ATE330014T1 - Verfahren zur herstellung von 1,3-propanediol durch einen rekombinanten micro-organismus in abwesenheit von coenzym b12 - Google Patents

Verfahren zur herstellung von 1,3-propanediol durch einen rekombinanten micro-organismus in abwesenheit von coenzym b12

Info

Publication number: ATE330014T1
Authority: AT; Austria
Prior art keywords: coenzyme; propanediol; organism; absence; producing
Prior art date: 1999-07-09

Application number

AT00949686T

Other languages

English (en)

Inventor

Patricia Sarcabal

Christian Croux

Philippe Soucaille

Original Assignee

Agronomique Inst Nat Rech

Inst Nat Sciences Appliq

Centre Nat Rech Scient

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-07-09

Filing date

2000-07-07

Publication date

2006-07-15

2000-07-07 Application filed by Agronomique Inst Nat Rech, Inst Nat Sciences Appliq, Centre Nat Rech Scient filed Critical Agronomique Inst Nat Rech

2006-07-15 Application granted granted Critical

2006-07-15 Publication of ATE330014T1 publication Critical patent/ATE330014T1/de

Links

DNIAPMSPPWPWGF-VKHMYHEASA-N (+)-propylene glycol Chemical compound C[C@H](O)CO DNIAPMSPPWPWGF-VKHMYHEASA-N 0.000 title abstract 3
YPFDHNVEDLHUCE-UHFFFAOYSA-N 1,3-propanediol Substances OCCCO YPFDHNVEDLHUCE-UHFFFAOYSA-N 0.000 title abstract 3
229920000166 polytrimethylene carbonate Polymers 0.000 title abstract 3
244000005700 microbiome Species 0.000 title abstract 2
239000005515 coenzyme Substances 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
OAJLVMGLJZXSGX-SLAFOUTOSA-L (2s,3s,4r,5r)-2-(6-aminopurin-9-yl)-5-methanidyloxolane-3,4-diol;cobalt(3+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7 Chemical compound [Co+3].O[C@H]1[C@@H](O)[C@@H]([CH2-])O[C@@H]1N1C2=NC=NC(N)=C2N=C1.[N-]([C@@H]1[C@H](CC(N)=O)[C@@]2(C)CCC(=O)NC[C@@H](C)OP([O-])(=O)O[C@H]3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)\C2=C(C)/C([C@H](C\2(C)C)CCC(N)=O)=N/C/2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O OAJLVMGLJZXSGX-SLAFOUTOSA-L 0.000 abstract 3
102000039446 nucleic acids Human genes 0.000 abstract 3
108020004707 nucleic acids Proteins 0.000 abstract 3
150000007523 nucleic acids Chemical class 0.000 abstract 3
238000000034 method Methods 0.000 abstract 2
239000002243 precursor Substances 0.000 abstract 2
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
101710088194 Dehydrogenase Proteins 0.000 abstract 1
108010025885 Glycerol dehydratase Proteins 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
229910052799 carbon Inorganic materials 0.000 abstract 1
230000003197 catalytic effect Effects 0.000 abstract 1
238000012258 culturing Methods 0.000 abstract 1
229920001184 polypeptide Polymers 0.000 abstract 1
102000004196 processed proteins & peptides Human genes 0.000 abstract 1
108090000765 processed proteins & peptides Proteins 0.000 abstract 1
BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 abstract 1
239000000126 substance Substances 0.000 abstract 1
238000003786 synthesis reaction Methods 0.000 abstract 1
239000013598 vector Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Engineering & Computer Science (AREA)
Wood Science & Technology (AREA)
Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
Microbiology (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Biomedical Technology (AREA)
Molecular Biology (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT00949686T 1999-07-09 2000-07-07 Verfahren zur herstellung von 1,3-propanediol durch einen rekombinanten micro-organismus in abwesenheit von coenzym b12 ATE330014T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9908939A FR2796081B1 (fr)	1999-07-09	1999-07-09	Procede de preparation du 1,3-propanediol par un micro-organisme recombinant en l'absence de coenzyme b12 ou de l'un de ses precurseurs
US10/043,639 US7267972B2 (en)	1999-07-09	2002-01-09	Method for preparing 1,3-propanediol by a recombinant micro-organism in the absence of coenzyme b12 or one of its precursors

Publications (1)

Publication Number	Publication Date
ATE330014T1 true ATE330014T1 (de)	2006-07-15

Family

ID=29720861

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT00949686T ATE330014T1 (de)	1999-07-09	2000-07-07	Verfahren zur herstellung von 1,3-propanediol durch einen rekombinanten micro-organismus in abwesenheit von coenzym b12

Country Status (11)

Country	Link
US (3)	US7267972B2 (de)
EP (1)	EP1200597B1 (de)
AT (1)	ATE330014T1 (de)
AU (1)	AU6296400A (de)
CY (1)	CY1105334T1 (de)
DE (1)	DE60028777T2 (de)
DK (1)	DK1200597T3 (de)
ES (1)	ES2264936T3 (de)
FR (1)	FR2796081B1 (de)
PT (1)	PT1200597E (de)
WO (1)	WO2001004324A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2796081B1 (fr)	1999-07-09	2003-09-26	Agronomique Inst Nat Rech	Procede de preparation du 1,3-propanediol par un micro-organisme recombinant en l'absence de coenzyme b12 ou de l'un de ses precurseurs
CN102031265A (zh)	2002-12-16	2011-04-27	纳幕尔杜邦公司	具有改善了的反应动力学的b12-依赖型脱水酶
CN1935991B (zh) *	2006-06-21	2010-05-12	南宁中诺生物工程有限责任公司	产气荚膜梭菌甘油脱水酶基因及其1,3-丙二醇的生产方法
WO2008052596A1 (en) *	2006-10-31	2008-05-08	Metabolic Explorer	Process for the biological production of n-butanol with high yield
US8236994B2 (en)	2006-10-31	2012-08-07	Metabolic Explorer	Process for the biological production of 1,3-propanediol from glycerol with high yield
DE102007027006A1 (de) *	2007-06-08	2008-12-11	Evonik Degussa Gmbh	Mikrobiologische Herstellung von Aldehyden, insbesondere von 3-Hydroxypropionaldehyd
WO2010076324A1 (en)	2008-12-31	2010-07-08	Metabolic Explorer	Method for the preparation of diols
EP2248904A1 (de) *	2009-05-05	2010-11-10	Metabolic Explorer	Kontinuierliche Kultur zur 1,3-Propandiol-Herstellung unter Verwendung einer hohen Glycerinkonzentration
DE102009002811A1 (de) *	2009-05-05	2010-11-11	Evonik Degussa Gmbh	Enzymatisches Verfahren zur Herstellung von Aldehyden
CN102666862A (zh)	2009-08-21	2012-09-12	马斯科马公司	在联合生物加工生物体中生产丙醇、醇和多元醇
WO2011042434A1 (en)	2009-10-05	2011-04-14	Metabolic Explorer	1,3-propanediol production with immobilised cells reactors
KR101090362B1 (ko)	2009-10-29	2011-12-07	한국생명공학연구원	글리세롤로부터 3-하이드록시프로피온산을 생산하는 새로운 방법
KR101220499B1 (ko) *	2010-05-25	2013-01-10	한국생명공학연구원	글리세롤로부터 3-하이드록시프로피온산을 고수율로 제조하는 방법
AR083799A1 (es) *	2010-11-10	2013-03-20	Metabolic Explorer Sa	Microorganismos para la produccion de 1,3-propanodiol usando concentracion de glicerina alta
EP2540834A1 (de) *	2011-06-29	2013-01-02	Metabolic Explorer	Verfahren zur Herstellung von 1,3-Propandiol
US8673602B2 (en) *	2011-08-16	2014-03-18	E I Du Pont De Nemours And Company	Recombinant bacteria having improved sucrose utilization
US9527953B2 (en)	2012-11-19	2016-12-27	Samsung Electronics Co., Ltd.	Continuous preparation for polyester
US9501147B2 (en) *	2013-12-29	2016-11-22	Immersion Corporation	Haptic device incorporating stretch characteristics
CA2993485C (en)	2015-07-27	2023-08-01	Institut National Des Sciences Appliquees	New polypeptide having ferredoxin-nadp+ reductase activity, polynucleotide encoding the same and uses thereof
PT3583221T (pt)	2017-02-20	2021-09-24	Metabolic Explorer Sa	Consórcio microbiano compreendendo clostridia para a produção de 1,3-propanodiol a partir de glicerol
EP3438270A1 (de)	2017-08-04	2019-02-06	Metabolic Explorer	Mikroorganismus und verfahren zur verbesserten 1,3-propandiol-herstellung durch fermentierung auf einem kulturmedium mit hohem glyceringehalt
KR20210043606A (ko)	2018-08-10	2021-04-21	메타볼릭 익스플로러	1,3-프로판디올 및 부티르산 생산이 개선된 미생물
KR20230076829A (ko) *	2020-09-30	2023-05-31	게노미엄, 아이엔씨.	바이오아크롤레인 및 바이오아크릴산을 생산하는 발효 공정
CN112358986B (zh) *	2020-11-09	2022-10-21	华南理工大学	一种丁酸梭菌及其在固定化发酵生产1，3-丙二醇的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5633362A (en)	1995-05-12	1997-05-27	E. I. Du Pont De Nemours And Company	Production of 1,3-propanediol from glycerol by recombinant bacteria expressing recombinant diol dehydratase
US5686276A (en)	1995-05-12	1997-11-11	E. I. Du Pont De Nemours And Company	Bioconversion of a fermentable carbon source to 1,3-propanediol by a single microorganism
DE69739715D1 (de)	1996-11-13	2010-02-04	Du Pont	Herstellungsverfahren von 1,3-propandiol durch rekombinante organismen
FR2796081B1 (fr)	1999-07-09	2003-09-26	Agronomique Inst Nat Rech	Procede de preparation du 1,3-propanediol par un micro-organisme recombinant en l'absence de coenzyme b12 ou de l'un de ses precurseurs

1999
- 1999-07-09 FR FR9908939A patent/FR2796081B1/fr not_active Expired - Lifetime
2000
- 2000-07-07 DE DE60028777T patent/DE60028777T2/de not_active Expired - Lifetime
- 2000-07-07 ES ES00949686T patent/ES2264936T3/es not_active Expired - Lifetime
- 2000-07-07 PT PT00949686T patent/PT1200597E/pt unknown
- 2000-07-07 EP EP00949686A patent/EP1200597B1/de not_active Expired - Lifetime
- 2000-07-07 DK DK00949686T patent/DK1200597T3/da active
- 2000-07-07 AU AU62964/00A patent/AU6296400A/en not_active Abandoned
- 2000-07-07 AT AT00949686T patent/ATE330014T1/de active
- 2000-07-07 WO PCT/FR2000/001981 patent/WO2001004324A1/fr not_active Ceased
2002
- 2002-01-09 US US10/043,639 patent/US7267972B2/en not_active Expired - Lifetime
2006
- 2006-09-12 CY CY20061101294T patent/CY1105334T1/el unknown
2007
- 2007-08-15 US US11/839,455 patent/US7695943B2/en not_active Expired - Fee Related
2010
- 2010-01-04 US US12/651,899 patent/US7858355B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
US20100129892A1 (en)	2010-05-27
DE60028777T2 (de)	2007-05-31
PT1200597E (pt)	2006-09-29
FR2796081A1 (fr)	2001-01-12
US7267972B2 (en)	2007-09-11
CY1105334T1 (el)	2010-03-03
AU6296400A (en)	2001-01-30
US20090029431A1 (en)	2009-01-29
US7858355B2 (en)	2010-12-28
WO2001004324A1 (fr)	2001-01-18
FR2796081B1 (fr)	2003-09-26
US20030175916A1 (en)	2003-09-18
EP1200597A1 (de)	2002-05-02
ES2264936T3 (es)	2007-02-01
US7695943B2 (en)	2010-04-13
EP1200597B1 (de)	2006-06-14
DE60028777D1 (de)	2006-07-27
DK1200597T3 (da)	2006-10-23

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2007-01-15

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