ATE332299T1 - Eine sulfonimid-gruppe enthaltende oxazolidinone als antibiotika - Google Patents

Eine sulfonimid-gruppe enthaltende oxazolidinone als antibiotika

Info

Publication number
ATE332299T1
ATE332299T1 AT02720195T AT02720195T ATE332299T1 AT E332299 T1 ATE332299 T1 AT E332299T1 AT 02720195 T AT02720195 T AT 02720195T AT 02720195 T AT02720195 T AT 02720195T AT E332299 T1 ATE332299 T1 AT E332299T1
Authority
AT
Austria
Prior art keywords
antibiotics
membered
linked
formula
sulfonimide group
Prior art date
Application number
AT02720195T
Other languages
English (en)
Inventor
Michael John Betts
Michael Lingard Swain
Neil James Hales
Hoan Khai Huynh
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0108765A external-priority patent/GB0108765D0/en
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE332299T1 publication Critical patent/ATE332299T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT02720195T 2001-04-07 2002-04-03 Eine sulfonimid-gruppe enthaltende oxazolidinone als antibiotika ATE332299T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0108765A GB0108765D0 (en) 2001-04-07 2001-04-07 Method
US33058801P 2001-10-25 2001-10-25

Publications (1)

Publication Number Publication Date
ATE332299T1 true ATE332299T1 (de) 2006-07-15

Family

ID=26245945

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02720195T ATE332299T1 (de) 2001-04-07 2002-04-03 Eine sulfonimid-gruppe enthaltende oxazolidinone als antibiotika

Country Status (7)

Country Link
US (1) US20050032861A1 (de)
EP (1) EP1385844B1 (de)
JP (1) JP2004531518A (de)
AT (1) ATE332299T1 (de)
DE (1) DE60212959T2 (de)
ES (1) ES2268011T3 (de)
WO (1) WO2002081470A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0009803D0 (en) 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
AU2002329393B2 (en) 2001-09-11 2008-06-12 Astrazeneca Ab Oxazolidinone and/or isoxazoline as antibacterial agents
WO2003062231A1 (en) 2002-01-24 2003-07-31 Pharmacia & Upjohn Company Antimicrobial dihydrothiazine and dihydrothiopyran oxazolidinones
WO2003072576A2 (en) * 2002-02-28 2003-09-04 Astrazeneca Ab Oxazolidinone derivatives, processes for their preparation, and pharmaceutical compositions containing them
NZ535592A (en) 2002-02-28 2006-07-28 Astrazeneca Ab 3-cyclyl-5-(nitrogen-containing 5-membered ring) methyl-oxazolidinone derivatives and their use as antibacterial agents
US7091196B2 (en) 2002-09-26 2006-08-15 Rib-X Pharmaceuticals, Inc. Bifunctional heterocyclic compounds and methods of making and using same
CA2507628A1 (en) * 2002-11-28 2004-06-10 Astrazeneca Ab Oxazolidinones as antibacterial agents
GB0306358D0 (en) 2003-03-20 2003-04-23 Astrazeneca Ab Chemical compounds
US8324398B2 (en) 2003-06-03 2012-12-04 Rib-X Pharmaceuticals, Inc. Process for the synthesis of biaryl oxazolidinones
TWI378092B (en) 2003-06-03 2012-12-01 Rib X Pharmaceuticals Inc Biaryl heterocyclic compounds and methods of making and using the same
JP2007514782A (ja) 2003-12-17 2007-06-07 リブ−エックス ファーマシューティカルズ，インコーポレイテッド ハロゲン化ビアリール複素環式化合物ならびにその作製方法および使用方法
KR100854211B1 (ko) 2003-12-18 2008-08-26 동아제약주식회사 신규한 옥사졸리디논 유도체, 그의 제조방법 및 이를유효성분으로 하는 항생제용 약학 조성물
EP2716647A3 (de) 2004-02-27 2014-08-20 Rib-X Pharmaceuticals, Inc. Makrocyclische Verbindungen Und Verfahren Zu Deren Herstellung Und Anwendung
AU2006231919A1 (en) 2005-04-06 2006-10-12 Pharmacia & Upjohn Company Llc 7-fluoro-1,3-dihydro-indol-2-one oxazolidinones as antibacterial agents
EP1904489B1 (de) 2005-06-08 2011-01-26 Rib-X Pharmaceuticals, Inc. Verfahren zur synthese von triazolen
CA2610978A1 (en) 2005-06-29 2007-01-04 Pharmacia & Upjohn Company Llc Homomorpholine oxazolidinones as antibacterial agents
RU2659792C1 (ru) 2008-10-10 2018-07-04 Мерк Шарп Энд Домэ Корп. Оксазолидиноны и способ их очистки
CN102224151A (zh) 2008-11-20 2011-10-19 万能药生物有限公司 新的抗微生物剂
MX384300B (es) 2009-02-03 2025-03-14 Merck Sharp & Dohme Llc Forma cristalina del fosfato de dihidrogeno r) -3- (4- (2- (2-metiltetrazol-5-il) piridin-5-il) -3-fluorofenil) -5-hidroximetil oxazolidin-2-ona.
US8580767B2 (en) 2009-05-28 2013-11-12 Trius Therapeutics, Inc. Oxazolidinone containing dimer compounds, compositions and methods to make and use
RU2012102094A (ru) 2009-06-26 2013-08-10 Панацеа Биотек Лтд. Новые азабициклогексаны
EP2766373B1 (de) * 2011-10-11 2016-08-17 Council of Scientific & Industrial Research Sila-analoga von oxazolidinon-derivaten und ihre herstellung
EP3914587A4 (de) * 2019-01-18 2022-11-23 Merck Sharp & Dohme LLC Oxazolidinonverbindungen und verwendungen davon als antibakterielle mittel

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1222708A (en) * 1968-10-22 1971-02-17 Delalande Sa Novel 5-(n-substituted aminomethyl)-2-oxazolidinones and their process of preparation
MY115155A (en) * 1993-09-09 2003-04-30 Upjohn Co Substituted oxazine and thiazine oxazolidinone antimicrobials.
BR9509673A (pt) * 1994-11-15 1997-09-30 Upjohn Co Compostos e uso dos mesmos
DE69616366T2 (de) * 1995-09-01 2002-07-04 Upjohn Co Phenyloxazolidinone mit einer c-c-bindung zu 4-8 gliedrigen heterocyclen
SG85683A1 (en) * 1996-04-11 2002-01-15 Upjohn Co Process to prepare oxazolidinones
DE19707628A1 (de) * 1997-02-26 1998-08-27 Merck Patent Gmbh Oxazolidinone
FI19992555A7 (fi) * 1997-05-30 1999-11-30 Upjohn Co Antibakteerisia oksatosolidinoniaineita, joilla on tiokarbonyylifunktionaalisuus
SK7572002A3 (en) * 1999-12-21 2002-12-03 Upjohn Co Oxazolidinones having a sulfoximine functionality and their use as antimicrobial agents

Also Published As

Publication number Publication date
EP1385844B1 (de) 2006-07-05
DE60212959T2 (de) 2007-02-15
DE60212959D1 (de) 2006-08-17
ES2268011T3 (es) 2007-03-16
WO2002081470A1 (en) 2002-10-17
EP1385844A1 (de) 2004-02-04
US20050032861A1 (en) 2005-02-10
JP2004531518A (ja) 2004-10-14

Similar Documents

Publication Publication Date Title
DE60212959D1 (de) Eine sulfonimid-gruppe enthaltende oxazolidinone als antibiotika
ATE293110T1 (de) Substituierte isoxazoline und ihre verwendung als antibakterielle wirkstoffe
ATE323087T1 (de) Aryl substituierte oxazolidinone mit antibacterieller activität
WO1999064417A3 (en) Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them
ATE258552T1 (de) Oxazolidinon-derivate als antibiotika, verfahren zu ihrer herstellung und diese derivate enthaltende pharmazeutische zusammensetzungen
IS6583A (is) Oxasólidínónafleiður með sýklalyfsvirkni
BR9914379A (pt) Composto, processo para a preparação de um composto, método para a produção de um efeito antibacteriano em um animal de sangue quente, uso de um composto, e, composição farmacêutica
NO986055D0 (no) Nye heterocykliske forbindelser, deres fremstilling, farmas÷ytiske preparat
NO20053133L (no) Kjemiske forbindelser.
ATE386031T1 (de) Benzoylaminopyridylcarbonsäurederivate als glucokinaseaktivatoren
DK0607193T3 (da) Antifugale triazolderivater
FI822543A0 (fi) Pyrrolidinderivat
WO2002080841A3 (en) Antibacterial oxazolidinones with a cyclic sulphilimine or sulphoximine
NZ516100A (en) Streptogramin derivatives, preparation and compositions containing them
ES8800175A1 (es) Procedimiento para la obtencion de derivados de acido 5-(azoli-loxifenilcarbamoil)-barbiturico.
WO2003072576A3 (en) Oxazolidinone derivatives, processes for their preparation, and pharmaceutical compositions containing them
ATE269862T1 (de) Substituierte thiazolidinedione und oxazolidinedione mit antidiabetischen, hypolipidämischen und antihypertensiven eigenschaften
EP0878475A3 (de) 5-(4-Piperidinyl)dibenzothiazepine derivate und 5-(4-piperidinyl)dibenzoxazepinderivate, und antiarrhythmische Mittel

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties