ATE332299T1 - Eine sulfonimid-gruppe enthaltende oxazolidinone als antibiotika - Google Patents

Eine sulfonimid-gruppe enthaltende oxazolidinone als antibiotika

Info

Publication number
ATE332299T1
ATE332299T1 AT02720195T AT02720195T ATE332299T1 AT E332299 T1 ATE332299 T1 AT E332299T1 AT 02720195 T AT02720195 T AT 02720195T AT 02720195 T AT02720195 T AT 02720195T AT E332299 T1 ATE332299 T1 AT E332299T1
Authority
AT
Austria
Prior art keywords
antibiotics
membered
linked
formula
sulfonimide group
Prior art date
Application number
AT02720195T
Other languages
English (en)
Inventor
Michael John Betts
Michael Lingard Swain
Neil James Hales
Hoan Khai Huynh
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0108765A external-priority patent/GB0108765D0/en
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE332299T1 publication Critical patent/ATE332299T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT02720195T 2001-04-07 2002-04-03 Eine sulfonimid-gruppe enthaltende oxazolidinone als antibiotika ATE332299T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0108765A GB0108765D0 (en) 2001-04-07 2001-04-07 Method
US33058801P 2001-10-25 2001-10-25

Publications (1)

Publication Number Publication Date
ATE332299T1 true ATE332299T1 (de) 2006-07-15

Family

ID=26245945

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02720195T ATE332299T1 (de) 2001-04-07 2002-04-03 Eine sulfonimid-gruppe enthaltende oxazolidinone als antibiotika

Country Status (7)

Country Link
US (1) US20050032861A1 (de)
EP (1) EP1385844B1 (de)
JP (1) JP2004531518A (de)
AT (1) ATE332299T1 (de)
DE (1) DE60212959T2 (de)
ES (1) ES2268011T3 (de)
WO (1) WO2002081470A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0009803D0 (en) 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
CA2459766A1 (en) 2001-09-11 2003-03-20 Astrazeneca Ab Oxazolidinone and/or isoxazoline as antibacterial agents
WO2003062231A1 (en) * 2002-01-24 2003-07-31 Pharmacia & Upjohn Company Antimicrobial dihydrothiazine and dihydrothiopyran oxazolidinones
RU2004129278A (ru) * 2002-02-28 2005-06-10 Астразенека Аб (Se) Химические соединения
US7473699B2 (en) * 2002-02-28 2009-01-06 Astrazeneca Ab 3-cyclyl-5-(nitrogen-containing 5-membered ring)methyl-oxazolidinone derivatives and their use as antibacterial agents
TW200420573A (en) 2002-09-26 2004-10-16 Rib X Pharmaceuticals Inc Bifunctional heterocyclic compounds and methods of making and using same
EP1581524A2 (de) * 2002-11-28 2005-10-05 AstraZeneca AB Oxazolidinone mit antibakterieller wirksamkeit
GB0306358D0 (en) 2003-03-20 2003-04-23 Astrazeneca Ab Chemical compounds
US8324398B2 (en) 2003-06-03 2012-12-04 Rib-X Pharmaceuticals, Inc. Process for the synthesis of biaryl oxazolidinones
PT1656370E (pt) 2003-06-03 2012-11-29 Rib X Pharmaceuticals Inc Compostos biaril-heterocíclicos e métodos de os produzir e de os utilizar
TW200526649A (en) 2003-12-17 2005-08-16 Rib X Pharmaceuticals Inc Halogenated biaryl heterocyclic compounds and methods of making and using the same
KR100854211B1 (ko) 2003-12-18 2008-08-26 동아제약주식회사 신규한 옥사졸리디논 유도체, 그의 제조방법 및 이를유효성분으로 하는 항생제용 약학 조성물
US8202843B2 (en) 2004-02-27 2012-06-19 Rib-X Pharmaceuticals, Inc. Macrocyclic compounds and methods of making and using the same
AU2006231919A1 (en) 2005-04-06 2006-10-12 Pharmacia & Upjohn Company Llc 7-fluoro-1,3-dihydro-indol-2-one oxazolidinones as antibacterial agents
DE602006019870D1 (de) 2005-06-08 2011-03-10 Rib X Pharmaceuticals Inc Verfahren zur synthese von triazolen
CA2610978A1 (en) 2005-06-29 2007-01-04 Pharmacia & Upjohn Company Llc Homomorpholine oxazolidinones as antibacterial agents
MX2011003820A (es) 2008-10-10 2011-06-16 Trius Therapeutics Metodos para preparar oxazolidinonas y composiciones que las contienen.
KR20110092309A (ko) 2008-11-20 2011-08-17 파나세아 바이오테크 리미티드 신규 항균제
SG173497A1 (en) 2009-02-03 2011-09-29 Trius Therapeutics Crystalline form of r)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyl oxazolidin-2-one dihydrogen phosphate
US8580767B2 (en) 2009-05-28 2013-11-12 Trius Therapeutics, Inc. Oxazolidinone containing dimer compounds, compositions and methods to make and use
CA2765692A1 (en) 2009-06-26 2010-12-29 Panacea Biotec Ltd. Novel azabicyclohexanes
JP6162704B2 (ja) * 2011-10-11 2017-07-12 カウンシル オブ サイエンティフィク アンド インダストリアル リサーチ オキサゾリジノン誘導体のシラアナログ及びその合成
EP3914587A4 (de) * 2019-01-18 2022-11-23 Merck Sharp & Dohme LLC Oxazolidinonverbindungen und verwendungen davon als antibakterielle mittel

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1222708A (en) * 1968-10-22 1971-02-17 Delalande Sa Novel 5-(n-substituted aminomethyl)-2-oxazolidinones and their process of preparation
MY115155A (en) * 1993-09-09 2003-04-30 Upjohn Co Substituted oxazine and thiazine oxazolidinone antimicrobials.
NZ295528A (en) * 1994-11-15 1999-03-29 Upjohn Co Bicyclic oxazine and thiazine oxazolidinone antibacterials
CN1072222C (zh) * 1995-09-01 2001-10-03 法玛西雅厄普约翰公司 以c－c键连接于4－8元杂环环的苯基噁唑烷酮
ATE209193T1 (de) * 1996-04-11 2001-12-15 Upjohn Co Verfahren zur herstellung von oxazolidinonen
DE19707628A1 (de) * 1997-02-26 1998-08-27 Merck Patent Gmbh Oxazolidinone
CA2288750A1 (en) * 1997-05-30 1998-12-03 Pharmacia & Upjohn Company Oxazolidinone antibacterial agents having a thiocarbonyl functionality
HUP0203869A2 (hu) * 1999-12-21 2003-07-28 Pharmacia & Upjohn Co. Szulfoximin funkcionalitással rendelkező oxazolidinok és alkalmazásuk mikrobaellenes szerként, a vegyületeket tartalmazó gyógyszerkészítmények

Also Published As

Publication number Publication date
EP1385844A1 (de) 2004-02-04
US20050032861A1 (en) 2005-02-10
JP2004531518A (ja) 2004-10-14
DE60212959D1 (de) 2006-08-17
EP1385844B1 (de) 2006-07-05
ES2268011T3 (es) 2007-03-16
DE60212959T2 (de) 2007-02-15
WO2002081470A1 (en) 2002-10-17

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties