ATE332979T1 - Detektion von änderungen von tumor-suppressor genen zur diagnose von krebs - Google Patents

Detektion von änderungen von tumor-suppressor genen zur diagnose von krebs

Info

Publication number
ATE332979T1
ATE332979T1 AT95916999T AT95916999T ATE332979T1 AT E332979 T1 ATE332979 T1 AT E332979T1 AT 95916999 T AT95916999 T AT 95916999T AT 95916999 T AT95916999 T AT 95916999T AT E332979 T1 ATE332979 T1 AT E332979T1
Authority
AT
Austria
Prior art keywords
detection
changes
cdk4i
gene
tumor suppressor
Prior art date
Application number
AT95916999T
Other languages
English (en)
Inventor
Dennis A Carson
Tsutomu Nobori
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22854518&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE332979(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ California filed Critical Univ California
Application granted granted Critical
Publication of ATE332979T1 publication Critical patent/ATE332979T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT95916999T 1994-04-14 1995-04-12 Detektion von änderungen von tumor-suppressor genen zur diagnose von krebs ATE332979T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/227,800 US6689561B1 (en) 1994-04-14 1994-04-14 Tumor suppressor gene and methods for detection of cancer, monitoring of tumor progression and cancer treatment

Publications (1)

Publication Number Publication Date
ATE332979T1 true ATE332979T1 (de) 2006-08-15

Family

ID=22854518

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95916999T ATE332979T1 (de) 1994-04-14 1995-04-12 Detektion von änderungen von tumor-suppressor genen zur diagnose von krebs

Country Status (7)

Country Link
US (1) US6689561B1 (de)
EP (1) EP0756488B1 (de)
JP (2) JPH09511910A (de)
AT (1) ATE332979T1 (de)
AU (1) AU2385095A (de)
DE (1) DE69535107D1 (de)
WO (1) WO1995028169A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1128049A (zh) * 1994-03-18 1996-07-31 犹他大学研究基金会 多肿瘤抑制因子基因种系突变及检测该基因癌肿倾向性的方法
US6060301A (en) * 1994-03-18 2000-05-09 Myriad Genetics, Inc. Vector containing MTS1E1β gene
CN1128935A (zh) * 1994-03-18 1996-08-14 亿万遗传股份有限公司 多肿瘤抑制因子基因、其突变和用该基因序列诊断癌肿的方法
DE19539130C2 (de) * 1995-02-28 1999-05-12 Max Planck Gesellschaft Mittel zur Therapie von Tumoren und anderen Hyperplasien
CZ15498A3 (cs) 1995-07-17 1998-07-15 Board Of Regents, The University Of Texas System Konstrukce pro expresi pl6 a její aplikace při léčení rakoviny
US7163925B1 (en) 1995-07-17 2007-01-16 Board Of Regents, The University Of Texas System p16 expression constructs and their application in cancer therapy
EP2327797B1 (de) 1997-04-01 2015-11-25 Illumina Cambridge Limited Verfahren zur Vervielfältigung von Nukleinsäuren
US6573044B1 (en) 1997-08-07 2003-06-03 The Regents Of The University Of California Methods of using chemical libraries to search for new kinase inhibitors
AU1627499A (en) * 1997-12-05 1999-06-28 Chiron Corporation Human "kismet" protein (hkis) acts as a tumor suppressor
EP1042509A1 (de) * 1997-12-24 2000-10-11 The Regents of the University of California Verfahren durch gebrauch an oligonukleotidarrays zum suchen von neuen kinase-inhibitoren
US6289229B1 (en) 1998-01-20 2001-09-11 Scimed Life Systems, Inc. Readable probe array for in vivo use
US6797471B2 (en) * 2000-08-04 2004-09-28 Board Of Regents, The University Of Texas System Detection and diagnosis of smoking related cancers
GB0413346D0 (en) 2004-06-15 2004-07-21 Theryte Ltd Treating cancer
US20060188507A1 (en) * 2005-02-11 2006-08-24 Elias Georges Methods for identifying chemotherapeutic resistance in non-hematopoietic tumors
EP1989329A2 (de) * 2006-01-25 2008-11-12 Board of Regents, The University of Texas System Erkennung und diagnose von durch rauchen bedingten krebserkrankungen
US20100086918A1 (en) * 2006-07-31 2010-04-08 The Regents Of The University Of California Methods for High Sensitivity Detection of Genetic Polymorphisms
WO2009077642A1 (en) * 2007-12-19 2009-06-25 University Of Helsinki Screening method
US8642007B2 (en) 2010-09-20 2014-02-04 Yanping Kong Method and compound for treatment of cancer using phosphorous-32 labeled DNA

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4681840A (en) * 1984-01-18 1987-07-21 The United States Of America As Represented By The Secretary Of Commerce Deoxyribonucleic acid molecules useful as probes for detecting oncogenes incorporated into chromosomal DNA
US6211334B1 (en) * 1992-10-16 2001-04-03 Cold Spring Harbor Cell-cycle regulatory proteins, and uses related thereto
CA2146965C (en) * 1992-10-16 2003-07-29 David H. Beach Cyclin complex rearrangement and uses related thereto
CN1128935A (zh) * 1994-03-18 1996-08-14 亿万遗传股份有限公司 多肿瘤抑制因子基因、其突变和用该基因序列诊断癌肿的方法
US5691147A (en) * 1994-06-02 1997-11-25 Mitotix, Inc. CDK4 binding assay
CZ15498A3 (cs) * 1995-07-17 1998-07-15 Board Of Regents, The University Of Texas System Konstrukce pro expresi pl6 a její aplikace při léčení rakoviny

Also Published As

Publication number Publication date
EP0756488A1 (de) 1997-02-05
US6689561B1 (en) 2004-02-10
AU2385095A (en) 1995-11-10
JP2005245469A (ja) 2005-09-15
JPH09511910A (ja) 1997-12-02
DE69535107D1 (de) 2006-08-24
WO1995028169A1 (en) 1995-10-26
EP0756488B1 (de) 2006-07-12
EP0756488A4 (de) 1997-07-02

Similar Documents

Publication Publication Date Title
ATE332979T1 (de) Detektion von änderungen von tumor-suppressor genen zur diagnose von krebs
ATE454468T1 (de) Nachweis der instabilität von mikrosatelliten und verwendung davon bei der tumordiagnose
GB2250993B (en) Stromelysin-3 and its application in the diagnosis and treatment of malignant breast cancer
WO1997036535A3 (en) Biomarkers for detection, diagnosis and prognosis of prostate cancer
WO2000055180A3 (en) Human lung cancer associated gene sequences and polypeptides
WO2002044331A3 (en) Dap-kinase and hoxa9, two human genes associated with genesis, progression, and aggressiveness of non-small cell lung cancer
ATE364089T1 (de) Reagenzien und methoden zum nachweis von erkrankungen der brust
ATE345399T1 (de) Biomarker und targets für die diagnose, prognose und behandlung von prostat krankheiten
ATE198513T1 (de) Ptpalpha-bestimmung in der tumordiagnose und - prognose
NO970624L (no) In vivo mutasjoner og polymorfismer i det 17q-koblete bryst-og ovariekreft mottagelighetsgener
DE69507470D1 (de) Diagnose von krebs, dessen zellen das am tyrosin phosphorylierte crkl-protein exprimieren
ATE488529T1 (de) Zusammensetzungen und verfahren zur behandlung von tumoren
EP2366712A3 (de) TS10Q23.3 Tumorunterdrückung
WO2001018046A3 (en) Ovarian tumor sequences and methods of use therefor
ATE466938T1 (de) Prostata-spezifisches gen pcgem1 und methoden zu dessen verwendung zur erkennung, behandlung und prävention von prostatakrebs
Emterling et al. Clinicopathological significance of microsatellite instability and mutated RIZ in colorectal cancer
DE60016405D1 (de) Neurodegenerative-erkrankung verwandtes gen
EP1012338A4 (de) Ein tumorsuppressor namens ts10q23.3
UA93344C2 (ru) ПОЛИМОРФИЗМ ЧЕЛОВЕЧЕСКОГО ГЕНА NBS1 657del5, КОТОРЫЙ ИСПОЛЬЗУЕТСЯ ДЛЯ ДИАГНОСТИКИ УНАСЛЕДОВАННОЙ СКЛОННОСТИ K РАКУ ПРОСТАТЫ ИЛИ ИНВАЗИВНОГО РАКУ МОЛОЧНОЙ ЖЕЛЕЗЫ ДОЛЬКОВОГО ПОДТИПА
DE69939623D1 (de) Polymorphe marker von prostatakarzinom tumorantigen-1 (pcta-1)
DE69739653D1 (de) Reagentia und verfahren zum nachweis von brustkrankheiten
WO2001055450A3 (en) AMPLIFIED GENES AT 17q23
EP1446485A4 (de) Diagnoseverfahren für krebs, das durch den nachweis der deletion des g-csf-exons 3 gekennzeichnet ist
WO2002081656A3 (en) Enhanced diagnostic potential of prostate-specific antigen expressing cells
EP1438326A4 (de) Diagnose, behandlung und prävention von krebs mit cables

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties