ATE323087T1 - Aryl substituierte oxazolidinone mit antibacterieller activität - Google Patents

Aryl substituierte oxazolidinone mit antibacterieller activität

Info

Publication number
ATE323087T1
ATE323087T1 AT02770098T AT02770098T ATE323087T1 AT E323087 T1 ATE323087 T1 AT E323087T1 AT 02770098 T AT02770098 T AT 02770098T AT 02770098 T AT02770098 T AT 02770098T AT E323087 T1 ATE323087 T1 AT E323087T1
Authority
AT
Austria
Prior art keywords
antibacterial activity
aryl substituted
substituted oxazolidinones
het
membered
Prior art date
Application number
AT02770098T
Other languages
English (en)
Inventor
Michael Barry Gravestock
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Application granted granted Critical
Publication of ATE323087T1 publication Critical patent/ATE323087T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT02770098T 2001-10-25 2002-10-23 Aryl substituierte oxazolidinone mit antibacterieller activität ATE323087T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33058901P 2001-10-25 2001-10-25

Publications (1)

Publication Number Publication Date
ATE323087T1 true ATE323087T1 (de) 2006-04-15

Family

ID=23290426

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02770098T ATE323087T1 (de) 2001-10-25 2002-10-23 Aryl substituierte oxazolidinone mit antibacterieller activität

Country Status (7)

Country Link
US (1) US20050043374A1 (de)
EP (1) EP1446403B1 (de)
JP (1) JP2005519870A (de)
AT (1) ATE323087T1 (de)
DE (1) DE60210654T2 (de)
GB (1) GB2396350A (de)
WO (1) WO2003035648A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1427711T1 (sl) 2001-09-11 2005-12-31 Astrazeneca Ab Oksazolidinonski in/ali izoksazolinski derivati kot antibakterijska sredstva
EP1443930A1 (de) 2001-10-25 2004-08-11 AstraZeneca AB Isoxazolinderivative verwendbar als antimikrobielle agenzien
CN1649866A (zh) 2002-02-28 2005-08-03 阿斯特拉曾尼卡有限公司 3－环状基－5－(含氮5－元环)甲基－噁唑烷酮衍生物及其作为抗菌药物的用途
CN1653064A (zh) 2002-02-28 2005-08-10 阿斯特拉曾尼卡有限公司 噁唑烷酮衍生物、其制备方法以及包含它们的药用组合物
TW200420573A (en) 2002-09-26 2004-10-16 Rib X Pharmaceuticals Inc Bifunctional heterocyclic compounds and methods of making and using same
WO2004048350A2 (en) * 2002-11-28 2004-06-10 Astrazeneca Ab Oxazolidinones as antibacterial agents
GB0306357D0 (en) * 2003-03-20 2003-04-23 Astrazeneca Ab Chemical compounds
GB0306358D0 (en) 2003-03-20 2003-04-23 Astrazeneca Ab Chemical compounds
EP1656370B1 (de) 2003-06-03 2012-08-15 Rib-X Pharmaceuticals, Inc. Heterocyclische biarylverbindungen und verfahren zu deren herstellung und anwendung
US8324398B2 (en) 2003-06-03 2012-12-04 Rib-X Pharmaceuticals, Inc. Process for the synthesis of biaryl oxazolidinones
AR046782A1 (es) 2003-12-17 2005-12-21 Rib X Pharmaceuticals Inc Compuestos heterociclicos de biarilo halogenados, composiciones farmaceuticas que los contienen, metodos para su elaboracion y su uso como medicamentos.
KR100854211B1 (ko) 2003-12-18 2008-08-26 동아제약주식회사 신규한 옥사졸리디논 유도체, 그의 제조방법 및 이를유효성분으로 하는 항생제용 약학 조성물
EP1723159B1 (de) 2004-02-27 2019-06-12 Melinta Therapeutics, Inc. Makrozyklische verbindungen, deren herstellung und verwendung
GB0411596D0 (en) * 2004-05-25 2004-06-30 Astrazeneca Ab Chemical process
JP5534497B2 (ja) 2005-06-08 2014-07-02 メリンタ セラピューティクス，インコーポレイテッド トリアゾール類の合成方法
RU2659792C1 (ru) 2008-10-10 2018-07-04 Мерк Шарп Энд Домэ Корп. Оксазолидиноны и способ их очистки
MY156354A (en) 2009-02-03 2016-02-15 Merck Sharp & Dohme Crystalline form of r)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyl oxazolidin-2-one dihydrogen phosphate
US8580767B2 (en) 2009-05-28 2013-11-12 Trius Therapeutics, Inc. Oxazolidinone containing dimer compounds, compositions and methods to make and use
KR101128029B1 (ko) * 2010-03-08 2012-03-29 주식회사 레고켐 바이오사이언스 (ｒ)-3-(3-플루오로-4-(1-메틸-5,6-다이하이드로-1,2,4-트리아진-4(1ｈ)-일)페닐)-5-(치환된 메틸)옥사졸리딘-2-온 유도체의 제조방법
CN102190656B (zh) * 2010-03-16 2014-03-26 山东轩竹医药科技有限公司 含有五元杂环的噁唑烷酮抗菌素
JP6402120B2 (ja) * 2013-03-15 2018-10-10 ウニヴェルシタ デッリ ストゥーディ ディ ミラノ − ビコッカ グラム陽性病原菌に対する活性のある新規の１，２，４−オキサジアゾール化合物
US9862710B2 (en) 2013-03-15 2018-01-09 Istituto Euro Mediterraneo Di Scienza E Tecnologia 1,2,4-oxadiazol compounds active against gram-positive pathogens
ITRM20130155A1 (it) * 2013-03-15 2014-09-16 I E Me S T Istituto Euro Mediter Raneo Di Scien Nuovi composti 1,2,4-ossadiazolici attivi contro patogeni gram-positivi.
KR101561964B1 (ko) 2013-11-15 2015-10-20 한국과학기술연구원 옥사졸리디논 화합물 및 이를 포함하는 c형 간염 예방 또는 치료용 약학 조성물

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3318878A (en) * 1966-04-14 1967-05-09 Smith Kline French Lab Nitrothiophene compounds
NL137326C (de) * 1967-08-26
GB1222708A (en) * 1968-10-22 1971-02-17 Delalande Sa Novel 5-(n-substituted aminomethyl)-2-oxazolidinones and their process of preparation
SK283420B6 (sk) * 1992-05-08 2003-07-01 Pharmacia & Upjohn Company Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny
GB9812019D0 (en) * 1998-06-05 1998-07-29 Zeneca Ltd Chemical compounds

Also Published As

Publication number Publication date
DE60210654D1 (de) 2006-05-24
GB2396350A (en) 2004-06-23
EP1446403B1 (de) 2006-04-12
JP2005519870A (ja) 2005-07-07
EP1446403A1 (de) 2004-08-18
WO2003035648A1 (en) 2003-05-01
DE60210654T2 (de) 2007-01-25
US20050043374A1 (en) 2005-02-24
GB0408399D0 (en) 2004-05-19

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