ATE327768T1 - Sulfonierte chlorine als photosensitizer - Google Patents

Sulfonierte chlorine als photosensitizer

Info

Publication number
ATE327768T1
ATE327768T1 AT02753157T AT02753157T ATE327768T1 AT E327768 T1 ATE327768 T1 AT E327768T1 AT 02753157 T AT02753157 T AT 02753157T AT 02753157 T AT02753157 T AT 02753157T AT E327768 T1 ATE327768 T1 AT E327768T1
Authority
AT
Austria
Prior art keywords
meso
tetraphenylporphyrin
photosensitizers
sulfonated
chlorine
Prior art date
Application number
AT02753157T
Other languages
English (en)
Inventor
Kristian Berg
Diem Tran
P L Kristian Selbo
Claude Di Rimington
Original Assignee
Pci Biotech As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pci Biotech As filed Critical Pci Biotech As
Application granted granted Critical
Publication of ATE327768T1 publication Critical patent/ATE327768T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/008—Two-Photon or Multi-Photon PDT, e.g. with upconverting dyes or photosensitisers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Virology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Non-Reversible Transmitting Devices (AREA)
  • Cable Accessories (AREA)
AT02753157T 2001-08-30 2002-08-30 Sulfonierte chlorine als photosensitizer ATE327768T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0121023.6A GB0121023D0 (en) 2001-08-30 2001-08-30 Compound

Publications (1)

Publication Number Publication Date
ATE327768T1 true ATE327768T1 (de) 2006-06-15

Family

ID=9921225

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02753157T ATE327768T1 (de) 2001-08-30 2002-08-30 Sulfonierte chlorine als photosensitizer

Country Status (19)

Country Link
US (2) US7662807B2 (de)
EP (1) EP1420824B1 (de)
JP (1) JP5068920B2 (de)
KR (1) KR100883927B1 (de)
CN (1) CN100438909C (de)
AT (1) ATE327768T1 (de)
BR (1) BRPI0212172B8 (de)
CA (1) CA2457856C (de)
DE (1) DE60211918T2 (de)
ES (1) ES2265047T3 (de)
GB (1) GB0121023D0 (de)
HU (1) HU229623B1 (de)
MX (1) MXPA04001813A (de)
NO (1) NO332191B1 (de)
NZ (1) NZ531598A (de)
PL (1) PL206900B1 (de)
PT (1) PT1420824E (de)
RU (1) RU2323940C2 (de)
WO (1) WO2003020309A2 (de)

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GB0415263D0 (en) * 2004-07-07 2004-08-11 Norwegian Radium Hospital Res Method
FR2877943B1 (fr) 2004-11-16 2008-09-05 Univ De Coimbra Nouveaux derives de porphyrine, notamment chlorines et/ou bacteriochlorine, et leurs applications en therapie photodynamique
CN100361994C (zh) * 2004-12-10 2008-01-16 吉林大学 四苯基卟啉衍生物及其在有机电致发光器件中的应用
GB0613753D0 (en) 2006-07-11 2006-08-23 Norwegian Radium Hospital Res Method
CN101153085B (zh) * 2006-09-25 2010-05-12 中国科学院化学研究所 具有可逆手性的超分子手性膜及其制备方法
JP5290142B2 (ja) * 2007-02-19 2013-09-18 三栄源エフ・エフ・アイ株式会社 新規な糖連結クロリン誘導体
GB0811955D0 (en) 2008-06-30 2008-07-30 Pci Biotech As Method
KR100972504B1 (ko) * 2008-07-14 2010-07-26 김현종 휴대가 가능한 접철식 노트북 받침대
PT3459955T (pt) * 2008-09-18 2022-11-29 Biolitec Unternehmensberatungs Ii Ag Método e aplicação inovadores de porfirinas e cloros não simetricamente meso-substituídos para pdt
GB0819594D0 (en) * 2008-10-24 2008-12-03 Univ Coimbrra Process
GB0914287D0 (en) * 2009-08-14 2009-09-30 Pci Biotech As Compositions
GB0914286D0 (en) 2009-08-14 2009-09-30 Pci Biotech As Method
CN102260269B (zh) * 2010-05-25 2013-11-06 苏州和健医药科技有限公司 一种含有卟啉或二氢卟吩的树状化合物及其应用
CN102653541B (zh) * 2011-03-04 2014-01-15 国家纳米科学中心 一种卟啉化合物及其制备方法和应用
CN102786526B (zh) * 2011-05-20 2014-07-16 国家纳米科学中心 一种卟啉-酞菁二连体及其制备方法和应用
US8907081B2 (en) 2011-05-27 2014-12-09 Sharp Laboratories Of America, Inc. Long wavelength absorbing porphyrin photosensitizers for dye-sensitized solar cells
GB201208548D0 (en) 2012-05-15 2012-06-27 Pci Biotech As Compound and method
CN102952143B (zh) * 2012-11-08 2015-12-02 唐江涛 一种四苯基卟吩的制备方法
US20160040128A1 (en) * 2013-03-15 2016-02-11 Pci Biotech As Method
WO2015028575A1 (en) * 2013-08-28 2015-03-05 Pci Biotech As Immunisation method by photochemical internalisation
AU2014314149B2 (en) 2013-08-28 2019-12-19 Pci Biotech As Compound and method for vaccination and immunisation
CN108136016A (zh) 2014-08-28 2018-06-08 Pci生物技术公司 化合物和方法
CN104459099B (zh) * 2014-12-18 2016-04-13 东南大学 卟啉衍生物在制备检测炎症相关疾病试剂中的应用
GB201503776D0 (en) 2015-03-05 2015-04-22 Pci Biotech As Compound and method
RU2019109682A (ru) 2016-10-14 2020-11-16 ПиСиАй БИОТЕК АС Лечение холангиокарциномы с применением tpcs-2-индуцированной фотохимической интернализации гемцитабина
GB201718631D0 (en) 2017-11-10 2017-12-27 Pci Biotech As Method
GB201801169D0 (en) 2018-01-24 2018-03-07 Pci Biotech As Method
EP3823668A1 (de) 2018-07-16 2021-05-26 DCPrime B.V. Kombinationsprodukt zur verwendung in der tumorimpfung
MX2021009795A (es) * 2019-02-15 2021-09-08 Suncor Energy Inc Combinaciones de fotosensibilizador y agente quelante para usar como insecticidas.
WO2020217226A1 (en) 2019-04-25 2020-10-29 Dcprime B.V. Methods of tumor vaccination
CN112898310A (zh) * 2019-12-03 2021-06-04 中国石油天然气股份有限公司 地质卟啉加氢衍生化方法、所得加氢产物及同位素分析法
WO2021191870A1 (en) 2020-03-27 2021-09-30 Dcprime B.V. Ex vivo use of modified cells of leukemic origin for enhancing the efficacy of adoptive cell therapy
US20210322471A1 (en) 2020-03-27 2021-10-21 Dcprime B.V. In vivo use of modified cells of leukemic origin for enhancing the efficacy of adoptive cell therapy
KR20230033647A (ko) 2020-06-30 2023-03-08 멘두스 비.브이. 난소암 백신에서 백혈병 유래 세포의 용도
WO2022097068A1 (en) 2020-11-05 2022-05-12 Dcprime B.V. Use of tumor-independent antigens in immunotherapies
AU2022211682A1 (en) 2021-01-22 2023-08-03 Mendus B.V. Methods of tumor vaccination
WO2022190058A1 (en) 2021-03-12 2022-09-15 Dcprime B.V. Methods of vaccination and use of cd47 blockade

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HU204856B (en) 1987-08-12 1992-02-28 Orszagos Mueszaki Fejlesztesi Process for releasing cell mixtures and tissues from undesired populations and for producing monoclonal antibody - hematoporphyrin conjugates
JPH05253466A (ja) * 1992-03-12 1993-10-05 Res Dev Corp Of Japan 磁気異方性薄膜の製造方法
NO180167C (no) 1994-09-08 1997-02-26 Photocure As Fotokjemisk fremgangsmåte til å innföre molekyler i cellers cytosol
RU2066552C1 (ru) * 1996-02-12 1996-09-20 Товарищество с ограниченной ответственностью "Био Прогресс" Композиция для фотодинамического повреждения клеток-мишеней и способ фотодинамического повреждения клеток-мишеней
GB9700396D0 (en) 1997-01-10 1997-02-26 Photocure As Photochemotherapeutic compositions
JP2000007693A (ja) * 1998-06-26 2000-01-11 Lederle Japan Ltd クロリン誘導体
GB9905911D0 (en) 1999-03-15 1999-05-05 Photocure As Method
WO2000061584A1 (en) * 1999-04-14 2000-10-19 The University Of British Columbia IMPROVED β,β,-DIHYDROXY MESO-SUBSTITUTED CHLORINS, ISOBACTERIOCHLORINS, AND BACTERIOCHLORINS

Also Published As

Publication number Publication date
EP1420824A2 (de) 2004-05-26
PL206900B1 (pl) 2010-10-29
DE60211918D1 (en) 2006-07-06
PT1420824E (pt) 2006-08-31
MXPA04001813A (es) 2005-03-07
NZ531598A (en) 2005-09-30
CN1549729A (zh) 2004-11-24
EP1420824B1 (de) 2006-05-31
BR0212172A (pt) 2004-07-20
CA2457856A1 (en) 2003-03-13
US20060052433A1 (en) 2006-03-09
KR20040032983A (ko) 2004-04-17
HUP0401434A3 (en) 2008-05-28
BRPI0212172A8 (pt) 2018-12-18
US20100121255A1 (en) 2010-05-13
US7662807B2 (en) 2010-02-16
KR100883927B1 (ko) 2009-02-18
BRPI0212172B1 (pt) 2019-03-06
BRPI0212172B8 (pt) 2021-05-25
US8096419B2 (en) 2012-01-17
RU2323940C2 (ru) 2008-05-10
HK1060974A1 (en) 2004-09-03
ES2265047T3 (es) 2007-02-01
WO2003020309A3 (en) 2003-10-30
CN100438909C (zh) 2008-12-03
HU229623B1 (en) 2014-03-28
PL369289A1 (en) 2005-04-18
NO20040822L (no) 2004-04-29
CA2457856C (en) 2011-01-25
HUP0401434A2 (hu) 2004-12-28
AU2002313562B2 (en) 2006-09-07
JP2005507383A (ja) 2005-03-17
DE60211918T2 (de) 2007-01-18
WO2003020309A2 (en) 2003-03-13
GB0121023D0 (en) 2001-10-24
NO332191B1 (no) 2012-07-23
RU2004109228A (ru) 2005-04-10
JP5068920B2 (ja) 2012-11-07

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