ATE331739T1 - Polyanionische polymere mit verbesserter fusogenfähigkeit - Google Patents
Polyanionische polymere mit verbesserter fusogenfähigkeitInfo
- Publication number
- ATE331739T1 ATE331739T1 AT99920057T AT99920057T ATE331739T1 AT E331739 T1 ATE331739 T1 AT E331739T1 AT 99920057 T AT99920057 T AT 99920057T AT 99920057 T AT99920057 T AT 99920057T AT E331739 T1 ATE331739 T1 AT E331739T1
- Authority
- AT
- Austria
- Prior art keywords
- fusogen
- capacity
- improved
- peaa
- lipo
- Prior art date
Links
- 229920000447 polyanionic polymer Polymers 0.000 title 1
- 239000002502 liposome Substances 0.000 abstract 2
- -1 poly(2-ethylacrylic acid) Polymers 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 230000000799 fusogenic effect Effects 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 229920000867 polyelectrolyte Polymers 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/12—Hydrolysis
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups
- C08F8/32—Introducing nitrogen atoms or nitrogen-containing groups by reaction with amines
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8329498P | 1998-04-28 | 1998-04-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE331739T1 true ATE331739T1 (de) | 2006-07-15 |
Family
ID=22177405
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99920057T ATE331739T1 (de) | 1998-04-28 | 1999-04-27 | Polyanionische polymere mit verbesserter fusogenfähigkeit |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1100834B1 (de) |
| AT (1) | ATE331739T1 (de) |
| AU (1) | AU3764099A (de) |
| DE (1) | DE69932164D1 (de) |
| WO (1) | WO1999055743A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6727230B1 (en) | 1994-03-25 | 2004-04-27 | Coley Pharmaceutical Group, Inc. | Immune stimulation by phosphorothioate oligonucleotide analogs |
| US6207646B1 (en) | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| US6406705B1 (en) | 1997-03-10 | 2002-06-18 | University Of Iowa Research Foundation | Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant |
| SI1077722T1 (sl) | 1998-05-22 | 2007-02-28 | Ottawa Health Research Inst | Metode in produkti za induciranje sluznicne imunosti |
| DE60008234T2 (de) * | 1999-04-29 | 2004-12-30 | Alza Corp., Mountain View | Liposomenzusammensetzungen zur verbesserten wirkstoffzurückhaltung |
| EP1320553A4 (de) * | 2000-08-23 | 2006-03-15 | Phairson Medical Inc | Neue polymerzusammensetzung |
| JP4361789B2 (ja) | 2001-08-14 | 2009-11-11 | ヴァルダーム・アンパルトセルスカブ | 体表の過剰増殖疾患の処置 |
| CA2502015A1 (en) | 2002-12-11 | 2004-06-24 | Coley Pharmaceutical Group, Inc. | 5' cpg nucleic acids and methods of use |
| US12297285B2 (en) | 2022-06-24 | 2025-05-13 | Orna Therapeutics, Inc. | Circular RNA encoding chimeric antigen receptors targeting BCMA |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4118554A (en) * | 1977-07-25 | 1978-10-03 | Monsanto Company | Aggregated polyelectrolytes |
| US5149543A (en) * | 1990-10-05 | 1992-09-22 | Massachusetts Institute Of Technology | Ionically cross-linked polymeric microcapsules |
| EP0554407A1 (de) * | 1990-10-26 | 1993-08-11 | Genta Incorporated | Nichtaromatische organische polymerreagentien für die festphasensynthese von oligomeren |
| US5180782A (en) * | 1991-02-19 | 1993-01-19 | Basf Corporation | Compatible polyamide-acrylic compositions |
| JP3708567B2 (ja) * | 1994-07-20 | 2005-10-19 | 日清紡績株式会社 | 生物学的に活性な物質を固定するための方法 |
-
1999
- 1999-04-27 WO PCT/US1999/009076 patent/WO1999055743A1/en not_active Ceased
- 1999-04-27 AU AU37640/99A patent/AU3764099A/en not_active Abandoned
- 1999-04-27 AT AT99920057T patent/ATE331739T1/de not_active IP Right Cessation
- 1999-04-27 EP EP99920057A patent/EP1100834B1/de not_active Expired - Lifetime
- 1999-04-27 DE DE69932164T patent/DE69932164D1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1100834B1 (de) | 2006-06-28 |
| WO1999055743A9 (en) | 2000-10-05 |
| AU3764099A (en) | 1999-11-16 |
| DE69932164D1 (de) | 2006-08-10 |
| EP1100834A1 (de) | 2001-05-23 |
| WO1999055743A1 (en) | 1999-11-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |