ATE331805T1 - Alpha-2,8/2,9-polysialyltransferase - Google Patents
Alpha-2,8/2,9-polysialyltransferaseInfo
- Publication number
- ATE331805T1 ATE331805T1 AT99941028T AT99941028T ATE331805T1 AT E331805 T1 ATE331805 T1 AT E331805T1 AT 99941028 T AT99941028 T AT 99941028T AT 99941028 T AT99941028 T AT 99941028T AT E331805 T1 ATE331805 T1 AT E331805T1
- Authority
- AT
- Austria
- Prior art keywords
- alpha
- coli
- linkages
- neuac
- enzyme
- Prior art date
Links
- 241000588724 Escherichia coli Species 0.000 abstract 5
- 229940060155 neuac Drugs 0.000 abstract 5
- 102000004190 Enzymes Human genes 0.000 abstract 3
- 108090000790 Enzymes Proteins 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 150000004676 glycans Chemical class 0.000 abstract 2
- 229920001282 polysaccharide Polymers 0.000 abstract 2
- 239000005017 polysaccharide Substances 0.000 abstract 2
- SQVRNKJHWKZAKO-PFQGKNLYSA-N N-acetyl-beta-neuraminic acid Chemical compound CC(=O)N[C@@H]1[C@@H](O)C[C@@](O)(C(O)=O)O[C@H]1[C@H](O)[C@H](O)CO SQVRNKJHWKZAKO-PFQGKNLYSA-N 0.000 abstract 1
- 238000005481 NMR spectroscopy Methods 0.000 abstract 1
- 239000000370 acceptor Substances 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 238000004458 analytical method Methods 0.000 abstract 1
- SQVRNKJHWKZAKO-UHFFFAOYSA-N beta-N-Acetyl-D-neuraminic acid Natural products CC(=O)NC1C(O)CC(O)(C(O)=O)OC1C(O)C(O)CO SQVRNKJHWKZAKO-UHFFFAOYSA-N 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 150000001720 carbohydrates Chemical class 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- 230000009089 cytolysis Effects 0.000 abstract 1
- 238000006911 enzymatic reaction Methods 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 150000002270 gangliosides Chemical class 0.000 abstract 1
- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 238000004949 mass spectrometry Methods 0.000 abstract 1
- 230000000379 polymerizing effect Effects 0.000 abstract 1
- 239000000047 product Substances 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 238000002415 sodium dodecyl sulfate polyacrylamide gel electrophoresis Methods 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
- 239000006228 supernatant Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 238000005199 ultracentrifugation Methods 0.000 abstract 1
- 238000001262 western blot Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1081—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/18—Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
- Bipolar Transistors (AREA)
- Enzymes And Modification Thereof (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Shaping Of Tube Ends By Bending Or Straightening (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9600398P | 1998-08-10 | 1998-08-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE331805T1 true ATE331805T1 (de) | 2006-07-15 |
Family
ID=22254606
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99941028T ATE331805T1 (de) | 1998-08-10 | 1999-08-10 | Alpha-2,8/2,9-polysialyltransferase |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1105515B1 (de) |
| AT (1) | ATE331805T1 (de) |
| AU (1) | AU5475899A (de) |
| CA (1) | CA2339173A1 (de) |
| DE (1) | DE69932166T2 (de) |
| ES (1) | ES2267285T3 (de) |
| WO (1) | WO2000009736A1 (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2002323358A1 (en) * | 2001-08-24 | 2003-03-10 | Karoliska Innovations Ab | Methods for preparing purified prostaglandin e synthase |
-
1999
- 1999-08-10 DE DE69932166T patent/DE69932166T2/de not_active Expired - Lifetime
- 1999-08-10 AU AU54758/99A patent/AU5475899A/en not_active Abandoned
- 1999-08-10 ES ES99941028T patent/ES2267285T3/es not_active Expired - Lifetime
- 1999-08-10 CA CA002339173A patent/CA2339173A1/en not_active Abandoned
- 1999-08-10 AT AT99941028T patent/ATE331805T1/de not_active IP Right Cessation
- 1999-08-10 WO PCT/US1999/018154 patent/WO2000009736A1/en not_active Ceased
- 1999-08-10 EP EP99941028A patent/EP1105515B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000009736A1 (en) | 2000-02-24 |
| CA2339173A1 (en) | 2000-02-24 |
| EP1105515B1 (de) | 2006-06-28 |
| DE69932166D1 (en) | 2006-08-10 |
| AU5475899A (en) | 2000-03-06 |
| ES2267285T3 (es) | 2007-03-01 |
| EP1105515A1 (de) | 2001-06-13 |
| DE69932166T2 (de) | 2007-05-16 |
| EP1105515A4 (de) | 2002-08-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |