ATE333281T1 - Agonisten und antagonisten von benzodiazepinrezeptoren des peripheren typs - Google Patents

Agonisten und antagonisten von benzodiazepinrezeptoren des peripheren typs

Info

Publication number
ATE333281T1
ATE333281T1 AT99966269T AT99966269T ATE333281T1 AT E333281 T1 ATE333281 T1 AT E333281T1 AT 99966269 T AT99966269 T AT 99966269T AT 99966269 T AT99966269 T AT 99966269T AT E333281 T1 ATE333281 T1 AT E333281T1
Authority
AT
Austria
Prior art keywords
agonists
antagonists
ptbr
treatment
conditions
Prior art date
Application number
AT99966269T
Other languages
English (en)
Inventor
Alison Joly
George F Schreiner
Lawrence W Stanton
R Tyler White
Original Assignee
Scios Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scios Inc filed Critical Scios Inc
Application granted granted Critical
Publication of ATE333281T1 publication Critical patent/ATE333281T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT99966269T 1998-12-18 1999-12-15 Agonisten und antagonisten von benzodiazepinrezeptoren des peripheren typs ATE333281T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11300898P 1998-12-18 1998-12-18
US13620399P 1999-05-26 1999-05-26

Publications (1)

Publication Number Publication Date
ATE333281T1 true ATE333281T1 (de) 2006-08-15

Family

ID=26810614

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99966269T ATE333281T1 (de) 1998-12-18 1999-12-15 Agonisten und antagonisten von benzodiazepinrezeptoren des peripheren typs

Country Status (7)

Country Link
US (2) US6342495B1 (de)
EP (1) EP1140107B1 (de)
AT (1) ATE333281T1 (de)
AU (1) AU2185100A (de)
DE (1) DE69932449T2 (de)
ES (1) ES2268894T3 (de)
WO (1) WO2000037086A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6300235B1 (en) * 1997-06-30 2001-10-09 Siemens Aktiengesellschaft Method of forming multi-level coplanar metal/insulator films using dual damascene with sacrificial flowable oxide
DE69932449T2 (de) * 1998-12-18 2007-03-15 Scios Inc., Fremont Agonisten und antagonisten von benzodiazepinrezeptoren des peripheren typs
RU2277096C2 (ru) * 2000-07-31 2006-05-27 ДАЙНИППОН СУМИТОМО ФАРМА Ко., ЛТД. Средства против слабоумия, содержащие производное 2-арил-8-оксодигидропурина в качестве активного ингредиента
JP2002306174A (ja) * 2001-04-11 2002-10-22 Univ Nihon 遺伝子のスクリーニング方法
CA2460117A1 (en) * 2001-09-11 2003-03-20 The Regents Of The University Of Colorado, A Body Corporate Expression profiling in the intact human heart
GB0213614D0 (en) * 2002-06-13 2002-07-24 Novartis Forschungsstiftlung Z Purified PKB Kinae and uses thereof
GB0418877D0 (en) * 2004-08-24 2004-09-29 Univ Edinburgh Heart
JP4362457B2 (ja) 2005-04-26 2009-11-11 独立行政法人科学技術振興機構 神経因性疼痛治療剤
WO2006138487A2 (en) * 2005-06-14 2006-12-28 The Johns Hopkins University Treatment of ischemia-induced arrhythmias
WO2007088528A1 (en) * 2006-02-03 2007-08-09 The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth, Near Dublin Microtubule targeting agents
WO2008001357A2 (en) * 2006-06-26 2008-01-03 Technion Research & Development Foundation Ltd. Methods and kits for diagnosing cancer
US9075060B2 (en) 2009-06-16 2015-07-07 Technion Research & Development Foundation Limited Methods for diagnosing oral or oral-pharyngeal cancer
CN101936986B (zh) * 2010-08-03 2013-03-06 中国农业大学 一种检测地西泮的方法及其专用化学发光免疫试剂盒
GB202017673D0 (en) * 2020-11-09 2020-12-23 Imperial College Innovations Ltd Treatment of pulmonary arterial hypertensive

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2582514B1 (fr) 1985-05-30 1988-02-19 Rhone Poulenc Sante Medicaments a base d'amides, nouveaux amides et leur preparation
FR2599740B1 (fr) 1986-06-05 1988-08-12 Rhone Poulenc Sante Derives de benzo(b)thiophene de benzo(b)furannecarboxamides, leurs procedes de preparation et les medicaments les contenant
DK273689A (da) 1988-06-06 1989-12-07 Sanofi Sa 4-amino-3-carboxyquinoliner og -naphthyridiner, fremgangsmaade til deres fremstilling og anvendelse deraf i laegemidler
FR2659329B1 (fr) 1990-03-09 1994-06-03 Adir Nouveaux derives d'imidazo [1,2-c] quinazoline, leur procede de preparation et les compositions pharmaceutiques les renfermant.
FR2669926A1 (fr) 1990-11-29 1992-06-05 Medgenix Group Sa Ligands specifiques des recepteurs aux benzodiazepines peripheriques.
FR2678269B1 (fr) 1991-06-27 1995-01-13 Synthelabo Derives de 1-(4-chlorophenyl)-2-[4-(2-phenylethyl)piperidin-1-yl]ethanol, leur application et leur preparation en therapeutique.
EP0524846A1 (de) 1991-06-27 1993-01-27 Synthelabo 2-(Piperidin-1-yl)ethanolderivate, ihre Herstellung und ihre Anwendung in der Therapie
US5550124A (en) 1991-12-10 1996-08-27 University Of Southern California Use of peripheral-type benzodiazpine sites for treatment of CNS trauma or disease
IL117659A (en) 1995-04-13 2000-12-06 Dainippon Pharmaceutical Co Substituted 2-phenyl pyrimidino amino acetamide derivative process for preparing the same and a pharmaceutical composition containing same
US5776946A (en) 1995-08-28 1998-07-07 Mcgeer; Patrick L. Peripheral benzodiazepine receptor ligands as antiinflammatory agents
WO1999058117A1 (fr) 1998-05-13 1999-11-18 Sanofi-Synthelabo Utilisation de composes reduisant l'apoptose
DE69932449T2 (de) * 1998-12-18 2007-03-15 Scios Inc., Fremont Agonisten und antagonisten von benzodiazepinrezeptoren des peripheren typs

Also Published As

Publication number Publication date
EP1140107B1 (de) 2006-07-19
US6342495B1 (en) 2002-01-29
ES2268894T3 (es) 2007-03-16
WO2000037086A1 (en) 2000-06-29
EP1140107A1 (de) 2001-10-10
US20030032637A1 (en) 2003-02-13
DE69932449D1 (de) 2006-08-31
DE69932449T2 (de) 2007-03-15
US6686354B2 (en) 2004-02-03
AU2185100A (en) 2000-07-12

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