ATE333468T1 - Melanocortin 1 rezeptorselektive verbindungen - Google Patents

Melanocortin 1 rezeptorselektive verbindungen

Info

Publication number: ATE333468T1
Authority: AT; Austria
Prior art keywords: aminoacid; alkyl; compound; receptors; polypeptide
Prior art date: 1998-05-05

Application number

AT99919433T

Other languages

English (en)

Inventor

Michael Szardenings

Ruta Muceniece

Ilze Mutule

Felikss Mutulis

Jarl Wikberg

Original Assignee

Action Pharma As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-05-05

Filing date

1999-05-05

Publication date

2006-08-15

1999-05-05 Application filed by Action Pharma As filed Critical Action Pharma As

2006-08-15 Application granted granted Critical

2006-08-15 Publication of ATE333468T1 publication Critical patent/ATE333468T1/de

Links

150000001875 compounds Chemical class 0.000 title abstract 4
102000008314 Type 1 Melanocortin Receptor Human genes 0.000 title abstract 3
108010021428 Type 1 Melanocortin Receptor Proteins 0.000 title abstract 3
235000001014 amino acid Nutrition 0.000 abstract 4
150000001413 amino acids Chemical class 0.000 abstract 4
125000000217 alkyl group Chemical group 0.000 abstract 3
108020004414 DNA Proteins 0.000 abstract 2
125000000524 functional group Chemical group 0.000 abstract 2
108020001507 fusion proteins Proteins 0.000 abstract 2
102000037865 fusion proteins Human genes 0.000 abstract 2
125000002887 hydroxy group Chemical class [H]O* 0.000 abstract 2
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
229920001184 polypeptide Polymers 0.000 abstract 2
102000004196 processed proteins & peptides Human genes 0.000 abstract 2
108090000765 processed proteins & peptides Proteins 0.000 abstract 2
102000053602 DNA Human genes 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
230000004968 inflammatory condition Effects 0.000 abstract 1
230000005764 inhibitory process Effects 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
230000000638 stimulation Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- C07K14/68—Melanocyte-stimulating hormone [MSH]
- C07K14/685—Alpha-melanotropin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Dermatology (AREA)
Endocrinology (AREA)
Toxicology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Pain & Pain Management (AREA)
Pulmonology (AREA)
Rheumatology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)
Pyrane Compounds (AREA)
Cosmetics (AREA)

AT99919433T 1998-05-05 1999-05-05 Melanocortin 1 rezeptorselektive verbindungen ATE333468T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
SE9801571A SE9801571D0 (sv)	1998-05-05	1998-05-05	Melanokortin-1-receptorselektiva föreningar

Publications (1)

Publication Number	Publication Date
ATE333468T1 true ATE333468T1 (de)	2006-08-15

Family

ID=20411194

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99919433T ATE333468T1 (de)	1998-05-05	1999-05-05	Melanocortin 1 rezeptorselektive verbindungen

Country Status (14)

Country	Link
US (2)	US7008925B1 (de)
EP (2)	EP1075492B1 (de)
JP (1)	JP4584450B2 (de)
AT (1)	ATE333468T1 (de)
AU (1)	AU765120B2 (de)
CA (1)	CA2327550A1 (de)
CY (1)	CY1105654T1 (de)
DE (1)	DE69932424T2 (de)
DK (1)	DK1075492T3 (de)
ES (1)	ES2268862T3 (de)
NZ (1)	NZ507792A (de)
PT (1)	PT1075492E (de)
SE (1)	SE9801571D0 (de)
WO (1)	WO1999057148A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU757658B2 (en) *	1998-03-09	2003-02-27	Zealand Pharma A/S	Pharmacologically active peptide conjugates having a reduced tendency towards enzymatic hydrolysis
SE9801571D0 (sv)	1998-05-05	1998-05-05	Wapharm Ab	Melanokortin-1-receptorselektiva föreningar
US7176279B2 (en)	2000-06-28	2007-02-13	Palatin Technologies, Inc.	Cyclic peptide compositions and methods for treatment of sexual dysfunction
WO2002006316A2 (en) *	2000-07-14	2002-01-24	Zycos, Inc.	Alpha-msh related compounds and methods of use
AU2002238106A1 (en)	2001-02-13	2002-08-28	Palatin Technologies, Inc.	Melanocortin metallopeptides for treatment of sexual dysfunction
DE10106852A1 (de) *	2001-02-14	2002-09-05	T Luger	Entzündungshemmende Verbindungen
US20080009019A1 (en) *	2001-06-13	2008-01-10	Smithkline Beecham Corporation	High throughput method for screening candidate compounds for biological activity
FR2826580B1 (fr) *	2001-06-29	2005-09-30	Oreal	Utilisation du tripeptide lys-pro-val (kpv) pour favoriser le renouvellement epidermique et la micro-cicatrisation cutanee superficielle et/ou ameliorer l'aspect esthetique des plaies et cicatrices
FR2826581B1 (fr) *	2001-06-29	2005-10-07	Oreal	Utilisation du tripeptide lys-pro-val (kpv) dans le traitement des melanomes
AU2005335905C1 (en)	2005-08-26	2011-12-22	Abbvie Inc.	Therapeutically active alpha-MSH analogues
WO2009039983A2 (en) *	2007-09-11	2009-04-02	Mondobiotech Laboratories Ag	Use of a peptide as a therapeutic agent
TW201002340A (en) *	2008-06-09	2010-01-16	Palatin Technologies Inc	Melanocortin receptor-specific peptides for treatment of obesity
WO2009152079A1 (en)	2008-06-09	2009-12-17	Palatin Technologies, Inc.	Melanocortin receptor-specific peptides for treatment of sexual dysfunction
EA020959B1 (ru)	2009-06-08	2015-03-31	Палатин Текнолоджиз, Инк.	Пептиды, специфичные к меланокортиновым рецепторам
EP2440572B1 (de)	2009-06-08	2017-04-05	Palatin Technologies, Inc.	Lactam-gebrückte melanocortinrezeptorspezifische peptide
UY32690A (es)	2009-06-08	2011-01-31	Astrazeneca Ab	Péptidos específicos para receptores de melanocortina
BR112012011780A2 (pt)	2009-11-23	2019-09-24	Palatin Technologies, Inc	peptídeo linear,composição farmacêutica,métodopara tratamento de umadoença,indicação,condição ou sídrome mediadsa por receptor de melanocortina emum mamífero humano ou não humano e método para tratamento de uma condição responsiva ás alterações em função de receptor de melanocortina em um mamifero humano ou não humano
EA021897B1 (ru)	2009-11-23	2015-09-30	Палатин Текнолоджиз, Инк.	Циклические пептиды, специфичные к рецептору меланокортина-1
JP5715104B2 (ja) *	2012-09-27	2015-05-07	アブビーインコーポレイティド	治療的に活性なα−ＭＳＨアナログ
WO2014060606A1 (en)	2012-10-19	2014-04-24	Txp Pharma Gmbh	Alpha- and gamma-msh analogues
WO2015162485A1 (en)	2014-04-22	2015-10-29	Txp Pharma Gmbh	Peptide analogues with branched amino acid probe(s)
US9939338B2 (en)	2015-02-19	2018-04-10	Stmicroelectronics S.R.L.	Pressure sensing device with cavity and related methods
WO2017019664A1 (en)	2015-07-28	2017-02-02	University Of Iowa Research Foundation	Compositions and methods of treating cancer
US11179484B2 (en) *	2016-06-24	2021-11-23	University Of Iowa Research Foundation	Compositions and methods of treating melanoma
US11590209B2 (en)	2020-01-21	2023-02-28	Palatin Technologies, Inc.	Use of bremelanotide in patients with controlled hypertension
US11529335B2 (en)	2020-07-31	2022-12-20	University Of Iowa Research Foundation	Compositions and methods for treating cancer

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4288627A (en)	1980-02-12	1981-09-08	Phillips Petroleum Company	Oxidation of thiols employing cobalt molybdate/triethylamine catalyst
CA2082279C (en)	1990-05-09	2007-09-04	Grethe Rasmussen	Cellulase preparation comprising an endoglucanase enzyme
US5814603A (en)	1992-06-12	1998-09-29	Affymax Technologies N.V.	Compounds with PTH activity
US5731408A (en)	1995-04-10	1998-03-24	Arizona Board Of Regents On Behalf Of The University Of Arizona	Peptides having potent antagonist and agonist bioactivities at melanocortin receptors
AU757658B2 (en)	1998-03-09	2003-02-27	Zealand Pharma A/S	Pharmacologically active peptide conjugates having a reduced tendency towards enzymatic hydrolysis
SE9801571D0 (sv)	1998-05-05	1998-05-05	Wapharm Ab	Melanokortin-1-receptorselektiva föreningar
EP1076066A1 (de)	1999-07-12	2001-02-14	Zealand Pharmaceuticals A/S	Peptide zur Senkung des Blutglukosespiegels
GB9927346D0 (en)	1999-11-18	2000-01-12	Melacure Therapeutics Ab	Method for analysis and design of entities of a chemical or biochemical nature
GB0012370D0 (en)	2000-05-22	2000-07-12	Quadrant Holdings Cambridge	Peptoids
AU2005335905C1 (en)	2005-08-26	2011-12-22	Abbvie Inc.	Therapeutically active alpha-MSH analogues

1998
- 1998-05-05 SE SE9801571A patent/SE9801571D0/xx unknown
1999
- 1999-05-05 ES ES99919433T patent/ES2268862T3/es not_active Expired - Lifetime
- 1999-05-05 DE DE69932424T patent/DE69932424T2/de not_active Expired - Lifetime
- 1999-05-05 EP EP99919433A patent/EP1075492B1/de not_active Expired - Lifetime
- 1999-05-05 WO PCT/GB1999/001388 patent/WO1999057148A1/en not_active Ceased
- 1999-05-05 DK DK99919433T patent/DK1075492T3/da active
- 1999-05-05 EP EP05028298A patent/EP1693382A3/de not_active Withdrawn
- 1999-05-05 US US09/674,733 patent/US7008925B1/en not_active Expired - Fee Related
- 1999-05-05 NZ NZ507792A patent/NZ507792A/en unknown
- 1999-05-05 AT AT99919433T patent/ATE333468T1/de active
- 1999-05-05 JP JP2000547116A patent/JP4584450B2/ja not_active Expired - Fee Related
- 1999-05-05 CA CA002327550A patent/CA2327550A1/en not_active Abandoned
- 1999-05-05 PT PT99919433T patent/PT1075492E/pt unknown
- 1999-05-05 AU AU37222/99A patent/AU765120B2/en not_active Ceased
2005
- 2005-12-29 US US11/319,584 patent/US7662782B2/en not_active Expired - Fee Related
2006
- 2006-10-10 CY CY20061101449T patent/CY1105654T1/el unknown

Also Published As

Publication number	Publication date
AU3722299A (en)	1999-11-23
EP1693382A2 (de)	2006-08-23
NZ507792A (en)	2003-10-31
SE9801571D0 (sv)	1998-05-05
DE69932424D1 (de)	2006-08-31
EP1075492A1 (de)	2001-02-14
CY1105654T1 (el)	2010-12-22
JP4584450B2 (ja)	2010-11-24
ES2268862T3 (es)	2007-03-16
EP1693382A3 (de)	2006-11-08
EP1075492B1 (de)	2006-07-19
JP2002513555A (ja)	2002-05-14
DE69932424T2 (de)	2007-02-22
DK1075492T3 (da)	2006-12-04
US20070027086A1 (en)	2007-02-01
PT1075492E (pt)	2006-11-30
US7662782B2 (en)	2010-02-16
US7008925B1 (en)	2006-03-07
WO1999057148A1 (en)	1999-11-11
CA2327550A1 (en)	1999-11-11
AU765120B2 (en)	2003-09-11

Legal Events

Date

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Title

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2007-06-15

UEP

Publication of translation of european patent specification

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DK1075492T3 (da)	2006-12-04	Melanocortin 1-receptorselektive forbindelser
MY142065A (en)	2010-08-30	Arylalkylamines, process for preparing them and pharmaceutical compositions containing them
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TW368500B (en)	1999-09-01	1-Benzenesulfonyl-1,3-dihydro-2H-benzimidazol-2-one derivatives
KR900006363A (ko)	1990-05-08	신규한 펩티다제 억제제
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KR960031466A (ko)	1996-09-17	테트라하이드로나프탈렌 유도체
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NO971789L (no)	1997-06-19	Di-tert-butylfenolforbindelser med heterocyklisk enhet for anvendelse som antiinflammatoriske midler
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ES2073258T3 (es)	1995-08-01	Nuevos derivados de la urea, su preparacion y su aplicacion en terapeutica.
HU896606D0 (en)	1990-02-28	Process for the preparation of aminoacid derivatives inhibiting enzymes and pharmaceutical compositions thereof
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KR910000791A (ko)	1991-01-30	뉴로키닌 a 길항제
PT80670B (de)	1987-05-08	Neue 8-alkylthio-2-piperazino-pyrimido<5,4d>pyrimidine ihre herstellung und diese verbindungen enthaltende arzneimittel
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