ATE197549T1 - Methoden zur regulation der den magen und darm betreffenden motilitaet - Google Patents

Methoden zur regulation der den magen und darm betreffenden motilitaet

Info

Publication number
ATE197549T1
ATE197549T1 AT94927398T AT94927398T ATE197549T1 AT E197549 T1 ATE197549 T1 AT E197549T1 AT 94927398 T AT94927398 T AT 94927398T AT 94927398 T AT94927398 T AT 94927398T AT E197549 T1 ATE197549 T1 AT E197549T1
Authority
AT
Austria
Prior art keywords
methods
motilitaty
intestinate
stomach
affecting
Prior art date
Application number
AT94927398T
Other languages
English (en)
Inventor
Orville G Kolterman
Andrew A Young
Timothy J Rink
Kathleen Keiting Brown
Original Assignee
Amylin Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amylin Pharmaceuticals Inc filed Critical Amylin Pharmaceuticals Inc
Application granted granted Critical
Publication of ATE197549T1 publication Critical patent/ATE197549T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/23—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nutrition Science (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
AT94927398T 1993-09-07 1994-09-07 Methoden zur regulation der den magen und darm betreffenden motilitaet ATE197549T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11838193A 1993-09-07 1993-09-07
PCT/US1994/010225 WO1995007098A1 (en) 1993-09-07 1994-09-07 Methods for regulating gastrointestinal motility

Publications (1)

Publication Number Publication Date
ATE197549T1 true ATE197549T1 (de) 2000-12-15

Family

ID=22378228

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94927398T ATE197549T1 (de) 1993-09-07 1994-09-07 Methoden zur regulation der den magen und darm betreffenden motilitaet

Country Status (23)

Country Link
US (4) US6114304A (de)
EP (1) EP0717635B1 (de)
JP (2) JP3821839B2 (de)
KR (2) KR100391399B1 (de)
CN (1) CN1134110A (de)
AT (1) ATE197549T1 (de)
AU (1) AU7685894A (de)
BG (1) BG100463A (de)
BR (1) BR9407424A (de)
CA (1) CA2171207C (de)
CZ (1) CZ69596A3 (de)
DE (1) DE69426304T2 (de)
DK (1) DK0717635T3 (de)
ES (1) ES2154299T3 (de)
GR (1) GR3035387T3 (de)
HU (1) HUT73490A (de)
NO (1) NO960899L (de)
PT (1) PT717635E (de)
RU (1) RU2177331C2 (de)
SG (1) SG98356A1 (de)
SK (1) SK31496A3 (de)
WO (1) WO1995007098A1 (de)
ZA (1) ZA946881B (de)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7138486B2 (en) 1986-05-05 2006-11-21 The General Hospital Corporation Insulinotropic hormone derivatives and uses thereof
US6849708B1 (en) 1986-05-05 2005-02-01 The General Hospital Corporation Insulinotropic hormone and uses thereof
US5614492A (en) * 1986-05-05 1997-03-25 The General Hospital Corporation Insulinotropic hormone GLP-1 (7-36) and uses thereof
HU222249B1 (hu) * 1991-03-08 2003-05-28 Amylin Pharmaceuticals Inc. Eljárás amilin agonista peptidszármazékok és ezeket tartalmazó gyógyszerkészítmények előállítására
US6284727B1 (en) 1993-04-07 2001-09-04 Scios, Inc. Prolonged delivery of peptides
WO1995007098A1 (en) * 1993-09-07 1995-03-16 Amylin Pharmaceuticals, Inc. Methods for regulating gastrointestinal motility
US6143718A (en) * 1995-06-07 2000-11-07 Amylin Pharmaceuticals, Inc. Treatment of Type II diabetes mellutis with amylin agonists
DE69740096D1 (de) * 1996-08-08 2011-02-17 Amylin Pharmaceuticals Inc Pharmazeutische Zusammensetzung mit einem Exendin-4-Peptid
JP4798814B2 (ja) 1997-01-07 2011-10-19 アミリン・ファーマシューティカルズ，インコーポレイテッド 食物摂取低減用のエキセンジンおよびそのアゴニストの使用
US7101853B2 (en) * 1997-05-06 2006-09-05 Amylin Pharmaceuticals, Inc. Method for treating or preventing gastritis using amylin or amylin agonists
US7910548B2 (en) * 1997-06-06 2011-03-22 Amylin Pharmaceuticals, Inc. Methods for treating obesity
DE69943039D1 (de) 1998-02-13 2011-01-27 Amylin Pharmaceuticals Inc Neue verbindungen mit gemischter amylin aktivität
US6936584B1 (en) 1998-02-13 2005-08-30 Amylin Pharmaceuticals, Inc. Mixed amylin activity compounds
JP2002538084A (ja) 1999-01-14 2002-11-12 アミリン・ファーマシューティカルズ，インコーポレイテッド グルカゴンを抑制する方法
US7399489B2 (en) 1999-01-14 2008-07-15 Amylin Pharmaceuticals, Inc. Exendin analog formulations
RU2242244C2 (ru) 1999-01-14 2004-12-20 Амилин Фармасьютикалз, Инк. Новые композиции агонистов эксендина и способы их введения
US6924264B1 (en) 1999-04-30 2005-08-02 Amylin Pharmaceuticals, Inc. Modified exendins and exendin agonists
US6528486B1 (en) 1999-07-12 2003-03-04 Zealand Pharma A/S Peptide agonists of GLP-1 activity
US6451806B2 (en) 1999-09-29 2002-09-17 Adolor Corporation Methods and compositions involving opioids and antagonists thereof
US6469030B2 (en) 1999-11-29 2002-10-22 Adolor Corporation Methods for the treatment and prevention of ileus
ES2440190T3 (es) 2000-03-03 2014-01-28 C. R. Bard, Inc. Dispositivo endoscópico de aposición de tejido con múltiples puertos de succión
US7220266B2 (en) 2000-05-19 2007-05-22 C. R. Bard, Inc. Tissue capturing and suturing device and method
US6451813B1 (en) 2001-01-26 2002-09-17 R. T. Alamo Ventures I, Llc Treatment of gastroparesis in certain patient groups
AU2003273318A1 (en) * 2002-09-12 2004-04-30 University Of Chicago Monitoring and diagnosis of gastric emptying and gastroparesis
AU2003278929A1 (en) * 2002-10-18 2004-05-13 Amylin Pharmaceuticals, Inc. Treatment of pancreatitis with amylin
US7655618B2 (en) * 2002-12-27 2010-02-02 Diobex, Inc. Compositions and methods for the prevention and control of insulin-induced hypoglycemia
NZ541365A (en) * 2002-12-27 2009-09-25 Diobex Inc Compositions and methods for the prevention and control of insulin-induced hypoglycemia
US20070275877A1 (en) * 2003-08-29 2007-11-29 Amylin Pharmaceuticals, Inc. Methods for Treating or Ameliorating Ghrelin-Associated Diseases and Disorders
RU2385878C2 (ru) 2004-02-11 2010-04-10 Амилин Фармасьютикалз, Инк. Пептид, обладающий свойствами амилина (варианты), и его применение (варианты)
US7399744B2 (en) * 2004-03-04 2008-07-15 Amylin Pharmaceuticals, Inc. Methods for affecting body composition
RU2433133C2 (ru) * 2004-03-09 2011-11-10 Майкробиа, Инк. Полипептид для увеличения активности рецептора гуанилатциклазы, фармацевтическая композиция, способ лечения желудочно-кишечного расстройства у пациента, способ повышения активности рецептора гуанилатциклазы у пациента, способ лечения висцеральной боли, способ получения полипептида (варианты), изолированная молекула нуклеиновой кислоты, бактериальный вектор экспрессии и изолированная бактериальная клетка
US7878978B2 (en) 2004-03-18 2011-02-01 University Of Pittsburgh- Of The Commonwealth System Of Higher Education Use of relaxin to increase arterial compliance
US8172857B2 (en) 2004-08-27 2012-05-08 Davol, Inc. Endoscopic tissue apposition device and method of use
US8394765B2 (en) * 2004-11-01 2013-03-12 Amylin Pharmaceuticals Llc Methods of treating obesity with two different anti-obesity agents
DK1814590T4 (da) 2004-11-01 2014-02-24 Amylin Pharmaceuticals Llc Behandling af obesitet og beslægtede sygdomme.
KR20080003849A (ko) 2005-03-31 2008-01-08 아밀린 파마슈티칼스, 인크. 비만 및 섭식 장애의 조절, 예방 및 치료를 위한 조성물 및방법
EP2241327A1 (de) 2006-03-15 2010-10-20 Novo Nordisk A/S Mischung von Amylin und Insulin
JP2009530407A (ja) * 2006-03-23 2009-08-27 アミリン・ファーマシューティカルズ，インコーポレイテッド 代謝性疾患の治療用のエンドセリン及びエンドセリン受容体アゴニスト
US20090181890A1 (en) * 2006-03-31 2009-07-16 Amylin Pharmaceuticals , Inc. Amylin and Amylin Agonists for Treating Psychiatric Diseases and Disorders
RU2314106C1 (ru) * 2006-07-07 2008-01-10 ФГОУ ВПО "Белгородская государственная сельскохозяйственная академия" Способ угнетения моторной функции пищеварительного тракта
EP2120985B1 (de) 2007-02-05 2012-06-27 Amylin Pharmaceuticals, Inc. FN-38 Peptide zur Verwendung bei der Behandlung Psychotischer- und Angsterkrankungen
EP2219664A1 (de) * 2007-11-14 2010-08-25 Amylin Pharmaceuticals, Inc. Verfahren zur behandlung von fettsucht und erkrankungen und störungen im zusammenhang mit fettsucht
EP2405934B1 (de) 2009-03-12 2014-03-26 Nordic Bioscience A/S Behandlung von Diabetes und metabolischem Syndrom
WO2010107874A2 (en) * 2009-03-17 2010-09-23 Amylin Pharmaceuticals, Inc. Methods for affecting body composition using amylin agonists
CN103003300B (zh) 2010-04-27 2017-06-09 西兰制药公司 Glp‑1受体激动剂和胃泌素的肽缀合物及其用途
KR20140100947A (ko) 2011-11-03 2014-08-18 질랜드 파마 에이/에스 Ｇｌｐ-1 수용체 효능제 펩타이드 가스트린 접합체들
NZ704043A (en) 2012-07-23 2017-07-28 Zealand Pharma As Glucagon analogues
TWI608013B (zh) 2012-09-17 2017-12-11 西蘭製藥公司 升糖素類似物
AR098065A1 (es) 2013-10-17 2016-04-27 Zealand Pharma As Análogos de glucagón acilados
US9988429B2 (en) 2013-10-17 2018-06-05 Zealand Pharma A/S Glucagon analogues
AU2014345570B2 (en) 2013-11-06 2019-01-24 Zealand Pharma A/S Glucagon-GLP-1-GIP triple agonist compounds
CA2929459C (en) 2013-11-06 2022-05-03 Zealand Pharma A/S Gip-glp-1 dual agonist compounds and methods
WO2015196174A1 (en) 2014-06-20 2015-12-23 Greene Howard E Infusion delivery devices and methods
EP3212218B1 (de) 2014-10-29 2021-06-30 Zealand Pharma A/S Gip-agonisten-verbindungen und -verfahren
AR103954A1 (es) 2015-03-18 2017-06-14 Zealand Pharma As Análogos de amilina
PL3283507T3 (pl) 2015-04-16 2020-05-18 Zealand Pharma A/S Acylowany analog glukagonu
AR109514A1 (es) 2016-09-09 2018-12-19 Zealand Pharma As Análogos de amilina
KR102502040B1 (ko) 2016-12-09 2023-02-24 질랜드 파마 에이/에스 아실화 glp-1/glp-2 이중 효능제
EP3562500B1 (de) 2016-12-27 2023-07-19 Adocia Zusammensetzungen in form einer injizierbaren wässrigen lösung mit amylin, einem amylin-rezeptor-agonist oder einem amylin-analogon und einer copolyaminosäure
PL4019039T3 (pl) 2017-07-27 2024-03-18 Adocia Kompozycje w postaci wodnego roztworu do wstrzykiwania zawierające co najmniej insulinę ludzką a21g i co najmniej jeden supresor glukagonu o działaniu posiłkowym
US20190275108A1 (en) 2017-12-07 2019-09-12 Adocia Compositions in the form of an injectable aqueous solution comprising amylin, an amylin receptor agonist or an amylin analogue and a co-polyamino acid
IL275146B2 (en) 2017-12-07 2025-01-01 Adocia Preparations in the form of an aqueous solution for injection comprising amylin, an amylin receptor agonist or an amylin analog and a copolyamino acid
CN111683674A (zh) 2017-12-07 2020-09-18 阿道恰公司 包含胰淀素、胰淀素激动剂受体或胰淀素类似物和共聚氨基酸的可注射水溶液形式的组合物
EP3740195A1 (de) 2017-12-07 2020-11-25 Adocia Zusammensetzungen in form einer injizierbaren wässrigen lösung mit amylin, einem amylin-rezeptor-agonist oder einem amylin-analogon und einer copolyaminosäure
FR3083085B1 (fr) 2018-06-29 2020-10-02 Adocia Compositions sous forme d'une solution aqueuse injectable comprenant de l'amyline, un agoniste au recepteur de l'amyline ou un analogue d'amyline et un co-polyaminoacide
FR3083086A1 (fr) 2018-06-29 2020-01-03 Adocia Compositions sous forme d'une solution aqueuse injectable comprenant de l'amyline, un agoniste au recepteur de l'amyline ou un analogue d'amyline et un co-polyaminoacide
FR3084586B1 (fr) 2018-08-03 2020-11-06 Adocia Compositions sous forme d'une solution aqueuse injectable comprenant de l'amyline, un agoniste au recepteur de l'amyline ou un analogue d'amyline et un compose amphiphile porteur de radicaux hydrophobes
WO2020180534A1 (en) 2019-03-01 2020-09-10 President And Fellows Of Harvard College Methods and compositions for protein delivery
CA3237751A1 (en) * 2021-11-10 2023-05-19 Tyler Brown Ionic liquid compositions
CN118742204A (zh) * 2022-01-11 2024-10-01 国立大学法人东京大学 食用鱼的生产方法及食用鱼
IL312600B2 (en) 2022-05-30 2025-12-01 Zealand Pharma As Liquid formulations of amylin analogs

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4451394A (en) * 1982-10-25 1984-05-29 American Home Products Corporation Dodecapeptides preventing glucose and triglyceride assimilation
US4530838A (en) * 1983-07-08 1985-07-23 The Salk Institute For Biological Studies Synthetic calcitonin-gene-related peptides for lowering blood pressure or gastric acid secretion in mammals
US4690486A (en) * 1985-04-29 1987-09-01 Texas Instruments Incorporated Four position interlacing apparatus
GB8720115D0 (en) * 1987-08-26 1987-09-30 Cooper G J S Treatment of diabetes mellitus
US5367052A (en) * 1987-04-27 1994-11-22 Amylin Pharmaceuticals, Inc. Amylin peptides
GB8709871D0 (en) * 1987-04-27 1987-06-03 Turner R C Peptides
US5266561A (en) * 1988-01-11 1993-11-30 Amylin Pharmaceuticals, Inc. Treatment of type 2 diabetes mellitus
US5175145A (en) * 1988-08-26 1992-12-29 Amylin Pharmaceuticals, Inc. Treatment of diabetes mellitus with amylin agonists
US5166192A (en) 1989-05-09 1992-11-24 Mathias John R Treatment of motility disorders with a GnRH analog
US5260275A (en) * 1990-08-14 1993-11-09 Amylin Pharmaceuticals, Inc. Hypoglycemics
US5187154A (en) * 1990-12-13 1993-02-16 Board Of Regents, The University Of Texas System Diagnosis and treatment of humans with diabetes or at risk to develop diabetes
US5234906A (en) * 1991-01-10 1993-08-10 Amylin Pharmaceuticals, Inc. Hyperglycemic compositions
US5264372A (en) * 1991-03-15 1993-11-23 Amylin Pharmaceuticals, Inc. Receptor-based screening methods for amylin agonists and antagonists
HU222249B1 (hu) * 1991-03-08 2003-05-28 Amylin Pharmaceuticals Inc. Eljárás amilin agonista peptidszármazékok és ezeket tartalmazó gyógyszerkészítmények előállítására
ES2108122T3 (es) * 1991-05-24 1997-12-16 Amylin Pharmaceuticals Inc Composicion a base de amilina o de un analogo de amilina conteniendo opcionalmente insulina, para el tratamiento de la anorexia y de las patologias asociadas.
US5580953A (en) * 1991-08-14 1996-12-03 Amylin Pharmaceuticals, Inc. Amylin antagonist peptides and uses therefor
EP0567626B1 (de) * 1991-11-19 2001-09-19 Amylin Pharmaceuticals, Inc. Peptide als Amylin-Agonisten und ihre Verwendung
US5376638A (en) * 1992-09-01 1994-12-27 Amylin Pharmaceuticals, Inc. Methods for treating renin-related disorders with amylin antagonists
WO1994020116A1 (en) * 1993-03-10 1994-09-15 University Of Alabama Research Foundation Artificial primers for glycogen synthesis
WO1995007098A1 (en) * 1993-09-07 1995-03-16 Amylin Pharmaceuticals, Inc. Methods for regulating gastrointestinal motility
US6143718A (en) * 1995-06-07 2000-11-07 Amylin Pharmaceuticals, Inc. Treatment of Type II diabetes mellutis with amylin agonists

Also Published As

Publication number Publication date
US6114304A (en) 2000-09-05
DE69426304T2 (de) 2001-03-15
CA2171207C (en) 2010-03-30
JPH09502443A (ja) 1997-03-11
NO960899L (no) 1996-05-06
CA2171207A1 (en) 1995-03-16
JP2004331674A (ja) 2004-11-25
GR3035387T3 (en) 2001-05-31
EP0717635B1 (de) 2000-11-15
BG100463A (en) 1997-03-31
US5795861A (en) 1998-08-18
KR20040004418A (ko) 2004-01-13
BR9407424A (pt) 1996-04-09
US20040097415A1 (en) 2004-05-20
DK0717635T3 (da) 2000-12-11
US6608029B1 (en) 2003-08-19
HU9600558D0 (en) 1996-05-28
KR100429966B1 (ko) 2004-05-04
AU7685894A (en) 1995-03-27
SK31496A3 (en) 1998-06-03
HUT73490A (en) 1996-08-28
US7407934B2 (en) 2008-08-05
JP3821839B2 (ja) 2006-09-13
DE69426304D1 (de) 2000-12-21
EP0717635A1 (de) 1996-06-26
KR100391399B1 (ko) 2004-02-11
WO1995007098A1 (en) 1995-03-16
ZA946881B (en) 1995-10-30
RU2177331C2 (ru) 2001-12-27
CZ69596A3 (en) 1997-06-11
CN1134110A (zh) 1996-10-23
ES2154299T3 (es) 2001-04-01
NO960899D0 (no) 1996-03-06
PT717635E (pt) 2001-04-30
SG98356A1 (en) 2003-09-19

Similar Documents

Publication Publication Date Title
DE69426304D1 (de) Methoden zur regulation der den magen und darm betreffenden motilitaet
CA2262647A1 (en) Methods for regulating gastrointestinal motility
CA2274596A1 (en) Compositions and methods for enhancing intestinal function
EA200000445A1 (ru) Способы лечения состояния гиперкоагуляции или приобретенной недостаточности белка c
NZ504258A (en) Exendin 3 and 4 agonist compounds for the treatment of diabetes
CY1107752T1 (el) Xρηση των εξενδινων και αγωνιστων τους για τη θεραπεια του σακχαρωδους διαβητη της κυησης
EP2295453A3 (de) Appetithemmendes Peptid, Zusammensetzung und Verwendung
WO1997040072A3 (en) Adam proteins and uses thereof
GR3019514T3 (en) Pharmaceutical preparation for the treatment of prolonged coagulation time
CA2340320A1 (en) Use of an angiogenic factor for the treatment of microascular angiopathies
TR200101149T2 (tr) Dış retina bozukluklarının tedavisi.
UA50761C2 (uk) Спосіб запобігання та/або лікування серцевих захворювань, фармацевтична композиція та спосіб запобігання та/або лікування серцевої недостатності та дисфункції шлуночків в організмі теплокровної тварини
EP1417971A3 (de) Verwendung eines angiogenen Faktors zur Behandlung von mikrovaskulären Angiopathien
DE3378979D1 (en) 1-acyl-3-pyridylmethylguanidines and their use as antihypertensive agents
IL129482A0 (en) Method of enhancing the delivery of growth factors
DE69734349D1 (de) Behandlung von knochenleiden mit adrenomedullin
KR900017599A (ko) 종양 치료용 약학 조성물
MX2025007118A (es) Metodos de tratamiento con tradipitant.
DE69614577D1 (de) Polyamin-antagonisten enthaltende intraokulare irrigationslösung
王國興 et al. Scaphoid Nonunion Treated with Matti-Russe Technique and Internal Fixation
UA29280A (uk) Спосіб лікування флегмони шлунку
UA23123A (uk) Спосіб хірургічhого лікуваhhя hавколососочкових виразок дваhадцятипалої кишки
MD686G2 (ro) Metodă de tratament al reflux- esofagitei
UA31276A (uk) Спосіб діагностики хламідіозу і мікоплазмозу у хворих на ранній сифіліс
UA32280A (uk) Спосіб формування тонко-товстокишкового анастомозу бік у бік

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification