ATE331044T1 - Verfahren zur integrierten integritätsbewertung und analyse von nukleinsäuren - Google Patents

Verfahren zur integrierten integritätsbewertung und analyse von nukleinsäuren

Info

Publication number
ATE331044T1
ATE331044T1 AT03025294T AT03025294T ATE331044T1 AT E331044 T1 ATE331044 T1 AT E331044T1 AT 03025294 T AT03025294 T AT 03025294T AT 03025294 T AT03025294 T AT 03025294T AT E331044 T1 ATE331044 T1 AT E331044T1
Authority
AT
Austria
Prior art keywords
rrna
control
probes
control probe
complementary
Prior art date
Application number
AT03025294T
Other languages
English (en)
Inventor
Colin Ingham
Original Assignee
Pamgene Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pamgene Bv filed Critical Pamgene Bv
Application granted granted Critical
Publication of ATE331044T1 publication Critical patent/ATE331044T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00608—DNA chips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00612—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports the surface being inorganic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00632—Introduction of reactive groups to the surface
    • B01J2219/00637—Introduction of reactive groups to the surface by coating it with another layer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00639—Making arrays on substantially continuous surfaces the compounds being trapped in or bound to a porous medium
    • B01J2219/00641—Making arrays on substantially continuous surfaces the compounds being trapped in or bound to a porous medium the porous medium being continuous, e.g. porous oxide substrates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068—Means for controlling the apparatus of the process
    • B01J2219/00693—Means for quality control
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00722—Nucleotides
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT03025294T 2003-03-04 2003-11-06 Verfahren zur integrierten integritätsbewertung und analyse von nukleinsäuren ATE331044T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03447045 2003-03-04
EP03025294A EP1457573B1 (de) 2003-03-04 2003-11-06 Verfahren zur integrierten Integritätsbewertung und Analyse von Nukleinsäuren

Publications (1)

Publication Number Publication Date
ATE331044T1 true ATE331044T1 (de) 2006-07-15

Family

ID=32773643

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03025294T ATE331044T1 (de) 2003-03-04 2003-11-06 Verfahren zur integrierten integritätsbewertung und analyse von nukleinsäuren

Country Status (5)

Country Link
US (1) US7504209B2 (de)
EP (1) EP1457573B1 (de)
AT (1) ATE331044T1 (de)
DE (1) DE60306328T2 (de)
WO (1) WO2004079005A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1457573B1 (de) * 2003-03-04 2006-06-21 PamGene B.V. Verfahren zur integrierten Integritätsbewertung und Analyse von Nukleinsäuren
EP1772522A1 (de) * 2005-10-04 2007-04-11 Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno Kontrolle der Konservierung mit Biomarkern
EP2024725B1 (de) * 2007-05-08 2013-11-20 Agilent Technologies, Inc. Probenherstellungsvorrichtung und -verfahren unter Verwendung eines Polyamid-Rohrs
EP2841602B1 (de) * 2012-04-23 2017-06-21 Monoquant Pty Ltd Verfahren zur bestimmung der rna-integrität
US11031096B2 (en) 2012-04-24 2021-06-08 Rna Diagnostics Inc. Method for determining efficacy of chemotherapy treatment for a subject
US9422602B2 (en) 2012-08-15 2016-08-23 Bio-Rad Laboratories, Inc. Methods and compositions for determining nucleic acid degradation
ES2716280T3 (es) 2012-12-03 2019-06-11 Rna Diagnostics Inc Métodos para controlar la respuesta a las radioterapias en cáncer
WO2015048887A1 (en) 2013-10-04 2015-04-09 Rna Diagnostics Inc. Rna disruption assay for predicting survival
US11124823B2 (en) * 2015-06-01 2021-09-21 Becton, Dickinson And Company Methods for RNA quantification
EP3452614B1 (de) 2016-05-02 2023-06-28 Becton, Dickinson and Company Genaue molekulare barcodierung
CN111492068B (zh) 2017-12-19 2025-03-21 贝克顿迪金森公司 与寡核苷酸相关联的颗粒
WO2020150356A1 (en) 2019-01-16 2020-07-23 Becton, Dickinson And Company Polymerase chain reaction normalization through primer titration

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5543499A (en) * 1993-10-29 1996-08-06 Wake Forest University DNA sequence encoding a polypeptide with anti-tumor properties
US20030087265A1 (en) * 2000-01-21 2003-05-08 Edward Sauter Specific microarrays for breast cancer screening
CA2327527A1 (en) * 2000-12-27 2002-06-27 Geneka Biotechnologie Inc. Method for the normalization of the relative fluorescence intensities of two rna samples in hybridization arrays
EP1572869A2 (de) * 2001-04-02 2005-09-14 Cornell Research Foundation, Inc. Pseudomonas avr- und hop-proteine, diese codierende nukleinsäuren und verwendung davon
WO2002099064A2 (en) * 2001-06-05 2002-12-12 Gene Logic, Inc. Rna purification methods
US7011947B2 (en) * 2001-07-17 2006-03-14 Whitehead Institute For Biomedical Research MLL translocations specify a distinct gene expression profile, distinguishing a unique leukemia
US20030082596A1 (en) * 2001-08-08 2003-05-01 Michael Mittmann Methods of genetic analysis of probes: test3
JP2005503145A (ja) * 2001-08-16 2005-02-03 ザ ユナイテッド ステイツ オブ アメリカ リプレゼンティッド バイ ザ シークレタリー デパートメント オブ ヘルス アンド ヒューマン サービシーズ 非小細胞肺癌の分子特性
EP1457573B1 (de) * 2003-03-04 2006-06-21 PamGene B.V. Verfahren zur integrierten Integritätsbewertung und Analyse von Nukleinsäuren
JP2006524056A (ja) * 2003-04-07 2006-10-26 リボノミックス， インコーポレイテッド グルコース代謝および脂質代謝に関与する治療標的を同定するための方法

Also Published As

Publication number Publication date
EP1457573A1 (de) 2004-09-15
DE60306328D1 (de) 2006-08-03
EP1457573B1 (de) 2006-06-21
US7504209B2 (en) 2009-03-17
US20070259340A1 (en) 2007-11-08
DE60306328T2 (de) 2007-04-26
WO2004079005A1 (en) 2004-09-16

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