ATE334980T1 - Verfahren zur herstellung von 2-methyl piperazine derivaten. - Google Patents

Verfahren zur herstellung von 2-methyl piperazine derivaten.

Info

Publication number
ATE334980T1
ATE334980T1 AT03736405T AT03736405T ATE334980T1 AT E334980 T1 ATE334980 T1 AT E334980T1 AT 03736405 T AT03736405 T AT 03736405T AT 03736405 T AT03736405 T AT 03736405T AT E334980 T1 ATE334980 T1 AT E334980T1
Authority
AT
Austria
Prior art keywords
producing
methyl piperazine
piperazine derivatives
relates
present
Prior art date
Application number
AT03736405T
Other languages
English (en)
Inventor
Magnus Cernerud
Helena Lundstroem
Claes Loefstroem
Margit Pelcman
Tom Di Fleck
Alexander Paptchikhine
Emma Andersson
Alf Nygren
Original Assignee
Biovitrum Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE0201881A external-priority patent/SE0201881D0/xx
Priority claimed from SE0202041A external-priority patent/SE0202041D0/xx
Priority claimed from SE0202516A external-priority patent/SE0202516D0/xx
Application filed by Biovitrum Ab filed Critical Biovitrum Ab
Application granted granted Critical
Publication of ATE334980T1 publication Critical patent/ATE334980T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Luminescent Compositions (AREA)
  • Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
  • Pyridine Compounds (AREA)
AT03736405T 2002-06-19 2003-06-18 Verfahren zur herstellung von 2-methyl piperazine derivaten. ATE334980T1 (de)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
SE0201881A SE0201881D0 (sv) 2002-06-19 2002-06-19 Novel compounds, their use, and preparation
US39065602P 2002-06-21 2002-06-21
SE0202041A SE0202041D0 (sv) 2002-06-28 2002-06-28 Novel process
US40611902P 2002-08-26 2002-08-26
SE0202516A SE0202516D0 (sv) 2002-08-26 2002-08-26 Novel compounds, their use, and preparation
US41670102P 2002-10-07 2002-10-07

Publications (1)

Publication Number Publication Date
ATE334980T1 true ATE334980T1 (de) 2006-08-15

Family

ID=30004077

Family Applications (2)

Application Number Title Priority Date Filing Date
AT03736405T ATE334980T1 (de) 2002-06-19 2003-06-18 Verfahren zur herstellung von 2-methyl piperazine derivaten.
AT05023471T ATE398119T1 (de) 2002-06-19 2003-06-18 Piperazinylpyrazine als modulatoren des serotonin 5-ht2c rezeptors

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT05023471T ATE398119T1 (de) 2002-06-19 2003-06-18 Piperazinylpyrazine als modulatoren des serotonin 5-ht2c rezeptors

Country Status (16)

Country Link
EP (2) EP1529043B1 (de)
JP (4) JP4592417B2 (de)
CN (1) CN100334082C (de)
AT (2) ATE334980T1 (de)
AU (1) AU2003237746B8 (de)
CA (1) CA2485532C (de)
CY (1) CY1106225T1 (de)
DE (2) DE60321606D1 (de)
DK (2) DK1529043T3 (de)
ES (2) ES2307102T3 (de)
HK (1) HK1080079B (de)
NO (1) NO20050279D0 (de)
NZ (1) NZ536663A (de)
PT (2) PT1645558E (de)
SI (2) SI1645558T1 (de)
WO (1) WO2004000829A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5173190B2 (ja) 2004-08-25 2013-03-27 武田薬品工業株式会社 腹圧性尿失禁の予防・治療剤及びそのスクリーニング方法
JP5528699B2 (ja) 2006-05-16 2014-06-25 武田薬品工業株式会社 縮合複素環化合物およびその用途
KR101536021B1 (ko) 2007-10-16 2015-07-10 다이이찌 산쿄 가부시키가이샤 피리미딜 인돌린 화합물
JP5520051B2 (ja) 2007-11-15 2014-06-11 武田薬品工業株式会社 縮合ピリジン誘導体およびその用途
TWI542592B (zh) 2009-06-15 2016-07-21 武田藥品工業股份有限公司 吡並氮雜氧雜環庚烯衍生物
WO2011071136A1 (ja) 2009-12-11 2011-06-16 アステラス製薬株式会社 線維筋痛症治療剤
GB201304811D0 (en) * 2013-03-15 2013-05-01 Proximagen Ltd Novel treatment for hypertension
WO2019131902A1 (ja) 2017-12-27 2019-07-04 武田薬品工業株式会社 腹圧性尿失禁および便失禁の治療薬

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06306075A (ja) * 1993-04-23 1994-11-01 Sanwa Kagaku Kenkyusho Co Ltd エトキシベンズアミド誘導体
CA2374898C (en) * 1999-05-21 2009-12-08 Biovitrum Ab Pyrazinyl-piperazine compounds, their use and preparation
AR032318A1 (es) * 2000-04-13 2003-11-05 Pharmacia Corp Compuesto derivado halogenado del acido 2-amino-5,6 heptenoico; composicion farmaceutica que lo comprende y su uso en la fabricacion de un medicamento util como inhibidor de la oxido nitrico sintetasa
JP4204315B2 (ja) * 2000-11-20 2009-01-07 ビオヴィトルム・アクチボラゲット（プブリクト） セロトニン５−ｈｔ２レセプターのアンタゴニストとしてのピペラジニルピラジン化合物

Also Published As

Publication number Publication date
DE60321606D1 (de) 2008-07-24
AU2003237746B2 (en) 2009-12-17
CN100334082C (zh) 2007-08-29
EP1645558A1 (de) 2006-04-12
ES2307102T3 (es) 2008-11-16
DK1645558T3 (da) 2008-10-06
SI1645558T1 (sl) 2008-10-31
AU2003237746B8 (en) 2010-01-28
JP2013116906A (ja) 2013-06-13
JP5378241B2 (ja) 2013-12-25
CY1106225T1 (el) 2011-06-08
EP1529043A1 (de) 2005-05-11
DE60307286D1 (de) 2006-09-14
PT1645558E (pt) 2008-07-30
WO2004000829A1 (en) 2003-12-31
DK1529043T3 (da) 2006-12-04
ES2270051T3 (es) 2007-04-01
EP1529043B1 (de) 2006-08-02
JP2013227336A (ja) 2013-11-07
ATE398119T1 (de) 2008-07-15
SI1529043T1 (sl) 2006-12-31
CN1662523A (zh) 2005-08-31
NZ536663A (en) 2007-05-31
CA2485532C (en) 2012-03-06
JP4592417B2 (ja) 2010-12-01
NO20050279D0 (no) 2005-01-18
JP2010120949A (ja) 2010-06-03
JP2005537316A (ja) 2005-12-08
CA2485532A1 (en) 2003-12-31
HK1080079A1 (zh) 2006-04-21
DE60307286T2 (de) 2007-10-25
AU2003237746A1 (en) 2004-01-06
EP1645558B1 (de) 2008-06-11
PT1529043E (pt) 2006-12-29
HK1080079B (zh) 2008-03-14

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