TR200201089T2 - Dipiridamol veya mopidamolün fibrine bağlı mikrodolaşım bozukluklarının tedavisi - Google Patents
Dipiridamol veya mopidamolün fibrine bağlı mikrodolaşım bozukluklarının tedavisiInfo
- Publication number
- TR200201089T2 TR200201089T2 TR2002/01089T TR200201089T TR200201089T2 TR 200201089 T2 TR200201089 T2 TR 200201089T2 TR 2002/01089 T TR2002/01089 T TR 2002/01089T TR 200201089 T TR200201089 T TR 200201089T TR 200201089 T2 TR200201089 T2 TR 200201089T2
- Authority
- TR
- Turkey
- Prior art keywords
- fibrin
- diseases
- microcirculatory
- mopidamol
- dipyridamole
- Prior art date
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
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- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
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- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
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- Hematology (AREA)
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- Endocrinology (AREA)
- Transplantation (AREA)
- Gastroenterology & Hepatology (AREA)
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Abstract
Bu bulusta, insan olan veya olmayan bir hayvan vücudunda fibrine bagli mikrodolasim hastaliklarini, örnegin metabolik hastaliklar, inflamatuar tepkimeler veya otobagisiklik hastaliklari gibi fibrine bagli mikrodolasim hastaliklari ve bunlardan baska periferal mikrodolasim bozukluklari veya artan hücre fragmantasyonu ile baglantili mikrodolasim bozukluklarini tedavi etmek için bir yöntem açiklanmistir ki söz konusu yöntem böyle bir tedaviye ihtiyaç duyan insan olan veya olmayan bir hayvan vücuduna, dipiridamol, mopidamol ve bunlarin farmasötik açidan kabul edilebilir tuzlarindan seçilen bir pirimido-pirimidin içeren bir farmasötik kompozisyondan etkili bir miktar vermekten meydana gelir. ayrica bu bulusta söz konusu pirimido-pirimidinin denk gelen bir farmasötik kompozisyonun üretimi için kullanimi tarif edilir.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99121121A EP1093814A1 (en) | 1999-10-22 | 1999-10-22 | Use of dipyridamole or mopidamol in the manufacture of a medicament for the treatment and prevention of fibrin-dependent microcirculation disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200201089T2 true TR200201089T2 (tr) | 2002-09-23 |
Family
ID=8239263
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2002/01089T TR200201089T2 (tr) | 1999-10-22 | 2000-10-14 | Dipiridamol veya mopidamolün fibrine bağlı mikrodolaşım bozukluklarının tedavisi |
Country Status (27)
| Country | Link |
|---|---|
| US (2) | US20030149058A1 (tr) |
| EP (2) | EP1093814A1 (tr) |
| JP (1) | JP2003512431A (tr) |
| KR (1) | KR20020040901A (tr) |
| CN (2) | CN100411620C (tr) |
| AR (1) | AR026197A1 (tr) |
| AU (1) | AU784124B2 (tr) |
| BG (1) | BG106609A (tr) |
| BR (1) | BR0014946A (tr) |
| CA (1) | CA2387486C (tr) |
| CZ (1) | CZ20021487A3 (tr) |
| EA (1) | EA200200448A1 (tr) |
| EE (1) | EE200200214A (tr) |
| HK (1) | HK1048597A1 (tr) |
| HR (1) | HRP20020342A2 (tr) |
| HU (1) | HUP0203249A3 (tr) |
| IL (1) | IL148974A0 (tr) |
| MX (1) | MXPA02003901A (tr) |
| NO (1) | NO20021784D0 (tr) |
| NZ (1) | NZ518525A (tr) |
| PE (1) | PE20010747A1 (tr) |
| PL (1) | PL354591A1 (tr) |
| SK (1) | SK7112002A3 (tr) |
| TR (1) | TR200201089T2 (tr) |
| WO (1) | WO2001030353A1 (tr) |
| YU (1) | YU30002A (tr) |
| ZA (1) | ZA200203156B (tr) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1093814A1 (en) * | 1999-10-22 | 2001-04-25 | Boehringer Ingelheim Pharma KG | Use of dipyridamole or mopidamol in the manufacture of a medicament for the treatment and prevention of fibrin-dependent microcirculation disorders |
| DE10119680A1 (de) * | 2001-04-20 | 2002-11-14 | Boehringer Ingelheim Pharma | Verwendung von Radikalfänger-Verbindungen zur Behandlung und Verhinderung von no-abhängigen Störungen der Mikrozirkulation |
| US7064130B2 (en) * | 2001-04-20 | 2006-06-20 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Use of radical-scavenging compounds for treatment and prevention of NO-dependent microcirculation disorders |
| BR0213100A (pt) | 2001-10-05 | 2004-11-30 | Combinatorx Inc | Combinações para o tratamento de distúrbios imuniinflamatórios |
| MY131170A (en) * | 2002-03-28 | 2007-07-31 | Nissan Chemical Ind Ltd | Therapeutic agent for glomerular disease |
| DE10335027A1 (de) * | 2003-07-31 | 2005-02-17 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verwendung von Angiotensin II Rezeptor Antagonisten |
| JP2006516593A (ja) * | 2003-02-07 | 2006-07-06 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Mmp−9依存性疾患の治療及び予防のためのジピリダモール又はモピダモールの使用 |
| DE10306179A1 (de) * | 2003-02-13 | 2004-08-26 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verwendung von Dipyridamol in Kombination mit Acetylsalicylsäure und einem Angiotensin II-Antagonisten zur Schlaganfall-Prophylaxe |
| WO2004093881A2 (en) * | 2003-04-24 | 2004-11-04 | Boehringer Ingelheim International Gmbh | Use of dipyridamole or mopidamole for treatment and prevention of thrombo-embolic diseases and disorders caused by excessive formation of thrombin and/or by elevated expression of thrombin receptors |
| JP2005060359A (ja) * | 2003-08-13 | 2005-03-10 | Boehringer Ingelheim Pharma Gmbh & Co Kg | 血管系病態の治療及び予防のためのジピリダモール、アセチルサリチル酸及びアンギオテンシンii拮抗薬の使用 |
| TW200517114A (en) * | 2003-10-15 | 2005-06-01 | Combinatorx Inc | Methods and reagents for the treatment of immunoinflammatory disorders |
| AU2005245271A1 (en) | 2004-05-13 | 2005-12-01 | Boehringer Ingelheim International Gmbh | Use of dipyridamole for treatment of resistance to platelet inhibitors |
| WO2005118166A2 (en) | 2004-06-04 | 2005-12-15 | Teva Pharmaceutical Industries, Ltd. | Pharmaceutical composition containing irbesartan |
| DE602006000819T2 (de) * | 2006-02-09 | 2009-04-09 | Teva Pharmaceutical Industries Ltd. | Dipyridamol enthaltende Zusammensetzungen mit verlängerter Freisetzung und Verfahren zu deren Herstellung |
| US20100062066A1 (en) * | 2006-11-14 | 2010-03-11 | Acusphere, Inc | Formulations of Tetrahydropyridine Antiplatelet Agents for Parenteral or Oral Administration |
| CN105473133A (zh) * | 2013-04-30 | 2016-04-06 | 欧缇托匹克公司 | 干粉制剂及使用方法 |
| TW201503900A (zh) * | 2013-07-29 | 2015-02-01 | ren-zheng Lin | 增強治療急性中風之抗血小板藥物之遞送方法及其組合物 |
| WO2016119701A1 (en) | 2015-01-28 | 2016-08-04 | Realinn Life Science Limited | COMPOUNDS FOR ENHANCING PPARγ EXPRESSION AND NUCLEAR TRANSLOCATION AND THERAPEUTIC USE THEREOF |
| KR101736832B1 (ko) | 2017-02-28 | 2017-05-17 | 초당약품공업 주식회사 | 디피리다몰을 유효 성분으로 함유하는 신장 질환 치료용 의약 조성물 |
| CN111346228B (zh) * | 2018-12-21 | 2022-01-14 | 广州市妇女儿童医疗中心 | 胃肠道疾病的免疫机制及治疗药物 |
| CN114432451B (zh) * | 2018-12-21 | 2024-02-09 | 广州市妇女儿童医疗中心 | 胃肠道疾病的免疫机制及治疗药物 |
| GB202006960D0 (en) * | 2020-05-12 | 2020-06-24 | Aplagon Oy | Therapeutic |
| CN118477044A (zh) * | 2023-02-13 | 2024-08-13 | 智泽童康(广州)生物科技有限公司 | 一种双嘧达莫的矫味组合物、干混悬剂及其应用 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3031450A (en) * | 1959-04-30 | 1962-04-24 | Thomae Gmbh Dr K | Substituted pyrimido-[5, 4-d]-pyrimidines |
| DE2735830A1 (de) * | 1977-08-09 | 1979-03-01 | Thomae Gmbh Dr K | Antithrombotische arzneimittelkombination und verfahren zu ihrer herstellung |
| DE3000979A1 (de) * | 1980-01-12 | 1981-07-23 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue dipyridamol-retardformen und verfahren zu ihrer herstellung |
| DE3124090A1 (de) * | 1981-06-19 | 1983-01-05 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue orale dipyridamolformen |
| DE3237575A1 (de) * | 1982-10-09 | 1984-04-12 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue orale mopidamolformen |
| JPS6153271A (ja) * | 1984-08-24 | 1986-03-17 | Kaken Pharmaceut Co Ltd | ローダニン誘導体 |
| EP0169465B1 (de) * | 1984-07-21 | 1990-02-28 | Hoechst Aktiengesellschaft | Kombinationspräparat aus Pyrimido-pyrimidinen und O-Acetylsalicylsäure bzw. deren pharmakologisch verträglichen Salzen und dessen Verwendung |
| DE3627423A1 (de) * | 1986-08-13 | 1988-02-18 | Thomae Gmbh Dr K | Arzneimittel enthaltend dipyridamol oder mopidamol und o-acetylsalicylsaeure bzw. deren physiologisch vertraegliche salze, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung der thrombusbildung |
| US5242921A (en) * | 1988-04-27 | 1993-09-07 | Yale University | Compositions and methods for treating cutaneous hyperproliferative disorders |
| SU1685450A1 (ru) * | 1989-03-10 | 1991-10-23 | Московский медицинский стоматологический институт им.Н.А.Семашко | Способ лечени скаленус-синдрома при шейном остеохондрозе |
| IT1239064B (it) * | 1990-05-14 | 1993-09-20 | Fidia Spa | Uso terapeutico del dipiridamolo |
| US5639482A (en) * | 1993-11-10 | 1997-06-17 | Crary; Ely J. | Composition for control and prevention of diabetic retinopathy |
| CN1111985A (zh) * | 1994-05-06 | 1995-11-22 | 王志刚 | 阿司匹林与潘生丁复方多层片的制备方法 |
| US5498613A (en) * | 1994-06-07 | 1996-03-12 | The University Of Southern California | Dipyridamole and analogs thereof in preventing adhesion formation |
| US5968983A (en) * | 1994-10-05 | 1999-10-19 | Nitrosystems, Inc | Method and formulation for treating vascular disease |
| US5620409A (en) * | 1995-09-15 | 1997-04-15 | The Research Foundation Of State University Of New York | Method for inhibiting clot formation |
| CN1152436A (zh) * | 1995-12-22 | 1997-06-25 | 王介明 | 一种治疗缺血性脑血管病和脑血栓的康复液及其制法 |
| CA2293429A1 (en) * | 1997-06-05 | 1998-12-10 | Eli Lilly And Company | Methods for treating thrombotic disorders |
| CN1108798C (zh) * | 1999-01-26 | 2003-05-21 | 广东药学院 | 一种治疗、预防血栓形成及中风的复方制剂及其制备方法 |
| AU779991B2 (en) * | 1999-08-10 | 2005-02-24 | Board Of Regents, The University Of Texas System | Method for increasing optic nerve, choroidal and retinal blood flow to facilitate the preservation of sight |
| EP1093814A1 (en) * | 1999-10-22 | 2001-04-25 | Boehringer Ingelheim Pharma KG | Use of dipyridamole or mopidamol in the manufacture of a medicament for the treatment and prevention of fibrin-dependent microcirculation disorders |
| DE10011482B4 (de) * | 2000-03-09 | 2004-06-09 | Fresenius Hemocare Gmbh | Verfahren zum Herstellen eines Adsorbens zum Absenken der Konzentration von Fibrinogen und/oder Fibrin, Adsorbens und Verwendung des Adsorbens zur Herstellung eines Adsorbers |
| US6979462B1 (en) * | 2000-10-03 | 2005-12-27 | Mutual Pharmaceutical Co., Inc. | Stabilization of solid drug formulations |
| US7064130B2 (en) * | 2001-04-20 | 2006-06-20 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Use of radical-scavenging compounds for treatment and prevention of NO-dependent microcirculation disorders |
| US20020187187A1 (en) * | 2001-04-21 | 2002-12-12 | Toshimitsu Ohki | Fast disintegrating meloxicam tablet |
| US7064103B2 (en) * | 2002-01-04 | 2006-06-20 | Becton, Dickinson And Company | Binding protein as biosensors |
| US20030180282A1 (en) * | 2002-03-25 | 2003-09-25 | Victor Serebruany | Method of treatment of thrombotic events |
| JP2006516593A (ja) * | 2003-02-07 | 2006-07-06 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Mmp−9依存性疾患の治療及び予防のためのジピリダモール又はモピダモールの使用 |
| WO2004093881A2 (en) * | 2003-04-24 | 2004-11-04 | Boehringer Ingelheim International Gmbh | Use of dipyridamole or mopidamole for treatment and prevention of thrombo-embolic diseases and disorders caused by excessive formation of thrombin and/or by elevated expression of thrombin receptors |
-
1999
- 1999-10-22 EP EP99121121A patent/EP1093814A1/en not_active Withdrawn
-
2000
- 2000-10-14 JP JP2001532773A patent/JP2003512431A/ja active Pending
- 2000-10-14 PL PL00354591A patent/PL354591A1/xx not_active Application Discontinuation
- 2000-10-14 BR BR0014946-2A patent/BR0014946A/pt not_active IP Right Cessation
- 2000-10-14 CN CNB008146756A patent/CN100411620C/zh not_active Expired - Fee Related
- 2000-10-14 CA CA002387486A patent/CA2387486C/en not_active Expired - Fee Related
- 2000-10-14 IL IL14897400A patent/IL148974A0/xx unknown
- 2000-10-14 TR TR2002/01089T patent/TR200201089T2/tr unknown
- 2000-10-14 HU HU0203249A patent/HUP0203249A3/hu unknown
- 2000-10-14 MX MXPA02003901A patent/MXPA02003901A/es unknown
- 2000-10-14 EP EP00974393A patent/EP1225900A1/en not_active Withdrawn
- 2000-10-14 WO PCT/EP2000/010123 patent/WO2001030353A1/en not_active Ceased
- 2000-10-14 YU YU30002A patent/YU30002A/sh unknown
- 2000-10-14 EE EEP200200214A patent/EE200200214A/xx unknown
- 2000-10-14 AU AU12721/01A patent/AU784124B2/en not_active Ceased
- 2000-10-14 HK HK03100835.6A patent/HK1048597A1/zh unknown
- 2000-10-14 CZ CZ20021487A patent/CZ20021487A3/cs unknown
- 2000-10-14 SK SK711-2002A patent/SK7112002A3/sk not_active Application Discontinuation
- 2000-10-14 NZ NZ518525A patent/NZ518525A/en unknown
- 2000-10-14 CN CNA2005101362547A patent/CN1823780A/zh active Pending
- 2000-10-14 EA EA200200448A patent/EA200200448A1/ru unknown
- 2000-10-14 HR HR20020342A patent/HRP20020342A2/hr not_active Application Discontinuation
- 2000-10-14 KR KR1020027005042A patent/KR20020040901A/ko not_active Ceased
- 2000-10-20 PE PE2000001127A patent/PE20010747A1/es not_active Application Discontinuation
- 2000-10-20 AR ARP000105541A patent/AR026197A1/es unknown
-
2002
- 2002-04-12 BG BG106609A patent/BG106609A/bg unknown
- 2002-04-16 NO NO20021784A patent/NO20021784D0/no not_active Application Discontinuation
- 2002-04-22 ZA ZA200203156A patent/ZA200203156B/xx unknown
-
2003
- 2003-02-27 US US10/376,072 patent/US20030149058A1/en not_active Abandoned
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2007
- 2007-12-18 US US11/958,504 patent/US20080113934A1/en not_active Abandoned
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