ATE553216T1 - Sonden, bibliotheken und kits zur analyse von nukleinsäuregemischen und verfahren zu deren konstruktion - Google Patents
Sonden, bibliotheken und kits zur analyse von nukleinsäuregemischen und verfahren zu deren konstruktionInfo
- Publication number
- ATE553216T1 ATE553216T1 AT04738926T AT04738926T ATE553216T1 AT E553216 T1 ATE553216 T1 AT E553216T1 AT 04738926 T AT04738926 T AT 04738926T AT 04738926 T AT04738926 T AT 04738926T AT E553216 T1 ATE553216 T1 AT E553216T1
- Authority
- AT
- Austria
- Prior art keywords
- nucleic acid
- methods
- kits
- libraries
- probe
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 108020004707 nucleic acids Proteins 0.000 title abstract 3
- 150000007523 nucleic acids Chemical class 0.000 title abstract 3
- 102000039446 nucleic acids Human genes 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 2
- 239000000523 sample Substances 0.000 title abstract 2
- 238000010276 construction Methods 0.000 title 1
- 108020004711 Nucleic Acid Probes Proteins 0.000 abstract 3
- 239000002853 nucleic acid probe Substances 0.000 abstract 3
- 238000001514 detection method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
- G16B25/20—Polymerase chain reaction [PCR]; Primer or probe design; Probe optimisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1065—Preparation or screening of tagged libraries, e.g. tagged microorganisms by STM-mutagenesis, tagged polynucleotides, gene tags
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Computational Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Theoretical Computer Science (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Evolutionary Biology (AREA)
- Medical Informatics (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Crystallography & Structural Chemistry (AREA)
- Plant Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200300933 | 2003-06-20 | ||
| DKPA200301066 | 2003-07-12 | ||
| DKPA200400242 | 2004-02-17 | ||
| DKPA200400353 | 2004-03-01 | ||
| US54934604P | 2004-03-02 | 2004-03-02 | |
| PCT/DK2004/000429 WO2004113563A2 (en) | 2003-06-20 | 2004-06-18 | Probes, libraries and kits for analysis of mixtures of nucleic acids and methods for constructing the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE553216T1 true ATE553216T1 (de) | 2012-04-15 |
Family
ID=45935360
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04738926T ATE553216T1 (de) | 2003-06-20 | 2004-06-18 | Sonden, bibliotheken und kits zur analyse von nukleinsäuregemischen und verfahren zu deren konstruktion |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US20050089889A1 (de) |
| CN (1) | CN1833034B (de) |
| AT (1) | ATE553216T1 (de) |
| DK (1) | DK1639130T3 (de) |
| ES (1) | ES2385828T3 (de) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060166238A1 (en) * | 2004-12-22 | 2006-07-27 | Ramsing Niels B | Probes, libraries and kits for analysis of mixtures of nucleic acids and methods for constructing the same |
| US20070067110A1 (en) * | 2005-09-21 | 2007-03-22 | Nelson Charles F Iii | Generation of negative controls for arrays |
| WO2007136834A2 (en) * | 2006-05-19 | 2007-11-29 | Codon Devices, Inc. | Combined extension and ligation for nucleic acid assembly |
| US8053191B2 (en) * | 2006-08-31 | 2011-11-08 | Westend Asset Clearinghouse Company, Llc | Iterative nucleic acid assembly using activation of vector-encoded traits |
| WO2009100449A1 (en) * | 2008-02-08 | 2009-08-13 | Fluidigm Corporation | Dynamic array assay methods |
| CN101659952B (zh) * | 2009-07-14 | 2012-07-18 | 上海之江生物科技有限公司 | 锁核酸和小沟结合物共修饰核酸片段 |
| CN102409408B (zh) * | 2010-09-21 | 2013-08-07 | 深圳华大基因科技服务有限公司 | 一种利用微量基因组dna进行全基因组甲基化位点精确检测的方法 |
| CN102409043B (zh) * | 2010-09-21 | 2013-12-04 | 深圳华大基因科技服务有限公司 | 高通量低成本Fosmid文库构建的方法及其所使用标签和标签接头 |
| US10457935B2 (en) | 2010-11-12 | 2019-10-29 | Gen9, Inc. | Protein arrays and methods of using and making the same |
| WO2012078312A2 (en) | 2010-11-12 | 2012-06-14 | Gen9, Inc. | Methods and devices for nucleic acids synthesis |
| EP2748318B1 (de) | 2011-08-26 | 2015-11-04 | Gen9, Inc. | Zusammensetzungen und verfahren für hochqualitative anordnung von nukleinsäuren |
| US9150853B2 (en) | 2012-03-21 | 2015-10-06 | Gen9, Inc. | Methods for screening proteins using DNA encoded chemical libraries as templates for enzyme catalysis |
| CN104603286B (zh) | 2012-04-24 | 2020-07-31 | Gen9股份有限公司 | 在体外克隆中分选核酸和多重制备物的方法 |
| CN104685116A (zh) | 2012-06-25 | 2015-06-03 | Gen9股份有限公司 | 用于核酸组装和高通量测序的方法 |
| CN103484458A (zh) * | 2013-10-10 | 2014-01-01 | 东南大学 | 一种含通用碱基寡核苷酸序列及其在dna杂交分析中的应用 |
| EP3227476B1 (de) * | 2014-12-02 | 2021-02-24 | Tribiotica Llc | Verfahren und kits für theranostische anwendungen |
| CN105297145B (zh) * | 2015-11-06 | 2019-03-08 | 艾吉泰康生物科技(北京)有限公司 | 一种制备基因dna探针文库的方法和试剂盒 |
| CN115287335A (zh) * | 2015-11-16 | 2022-11-04 | 雷瑞生物传感器有限责任公司 | 鉴别并区分遗传样品的系统及方法 |
| JP6685138B2 (ja) * | 2016-01-27 | 2020-04-22 | シスメックス株式会社 | 核酸増幅の精度管理方法、精度管理用試薬およびその試薬キット |
| WO2018194342A2 (en) * | 2017-04-17 | 2018-10-25 | Seegene, Inc. . | Methods for preparing optimal combination of oligonucleotides |
| EP3931353A4 (de) | 2019-03-01 | 2022-11-16 | Revere Biosensors, LLC | Systeme und verfahren zur trennung von decodierten arrays |
| CN112480242B (zh) * | 2020-12-04 | 2023-06-06 | 中国人民解放军陆军军医大学 | Spink7蛋白在制备预防和/或治疗溃疡性结肠炎的药物中的应用 |
| CN112402592B (zh) * | 2020-12-04 | 2023-06-02 | 中国人民解放军陆军军医大学 | Spink7蛋白在制备促进过度炎症创面愈合的药物中的应用 |
| CN113322254B (zh) * | 2021-01-06 | 2022-05-20 | 南京诺唯赞生物科技股份有限公司 | 多靶点蛋白质-dna相互作用的研究方法和工具 |
| US20220229819A1 (en) * | 2021-01-21 | 2022-07-21 | Applied Materials, Inc. | Methods, mediums, and systems for configuring a dna/rna target probe design |
| CN113699155B (zh) * | 2021-10-29 | 2022-02-11 | 和元生物技术(上海)股份有限公司 | 一种CuO突变体及其应用 |
| CA3261942A1 (en) * | 2022-08-01 | 2024-02-08 | Idexx Laboratories, Inc. | FRACTIONAL ABUNDANCE DOSES OF HUMAN MOUSE |
| CN115927590A (zh) * | 2022-10-12 | 2023-04-07 | 中南大学 | CircRNA_0085439在筛选药物和生产诊断试剂盒中的用途 |
| CN116072219A (zh) * | 2022-12-30 | 2023-05-05 | 深圳吉因加医学检验实验室 | 探针设计方法及其装置 |
| CN118109591A (zh) * | 2024-03-11 | 2024-05-31 | 宁波市临床病理诊断中心 | 一种cstf3-ret融合基因及其检测引物和应用 |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3687808A (en) * | 1969-08-14 | 1972-08-29 | Univ Leland Stanford Junior | Synthetic polynucleotides |
| US4889818A (en) * | 1986-08-22 | 1989-12-26 | Cetus Corporation | Purified thermostable enzyme |
| US5432272A (en) * | 1990-10-09 | 1995-07-11 | Benner; Steven A. | Method for incorporating into a DNA or RNA oligonucleotide using nucleotides bearing heterocyclic bases |
| US6582908B2 (en) * | 1990-12-06 | 2003-06-24 | Affymetrix, Inc. | Oligonucleotides |
| CN1066519A (zh) * | 1991-05-03 | 1992-11-25 | 上海工业大学 | 微机硬盘写保护卡 |
| US5912340A (en) | 1995-10-04 | 1999-06-15 | Epoch Pharmaceuticals, Inc. | Selective binding complementary oligonucleotides |
| ATE232880T1 (de) * | 1996-11-18 | 2003-03-15 | Takeshi Imanishi | Neue nucleotidanaloga |
| JPH10234381A (ja) * | 1997-02-28 | 1998-09-08 | Shinkinrui Kinou Kaihatsu Kenkyusho:Kk | リゾクトニア属菌検出用の核酸配列 |
| JP3756313B2 (ja) | 1997-03-07 | 2006-03-15 | 武 今西 | 新規ビシクロヌクレオシド及びオリゴヌクレオチド類縁体 |
| DE69829760T3 (de) | 1997-09-12 | 2016-04-14 | Exiqon A/S | Bi- und tri-zyklische - nukleosid, nukleotid und oligonukleotid-analoga |
| US6794499B2 (en) * | 1997-09-12 | 2004-09-21 | Exiqon A/S | Oligonucleotide analogues |
| US7572582B2 (en) * | 1997-09-12 | 2009-08-11 | Exiqon A/S | Oligonucleotide analogues |
| DE69942444D1 (de) * | 1998-02-04 | 2010-07-15 | Life Technologies Corp | Bestimmung des genotyps eines amplifikationsproduktes an mehreren allelen stellen |
| US6322976B1 (en) * | 1998-05-28 | 2001-11-27 | Medical Research Council | Compositions and methods of disease diagnosis and therapy |
| WO1999065928A2 (en) * | 1998-06-19 | 1999-12-23 | Genzyme Corporation | Polynucleotide population isolated from non-metastatic and metastatic breast tumor tissues |
| US7071324B2 (en) * | 1998-10-13 | 2006-07-04 | Brown University Research Foundation | Systems and methods for sequencing by hybridization |
| KR100573231B1 (ko) | 1999-02-12 | 2006-04-24 | 상꾜 가부시키가이샤 | 신규 뉴클레오시드 및 올리고뉴클레오티드 유사체 |
| HK1048639A1 (zh) | 1999-03-18 | 2003-04-11 | 埃克西库恩公司 | 木-lna类似物 |
| US7084125B2 (en) * | 1999-03-18 | 2006-08-01 | Exiqon A/S | Xylo-LNA analogues |
| US6734291B2 (en) * | 1999-03-24 | 2004-05-11 | Exiqon A/S | Synthesis of [2.2.1]bicyclo nucleosides |
| AU3418800A (en) | 1999-03-24 | 2000-10-09 | Exiqon A/S | Improved synthesis of (2.2.1)bicyclo nucleosides |
| AU776362B2 (en) | 1999-05-04 | 2004-09-09 | Roche Innovation Center Copenhagen A/S | L-ribo-LNA analogues |
| WO2001000641A1 (fr) | 1999-06-25 | 2001-01-04 | Sankyo Company, Limited | Nouveaux dérivés de bicyclonucléoside |
| EP1072679A3 (de) | 1999-07-20 | 2002-07-31 | Agilent Technologies, Inc. (a Delaware corporation) | Methode zur Herstelung von Nucleinsäuremolekülen mit einer reduzierten Sekundärstruktur |
| JP4151751B2 (ja) | 1999-07-22 | 2008-09-17 | 第一三共株式会社 | 新規ビシクロヌクレオシド類縁体 |
| US6579680B2 (en) * | 2000-02-28 | 2003-06-17 | Corning Incorporated | Method for label-free detection of hybridized DNA targets |
| WO2002010449A2 (en) | 2000-07-28 | 2002-02-07 | Compugen Inc. | Oligonucleotide library for detecting rna transcripts and splice variants that populate a transcriptome |
| US20020197630A1 (en) * | 2001-04-12 | 2002-12-26 | Knapp Michael R. | Systems and methods for high throughput genetic analysis |
| JP2002360247A (ja) | 2001-06-13 | 2002-12-17 | Takara Bio Inc | 核酸固定化物 |
| CA2459347C (en) * | 2001-09-04 | 2012-10-09 | Exiqon A/S | Locked nucleic acid (lna) compositions and uses thereof |
| AU2002351077A1 (en) | 2001-11-05 | 2003-05-19 | Exiqon A/S | Oligonucleotides modified with novel alpha-l-rna analogues |
| US7569575B2 (en) * | 2002-05-08 | 2009-08-04 | Santaris Pharma A/S | Synthesis of locked nucleic acid derivatives |
| AU2003275018B2 (en) * | 2002-09-20 | 2009-10-01 | Integrated Dna Technologies, Inc. | Anthraquinone quencher dyes, their methods of preparation and use |
| US20040219565A1 (en) | 2002-10-21 | 2004-11-04 | Sakari Kauppinen | Oligonucleotides useful for detecting and analyzing nucleic acids of interest |
-
2004
- 2004-06-18 ES ES04738926T patent/ES2385828T3/es not_active Expired - Lifetime
- 2004-06-18 DK DK04738926.7T patent/DK1639130T3/da active
- 2004-06-18 AT AT04738926T patent/ATE553216T1/de active
- 2004-06-18 CN CN200480022775.3A patent/CN1833034B/zh not_active Expired - Lifetime
- 2004-06-18 US US10/871,471 patent/US20050089889A1/en not_active Abandoned
-
2016
- 2016-09-23 US US15/273,917 patent/US11111535B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20050089889A1 (en) | 2005-04-28 |
| US11111535B2 (en) | 2021-09-07 |
| ES2385828T3 (es) | 2012-08-01 |
| DK1639130T3 (da) | 2012-07-09 |
| CN1833034B (zh) | 2014-04-16 |
| US20170081719A1 (en) | 2017-03-23 |
| CN1833034A (zh) | 2006-09-13 |
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