ATE553216T1 - Sonden, bibliotheken und kits zur analyse von nukleinsäuregemischen und verfahren zu deren konstruktion - Google Patents

Sonden, bibliotheken und kits zur analyse von nukleinsäuregemischen und verfahren zu deren konstruktion

Info

Publication number
ATE553216T1
ATE553216T1 AT04738926T AT04738926T ATE553216T1 AT E553216 T1 ATE553216 T1 AT E553216T1 AT 04738926 T AT04738926 T AT 04738926T AT 04738926 T AT04738926 T AT 04738926T AT E553216 T1 ATE553216 T1 AT E553216T1
Authority
AT
Austria
Prior art keywords
nucleic acid
methods
kits
libraries
probe
Prior art date
Application number
AT04738926T
Other languages
English (en)
Inventor
Niels Ramsing
Peter Mouritzen
Soeren Echwald
Niels Tolstrup
Original Assignee
Exiqon As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Exiqon As filed Critical Exiqon As
Priority claimed from PCT/DK2004/000429 external-priority patent/WO2004113563A2/en
Application granted granted Critical
Publication of ATE553216T1 publication Critical patent/ATE553216T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/20—Polymerase chain reaction [PCR]; Primer or probe design; Probe optimisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1065—Preparation or screening of tagged libraries, e.g. tagged microorganisms by STM-mutagenesis, tagged polynucleotides, gene tags
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Medical Informatics (AREA)
  • Evolutionary Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT04738926T 2003-06-20 2004-06-18 Sonden, bibliotheken und kits zur analyse von nukleinsäuregemischen und verfahren zu deren konstruktion ATE553216T1 (de)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
DKPA200300933 2003-06-20
DKPA200301066 2003-07-12
DKPA200400242 2004-02-17
DKPA200400353 2004-03-01
US54934604P 2004-03-02 2004-03-02
PCT/DK2004/000429 WO2004113563A2 (en) 2003-06-20 2004-06-18 Probes, libraries and kits for analysis of mixtures of nucleic acids and methods for constructing the same

Publications (1)

Publication Number Publication Date
ATE553216T1 true ATE553216T1 (de) 2012-04-15

Family

ID=45935360

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04738926T ATE553216T1 (de) 2003-06-20 2004-06-18 Sonden, bibliotheken und kits zur analyse von nukleinsäuregemischen und verfahren zu deren konstruktion

Country Status (5)

Country Link
US (2) US20050089889A1 (de)
CN (1) CN1833034B (de)
AT (1) ATE553216T1 (de)
DK (1) DK1639130T3 (de)
ES (1) ES2385828T3 (de)

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CN102409043B (zh) * 2010-09-21 2013-12-04 深圳华大基因科技服务有限公司 高通量低成本Fosmid文库构建的方法及其所使用标签和标签接头
CN102409408B (zh) * 2010-09-21 2013-08-07 深圳华大基因科技服务有限公司 一种利用微量基因组dna进行全基因组甲基化位点精确检测的方法
CA2817697C (en) 2010-11-12 2021-11-16 Gen9, Inc. Methods and devices for nucleic acids synthesis
WO2012064975A1 (en) 2010-11-12 2012-05-18 Gen9, Inc. Protein arrays and methods of using and making the same
JP2014526899A (ja) 2011-08-26 2014-10-09 ジェン９・インコーポレイテッド 核酸の高忠実度アセンブリのための組成物および方法
US9150853B2 (en) 2012-03-21 2015-10-06 Gen9, Inc. Methods for screening proteins using DNA encoded chemical libraries as templates for enzyme catalysis
CA2871505C (en) 2012-04-24 2021-10-12 Gen9, Inc. Methods for sorting nucleic acids and multiplexed preparative in vitro cloning
WO2014004393A1 (en) 2012-06-25 2014-01-03 Gen9, Inc. Methods for nucleic acid assembly and high throughput sequencing
JP6395718B2 (ja) * 2012-11-19 2018-09-26 アプトン バイオシステムズ インコーポレイテッド 単一分子検出を用いた分子分析物のデジタル分析の方法
CN103484458A (zh) * 2013-10-10 2014-01-01 东南大学 一种含通用碱基寡核苷酸序列及其在dna杂交分析中的应用
EP3227476B1 (de) * 2014-12-02 2021-02-24 Tribiotica Llc Verfahren und kits für theranostische anwendungen
CN105297145B (zh) * 2015-11-06 2019-03-08 艾吉泰康生物科技(北京)有限公司 一种制备基因dna探针文库的方法和试剂盒
US11725233B2 (en) * 2015-11-16 2023-08-15 Revere Biosensors, Llc Systems and methods for identifying and distinguishing genetic samples
JP6685138B2 (ja) * 2016-01-27 2020-04-22 シスメックス株式会社 核酸増幅の精度管理方法、精度管理用試薬およびその試薬キット
US11961590B2 (en) 2017-04-17 2024-04-16 Seegene, Inc. Methods for preparing optimal combination of oligonucleotides
US12565676B2 (en) 2019-03-01 2026-03-03 Revere Biosensors, Llc Systems and methods for separating decoded arrays
CN112402592B (zh) * 2020-12-04 2023-06-02 中国人民解放军陆军军医大学 Spink7蛋白在制备促进过度炎症创面愈合的药物中的应用
CN112480242B (zh) * 2020-12-04 2023-06-06 中国人民解放军陆军军医大学 Spink7蛋白在制备预防和/或治疗溃疡性结肠炎的药物中的应用
CN113322254B (zh) * 2021-01-06 2022-05-20 南京诺唯赞生物科技股份有限公司 多靶点蛋白质-dna相互作用的研究方法和工具
US20220229819A1 (en) * 2021-01-21 2022-07-21 Applied Materials, Inc. Methods, mediums, and systems for configuring a dna/rna target probe design
CN113699155B (zh) * 2021-10-29 2022-02-11 和元生物技术（上海）股份有限公司 一种CuO突变体及其应用
EP4565716A4 (de) * 2022-08-01 2026-07-15 Idexx Lab Inc Fraktionelle häufigkeitstests der menschlichen maus
CN115927590A (zh) * 2022-10-12 2023-04-07 中南大学 CircRNA_0085439在筛选药物和生产诊断试剂盒中的用途
CN116072219B (zh) * 2022-12-30 2026-08-07 深圳吉因加生物科技有限公司 探针设计方法及其装置
CN118109591A (zh) * 2024-03-11 2024-05-31 宁波市临床病理诊断中心 一种cstf3-ret融合基因及其检测引物和应用

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Also Published As

Publication number Publication date
CN1833034A (zh) 2006-09-13
US11111535B2 (en) 2021-09-07
US20170081719A1 (en) 2017-03-23
ES2385828T3 (es) 2012-08-01
DK1639130T3 (da) 2012-07-09
CN1833034B (zh) 2014-04-16
US20050089889A1 (en) 2005-04-28

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