ATE330939T1 - Schwefel enthaltende aminosäurederivate - Google Patents
Schwefel enthaltende aminosäurederivateInfo
- Publication number
- ATE330939T1 ATE330939T1 AT97939187T AT97939187T ATE330939T1 AT E330939 T1 ATE330939 T1 AT E330939T1 AT 97939187 T AT97939187 T AT 97939187T AT 97939187 T AT97939187 T AT 97939187T AT E330939 T1 ATE330939 T1 AT E330939T1
- Authority
- AT
- Austria
- Prior art keywords
- substituted
- amino acid
- alkyl
- acid derivatives
- containing sulfur
- Prior art date
Links
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 title abstract 3
- 150000003862 amino acid derivatives Chemical class 0.000 title abstract 3
- 229910052717 sulfur Inorganic materials 0.000 title abstract 3
- 239000011593 sulfur Substances 0.000 title abstract 3
- -1 (substituted) phenyl Chemical group 0.000 abstract 5
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000002947 alkylene group Chemical group 0.000 abstract 2
- 102100022118 Leukotriene A-4 hydrolase Human genes 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 125000004438 haloalkoxy group Chemical group 0.000 abstract 1
- 125000001188 haloalkyl group Chemical group 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 108010072713 leukotriene A4 hydrolase Proteins 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/64—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton
- C07C323/65—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton containing sulfur atoms of sulfone or sulfoxide groups bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C329/00—Thiocarbonic acids; Halides, esters or anhydrides thereof
- C07C329/02—Monothiocarbonic acids; Derivatives thereof
- C07C329/04—Esters of monothiocarbonic acids
- C07C329/06—Esters of monothiocarbonic acids having sulfur atoms of thiocarbonic groups bound to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP23514596 | 1996-09-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE330939T1 true ATE330939T1 (de) | 2006-07-15 |
Family
ID=16981728
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97939187T ATE330939T1 (de) | 1996-09-05 | 1997-09-05 | Schwefel enthaltende aminosäurederivate |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US6046235A (de) |
| EP (1) | EP0947502B1 (de) |
| AT (1) | ATE330939T1 (de) |
| DE (1) | DE69736189T2 (de) |
| ES (1) | ES2262188T3 (de) |
| WO (1) | WO1998009943A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7851486B2 (en) | 2002-10-17 | 2010-12-14 | Decode Genetics Ehf. | Susceptibility gene for myocardial infarction, stroke, and PAOD; methods of treatment |
| US7507531B2 (en) | 2002-10-17 | 2009-03-24 | Decode Genetics Chf. | Use of 5-lipoxygenase activating protein (FLAP) gene to assess susceptibility for myocardial infarction |
| WO2005027886A2 (en) * | 2003-09-17 | 2005-03-31 | Decode Genetics Ehf. | Methods of preventing or treating recurrence of myocardial infarction |
| US8158362B2 (en) | 2005-03-30 | 2012-04-17 | Decode Genetics Ehf. | Methods of diagnosing susceptibility to myocardial infarction and screening for an LTA4H haplotype |
| EP4731739A1 (de) * | 2023-06-21 | 2026-04-29 | Givaudan SA | Neue verbindungen |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61165362A (ja) * | 1985-01-18 | 1986-07-26 | Meito Sangyo Kk | メルカプト脂肪酸類誘導体およびその利用 |
| US4749688A (en) * | 1986-06-20 | 1988-06-07 | Schering Corporation | Use of neutral metalloendopeptidase inhibitors in the treatment of hypertension |
| EP0254032A3 (de) * | 1986-06-20 | 1990-09-05 | Schering Corporation | Hemmer der neutralen Metallendopeptidase zur Behandlung von Hypertension |
| AU615976B2 (en) * | 1987-12-16 | 1991-10-17 | Schering Corporation | Mercapto-acylamino acid antihypertensives |
| JPH0686419B2 (ja) * | 1988-01-25 | 1994-11-02 | 参天製薬株式会社 | システイン関連化合物 |
| US5292926A (en) * | 1988-01-25 | 1994-03-08 | Santen Pharmaceutical Co., Ltd. | Cysteine derivatives |
| EP0360246B1 (de) * | 1988-09-21 | 1994-03-30 | G.D. Searle & Co. | 3-Oxiranbenzoesäuren und Derivate |
| JP2503799B2 (ja) | 1991-03-20 | 1996-06-05 | 双葉電子工業株式会社 | グラフィック蛍光表示管 |
| JP2909620B2 (ja) * | 1995-03-07 | 1999-06-23 | 参天製薬株式会社 | N,n−ジアルキルアミノフェニル基を有する新規アミノ酸誘導体 |
-
1997
- 1997-09-05 EP EP97939187A patent/EP0947502B1/de not_active Expired - Lifetime
- 1997-09-05 US US09/254,160 patent/US6046235A/en not_active Expired - Fee Related
- 1997-09-05 AT AT97939187T patent/ATE330939T1/de not_active IP Right Cessation
- 1997-09-05 DE DE69736189T patent/DE69736189T2/de not_active Expired - Fee Related
- 1997-09-05 ES ES97939187T patent/ES2262188T3/es not_active Expired - Lifetime
- 1997-09-05 WO PCT/JP1997/003124 patent/WO1998009943A1/ja not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| ES2262188T3 (es) | 2006-11-16 |
| US6046235A (en) | 2000-04-04 |
| WO1998009943A1 (fr) | 1998-03-12 |
| DE69736189D1 (de) | 2006-08-03 |
| DE69736189T2 (de) | 2007-04-26 |
| EP0947502B1 (de) | 2006-06-21 |
| EP0947502A4 (de) | 2004-12-01 |
| EP0947502A1 (de) | 1999-10-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |