ATE327321T1 - Zyklische depsipeptid-synthasen, deren gene und system zur massenproduktion von zyklischen depsipeptiden - Google Patents
Zyklische depsipeptid-synthasen, deren gene und system zur massenproduktion von zyklischen depsipeptidenInfo
- Publication number
- ATE327321T1 ATE327321T1 AT00957009T AT00957009T ATE327321T1 AT E327321 T1 ATE327321 T1 AT E327321T1 AT 00957009 T AT00957009 T AT 00957009T AT 00957009 T AT00957009 T AT 00957009T AT E327321 T1 ATE327321 T1 AT E327321T1
- Authority
- AT
- Austria
- Prior art keywords
- cyclic depsipeptide
- cyclic
- present
- mass production
- synthetase
- Prior art date
Links
- 108010002156 Depsipeptides Proteins 0.000 title abstract 10
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 108090000364 Ligases Proteins 0.000 abstract 6
- 102000003960 Ligases Human genes 0.000 abstract 5
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 3
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 238000012217 deletion Methods 0.000 abstract 1
- 230000037430 deletion Effects 0.000 abstract 1
- 238000003780 insertion Methods 0.000 abstract 1
- 230000037431 insertion Effects 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP25304099 | 1999-09-07 | ||
| JP2000104291 | 2000-04-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE327321T1 true ATE327321T1 (de) | 2006-06-15 |
Family
ID=26541010
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00957009T ATE327321T1 (de) | 1999-09-07 | 2000-09-07 | Zyklische depsipeptid-synthasen, deren gene und system zur massenproduktion von zyklischen depsipeptiden |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7285404B1 (de) |
| EP (1) | EP1215281B1 (de) |
| JP (1) | JP3961289B2 (de) |
| KR (1) | KR100702728B1 (de) |
| CN (1) | CN1183248C (de) |
| AT (1) | ATE327321T1 (de) |
| AU (1) | AU784466B2 (de) |
| CA (1) | CA2384122C (de) |
| DE (1) | DE60028217T2 (de) |
| NO (1) | NO330902B1 (de) |
| NZ (1) | NZ517588A (de) |
| WO (1) | WO2001018179A1 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE354650T1 (de) | 2000-04-26 | 2007-03-15 | Meiji Seika Kaisha | Neuartige (r)-2-hydroxy-3-phenylpropionat (d- phenyllaktat) dehydrogenase und für diese kodierendes gen |
| US7326546B2 (en) * | 2005-03-10 | 2008-02-05 | Ajinomoto Co., Inc. | Purine-derived substance-producing bacterium and a method for producing purine-derived substance |
| EP1924699A4 (de) * | 2005-08-26 | 2009-11-11 | Aureogen Biosciences | Aureobasidin-a-synthetase |
| BR112012019458B8 (pt) | 2010-01-26 | 2022-08-02 | Mmag Co Ltd | construção de ácidos nucleicos, transformante, e métodos para produzir piripiropenos |
| CA2878644C (en) | 2012-07-09 | 2023-10-03 | Meiji Seika Pharma Co., Ltd. | Uk-2 biosynthetic genes and method for improving uk-2 productivity using the same |
| CA2943240C (en) * | 2014-03-20 | 2021-06-29 | Technische Universitat Berlin | Method for obtaining microbial secondary metabolites or derivatives thereof by heterologous expression of at least one synthetase of said secondary metabolites in filamentous fungi |
| GB201421850D0 (en) * | 2014-12-09 | 2015-01-21 | Bactevo Ltd | Method for screening for bioactive natural products |
| CN106749569B (zh) * | 2017-03-03 | 2021-10-15 | 重庆乾泰生物医药有限公司 | 一种pf1022a的分离纯化方法 |
| WO2018166899A1 (en) | 2017-03-14 | 2018-09-20 | Acidophil Ltd | Methods for production of pf1022a derivatives |
| CN113046332B (zh) * | 2021-03-29 | 2023-08-01 | 华东理工大学 | 一类二倍半萜骨架化合物及其合成基因及制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO176766C (no) | 1989-02-07 | 1995-05-24 | Meiji Seika Kaisha | Fremgangsmåte for fremstilling av en forbindelse med anthelmintaktivitet |
| EP0578616A3 (en) * | 1992-07-09 | 1994-06-01 | Sandoz Ltd | Cylosporin synthetase |
| JP3910634B2 (ja) * | 1995-06-22 | 2007-04-25 | 明治製菓株式会社 | Ｐｆ１０２２物質を産生する形質転換体、及び糸状菌綱に属する菌の形質転換方法 |
| US6057491A (en) * | 1997-05-29 | 2000-05-02 | Borad Of Regents For University Of Oklahoma | Protein having insecticidal activities and method of use |
-
2000
- 2000-09-07 AU AU68741/00A patent/AU784466B2/en not_active Ceased
- 2000-09-07 WO PCT/JP2000/006103 patent/WO2001018179A1/ja not_active Ceased
- 2000-09-07 NZ NZ517588A patent/NZ517588A/en not_active IP Right Cessation
- 2000-09-07 KR KR1020027002704A patent/KR100702728B1/ko not_active Expired - Fee Related
- 2000-09-07 CA CA2384122A patent/CA2384122C/en not_active Expired - Fee Related
- 2000-09-07 DE DE60028217T patent/DE60028217T2/de not_active Expired - Lifetime
- 2000-09-07 JP JP2001522391A patent/JP3961289B2/ja not_active Expired - Fee Related
- 2000-09-07 US US10/070,387 patent/US7285404B1/en not_active Expired - Fee Related
- 2000-09-07 EP EP00957009A patent/EP1215281B1/de not_active Expired - Lifetime
- 2000-09-07 CN CNB008153019A patent/CN1183248C/zh not_active Expired - Fee Related
- 2000-09-07 AT AT00957009T patent/ATE327321T1/de not_active IP Right Cessation
-
2002
- 2002-03-06 NO NO20021100A patent/NO330902B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1215281B1 (de) | 2006-05-24 |
| CN1183248C (zh) | 2005-01-05 |
| CA2384122C (en) | 2010-05-04 |
| JP3961289B2 (ja) | 2007-08-22 |
| EP1215281A4 (de) | 2003-07-02 |
| NO20021100L (no) | 2002-05-07 |
| EP1215281A1 (de) | 2002-06-19 |
| NO20021100D0 (no) | 2002-03-06 |
| KR100702728B1 (ko) | 2007-04-03 |
| NO330902B1 (no) | 2011-08-15 |
| CN1387566A (zh) | 2002-12-25 |
| US7285404B1 (en) | 2007-10-23 |
| DE60028217D1 (de) | 2006-06-29 |
| CA2384122A1 (en) | 2001-03-15 |
| NZ517588A (en) | 2005-01-28 |
| WO2001018179A1 (fr) | 2001-03-15 |
| AU784466B2 (en) | 2006-04-06 |
| AU6874100A (en) | 2001-04-10 |
| DE60028217T2 (de) | 2007-04-26 |
| KR20020029767A (ko) | 2002-04-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2177475T1 (es) | Genes de corynebacterium glutamicum que codifican proteinas de una ruta metabolica. | |
| DK1011717T3 (da) | Arginin-deiminase afledt af mycoplasma-arthritidis og polymere konjugater indeholdende dette | |
| AU7891498A (en) | Flower organ-specific gene and its promoter sequence | |
| DE69434292D1 (de) | Für adseverin kodierendes gen | |
| ATE327321T1 (de) | Zyklische depsipeptid-synthasen, deren gene und system zur massenproduktion von zyklischen depsipeptiden | |
| IL135687A0 (en) | A novel human checkpoint kinase, hcds1, compositions and methods | |
| TR200403465T2 (tr) | Corynebacterium glutamicum gen kodlayıcı fosfonolpiruvat:seker fosfotransferaz sistem proteini | |
| EP0857789A3 (de) | Ferulasäure decarboxylase | |
| ATE268383T1 (de) | Interferon gene aus voegeln und rekombinante dna | |
| ATE342971T1 (de) | Den zellzyklus regulierende proteine | |
| ATE360688T1 (de) | Dna-fragment, dieses enthaltender rekombinanter vektor und verfahren zur expression von fremdgenen unter dessen verwendung | |
| PT811071E (pt) | Sequencias amolificadas derivadas do gene da desmina vectores que compreendem estas sequencias e suas utilizacoes para a producao de proteinas | |
| EP0812914A3 (de) | Prenyl Diphosphate Synthetase Gene | |
| WO1999054436A3 (en) | Nucleic acids and proteins of c. elegans insulin-like genes and uses thereof | |
| EP1291418A4 (de) | Neuartige glykosyltransferase-gene | |
| SE9503379D0 (sv) | A modified GAD, a method for producing a modified GAD, a method for supplying a modified GAD, a peptide and the use of an ordinary and/or a modified GAD | |
| EP0845536A3 (de) | Protein mit Ethylendiamine-N,N'-Dibarnsteinsäure: Ethylendiamin Lyase Aktivität und dafür kodierendes Gen | |
| DE60021707D1 (de) | Beta-primeverosidase gen | |
| TW200700554A (en) | Saponin-decomposing enzyme, gene thereof and large-scale production system for producing soyasapogenol b | |
| EP1291417A4 (de) | Neuartige (r)-2-hydroxy-3-phenylpropionat (d-phenyllaktat) dehydrogenase und für diese kodierendes gen | |
| ATE318920T1 (de) | Promotoren zur genexpression in karyopsen von pflanzen | |
| WO2000065055A3 (en) | Human transporter proteins | |
| CA2419038A1 (en) | Nucleic acid and protein increasing expression levels under salt stress | |
| EP1050580A4 (de) | Nukleinsäurefragmente, rekombinante vektoren, welche diese enthalten und verfahren zum unterstützen der expression von strukturellen genen durch anwendung derselben | |
| CA2439182A1 (en) | Novel calcium-independent phospholipases a2, genes thereof and promoter of the same |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |