ATE335724T1 - Antimykotische enediyne - Google Patents

Antimykotische enediyne

Info

Publication number
ATE335724T1
ATE335724T1 AT00970605T AT00970605T ATE335724T1 AT E335724 T1 ATE335724 T1 AT E335724T1 AT 00970605 T AT00970605 T AT 00970605T AT 00970605 T AT00970605 T AT 00970605T AT E335724 T1 ATE335724 T1 AT E335724T1
Authority
AT
Austria
Prior art keywords
enediyne
antifungal
enediynes
inclusive
hydroxyl group
Prior art date
Application number
AT00970605T
Other languages
English (en)
Inventor
Baoliang Cui
James Bruce Mcalpine
Maureen Kelly Talbot
Shu-Wei Yang
Original Assignee
Phytera Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phytera Inc filed Critical Phytera Inc
Application granted granted Critical
Publication of ATE335724T1 publication Critical patent/ATE335724T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyrrole Compounds (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT00970605T 1999-10-07 2000-10-05 Antimykotische enediyne ATE335724T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US15809999P 1999-10-07 1999-10-07

Publications (1)

Publication Number Publication Date
ATE335724T1 true ATE335724T1 (de) 2006-09-15

Family

ID=22566685

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00970605T ATE335724T1 (de) 1999-10-07 2000-10-05 Antimykotische enediyne

Country Status (10)

Country Link
US (1) US6541506B1 (de)
EP (1) EP1224168B1 (de)
JP (1) JP4865973B2 (de)
AT (1) ATE335724T1 (de)
AU (1) AU7995800A (de)
CA (1) CA2386514C (de)
DE (1) DE60029982T2 (de)
DK (1) DK1224168T3 (de)
ES (1) ES2269192T3 (de)
WO (1) WO2001025197A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030175678A1 (en) * 2001-01-24 2003-09-18 Bowen Benjamin A. Methods for identifying genes regulating desired cell phenotypes
US20050037039A1 (en) * 2003-08-12 2005-02-17 Yarbrough William M. Composition for treatment of tinea pedis and method of use
JP5132069B2 (ja) * 2006-03-31 2013-01-30 三井化学アグロ株式会社 ３−（ジヒドロ（又はテトラヒドロ）イソキノリン−１−イル）キノリン化合物を含む医薬用抗真菌剤
WO2011134538A1 (en) 2010-04-30 2011-11-03 Evolva Ltd Diyne compositions
KR20120079054A (ko) 2009-07-10 2012-07-11 에볼바 아게 디인 조성물
WO2023001905A1 (en) 2021-07-20 2023-01-26 Selmod Gmbh Novel antifungal compounds

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1453843A (fr) * 1965-03-18 1966-07-22 Pechiney Saint Gobain Composés nouveaux à action parasiticide
US3919260A (en) * 1973-12-03 1975-11-11 Ceskoslovenska Akademie Ved 9-(2-Tetrahydrofuryl)-2-nonenoic acid and 9-(2-tetrahydrofuryl)-2,4-nonadienoic acid and esters
US4958037A (en) * 1985-07-29 1990-09-18 American Cyanamid Company Precursors and synthesis of methyl-9-oxo-11α, 16-dihydroxy-16-vinyl-5-cis-13-trans-prostadienoates
EP0213313A3 (de) * 1985-07-29 1988-09-14 American Cyanamid Company Vorläufer und Synthese von 9-oxo-11-alpha-16-dihydroxy-16-vinyl-5-cis-13-transmethylprostadienoate
US4923884A (en) 1986-12-24 1990-05-08 Allergan, Inc. Ethynylheteroaromatic-acids having retinoic acid-like activity
NZ222968A (en) * 1986-12-24 1990-05-28 Allergan Inc Ethynylheteroaromatic derivatives and medicaments
JPH03170448A (ja) * 1989-11-29 1991-07-24 Mitsubishi Kasei Corp 鎖状テルペン系化合物
US5399724A (en) * 1989-11-29 1995-03-21 Mitsubishi Kasei Corporation Acyclic terpene compound

Also Published As

Publication number Publication date
EP1224168B1 (de) 2006-08-09
WO2001025197A1 (en) 2001-04-12
CA2386514A1 (en) 2001-04-12
JP2003511366A (ja) 2003-03-25
ES2269192T3 (es) 2007-04-01
JP4865973B2 (ja) 2012-02-01
AU7995800A (en) 2001-05-10
EP1224168A4 (de) 2003-05-02
EP1224168A1 (de) 2002-07-24
DE60029982D1 (de) 2006-09-21
DK1224168T3 (da) 2006-12-11
DE60029982T2 (de) 2007-03-15
US6541506B1 (en) 2003-04-01
CA2386514C (en) 2011-09-27

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