ATE331044T1 - Verfahren zur integrierten integritätsbewertung und analyse von nukleinsäuren - Google Patents

Verfahren zur integrierten integritätsbewertung und analyse von nukleinsäuren

Info

Publication number
ATE331044T1
ATE331044T1 AT03025294T AT03025294T ATE331044T1 AT E331044 T1 ATE331044 T1 AT E331044T1 AT 03025294 T AT03025294 T AT 03025294T AT 03025294 T AT03025294 T AT 03025294T AT E331044 T1 ATE331044 T1 AT E331044T1
Authority
AT
Austria
Prior art keywords
rrna
control
probes
control probe
complementary
Prior art date
Application number
AT03025294T
Other languages
English (en)
Inventor
Colin Ingham
Original Assignee
Pamgene Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pamgene Bv filed Critical Pamgene Bv
Application granted granted Critical
Publication of ATE331044T1 publication Critical patent/ATE331044T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00608—DNA chips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00612—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports the surface being inorganic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00632—Introduction of reactive groups to the surface
    • B01J2219/00637—Introduction of reactive groups to the surface by coating it with another layer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00639—Making arrays on substantially continuous surfaces the compounds being trapped in or bound to a porous medium
    • B01J2219/00641—Making arrays on substantially continuous surfaces the compounds being trapped in or bound to a porous medium the porous medium being continuous, e.g. porous oxide substrates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068—Means for controlling the apparatus of the process
    • B01J2219/00693—Means for quality control
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00722—Nucleotides
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT03025294T 2003-03-04 2003-11-06 Verfahren zur integrierten integritätsbewertung und analyse von nukleinsäuren ATE331044T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03447045 2003-03-04
EP03025294A EP1457573B1 (de) 2003-03-04 2003-11-06 Verfahren zur integrierten Integritätsbewertung und Analyse von Nukleinsäuren

Publications (1)

Publication Number Publication Date
ATE331044T1 true ATE331044T1 (de) 2006-07-15

Family

ID=32773643

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03025294T ATE331044T1 (de) 2003-03-04 2003-11-06 Verfahren zur integrierten integritätsbewertung und analyse von nukleinsäuren

Country Status (5)

Country Link
US (1) US7504209B2 (de)
EP (1) EP1457573B1 (de)
AT (1) ATE331044T1 (de)
DE (1) DE60306328T2 (de)
WO (1) WO2004079005A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE331044T1 (de) * 2003-03-04 2006-07-15 Pamgene Bv Verfahren zur integrierten integritätsbewertung und analyse von nukleinsäuren
EP1772522A1 (de) * 2005-10-04 2007-04-11 Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno Kontrolle der Konservierung mit Biomarkern
US8883089B2 (en) * 2007-05-08 2014-11-11 Agilent Technologies, Inc. Sample preparation device and method utilizing polyamide tube
CN104769130A (zh) 2012-04-23 2015-07-08 莫诺夸特有限公司 一种确定rna完整性的方法
CN104640998B (zh) 2012-04-24 2018-08-14 Rna诊断公司 用于评估rna断裂的试验、方法和设备
US9422602B2 (en) 2012-08-15 2016-08-23 Bio-Rad Laboratories, Inc. Methods and compositions for determining nucleic acid degradation
AU2013354857B2 (en) 2012-12-03 2019-05-02 Rna Diagnostics Inc. Methods and kits for monitoring response to radiation therapies in cancer
US10731222B2 (en) 2013-10-04 2020-08-04 Rna Diagnostics Inc. RNA disruption assay for predicting survival
WO2016196229A1 (en) * 2015-06-01 2016-12-08 Cellular Research, Inc. Methods for rna quantification
JP7129343B2 (ja) 2016-05-02 2022-09-01 ベクトン・ディキンソン・アンド・カンパニー 正確な分子バーコーディング
EP3728636B1 (de) 2017-12-19 2024-09-11 Becton, Dickinson and Company Mit oligonukleotiden assoziierte teilchen
US11371076B2 (en) 2019-01-16 2022-06-28 Becton, Dickinson And Company Polymerase chain reaction normalization through primer titration

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5543499A (en) * 1993-10-29 1996-08-06 Wake Forest University DNA sequence encoding a polypeptide with anti-tumor properties
US20030087265A1 (en) * 2000-01-21 2003-05-08 Edward Sauter Specific microarrays for breast cancer screening
CA2327527A1 (en) * 2000-12-27 2002-06-27 Geneka Biotechnologie Inc. Method for the normalization of the relative fluorescence intensities of two rna samples in hybridization arrays
WO2002079390A2 (en) * 2001-04-02 2002-10-10 Cornell Research Foundation, Inc. $i(pesudomonas) avr and hop proteins, their encoding nucleic acids, and use thereof
WO2002099064A2 (en) * 2001-06-05 2002-12-12 Gene Logic, Inc. Rna purification methods
US7011947B2 (en) * 2001-07-17 2006-03-14 Whitehead Institute For Biomedical Research MLL translocations specify a distinct gene expression profile, distinguishing a unique leukemia
US20030082596A1 (en) * 2001-08-08 2003-05-01 Michael Mittmann Methods of genetic analysis of probes: test3
AU2002355963A1 (en) * 2001-08-16 2003-03-03 Genzyme Corporation Molecular characteristics of non-small cell lung cancer
ATE331044T1 (de) * 2003-03-04 2006-07-15 Pamgene Bv Verfahren zur integrierten integritätsbewertung und analyse von nukleinsäuren
AU2004230658A1 (en) * 2003-04-07 2004-10-28 Ribonomics Inc. Methods for identifying therapeutic targets involved in glucose and lipid metabolism

Also Published As

Publication number Publication date
US20070259340A1 (en) 2007-11-08
DE60306328T2 (de) 2007-04-26
WO2004079005A1 (en) 2004-09-16
US7504209B2 (en) 2009-03-17
EP1457573A1 (de) 2004-09-15
DE60306328D1 (de) 2006-08-03
EP1457573B1 (de) 2006-06-21

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