05-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |