ATE332126T1 - Geschmacksmaskierte pharmazeutische zusammensetzungen - Google Patents

Geschmacksmaskierte pharmazeutische zusammensetzungen

Info

Publication number
ATE332126T1
ATE332126T1 AT98953209T AT98953209T ATE332126T1 AT E332126 T1 ATE332126 T1 AT E332126T1 AT 98953209 T AT98953209 T AT 98953209T AT 98953209 T AT98953209 T AT 98953209T AT E332126 T1 ATE332126 T1 AT E332126T1
Authority
AT
Austria
Prior art keywords
flavor
pharmaceutical compositions
masked pharmaceutical
masked
spheronizing
Prior art date
Application number
AT98953209T
Other languages
English (en)
Inventor
Michael Augello
Ronald S Vladyka Jr
Sheila M Dell
Original Assignee
Scherer Technologies Inc R P
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scherer Technologies Inc R P filed Critical Scherer Technologies Inc R P
Application granted granted Critical
Publication of ATE332126T1 publication Critical patent/ATE332126T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT98953209T 1997-10-03 1998-09-30 Geschmacksmaskierte pharmazeutische zusammensetzungen ATE332126T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/942,962 US5904937A (en) 1997-10-03 1997-10-03 Taste masked pharmaceutical compositions

Publications (1)

Publication Number Publication Date
ATE332126T1 true ATE332126T1 (de) 2006-07-15

Family

ID=25478887

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98953209T ATE332126T1 (de) 1997-10-03 1998-09-30 Geschmacksmaskierte pharmazeutische zusammensetzungen

Country Status (15)

Country Link
US (1) US5904937A (de)
EP (1) EP1027038B1 (de)
JP (2) JP2001518491A (de)
KR (1) KR100563342B1 (de)
CN (1) CN1154481C (de)
AT (1) ATE332126T1 (de)
AU (1) AU1063799A (de)
BR (1) BR9812590B1 (de)
CA (1) CA2303177C (de)
DE (1) DE69835162T2 (de)
DK (1) DK1027038T3 (de)
IL (1) IL135121A (de)
NO (1) NO20001670L (de)
PL (1) PL339568A1 (de)
WO (1) WO1999017748A1 (de)

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IL134701A0 (en) 2000-02-23 2001-04-30 J P M E D Ltd Homogeneous solid matrix containing vegetable proteins
GEP20043285B (en) 2000-03-30 2004-07-26 Bristol Myers Squibb Co Sustained Release Beadlets Containing Stavudine, Method for Their Production, Pharmaceutical Composition Containing the Same and Use Thereof for Treatment Retroviral Infections
EP1252886A1 (de) * 2001-04-27 2002-10-30 Universiteit Gent Pharmazeutische Pelletformulierungen für eine kontrollierte Freisetzung
GB0027357D0 (en) 2000-11-09 2000-12-27 Bradford Particle Design Plc Particle formation methods and their products
US6932861B2 (en) * 2000-11-28 2005-08-23 Fmc Corporation Edible PGA coating composition
CZ20032138A3 (cs) * 2001-02-05 2005-03-16 R. P. Scherer Technologies, Inc. Způsoby a prostředky pro zeslabení chuti farmaceuticky aktivních činidel
EP1404333A1 (de) 2001-07-06 2004-04-07 Endo Pharmaceuticals Inc. Kontrolliert freisetzende formulierungen von oxymorphon
AU2002327418A1 (en) * 2001-08-01 2003-02-17 Bristol-Myers Squibb Company Taste masking composition
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
ES2199061B1 (es) * 2002-06-10 2005-02-16 Laboratorios Vita, S.A. Comprimidos bucodispersables y procedimiento para su obtencion.
US20040037869A1 (en) * 2002-08-16 2004-02-26 Douglas Cleverly Non-animal product containing veterinary formulations
US20040151759A1 (en) * 2002-08-16 2004-08-05 Douglas Cleverly Non-animal product containing veterinary formulations
JP2004107258A (ja) * 2002-09-18 2004-04-08 Ss Pharmaceut Co Ltd 催眠用圧縮成型製剤
WO2004069132A2 (de) * 2003-02-06 2004-08-19 Gebro Pharma Gmbh Pharmazeutische zubereitungen und verfahren zu deren herstellung
JP4643899B2 (ja) * 2003-10-20 2011-03-02 エスエス製薬株式会社 イブプロフェン含有錠剤およびその製造方法
CA2618966C (en) * 2005-08-10 2014-05-13 Shionogi & Co., Ltd. Bitterness-reducing agent
US20070036859A1 (en) * 2005-08-11 2007-02-15 Perry Ronald L Sustained release antihistamine and decongestant composition
JP2007131561A (ja) * 2005-11-09 2007-05-31 Ss Pharmaceut Co Ltd 経口固形製剤及びその製造法
US20070286903A1 (en) * 2006-06-13 2007-12-13 Becicka Brian T Composition and method for taste masking
CA2652981C (en) * 2006-10-10 2012-05-01 Penwest Pharmaceuticals Co. Robust sustained release formulations
EP1935405A1 (de) * 2006-12-22 2008-06-25 LEK Pharmaceuticals D.D. Im Mund zerfallende Tabletten
CN102202654B (zh) * 2008-09-04 2014-07-30 法纳姆公司 可咀嚼的缓释制剂
US9925282B2 (en) 2009-01-29 2018-03-27 The General Hospital Corporation Cromolyn derivatives and related methods of imaging and treatment
AU2010233917B2 (en) 2009-04-02 2015-07-02 Merck Serono S.A. Dihydroorotate dehydrogenase inhibitors
WO2011087705A2 (en) * 2009-12-22 2011-07-21 Fmc Corporation Fine particle croscarmellose and uses thereof
JP2013539772A (ja) * 2010-10-12 2013-10-28 バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 非澱粉を基にしたソフトチュアブル
MX350838B (es) 2011-02-11 2017-09-18 Grain Proc Corporation * Composicion de sal.
EP2911664B1 (de) 2012-10-25 2019-05-08 The General Hospital Corporation Kombinationstherapien zur behandlung von morbus alzheimer und verwandten erkrankungen
RS57962B1 (sr) 2013-02-25 2019-01-31 Aurigene Discovery Tech Ltd Derivati trisupstituisanog benzotriazola kao inhibitori dihidroorotat oksigenaze
CN105451771B (zh) * 2013-03-15 2020-05-19 阿根塔创新有限公司 可咀嚼配制物
US10525005B2 (en) 2013-05-23 2020-01-07 The General Hospital Corporation Cromolyn compositions and methods thereof
AU2014340182B2 (en) 2013-10-22 2019-05-23 The General Hospital Corporation Cromolyn derivatives and related methods of imaging and treatment
CA2959414C (en) 2014-09-05 2023-03-14 Symbiomix Therapeutics, Llc Secnidazole for use in the treatment of bacterial vaginosis
WO2016196653A1 (en) * 2015-06-01 2016-12-08 Symbiomix Therapeutics, Llc Novel nitroimidazole formulations and uses thereof
CA3033079A1 (en) 2016-08-31 2018-03-08 The General Hospital Corporation Macrophages/microglia in neuro-inflammation associated with neurodegenerative diseases
WO2018154088A1 (en) 2017-02-24 2018-08-30 Merck Patent Gmbh 1, 4, 6-trisubstituted-2-alkyl-1h-benzo[d]imidazole derivatives as dihydroorotate oxygenase inhibitors
CN110662539B (zh) 2017-04-24 2023-08-15 奥里吉恩探索技术有限公司 三取代的苯并三唑衍生物作为二氢乳清酸加氧酶抑制剂的使用方法
KR20210070232A (ko) 2017-07-20 2021-06-14 아즈테라피즈 인코포레이티드 크로몰린 나트륨 및 이부프로펜의 분말화된 제형
EP3508199A1 (de) * 2018-01-05 2019-07-10 Dompé farmaceutici S.p.A. Schnell freisetzende pharmazeutische zusammensetzungen mit ketoprofen-lysinsalz
CA3105392A1 (en) 2018-07-02 2020-01-09 The General Hospital Corporation Powdered formulations of cromolyn sodium and .alpha.-lactose
EP3893945A4 (de) 2018-12-10 2022-11-30 The General Hospital Corporation Cromolynester und verwendungen davon
EP3804531A1 (de) * 2019-10-11 2021-04-14 Begapinol Dr. Schmidt GmbH Granulierung von topinambur
US12458622B2 (en) 2020-04-06 2025-11-04 The General Hospital Corporation Methods of treatment of coronavirus-induced inflammation conditions
US12280037B2 (en) 2020-09-22 2025-04-22 Evofem Biosciences, Inc. Method and pharmaceutical composition for treating or preventing trichomoniasis and uses thereof

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US5084278A (en) * 1989-06-02 1992-01-28 Nortec Development Associates, Inc. Taste-masked pharmaceutical compositions
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US5075114A (en) * 1990-05-23 1991-12-24 Mcneil-Ppc, Inc. Taste masking and sustained release coatings for pharmaceuticals
US5260072A (en) * 1990-08-30 1993-11-09 Mcneil-Ppc, Inc. Rotogranulations and taste masking coatings for preparation of chewable pharmaceutical tablets
CA2068402C (en) * 1991-06-14 1998-09-22 Michael R. Hoy Taste mask coatings for preparation of chewable pharmaceutical tablets
US5225201A (en) * 1991-08-23 1993-07-06 Minnesota Mining And Manufacturing Company Salsalate tablet
ES2150438T3 (es) * 1991-12-30 2000-12-01 Fmc Corp Composicion de esferonizacion a base de celulosa microcristalina.
MX9300110A (es) * 1992-01-13 1994-07-29 Gerhard Gergely Preparacion farmaceutica en la forma de una tableta de efervescencia o de desintegracion o de un granulado de tipo instanteneo y procedimiento para su preparacion.
ZA945944B (en) * 1993-08-13 1996-02-08 Eurand America Inc Procedure for encapsulating nsaids
EP0713389A4 (de) * 1993-08-13 1997-05-21 Bayer Ag Hydrolysierte gelatine als geschmacksverbesserer in einer kautablette
ES2082723B1 (es) * 1994-07-20 1996-10-01 Lilly Sa Formulacion farmaceutica de fluoxetina en forma dispersable.
US5637313A (en) * 1994-12-16 1997-06-10 Watson Laboratories, Inc. Chewable dosage forms
US5529783A (en) * 1994-12-19 1996-06-25 Mcneil-Ppc, Inc. Rotor granulation and coating of acetaminophen, pseudoephedrine, chlorpheniramine, and, optionally dextromethorphan
US5686107A (en) * 1995-01-30 1997-11-11 Fmc Corporation Chewable pharmaceutical tablets
US5639475A (en) * 1995-02-03 1997-06-17 Eurand America, Incorporated Effervescent microcapsules

Also Published As

Publication number Publication date
JP2007137902A (ja) 2007-06-07
KR100563342B1 (ko) 2006-03-22
BR9812590A (pt) 2000-08-01
EP1027038A1 (de) 2000-08-16
IL135121A (en) 2005-07-25
DE69835162T2 (de) 2007-05-31
EP1027038B1 (de) 2006-07-05
CA2303177C (en) 2005-12-06
PL339568A1 (en) 2000-12-18
BR9812590B1 (pt) 2009-01-13
DE69835162D1 (de) 2006-08-17
NO20001670D0 (no) 2000-03-31
AU1063799A (en) 1999-04-27
KR20010024375A (ko) 2001-03-26
CA2303177A1 (en) 1999-04-15
NO20001670L (no) 2000-05-22
EP1027038A4 (de) 2005-02-09
JP2001518491A (ja) 2001-10-16
IL135121A0 (en) 2001-05-20
CN1154481C (zh) 2004-06-23
WO1999017748A1 (en) 1999-04-15
CN1273527A (zh) 2000-11-15
US5904937A (en) 1999-05-18
DK1027038T3 (da) 2006-09-18

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties