ATE328007T1 - Reinigung von fibrinogen aus flüssigkeiten mittels ausfällung und hydrophobischer- interaktion-chromatographie - Google Patents

Reinigung von fibrinogen aus flüssigkeiten mittels ausfällung und hydrophobischer- interaktion-chromatographie

Info

Publication number
ATE328007T1
ATE328007T1 AT99947668T AT99947668T ATE328007T1 AT E328007 T1 ATE328007 T1 AT E328007T1 AT 99947668 T AT99947668 T AT 99947668T AT 99947668 T AT99947668 T AT 99947668T AT E328007 T1 ATE328007 T1 AT E328007T1
Authority
AT
Austria
Prior art keywords
fibrinogen
hydrophobic interaction
interaction chromatography
purification
liquids
Prior art date
Application number
AT99947668T
Other languages
English (en)
Inventor
Graham Mccreath
Michael Udell
Original Assignee
Pharming Intellectual Pty Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9820848.1A external-priority patent/GB9820848D0/en
Priority claimed from GBGB9820847.3A external-priority patent/GB9820847D0/en
Priority claimed from GBGB9820845.7A external-priority patent/GB9820845D0/en
Application filed by Pharming Intellectual Pty Bv filed Critical Pharming Intellectual Pty Bv
Application granted granted Critical
Publication of ATE328007T1 publication Critical patent/ATE328007T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10—Polypeptides; Proteins
    • A61L24/106—Fibrin; Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/225—Fibrin; Fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/75—Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Surgery (AREA)
  • Hematology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Transplantation (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
AT99947668T 1998-09-24 1999-09-24 Reinigung von fibrinogen aus flüssigkeiten mittels ausfällung und hydrophobischer- interaktion-chromatographie ATE328007T1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB9820848.1A GB9820848D0 (en) 1998-09-24 1998-09-24 Purification
GBGB9820847.3A GB9820847D0 (en) 1998-09-24 1998-09-24 Method
GBGB9820845.7A GB9820845D0 (en) 1998-09-24 1998-09-24 Purification
US10332198P 1998-10-07 1998-10-07
US10331998P 1998-10-07 1998-10-07

Publications (1)

Publication Number Publication Date
ATE328007T1 true ATE328007T1 (de) 2006-06-15

Family

ID=27517474

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99947668T ATE328007T1 (de) 1998-09-24 1999-09-24 Reinigung von fibrinogen aus flüssigkeiten mittels ausfällung und hydrophobischer- interaktion-chromatographie

Country Status (9)

Country Link
US (2) US7211650B2 (de)
EP (1) EP1115745B1 (de)
AT (1) ATE328007T1 (de)
AU (1) AU6104799A (de)
DE (1) DE69931645T2 (de)
DK (1) DK1115745T3 (de)
ES (1) ES2267289T3 (de)
PT (1) PT1115745E (de)
WO (1) WO2000017239A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ518692A (en) * 1999-12-23 2004-08-27 Csl Ltd Purified fibrinogen free of destabilising levels of plasminogen and other proteases obtained from a Fraction I paste
DE102004009400A1 (de) 2004-02-24 2005-09-08 Zlb Behring Gmbh Fibrinogen Reinigung
US7531632B2 (en) 2006-02-16 2009-05-12 Gtc Biotherapeutics, Inc. Clarification of transgenic milk using depth filtration
WO2008135963A2 (en) * 2007-05-02 2008-11-13 Hemogem Inc. Fibrinogen for treatment of bleeding in trauma and platelet disorders
EP2077273B1 (de) 2007-12-31 2011-09-14 Animal Technology Institute Taiwan Verfahren zur Trennung von Casein aus löslichen Proteinen in einer Zusammensetzung
TWI346666B (en) 2007-12-31 2011-08-11 Animal Technology Inst Taiwan Method for seperating casein from casein-contained solution
US8557773B2 (en) 2008-05-02 2013-10-15 Laboratoire Francais Du Fractionnement Et Des Biotechnologies Treatment of bleeding with low half-life fibrinogen
ES2929654T3 (es) 2009-03-30 2022-11-30 Avery Dennison Corp Etiqueta adhesiva despegable que contiene una capa de película polimérica de alto módulo de tracción
MX351340B (es) 2012-03-13 2017-10-11 Octapharma Ag Proceso mejorado para la produccion de fibrinogeno y fibrinogeno producido por este.
US10188965B2 (en) 2012-12-05 2019-01-29 Csl Behring Gmbh Hydrophobic charge induction chromatographic depletion of a protein from a solution
US20140154233A1 (en) * 2012-12-05 2014-06-05 Csl Limited Method of purifying therapeutic proteins
FR3032621A1 (fr) 2015-02-13 2016-08-19 Lab Francais Du Fractionnement Colle biologique et son utilisation comme medicament
WO2017039547A1 (en) * 2015-09-04 2017-03-09 Nanyang Technological University Method of manufacturing a substrate with reduced threading dislocation density
KR20190026000A (ko) 2016-07-06 2019-03-12 라보라토이레 프란카이즈 듀 프락티온네먼트 에트 데스 바이오테크놀로지스 안정적 액체 피브리노겐
FR3061020B1 (fr) 2016-12-22 2019-05-17 Laboratoire Francais Du Fractionnement Et Des Biotechnologies Composition de fibrinogene humain
CN113214384B (zh) * 2021-04-26 2023-10-10 泰州博莱得利生物科技有限公司 犬纤维蛋白原的制备方法及其产品

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5598196A (en) * 1979-01-16 1980-07-25 Meito Sangyo Kk Fractionation of fibrinogen or its constituents and their use
GB8505882D0 (en) * 1985-03-07 1985-04-11 Central Blood Lab Authority Purification of blood coagulation factor viii
US5030215A (en) * 1990-01-03 1991-07-09 Cryolife, Inc. Preparation of fibrinogen/factor XIII precipitate
AU1461592A (en) * 1991-02-07 1992-09-07 Fibratek, Inc. Fibrinogen based adhesive
DE4240119A1 (de) * 1992-11-30 1994-06-01 Herbert Prof Dr Jennissen Verfahren zur Gewinnung von molekular einheitlichem, nativem, biologisch vollaktivem Fibrinogen aus Blut
ATE374525T1 (de) * 1994-02-18 2007-10-15 American Nat Red Cross Transgenes fibrinogen
US5639940A (en) * 1994-03-03 1997-06-17 Pharmaceutical Proteins Ltd. Production of fibrinogen in transgenic animals
ATE184884T1 (de) * 1994-07-14 1999-10-15 Croix Rouge De Belgique Fibrinogenkonzentrate aus blutplasma, verfahren und anlage für ihre herstellung
US6268487B1 (en) * 1996-05-13 2001-07-31 Genzyme Transgenics Corporation Purification of biologically active peptides from milk
US5935850A (en) * 1996-09-30 1999-08-10 The Research Foundation Of State University Of New York Model for cell migration and use thereof
US6037457A (en) * 1997-01-31 2000-03-14 The University Of North Carolina At Chapel Hill Method for recombinant fibrinogen production
KR100589082B1 (ko) * 1998-01-23 2006-06-13 씨에스엘 리미티드 피브리노겐 정제

Also Published As

Publication number Publication date
US20070219352A1 (en) 2007-09-20
EP1115745A1 (de) 2001-07-18
DE69931645T2 (de) 2007-05-16
US20020019025A1 (en) 2002-02-14
ES2267289T3 (es) 2007-03-01
EP1115745B1 (de) 2006-05-31
US7211650B2 (en) 2007-05-01
PT1115745E (pt) 2006-10-31
AU6104799A (en) 2000-04-10
DE69931645D1 (de) 2006-07-06
DK1115745T3 (da) 2006-10-02
WO2000017239A8 (en) 2000-06-22
WO2000017239A1 (en) 2000-03-30

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