ATE332299T1 - Eine sulfonimid-gruppe enthaltende oxazolidinone als antibiotika - Google Patents

Eine sulfonimid-gruppe enthaltende oxazolidinone als antibiotika

Info

Publication number
ATE332299T1
ATE332299T1 AT02720195T AT02720195T ATE332299T1 AT E332299 T1 ATE332299 T1 AT E332299T1 AT 02720195 T AT02720195 T AT 02720195T AT 02720195 T AT02720195 T AT 02720195T AT E332299 T1 ATE332299 T1 AT E332299T1
Authority
AT
Austria
Prior art keywords
antibiotics
membered
linked
formula
sulfonimide group
Prior art date
Application number
AT02720195T
Other languages
English (en)
Inventor
Michael John Betts
Michael Lingard Swain
Neil James Hales
Hoan Khai Huynh
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0108765A external-priority patent/GB0108765D0/en
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE332299T1 publication Critical patent/ATE332299T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT02720195T 2001-04-07 2002-04-03 Eine sulfonimid-gruppe enthaltende oxazolidinone als antibiotika ATE332299T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0108765A GB0108765D0 (en) 2001-04-07 2001-04-07 Method
US33058801P 2001-10-25 2001-10-25

Publications (1)

Publication Number Publication Date
ATE332299T1 true ATE332299T1 (de) 2006-07-15

Family

ID=26245945

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02720195T ATE332299T1 (de) 2001-04-07 2002-04-03 Eine sulfonimid-gruppe enthaltende oxazolidinone als antibiotika

Country Status (7)

Country Link
US (1) US20050032861A1 (de)
EP (1) EP1385844B1 (de)
JP (1) JP2004531518A (de)
AT (1) ATE332299T1 (de)
DE (1) DE60212959T2 (de)
ES (1) ES2268011T3 (de)
WO (1) WO2002081470A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0009803D0 (en) 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
SI1427711T1 (sl) 2001-09-11 2005-12-31 Astrazeneca Ab Oksazolidinonski in/ali izoksazolinski derivati kot antibakterijska sredstva
BR0307103A (pt) * 2002-01-24 2004-12-28 Upjohn Co Dihidrotiazina e dihidrotiopirano oxazolidinovas antimicrobianas
CN1653064A (zh) * 2002-02-28 2005-08-10 阿斯特拉曾尼卡有限公司 噁唑烷酮衍生物、其制备方法以及包含它们的药用组合物
CN1649866A (zh) 2002-02-28 2005-08-03 阿斯特拉曾尼卡有限公司 3－环状基－5－(含氮5－元环)甲基－噁唑烷酮衍生物及其作为抗菌药物的用途
TW200420573A (en) 2002-09-26 2004-10-16 Rib X Pharmaceuticals Inc Bifunctional heterocyclic compounds and methods of making and using same
WO2004048350A2 (en) * 2002-11-28 2004-06-10 Astrazeneca Ab Oxazolidinones as antibacterial agents
GB0306358D0 (en) 2003-03-20 2003-04-23 Astrazeneca Ab Chemical compounds
US8324398B2 (en) 2003-06-03 2012-12-04 Rib-X Pharmaceuticals, Inc. Process for the synthesis of biaryl oxazolidinones
EP1656370B1 (de) 2003-06-03 2012-08-15 Rib-X Pharmaceuticals, Inc. Heterocyclische biarylverbindungen und verfahren zu deren herstellung und anwendung
AR046782A1 (es) 2003-12-17 2005-12-21 Rib X Pharmaceuticals Inc Compuestos heterociclicos de biarilo halogenados, composiciones farmaceuticas que los contienen, metodos para su elaboracion y su uso como medicamentos.
KR100854211B1 (ko) 2003-12-18 2008-08-26 동아제약주식회사 신규한 옥사졸리디논 유도체, 그의 제조방법 및 이를유효성분으로 하는 항생제용 약학 조성물
EP1723159B1 (de) 2004-02-27 2019-06-12 Melinta Therapeutics, Inc. Makrozyklische verbindungen, deren herstellung und verwendung
AU2006231919A1 (en) 2005-04-06 2006-10-12 Pharmacia & Upjohn Company Llc 7-fluoro-1,3-dihydro-indol-2-one oxazolidinones as antibacterial agents
JP5534497B2 (ja) 2005-06-08 2014-07-02 メリンタ セラピューティクス，インコーポレイテッド トリアゾール類の合成方法
DE602006010702D1 (de) 2005-06-29 2010-01-07 Pharmacia & Upjohn Co Llc Homomorpholinoxazolidinone als antibakterielle mittel
RU2659792C1 (ru) 2008-10-10 2018-07-04 Мерк Шарп Энд Домэ Корп. Оксазолидиноны и способ их очистки
CN102224151A (zh) 2008-11-20 2011-10-19 万能药生物有限公司 新的抗微生物剂
MY156354A (en) 2009-02-03 2016-02-15 Merck Sharp & Dohme Crystalline form of r)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyl oxazolidin-2-one dihydrogen phosphate
US8580767B2 (en) 2009-05-28 2013-11-12 Trius Therapeutics, Inc. Oxazolidinone containing dimer compounds, compositions and methods to make and use
KR20120106697A (ko) 2009-06-26 2012-09-26 파나세아 바이오테크 리미티드 신규 아자비시클로헥산
EP2766373B1 (de) * 2011-10-11 2016-08-17 Council of Scientific & Industrial Research Sila-analoga von oxazolidinon-derivaten und ihre herstellung
WO2020147504A1 (en) 2019-01-18 2020-07-23 Merck Sharp & Dohme Corp. Oxazolidinone compounds and methods of use thereof as antibacterial agents

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1222708A (en) * 1968-10-22 1971-02-17 Delalande Sa Novel 5-(n-substituted aminomethyl)-2-oxazolidinones and their process of preparation
MY115155A (en) * 1993-09-09 2003-04-30 Upjohn Co Substituted oxazine and thiazine oxazolidinone antimicrobials.
PT792273E (pt) * 1994-11-15 2003-06-30 Upjohn Co Produtos antibacterianos de oxazolidinona substituida com oxazina e tiazina biciclicas
HUP9901979A3 (en) * 1995-09-01 2000-03-28 Upjohn Co Phenyloxazolidinones having a c-c bond to 4-8 membered heterocyclic rings and pharmaceutical compositions containing the same
DK1114819T3 (da) * 1996-04-11 2008-04-14 Pharmacia & Upjohn Co Llc Fremgangsmåde til fremstilling af oxazolidinoner
DE19707628A1 (de) * 1997-02-26 1998-08-27 Merck Patent Gmbh Oxazolidinone
SK156499A3 (en) * 1997-05-30 2000-06-12 Upjohn Co Oxazolidinone antibacterial agents having a thiocarbonyl functionality
SK7572002A3 (en) * 1999-12-21 2002-12-03 Upjohn Co Oxazolidinones having a sulfoximine functionality and their use as antimicrobial agents

Also Published As

Publication number Publication date
EP1385844B1 (de) 2006-07-05
US20050032861A1 (en) 2005-02-10
EP1385844A1 (de) 2004-02-04
DE60212959D1 (de) 2006-08-17
DE60212959T2 (de) 2007-02-15
WO2002081470A1 (en) 2002-10-17
ES2268011T3 (es) 2007-03-16
JP2004531518A (ja) 2004-10-14

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties