ATE329616T1 - Virale nukleotidsequenz vr-2332 und nutzungsverfahren - Google Patents
Virale nukleotidsequenz vr-2332 und nutzungsverfahrenInfo
- Publication number
- ATE329616T1 ATE329616T1 AT95928746T AT95928746T ATE329616T1 AT E329616 T1 ATE329616 T1 AT E329616T1 AT 95928746 T AT95928746 T AT 95928746T AT 95928746 T AT95928746 T AT 95928746T AT E329616 T1 ATE329616 T1 AT E329616T1
- Authority
- AT
- Austria
- Prior art keywords
- nucleotide sequence
- sequences
- viral nucleotide
- nucleotide
- prrs
- Prior art date
Links
- 239000002773 nucleotide Substances 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 230000003612 virological effect Effects 0.000 title 1
- 208000005342 Porcine Reproductive and Respiratory Syndrome Diseases 0.000 abstract 2
- 241000700605 Viruses Species 0.000 abstract 2
- 125000003729 nucleotide group Chemical group 0.000 abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 108091034117 Oligonucleotide Proteins 0.000 abstract 1
- 108700026244 Open Reading Frames Proteins 0.000 abstract 1
- 238000012408 PCR amplification Methods 0.000 abstract 1
- 108010067390 Viral Proteins Proteins 0.000 abstract 1
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 238000009396 hybridization Methods 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 238000002255 vaccination Methods 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Communicable Diseases (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28794194A | 1994-08-05 | 1994-08-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE329616T1 true ATE329616T1 (de) | 2006-07-15 |
Family
ID=23105037
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95928746T ATE329616T1 (de) | 1994-08-05 | 1995-08-04 | Virale nukleotidsequenz vr-2332 und nutzungsverfahren |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5998601A (de) |
| EP (2) | EP1704869A1 (de) |
| JP (1) | JP3748887B2 (de) |
| AT (1) | ATE329616T1 (de) |
| CA (1) | CA2196555C (de) |
| DE (1) | DE69535061T2 (de) |
| DK (1) | DK0783321T3 (de) |
| ES (1) | ES2262142T3 (de) |
| MX (1) | MX9700817A (de) |
| PT (1) | PT783321E (de) |
| WO (1) | WO1996004010A1 (de) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69201441T3 (de) | 1991-06-06 | 2008-12-04 | Boehringer Ingelheim Vetmedica Gmbh | Erreger der mysteriösen schweinekrankheit,impfstoff-zusammensetzungen und diagnose kits. |
| US6773908B1 (en) * | 1992-10-30 | 2004-08-10 | Iowa State University Research Foundation, Inc. | Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV) |
| US6380376B1 (en) | 1992-10-30 | 2002-04-30 | Iowa State University Research Foundation | Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV) |
| US5695766A (en) * | 1992-10-30 | 1997-12-09 | Iowa State University Research Foundation | Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome |
| US6592873B1 (en) * | 1992-10-30 | 2003-07-15 | Iowa State University Research Foundation, Inc. | Polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus (PRRSV) and proteins encoded by the polynucleic acids |
| US20040224327A1 (en) * | 1996-10-30 | 2004-11-11 | Meulenberg Johanna Jacoba Maria | Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof |
| EP0839912A1 (de) * | 1996-10-30 | 1998-05-06 | Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) | Ansteckende Klone von RNA-Viren und darauf basierende Impfstoffe und diagnostisches Verfahren |
| EP1882696A3 (de) * | 1997-05-06 | 2008-03-05 | Boehringer Ingelheim Vetmedica Gmbh | PRRSV-Antigenstandorte, die Peptidsequenzen des PRRS-Virus identifizieren, zur Verwendung in Impfstoffen oder diagnostischen Assays |
| AU7960598A (en) * | 1997-06-05 | 1998-12-21 | Origen, Inc. | Recombinant porcine reproductive and respiratory syndrome virus (prrsv) for use as a vaccine |
| DE19836559A1 (de) * | 1998-08-12 | 2000-03-23 | Antigen Gmbh | Gefäß zur Entnahme von Blut |
| US7691389B2 (en) | 1998-12-22 | 2010-04-06 | Pfizer Inc | Infectious cDNA clone of north american porcine reproductive and respiratory syndrome (PRRS) virus and uses thereof |
| US7618797B2 (en) | 1998-12-22 | 2009-11-17 | Pfizer Inc | Infectious cDNA clone of North American porcine reproductive and respiratory syndrome (PRRS) virus and uses thereof |
| CA2290220C (en) | 1998-12-22 | 2013-11-19 | Pfizer Products Inc. | An infectious cdna clone of north american porcine reproductive and respiratory syndrome (prrs) virus and uses thereof |
| US7132106B2 (en) | 1998-12-22 | 2006-11-07 | Pfizer Inc. | Infectious cDNA clone of North American porcine reproductive and respiratory syndrome (PRRS) virus and uses thereof |
| CA2366072C (en) * | 1999-03-08 | 2007-07-10 | Id-Lelystad, Instituut Voor Dierhouderij En Diergezondheid B.V. | Prrsv vaccines |
| MXPA01010681A (es) | 1999-04-22 | 2003-08-20 | Us Agriculture | Vacuna de sindrome respiratorio y reproductiva porcina a base de ja-142 aislado. |
| EP1254213A2 (de) * | 2000-01-26 | 2002-11-06 | Boehringer Ingelheim Vetmedica Gmbh | Rekombinante attenuation von prrsv |
| WO2001059077A1 (en) * | 2000-02-08 | 2001-08-16 | Regents Of The University Of Minnesota | Porcine reproductive and respiratory syndrome virus and methods of use |
| EP1397498A1 (de) * | 2001-05-21 | 2004-03-17 | ID-Lelystad, Instituut voor Dierhouderij en Diergezondheid B.V. | Deletionen in arterivirus replikons |
| US6841364B2 (en) * | 2002-01-22 | 2005-01-11 | Protatek International, Inc. | Infectious cDNA clones of porcine reproductive and respiratory syndrome virus and expression vectors thereof |
| WO2005035794A2 (en) * | 2003-10-09 | 2005-04-21 | Tetracore, Inc. | Detection of prrsv |
| RU2007101725A (ru) | 2004-06-18 | 2008-07-27 | Риджентс Оф Дзе Юниверсити Оф Миннесота (Us) | Идентификация инфицированных вирусом и вакцинированных вирусом организмов |
| US7632636B2 (en) | 2004-09-21 | 2009-12-15 | Boehringer Ingelheim Vetmedica, Inc. | Porcine reproductive and respiratory syndrome isolates and methods of use |
| PL1856534T3 (pl) * | 2005-02-25 | 2017-08-31 | Idexx Laboratories, Inc. | Peptydy do wykrywania przeciwciała wirusa zespołu rozrodczo-oddechowego świń |
| CA2894069C (en) | 2005-06-24 | 2019-02-26 | Regents Of The University Of Minnesota | Prrs viruses, infectious clones, mutants thereof, and methods of use |
| US7666585B2 (en) * | 2007-06-15 | 2010-02-23 | Protatek International, Inc. | Construction of chimera PRRSV, compositions and vaccine preparations |
| ES2389748T3 (es) * | 2007-06-25 | 2012-10-31 | South Dakota State University | Virus del síndrome reproductivo y respiratorio porcino de tipo 1 norteamericano recombinante y métodos de uso |
| KR101653177B1 (ko) * | 2008-08-25 | 2016-09-01 | 베링거잉겔하임베트메디카인코퍼레이티드 | 고병원성 돼지 생식기 및 호흡기 증후군(hp prrs)에 대한 백신 |
| AR078253A1 (es) | 2009-09-02 | 2011-10-26 | Boehringer Ingelheim Vetmed | Metodos para reducir la actividad antivirica en composiciones pcv-2 y composiciones pcv-2 con mejor inmunogenicidad |
| UA108902C2 (uk) | 2010-11-10 | 2015-06-25 | Вірус північноамериканського репродуктивного та респіраторного синдрому свиней (prrs) та його застосування | |
| ES2550258T3 (es) | 2011-02-17 | 2015-11-05 | Boehringer Ingelheim Vetmedica Gmbh | Nueva cepa del PRRSV europea |
| SG192821A1 (en) | 2011-02-17 | 2013-09-30 | Boehringer Ingelheim Vetmed | Commercial scale process for production of prrsv |
| KR20140033096A (ko) * | 2011-05-07 | 2014-03-17 | 래보래토리오 아비-멕스, 에스.에이. 데 씨.브이. | 바이러스성 벡터를 이용한 prrs에 대한 재조합 백신 |
| CA2837375C (en) | 2011-06-01 | 2019-07-16 | Merial Limited | Needle-free administration of prrsv vaccines |
| US9187731B2 (en) | 2011-07-29 | 2015-11-17 | Boehringer Ingelheim Vetmedica Gmbh | PRRS virus inducing type I interferon in susceptible cells |
| EP2737059A1 (de) | 2011-07-29 | 2014-06-04 | Boehringer Ingelheim Vetmedica GmbH | Neuartiges prrs-virus zur induktion von interferon des typs i in empfindlichen zellen |
| CA2872789C (en) | 2012-05-17 | 2019-09-03 | Zoetis Llc | Effective vaccination against porcine reproductive and respiratory syndrome (prrs) virus prior to weaning |
| WO2014150822A2 (en) * | 2013-03-15 | 2014-09-25 | Boehringer Ingelheim Vetmedica, Inc. | Porcine reproductive and respiratory syndrome virus, compositions, vaccine and methods of use |
| ES3050936T3 (en) | 2015-06-23 | 2025-12-23 | Boehringer Ingelheim Vetmedica Gmbh | Prrsv minor protein-containing recombinant viral vectors and methods of making and use thereof |
| CN110072547B (zh) | 2016-12-14 | 2024-04-30 | 硕腾服务有限责任公司 | 断奶前对抗欧洲猪繁殖与呼吸综合征(prrs)病毒株的有效疫苗接种 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69201441T3 (de) * | 1991-06-06 | 2008-12-04 | Boehringer Ingelheim Vetmedica Gmbh | Erreger der mysteriösen schweinekrankheit,impfstoff-zusammensetzungen und diagnose kits. |
| DE601062T1 (de) * | 1991-08-26 | 1995-05-18 | David Allen Benfield | Vakzine gegen und diagnosemethode für das schweine-unfruchtbarkeits- und atmungs-syndrom (suas). |
| US5695766A (en) * | 1992-10-30 | 1997-12-09 | Iowa State University Research Foundation | Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome |
| ES2165405T3 (es) * | 1994-04-11 | 2002-03-16 | Akzo Nobel Nv | Cepas de vacuna europeas del virus del sindrome reproductor y respiratorio porcino (prrsv). |
-
1995
- 1995-08-04 PT PT95928746T patent/PT783321E/pt unknown
- 1995-08-04 DE DE69535061T patent/DE69535061T2/de not_active Revoked
- 1995-08-04 CA CA2196555A patent/CA2196555C/en not_active Expired - Lifetime
- 1995-08-04 EP EP06007265A patent/EP1704869A1/de not_active Withdrawn
- 1995-08-04 EP EP95928746A patent/EP0783321B1/de not_active Revoked
- 1995-08-04 MX MX9700817A patent/MX9700817A/es active IP Right Grant
- 1995-08-04 DK DK95928746T patent/DK0783321T3/da active
- 1995-08-04 AT AT95928746T patent/ATE329616T1/de active
- 1995-08-04 JP JP50679096A patent/JP3748887B2/ja not_active Expired - Lifetime
- 1995-08-04 ES ES95928746T patent/ES2262142T3/es not_active Expired - Lifetime
- 1995-08-04 WO PCT/US1995/009927 patent/WO1996004010A1/en not_active Ceased
-
1997
- 1997-02-13 US US08/799,464 patent/US5998601A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0783321A4 (de) | 1998-01-14 |
| JPH10504191A (ja) | 1998-04-28 |
| DE69535061D1 (de) | 2006-07-27 |
| EP0783321A1 (de) | 1997-07-16 |
| DE69535061T2 (de) | 2007-01-25 |
| CA2196555A1 (en) | 1996-02-15 |
| EP0783321B1 (de) | 2006-06-14 |
| MX9700817A (es) | 1997-05-31 |
| CA2196555C (en) | 2012-07-03 |
| EP1704869A1 (de) | 2006-09-27 |
| DK0783321T3 (da) | 2006-10-02 |
| ES2262142T3 (es) | 2006-11-16 |
| JP3748887B2 (ja) | 2006-02-22 |
| WO1996004010A1 (en) | 1996-02-15 |
| PT783321E (pt) | 2006-08-31 |
| US5998601A (en) | 1999-12-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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