ATE330244T1 - Verfahren zur schätzung der besten anfangsfokussierung - Google Patents

Verfahren zur schätzung der besten anfangsfokussierung

Info

Publication number
ATE330244T1
ATE330244T1 AT02709458T AT02709458T ATE330244T1 AT E330244 T1 ATE330244 T1 AT E330244T1 AT 02709458 T AT02709458 T AT 02709458T AT 02709458 T AT02709458 T AT 02709458T AT E330244 T1 ATE330244 T1 AT E330244T1
Authority
AT
Austria
Prior art keywords
best initial
substrate
estimating
sample locations
initial focusing
Prior art date
Application number
AT02709458T
Other languages
English (en)
Inventor
Kim Ippolito
Oleg Lapets
Michael Sipe
Randall Shopoff
Original Assignee
Cellomics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cellomics Inc filed Critical Cellomics Inc
Application granted granted Critical
Publication of ATE330244T1 publication Critical patent/ATE330244T1/de

Links

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/24—Base structure
    • G02B21/241—Devices for focusing
    • G02B21/244—Devices for focusing using image analysis techniques
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B7/00—Mountings, adjusting means, or light-tight connections, for optical elements
    • G02B7/28—Systems for automatic generation of focusing signals

Landscapes

  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Microscoopes, Condenser (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Testing Of Optical Devices Or Fibers (AREA)
  • Measurement Of Optical Distance (AREA)
  • Automatic Focus Adjustment (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Paper (AREA)
AT02709458T 2001-02-02 2002-02-01 Verfahren zur schätzung der besten anfangsfokussierung ATE330244T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US26616301P 2001-02-02 2001-02-02

Publications (1)

Publication Number Publication Date
ATE330244T1 true ATE330244T1 (de) 2006-07-15

Family

ID=29549733

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02709458T ATE330244T1 (de) 2001-02-02 2002-02-01 Verfahren zur schätzung der besten anfangsfokussierung

Country Status (6)

Country Link
US (1) US6970789B2 (de)
EP (1) EP1368689B1 (de)
AT (1) ATE330244T1 (de)
DE (1) DE60212343T2 (de)
DK (1) DK1368689T3 (de)
WO (1) WO2002063367A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6711283B1 (en) 2000-05-03 2004-03-23 Aperio Technologies, Inc. Fully automatic rapid microscope slide scanner
US7668362B2 (en) 2000-05-03 2010-02-23 Aperio Technologies, Inc. System and method for assessing virtual slide image quality
US7518652B2 (en) 2000-05-03 2009-04-14 Aperio Technologies, Inc. Method and apparatus for pre-focus in a linear array based slide scanner
US6770892B2 (en) * 2002-02-28 2004-08-03 Agilent Technologies, Inc. Method and system for automated focus-distance determination for molecular array scanners
US7463761B2 (en) 2004-05-27 2008-12-09 Aperio Technologies, Inc. Systems and methods for creating and viewing three dimensional virtual slides
US7394943B2 (en) * 2004-06-30 2008-07-01 Applera Corporation Methods, software, and apparatus for focusing an optical system using computer image analysis
HUP0401802A2 (en) * 2004-09-02 2006-03-28 3D Histech Kft Focusing method object carriers on fast-moving digitalization and object carrier moving mechanics, focusing optic, optical distance-measuring instrument
US7548305B1 (en) * 2004-09-29 2009-06-16 Lockheed Martin Corporation Shallow angle shape sensor
WO2006097123A1 (en) * 2005-03-16 2006-09-21 European Molecular Biology Laboratory Autofocussing system for microscope systems
US8164622B2 (en) 2005-07-01 2012-04-24 Aperio Technologies, Inc. System and method for single optical axis multi-detector microscope slide scanner
JP4793179B2 (ja) * 2005-11-14 2011-10-12 オムロン株式会社 認証装置及び携帯端末
KR100912539B1 (ko) * 2007-12-06 2009-08-18 한국전자통신연구원 선형회귀와 스무딩을 이용한 엠비언트 디스플레이의거리보정 방법 및 시스템
US20100271536A1 (en) 2009-04-27 2010-10-28 Digital Imaging Systems Gmbh Blended autofocus using mechanical and softlens technologies
WO2011005238A1 (en) * 2009-07-08 2011-01-13 Freescale Semiconductor, Inc. Degree-of-focus determination module, position-of-best-focus selection modules, image processing module, imaging system, and corresponding method
US9398205B2 (en) * 2010-09-01 2016-07-19 Apple Inc. Auto-focus control using image statistics data with coarse and fine auto-focus scores
CA2826372C (en) * 2011-02-01 2020-03-31 Constitution Medical, Inc. Fast auto-focus in microscopic imaging
US9041791B2 (en) * 2011-02-01 2015-05-26 Roche Diagnostics Hematology, Inc. Fast auto-focus in imaging
JP5639670B2 (ja) 2013-02-01 2014-12-10 浜松ホトニクス株式会社 画像取得装置及び撮像装置
US9903806B2 (en) * 2013-12-17 2018-02-27 Nanometrics Incorporated Focusing system with filter for open or closed loop control
GB2534402A (en) 2015-01-22 2016-07-27 Idea Biomedical Ltd Auto-focussing method and device
US9715721B2 (en) 2015-12-18 2017-07-25 Sony Corporation Focus detection
WO2021104776A1 (en) * 2019-11-29 2021-06-03 Robert Bosch Gmbh A control unit for focusing a sample and a method thereof
EP4194918A1 (de) * 2021-12-10 2023-06-14 Leica Microsystems CMS GmbH Verfahren zur steuerung einer mikroskopischen abbildung und entsprechende mikroskopsteuerungsanordnung und mikroskop
DE102023127302A1 (de) * 2023-10-06 2025-04-10 Leica Microsystems Cms Gmbh Verfahren zum Erzeugen einer Vielzahl von Fokuspunkten für unterschiedliche Positionen
CN117132646B (zh) * 2023-10-26 2024-01-05 湖南自兴智慧医疗科技有限公司 基于深度学习的分裂相自动对焦系统

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4751179A (en) * 1984-05-31 1988-06-14 Coulter Electronics, Inc. Method and reagents for differential determination of four populations of leukocytes in blood
JP2597961B2 (ja) * 1987-10-21 1997-04-09 キヤノン株式会社 自動焦点調節装置
US5060002A (en) * 1988-02-11 1991-10-22 Canon Kabushiki Kaisha Automatic focus adjusting device
JP2713978B2 (ja) * 1988-05-13 1998-02-16 キヤノン株式会社 カメラのための自動焦点調節装置
JP3010681B2 (ja) * 1990-05-22 2000-02-21 株式会社ニコン 自動焦点調節装置
US5784162A (en) * 1993-08-18 1998-07-21 Applied Spectral Imaging Ltd. Spectral bio-imaging methods for biological research, medical diagnostics and therapy
US5991028A (en) * 1991-02-22 1999-11-23 Applied Spectral Imaging Ltd. Spectral bio-imaging methods for cell classification
US5790710A (en) * 1991-07-12 1998-08-04 Jeffrey H. Price Autofocus system for scanning microscopy
US5548661A (en) * 1991-07-12 1996-08-20 Price; Jeffrey H. Operator independent image cytometer
US5200754A (en) 1991-11-27 1993-04-06 Hughes Aircraft Company Fourth-order-product phase difference autofocus
US5857258A (en) * 1992-03-13 1999-01-12 The United States Of America As Represented By The Secretary Of Commerce Electrical test structure and method for measuring the relative locations of conductive features on an insulating substrate
US5325449A (en) * 1992-05-15 1994-06-28 David Sarnoff Research Center, Inc. Method for fusing images and apparatus therefor
JP3171923B2 (ja) * 1992-05-26 2001-06-04 ジーイー横河メディカルシステム株式会社 Ｃｔ装置における脂肪分布の画像生成方法
US5355215A (en) * 1992-09-30 1994-10-11 Environmental Research Institute Of Michigan Method and apparatus for quantitative fluorescence measurements
US5659384A (en) * 1993-04-09 1997-08-19 Canon Kabushiki Kaisha Position detection apparatus and method
GB9404997D0 (en) 1994-03-15 1994-04-27 Imtec Group The Ltd Microfilm imaging
JP3444551B2 (ja) * 1994-05-11 2003-09-08 オリンパス光学工業株式会社 カメラの焦点検出装置
JPH10502466A (ja) 1994-07-01 1998-03-03 ジェフレイ エイチ． プライス， スキャニングマイクロスコピー用オートフォーカスシステム
JPH0862484A (ja) * 1994-08-24 1996-03-08 Nikon Corp 焦点調節装置
JP3635687B2 (ja) * 1994-09-07 2005-04-06 株式会社ニコン 自動合焦装置
US5557097A (en) * 1994-09-20 1996-09-17 Neopath, Inc. Cytological system autofocus integrity checking apparatus
WO1996010237A1 (en) * 1994-09-20 1996-04-04 Neopath, Inc. Biological specimen analysis system processing integrity checking apparatus
IL111229A (en) * 1994-10-10 1998-06-15 Nova Measuring Instr Ltd Autofocusing microscope
US5589351A (en) * 1994-12-06 1996-12-31 Nps Pharmaceuticals, Inc. Fluorescence detection apparatus
JPH08219812A (ja) * 1995-02-15 1996-08-30 Canon Inc 変位情報検出装置、変位情報検出用スケール及びこれを用いたドライブ制御装置
US5686308A (en) * 1995-06-08 1997-11-11 Coulter Corporation Reagent and method for differential determination of leukocytes in blood
US5843608A (en) * 1995-06-08 1998-12-01 Coulter International Corp. Reagent and method for differential determination of leukocytes in blood
US5882933A (en) * 1995-06-08 1999-03-16 Coulter International Corp. Method for determination of leukocytes and hemoglobin concentration in blood
US5786224A (en) * 1995-06-29 1998-07-28 Coulter Corporation Reagent and method for differential determination of leukocytes in blood
JPH0968644A (ja) * 1995-08-31 1997-03-11 Nikon Corp 自動焦点調節装置
US6031232A (en) * 1995-11-13 2000-02-29 Bio-Rad Laboratories, Inc. Method for the detection of malignant and premalignant stages of cervical cancer
US6028667A (en) * 1996-05-13 2000-02-22 Process Instruments, Inc. Compact and robust spectrograph
US5989835A (en) * 1997-02-27 1999-11-23 Cellomics, Inc. System for cell-based screening
CH692254A5 (de) * 1996-06-29 2002-04-15 Zeiss Carl Mikroskop mit einer Autofokus-Anordnung.
JPH1096848A (ja) * 1996-09-20 1998-04-14 Olympus Optical Co Ltd 自動焦点検出装置
US6259080B1 (en) * 1998-03-18 2001-07-10 Olympus Optical Co. Ltd. Autofocus device for microscope
US6248988B1 (en) * 1998-05-05 2001-06-19 Kla-Tencor Corporation Conventional and confocal multi-spot scanning optical microscope
US6201619B1 (en) * 1998-06-18 2001-03-13 Agfa Corporation Autofocus process and system with fast multi-region sampling
WO2000039578A2 (en) 1998-12-23 2000-07-06 Foss Electric A/S Method and apparatus for estimation of a cell count in a body fluid
US6130745A (en) * 1999-01-07 2000-10-10 Biometric Imaging, Inc. Optical autofocus for use with microtiter plates
JP2003501693A (ja) 1999-06-04 2003-01-14 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 顕微鏡用の強固な自動焦点システム
US6486457B1 (en) 1999-10-07 2002-11-26 Agilent Technologies, Inc. Apparatus and method for autofocus

Also Published As

Publication number Publication date
EP1368689B1 (de) 2006-06-14
EP1368689A1 (de) 2003-12-10
US20020172964A1 (en) 2002-11-21
US6970789B2 (en) 2005-11-29
DK1368689T3 (da) 2006-09-18
DE60212343T2 (de) 2007-06-14
DE60212343D1 (de) 2006-07-27
WO2002063367A1 (en) 2002-08-15

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