NO332191B1 - Fotosensibiliserende midler omfattende sulfonerte mesotetrafenylchloriner, farmasoytiske preparater inneholdende slike midler, samt deres anvendelse ved fotokjemisk internalisering av molekyler og i fotodynamisk terapi - Google Patents

Fotosensibiliserende midler omfattende sulfonerte mesotetrafenylchloriner, farmasoytiske preparater inneholdende slike midler, samt deres anvendelse ved fotokjemisk internalisering av molekyler og i fotodynamisk terapi Download PDF

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Publication number
NO332191B1
NO332191B1 NO20040822A NO20040822A NO332191B1 NO 332191 B1 NO332191 B1 NO 332191B1 NO 20040822 A NO20040822 A NO 20040822A NO 20040822 A NO20040822 A NO 20040822A NO 332191 B1 NO332191 B1 NO 332191B1
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NO
Norway
Prior art keywords
photosensitizing agent
pharmaceutically acceptable
acceptable salt
cells
photosensitizing
Prior art date
Application number
NO20040822A
Other languages
English (en)
Norwegian (no)
Other versions
NO20040822L (no
Inventor
Kristian Berg
N N
Diem Tran
Pal Kristian Selbo
Original Assignee
Pci Biotech As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Pci Biotech As filed Critical Pci Biotech As
Publication of NO20040822L publication Critical patent/NO20040822L/no
Publication of NO332191B1 publication Critical patent/NO332191B1/no

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/008Two-Photon or Multi-Photon PDT, e.g. with upconverting dyes or photosensitisers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/12Keratolytics, e.g. wart or anti-corn preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Virology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Non-Reversible Transmitting Devices (AREA)
  • Cable Accessories (AREA)
NO20040822A 2001-08-30 2004-02-25 Fotosensibiliserende midler omfattende sulfonerte mesotetrafenylchloriner, farmasoytiske preparater inneholdende slike midler, samt deres anvendelse ved fotokjemisk internalisering av molekyler og i fotodynamisk terapi NO332191B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0121023.6A GB0121023D0 (en) 2001-08-30 2001-08-30 Compound
PCT/GB2002/003973 WO2003020309A2 (en) 2001-08-30 2002-08-30 Compound

Publications (2)

Publication Number Publication Date
NO20040822L NO20040822L (no) 2004-04-29
NO332191B1 true NO332191B1 (no) 2012-07-23

Family

ID=9921225

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20040822A NO332191B1 (no) 2001-08-30 2004-02-25 Fotosensibiliserende midler omfattende sulfonerte mesotetrafenylchloriner, farmasoytiske preparater inneholdende slike midler, samt deres anvendelse ved fotokjemisk internalisering av molekyler og i fotodynamisk terapi

Country Status (19)

Country Link
US (2) US7662807B2 (de)
EP (1) EP1420824B1 (de)
JP (1) JP5068920B2 (de)
KR (1) KR100883927B1 (de)
CN (1) CN100438909C (de)
AT (1) ATE327768T1 (de)
BR (1) BRPI0212172B8 (de)
CA (1) CA2457856C (de)
DE (1) DE60211918T2 (de)
ES (1) ES2265047T3 (de)
GB (1) GB0121023D0 (de)
HU (1) HU229623B1 (de)
MX (1) MXPA04001813A (de)
NO (1) NO332191B1 (de)
NZ (1) NZ531598A (de)
PL (1) PL206900B1 (de)
PT (1) PT1420824E (de)
RU (1) RU2323940C2 (de)
WO (1) WO2003020309A2 (de)

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GB0415263D0 (en) * 2004-07-07 2004-08-11 Norwegian Radium Hospital Res Method
FR2877943B1 (fr) 2004-11-16 2008-09-05 Univ De Coimbra Nouveaux derives de porphyrine, notamment chlorines et/ou bacteriochlorine, et leurs applications en therapie photodynamique
CN100361994C (zh) * 2004-12-10 2008-01-16 吉林大学 四苯基卟啉衍生物及其在有机电致发光器件中的应用
GB0613753D0 (en) 2006-07-11 2006-08-23 Norwegian Radium Hospital Res Method
CN101153085B (zh) * 2006-09-25 2010-05-12 中国科学院化学研究所 具有可逆手性的超分子手性膜及其制备方法
JP5290142B2 (ja) * 2007-02-19 2013-09-18 三栄源エフ・エフ・アイ株式会社 新規な糖連結クロリン誘導体
GB0811955D0 (en) 2008-06-30 2008-07-30 Pci Biotech As Method
KR100972504B1 (ko) * 2008-07-14 2010-07-26 김현종 휴대가 가능한 접철식 노트북 받침대
PT3459955T (pt) * 2008-09-18 2022-11-29 Biolitec Unternehmensberatungs Ii Ag Método e aplicação inovadores de porfirinas e cloros não simetricamente meso-substituídos para pdt
GB0819594D0 (en) * 2008-10-24 2008-12-03 Univ Coimbrra Process
GB0914287D0 (en) * 2009-08-14 2009-09-30 Pci Biotech As Compositions
GB0914286D0 (en) 2009-08-14 2009-09-30 Pci Biotech As Method
CN102260269B (zh) * 2010-05-25 2013-11-06 苏州和健医药科技有限公司 一种含有卟啉或二氢卟吩的树状化合物及其应用
CN102653541B (zh) * 2011-03-04 2014-01-15 国家纳米科学中心 一种卟啉化合物及其制备方法和应用
CN102786526B (zh) * 2011-05-20 2014-07-16 国家纳米科学中心 一种卟啉-酞菁二连体及其制备方法和应用
US8907081B2 (en) 2011-05-27 2014-12-09 Sharp Laboratories Of America, Inc. Long wavelength absorbing porphyrin photosensitizers for dye-sensitized solar cells
GB201208548D0 (en) 2012-05-15 2012-06-27 Pci Biotech As Compound and method
CN102952143B (zh) * 2012-11-08 2015-12-02 唐江涛 一种四苯基卟吩的制备方法
US20160040128A1 (en) * 2013-03-15 2016-02-11 Pci Biotech As Method
WO2015028575A1 (en) * 2013-08-28 2015-03-05 Pci Biotech As Immunisation method by photochemical internalisation
AU2014314149B2 (en) 2013-08-28 2019-12-19 Pci Biotech As Compound and method for vaccination and immunisation
CN108136016A (zh) 2014-08-28 2018-06-08 Pci生物技术公司 化合物和方法
CN104459099B (zh) * 2014-12-18 2016-04-13 东南大学 卟啉衍生物在制备检测炎症相关疾病试剂中的应用
GB201503776D0 (en) 2015-03-05 2015-04-22 Pci Biotech As Compound and method
RU2019109682A (ru) 2016-10-14 2020-11-16 ПиСиАй БИОТЕК АС Лечение холангиокарциномы с применением tpcs-2-индуцированной фотохимической интернализации гемцитабина
GB201718631D0 (en) 2017-11-10 2017-12-27 Pci Biotech As Method
GB201801169D0 (en) 2018-01-24 2018-03-07 Pci Biotech As Method
EP3823668A1 (de) 2018-07-16 2021-05-26 DCPrime B.V. Kombinationsprodukt zur verwendung in der tumorimpfung
MX2021009795A (es) * 2019-02-15 2021-09-08 Suncor Energy Inc Combinaciones de fotosensibilizador y agente quelante para usar como insecticidas.
WO2020217226A1 (en) 2019-04-25 2020-10-29 Dcprime B.V. Methods of tumor vaccination
CN112898310A (zh) * 2019-12-03 2021-06-04 中国石油天然气股份有限公司 地质卟啉加氢衍生化方法、所得加氢产物及同位素分析法
WO2021191870A1 (en) 2020-03-27 2021-09-30 Dcprime B.V. Ex vivo use of modified cells of leukemic origin for enhancing the efficacy of adoptive cell therapy
US20210322471A1 (en) 2020-03-27 2021-10-21 Dcprime B.V. In vivo use of modified cells of leukemic origin for enhancing the efficacy of adoptive cell therapy
KR20230033647A (ko) 2020-06-30 2023-03-08 멘두스 비.브이. 난소암 백신에서 백혈병 유래 세포의 용도
WO2022097068A1 (en) 2020-11-05 2022-05-12 Dcprime B.V. Use of tumor-independent antigens in immunotherapies
AU2022211682A1 (en) 2021-01-22 2023-08-03 Mendus B.V. Methods of tumor vaccination
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JPH05253466A (ja) * 1992-03-12 1993-10-05 Res Dev Corp Of Japan 磁気異方性薄膜の製造方法
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JP2000007693A (ja) * 1998-06-26 2000-01-11 Lederle Japan Ltd クロリン誘導体
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WO2000061584A1 (en) * 1999-04-14 2000-10-19 The University Of British Columbia IMPROVED β,β,-DIHYDROXY MESO-SUBSTITUTED CHLORINS, ISOBACTERIOCHLORINS, AND BACTERIOCHLORINS

Also Published As

Publication number Publication date
EP1420824A2 (de) 2004-05-26
PL206900B1 (pl) 2010-10-29
DE60211918D1 (en) 2006-07-06
ATE327768T1 (de) 2006-06-15
PT1420824E (pt) 2006-08-31
MXPA04001813A (es) 2005-03-07
NZ531598A (en) 2005-09-30
CN1549729A (zh) 2004-11-24
EP1420824B1 (de) 2006-05-31
BR0212172A (pt) 2004-07-20
CA2457856A1 (en) 2003-03-13
US20060052433A1 (en) 2006-03-09
KR20040032983A (ko) 2004-04-17
HUP0401434A3 (en) 2008-05-28
BRPI0212172A8 (pt) 2018-12-18
US20100121255A1 (en) 2010-05-13
US7662807B2 (en) 2010-02-16
KR100883927B1 (ko) 2009-02-18
BRPI0212172B1 (pt) 2019-03-06
BRPI0212172B8 (pt) 2021-05-25
US8096419B2 (en) 2012-01-17
RU2323940C2 (ru) 2008-05-10
HK1060974A1 (en) 2004-09-03
ES2265047T3 (es) 2007-02-01
WO2003020309A3 (en) 2003-10-30
CN100438909C (zh) 2008-12-03
HU229623B1 (en) 2014-03-28
PL369289A1 (en) 2005-04-18
NO20040822L (no) 2004-04-29
CA2457856C (en) 2011-01-25
HUP0401434A2 (hu) 2004-12-28
AU2002313562B2 (en) 2006-09-07
JP2005507383A (ja) 2005-03-17
DE60211918T2 (de) 2007-01-18
WO2003020309A2 (en) 2003-03-13
GB0121023D0 (en) 2001-10-24
RU2004109228A (ru) 2005-04-10
JP5068920B2 (ja) 2012-11-07

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