ATE323087T1 - Aryl substituierte oxazolidinone mit antibacterieller activität - Google Patents

Aryl substituierte oxazolidinone mit antibacterieller activität

Info

Publication number
ATE323087T1
ATE323087T1 AT02770098T AT02770098T ATE323087T1 AT E323087 T1 ATE323087 T1 AT E323087T1 AT 02770098 T AT02770098 T AT 02770098T AT 02770098 T AT02770098 T AT 02770098T AT E323087 T1 ATE323087 T1 AT E323087T1
Authority
AT
Austria
Prior art keywords
antibacterial activity
aryl substituted
substituted oxazolidinones
het
membered
Prior art date
Application number
AT02770098T
Other languages
English (en)
Inventor
Michael Barry Gravestock
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Application granted granted Critical
Publication of ATE323087T1 publication Critical patent/ATE323087T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AT02770098T 2001-10-25 2002-10-23 Aryl substituierte oxazolidinone mit antibacterieller activität ATE323087T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33058901P 2001-10-25 2001-10-25

Publications (1)

Publication Number Publication Date
ATE323087T1 true ATE323087T1 (de) 2006-04-15

Family

ID=23290426

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02770098T ATE323087T1 (de) 2001-10-25 2002-10-23 Aryl substituierte oxazolidinone mit antibacterieller activität

Country Status (7)

Country Link
US (1) US20050043374A1 (de)
EP (1) EP1446403B1 (de)
JP (1) JP2005519870A (de)
AT (1) ATE323087T1 (de)
DE (1) DE60210654T2 (de)
GB (1) GB2396350A (de)
WO (1) WO2003035648A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002329393B2 (en) 2001-09-11 2008-06-12 Astrazeneca Ab Oxazolidinone and/or isoxazoline as antibacterial agents
JP2005512975A (ja) 2001-10-25 2005-05-12 アストラゼネカ アクチボラグ 抗菌薬として有用なイソキサゾリン誘導体
NZ535592A (en) 2002-02-28 2006-07-28 Astrazeneca Ab 3-cyclyl-5-(nitrogen-containing 5-membered ring) methyl-oxazolidinone derivatives and their use as antibacterial agents
WO2003072576A2 (en) 2002-02-28 2003-09-04 Astrazeneca Ab Oxazolidinone derivatives, processes for their preparation, and pharmaceutical compositions containing them
US7091196B2 (en) 2002-09-26 2006-08-15 Rib-X Pharmaceuticals, Inc. Bifunctional heterocyclic compounds and methods of making and using same
CA2507628A1 (en) 2002-11-28 2004-06-10 Astrazeneca Ab Oxazolidinones as antibacterial agents
GB0306357D0 (en) 2003-03-20 2003-04-23 Astrazeneca Ab Chemical compounds
GB0306358D0 (en) 2003-03-20 2003-04-23 Astrazeneca Ab Chemical compounds
US8324398B2 (en) 2003-06-03 2012-12-04 Rib-X Pharmaceuticals, Inc. Process for the synthesis of biaryl oxazolidinones
TWI378092B (en) 2003-06-03 2012-12-01 Rib X Pharmaceuticals Inc Biaryl heterocyclic compounds and methods of making and using the same
JP2007514782A (ja) 2003-12-17 2007-06-07 リブ−エックス ファーマシューティカルズ，インコーポレイテッド ハロゲン化ビアリール複素環式化合物ならびにその作製方法および使用方法
KR100854211B1 (ko) 2003-12-18 2008-08-26 동아제약주식회사 신규한 옥사졸리디논 유도체, 그의 제조방법 및 이를유효성분으로 하는 항생제용 약학 조성물
EP2716647A3 (de) 2004-02-27 2014-08-20 Rib-X Pharmaceuticals, Inc. Makrocyclische Verbindungen Und Verfahren Zu Deren Herstellung Und Anwendung
GB0411596D0 (en) * 2004-05-25 2004-06-30 Astrazeneca Ab Chemical process
EP1904489B1 (de) 2005-06-08 2011-01-26 Rib-X Pharmaceuticals, Inc. Verfahren zur synthese von triazolen
RU2659792C1 (ru) 2008-10-10 2018-07-04 Мерк Шарп Энд Домэ Корп. Оксазолидиноны и способ их очистки
MX384300B (es) 2009-02-03 2025-03-14 Merck Sharp & Dohme Llc Forma cristalina del fosfato de dihidrogeno r) -3- (4- (2- (2-metiltetrazol-5-il) piridin-5-il) -3-fluorofenil) -5-hidroximetil oxazolidin-2-ona.
US8580767B2 (en) 2009-05-28 2013-11-12 Trius Therapeutics, Inc. Oxazolidinone containing dimer compounds, compositions and methods to make and use
KR101128029B1 (ko) 2010-03-08 2012-03-29 주식회사 레고켐 바이오사이언스 (ｒ)-3-(3-플루오로-4-(1-메틸-5,6-다이하이드로-1,2,4-트리아진-4(1ｈ)-일)페닐)-5-(치환된 메틸)옥사졸리딘-2-온 유도체의 제조방법
CN102190656B (zh) * 2010-03-16 2014-03-26 山东轩竹医药科技有限公司 含有五元杂环的噁唑烷酮抗菌素
US9862710B2 (en) 2013-03-15 2018-01-09 Istituto Euro Mediterraneo Di Scienza E Tecnologia 1,2,4-oxadiazol compounds active against gram-positive pathogens
CA2907032C (en) * 2013-03-15 2021-04-20 I.E.Me.St - Istituto Euro Mediterraneo Di Scienza E Tecnologia 1, 2, 4-oxadiazol compounds active against gram-positive pathogens
ITRM20130155A1 (it) * 2013-03-15 2014-09-16 I E Me S T Istituto Euro Mediter Raneo Di Scien Nuovi composti 1,2,4-ossadiazolici attivi contro patogeni gram-positivi.
KR101561964B1 (ko) 2013-11-15 2015-10-20 한국과학기술연구원 옥사졸리디논 화합물 및 이를 포함하는 c형 간염 예방 또는 치료용 약학 조성물

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3318878A (en) * 1966-04-14 1967-05-09 Smith Kline French Lab Nitrothiophene compounds
NL137326C (de) * 1967-08-26
GB1222708A (en) * 1968-10-22 1971-02-17 Delalande Sa Novel 5-(n-substituted aminomethyl)-2-oxazolidinones and their process of preparation
SK283420B6 (sk) * 1992-05-08 2003-07-01 Pharmacia & Upjohn Company Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny
GB9812019D0 (en) * 1998-06-05 1998-07-29 Zeneca Ltd Chemical compounds

Also Published As

Publication number Publication date
JP2005519870A (ja) 2005-07-07
DE60210654D1 (de) 2006-05-24
EP1446403A1 (de) 2004-08-18
EP1446403B1 (de) 2006-04-12
GB2396350A (en) 2004-06-23
US20050043374A1 (en) 2005-02-24
WO2003035648A1 (en) 2003-05-01
DE60210654T2 (de) 2007-01-25
GB0408399D0 (en) 2004-05-19

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Legal Events

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