ATE333885T1 - Verwendung von sulodexid zur behandlung von reizdarm - Google Patents

Verwendung von sulodexid zur behandlung von reizdarm

Info

Publication number: ATE333885T1
Authority: AT; Austria
Prior art keywords: composition; sulodexide; clathrate; solvate; hydrate
Prior art date: 2001-05-17

Application number

AT02733192T

Other languages

English (en)

Inventor

Michael Spero

Noa Shelach

Morris Laster

Original Assignee

Keryx Biopharmceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-05-17

Filing date

2002-05-19

Publication date

2006-08-15

2002-05-19 Application filed by Keryx Biopharmceuticals Inc filed Critical Keryx Biopharmceuticals Inc

2006-08-15 Application granted granted Critical

2006-08-15 Publication of ATE333885T1 publication Critical patent/ATE333885T1/de

Links

GRYSXUXXBDSYRT-WOUKDFQISA-N (2r,3r,4r,5r)-2-(hydroxymethyl)-4-methoxy-5-[6-(methylamino)purin-9-yl]oxolan-3-ol Chemical compound C1=NC=2C(NC)=NC=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1OC GRYSXUXXBDSYRT-WOUKDFQISA-N 0.000 title abstract 2
229920000439 Sulodexide Polymers 0.000 title abstract 2
229960003491 sulodexide Drugs 0.000 title abstract 2
150000003839 salts Chemical class 0.000 abstract 2
239000012453 solvate Substances 0.000 abstract 2
NBGAYCYFNGPNPV-UHFFFAOYSA-N 2-aminooxybenzoic acid Chemical class NOC1=CC=CC=C1C(O)=O NBGAYCYFNGPNPV-UHFFFAOYSA-N 0.000 abstract 1
229920000045 Dermatan sulfate Polymers 0.000 abstract 1
208000022559 Inflammatory bowel disease Diseases 0.000 abstract 1
QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
239000003242 anti bacterial agent Substances 0.000 abstract 1
229940088710 antibiotic agent Drugs 0.000 abstract 1
239000000935 antidepressant agent Substances 0.000 abstract 1
229940005513 antidepressants Drugs 0.000 abstract 1
239000003124 biologic agent Substances 0.000 abstract 1
AVJBPWGFOQAPRH-FWMKGIEWSA-L dermatan sulfate Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@H](OS([O-])(=O)=O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](C([O-])=O)O1 AVJBPWGFOQAPRH-FWMKGIEWSA-L 0.000 abstract 1
229940051593 dermatan sulfate Drugs 0.000 abstract 1
229940124641 pain reliever Drugs 0.000 abstract 1
150000004666 short chain fatty acids Chemical class 0.000 abstract 1
235000021391 short chain fatty acids Nutrition 0.000 abstract 1
150000003431 steroids Chemical class 0.000 abstract 1
MNRILEROXIRVNJ-UHFFFAOYSA-N tioguanine Chemical class N1C(N)=NC(=S)C2=NC=N[C]21 MNRILEROXIRVNJ-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Molecular Biology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Dermatology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT02733192T 2001-05-17 2002-05-19 Verwendung von sulodexid zur behandlung von reizdarm ATE333885T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US29166701P	2001-05-17	2001-05-17

Publications (1)

Publication Number	Publication Date
ATE333885T1 true ATE333885T1 (de)	2006-08-15

Family

ID=23121293

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT02733192T ATE333885T1 (de)	2001-05-17	2002-05-19	Verwendung von sulodexid zur behandlung von reizdarm

Country Status (12)

Country	Link
US (1)	US20030008844A1 (de)
EP (1)	EP1392329B1 (de)
JP (1)	JP2004534087A (de)
AT (1)	ATE333885T1 (de)
AU (1)	AU2002304265B2 (de)
CA (1)	CA2447280A1 (de)
DE (1)	DE60213404T2 (de)
DK (1)	DK1392329T3 (de)
IL (1)	IL158903A0 (de)
MX (1)	MXPA03010493A (de)
NZ (1)	NZ530020A (de)
WO (1)	WO2003002129A1 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
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IL150907A (en) *	2002-07-25	2007-07-04	Stephan Cherkez	Process for the preparation of stable amorphous calcium pseudomonate
US20040220153A1 (en) *	2002-09-24	2004-11-04	Jost-Price Edward Roydon	Methods and reagents for the treatment of diseases and disorders associated with increased levels of proinflammatory cytokines
MY162179A (en) *	2004-04-01	2017-05-31	Elan Pharm Inc	Steroid sparing agents and methods of using same
JP2006117569A (ja) *	2004-10-20	2006-05-11	Juntendo	ステロイド依存性あるいはステロイド抵抗性潰瘍性大腸炎治療薬
FR2884422B1 (fr) *	2005-04-18	2008-04-11	Roquette Freres	Composition anti-inflammatoire de l'intestin comprenant des maltodextrines branchees
US20080081067A1 (en) *	2006-10-03	2008-04-03	Gupta Manishkumar	Sustained release pharmaceutical compositions of venlafaxine and process for preparation thereof
WO2010043721A1 (en)	2008-10-17	2010-04-22	Oryzon Genomics, S.A.	Oxidase inhibitors and their use
US8993808B2 (en)	2009-01-21	2015-03-31	Oryzon Genomics, S.A.	Phenylcyclopropylamine derivatives and their medical use
US8859555B2 (en)	2009-09-25	2014-10-14	Oryzon Genomics S.A.	Lysine Specific Demethylase-1 inhibitors and their use
EP2486002B1 (de)	2009-10-09	2019-03-27	Oryzon Genomics, S.A.	Substituierte heteroaryl- und arylcyclopropylaminacetamide und ihre verwendung
WO2011106574A2 (en)	2010-02-24	2011-09-01	Oryzon Genomics, S.A.	Inhibitors for antiviral use
WO2011106106A2 (en)	2010-02-24	2011-09-01	Oryzon Genomics, S.A.	Lysine demethylase inhibitors for diseases and disorders associated with hepadnaviridae
WO2011116168A1 (en) *	2010-03-17	2011-09-22	Isp Investments Inc.	Biocide power formulation
CA2796726C (en)	2010-04-19	2021-02-16	Oryzon Genomics S.A.	Lysine specific demethylase-1 inhibitors and their use
BR112013002164B1 (pt)	2010-07-29	2021-11-09	Oryzon Genomics S.A.	Inibidores de desmetilase à base de arilciclopropilamina de lsd1, seus usos, e composição farmacêutica
US9006449B2 (en)	2010-07-29	2015-04-14	Oryzon Genomics, S.A.	Cyclopropylamine derivatives useful as LSD1 inhibitors
US9061966B2 (en)	2010-10-08	2015-06-23	Oryzon Genomics S.A.	Cyclopropylamine inhibitors of oxidases
WO2012072713A2 (en)	2010-11-30	2012-06-07	Oryzon Genomics, S.A.	Lysine demethylase inhibitors for diseases and disorders associated with flaviviridae
EP2712315B1 (de)	2011-02-08	2021-11-24	Oryzon Genomics, S.A.	Lysindemethylase-hemmer für myeloproliferative erkrankungen
US20140329833A1 (en) *	2011-05-19	2014-11-06	Oryzon Genomics, S.A	Lysine demethylase inhibitors for inflammatory diseases or conditions
LT2543357T (lt) *	2011-07-07	2018-06-11	Holy Stone Healthcare Co.,Ltd.	Kompozicija, skirta panaudoti su uždegimu susijusių susirgimų gydymui arba prevencijai
JP6046154B2 (ja)	2011-10-20	2016-12-14	オリソンヘノミクスエセ．アー．	Ｌｓｄ１阻害剤としての（ヘテロ）アリールシクロプロピルアミン化合物
EP2768805B1 (de)	2011-10-20	2020-03-25	Oryzon Genomics, S.A.	(hetero)aryl cyclopropylamin verbindungen als lsd1 hemmer
JPWO2013183407A1 (ja) *	2012-06-05	2016-01-28	祐徳薬品工業株式会社	ミルタザピン含有経皮吸収型貼付製剤
GB201211982D0 (en) *	2012-07-05	2012-08-22	Isis Innovation	Biomarker
CN104017102B (zh) *	2014-06-19	2016-02-24	深圳市海普瑞药业股份有限公司	乙醇沉淀法从肝素副产物制备舒洛地特原料的方法
US9668991B1 (en)	2015-12-09	2017-06-06	International Business Machines Corporation	SCFA colonic composition
CN108354943A (zh) *	2018-02-13	2018-08-03	南方医科大学南方医院	新生霉素用于制备抑制trpv1表达和转运功能的药物的用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2426586A1 (de) *	1973-06-14	1975-01-09	Opocrin Srl	Verfahren zur herstellung von glukuronil-glukosamin-glykan-sulfaten mit antilipaemischer wirkung
IT1274351B (it) *	1994-10-06	1997-07-17	Alfa Wassermann Spa	Uso di alcuni glicosaminoglicani nella dialisi peritoneale.
GB0003048D0 (en) *	2000-02-11	2000-03-29	Dealler Stephen F	The therapeutic use of polysulphonated polyglycosides or other polyanionic compounds in autism

2002
- 2002-05-16 US US10/147,681 patent/US20030008844A1/en not_active Abandoned
- 2002-05-19 AT AT02733192T patent/ATE333885T1/de not_active IP Right Cessation
- 2002-05-19 MX MXPA03010493A patent/MXPA03010493A/es active IP Right Grant
- 2002-05-19 WO PCT/IL2002/000384 patent/WO2003002129A1/en not_active Ceased
- 2002-05-19 AU AU2002304265A patent/AU2002304265B2/en not_active Expired - Fee Related
- 2002-05-19 DK DK02733192T patent/DK1392329T3/da active
- 2002-05-19 DE DE60213404T patent/DE60213404T2/de not_active Expired - Fee Related
- 2002-05-19 JP JP2003508368A patent/JP2004534087A/ja active Pending
- 2002-05-19 IL IL15890302A patent/IL158903A0/xx unknown
- 2002-05-19 EP EP02733192A patent/EP1392329B1/de not_active Expired - Lifetime
- 2002-05-19 NZ NZ530020A patent/NZ530020A/en unknown
- 2002-05-19 CA CA002447280A patent/CA2447280A1/en not_active Abandoned

Also Published As

Publication number	Publication date
DK1392329T3 (da)	2006-11-27
JP2004534087A (ja)	2004-11-11
MXPA03010493A (es)	2005-06-06
EP1392329B1 (de)	2006-07-26
US20030008844A1 (en)	2003-01-09
DE60213404D1 (de)	2006-09-07
NZ530020A (en)	2005-08-26
WO2003002129B1 (en)	2003-08-14
IL158903A0 (en)	2004-05-12
AU2002304265B2 (en)	2008-04-10
CA2447280A1 (en)	2003-01-09
WO2003002129A1 (en)	2003-01-09
EP1392329A1 (de)	2004-03-03
DE60213404T2 (de)	2007-08-30

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Legal Events

Date	Code	Title	Description
2007-01-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties