ATE336501T1 - Chi-conotoxinpeptide als inhibitoren neuronaler amintransporter - Google Patents

Chi-conotoxinpeptide als inhibitoren neuronaler amintransporter

Info

Publication number: ATE336501T1
Authority: AT; Austria
Prior art keywords: chi; inhibitors; conotoxin peptides; amine transporters; peptides
Prior art date: 1998-10-02

Application number

AT99952156T

Other languages

English (en)

Inventor

Richard James Lewis

Paul Francis Alewood

Iain Andrew Sharpe

Original Assignee

Xenome Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-10-02

Filing date

1999-10-01

Publication date

2006-09-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=3810492&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE336501(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1999-10-01 Application filed by Xenome Ltd filed Critical Xenome Ltd

2006-09-15 Application granted granted Critical

2006-09-15 Publication of ATE336501T1 publication Critical patent/ATE336501T1/de

Links

108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
150000001412 amines Chemical class 0.000 title abstract 2
230000001537 neural effect Effects 0.000 title abstract 2
239000003112 inhibitor Substances 0.000 title 1
102000039446 nucleic acids Human genes 0.000 abstract 1
108020004707 nucleic acids Proteins 0.000 abstract 1
150000007523 nucleic acids Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Cardiology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biochemistry (AREA)
Pain & Pain Management (AREA)
Heart & Thoracic Surgery (AREA)
Zoology (AREA)
Urology & Nephrology (AREA)
Psychiatry (AREA)
Gastroenterology & Hepatology (AREA)
Addiction (AREA)
Rheumatology (AREA)
Tropical Medicine & Parasitology (AREA)
Toxicology (AREA)
Hospice & Palliative Care (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

AT99952156T 1998-10-02 1999-10-01 Chi-conotoxinpeptide als inhibitoren neuronaler amintransporter ATE336501T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
AUPP6274A AUPP627498A0 (en)	1998-10-02	1998-10-02	Novel peptides - i

Publications (1)

Publication Number	Publication Date
ATE336501T1 true ATE336501T1 (de)	2006-09-15

Family

ID=3810492

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99952156T ATE336501T1 (de)	1998-10-02	1999-10-01	Chi-conotoxinpeptide als inhibitoren neuronaler amintransporter

Country Status (13)

Country	Link
US (4)	US6794361B1 (de)
EP (1)	EP1117682B1 (de)
JP (2)	JP4447783B2 (de)
AT (1)	ATE336501T1 (de)
AU (1)	AUPP627498A0 (de)
CA (1)	CA2344765A1 (de)
CY (1)	CY1110381T1 (de)
DE (1)	DE69932834T2 (de)
DK (1)	DK1117682T3 (de)
ES (1)	ES2268885T3 (de)
NZ (1)	NZ510813A (de)
PT (1)	PT1117682E (de)
WO (1)	WO2000020444A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AUPP627498A0 (en) *	1998-10-02	1998-10-22	University Of Queensland, The	Novel peptides - i
US6767896B1 (en)	1999-01-29	2004-07-27	Cognetix, Inc.	Conotoxin peptides
WO2002060923A2 (en) *	2001-01-29	2002-08-08	Cognetix, Inc.	B-superfamily conotoxins
ES2383358T3 (es) *	2002-12-02	2012-06-20	Xenome Ltd	Péptidos de chi-conotoxina que tienen un ácido piroglutámico N-terminal
US7507717B2 (en) *	2002-12-02	2009-03-24	Xenome Ltd.	Type II chi-conotoxin peptides (noradrenaline transporter inhibitors)
WO2006028420A1 (en) *	2004-09-09	2006-03-16	National University Of Singapore	Conformational switches in toxin folding and uses thereof
US8188048B2 (en)	2006-06-23	2012-05-29	Xenome Limited	Combination therapy
CN103372198B (zh) *	2012-04-12	2016-04-06	同济大学	用于抑制病毒的多肽抑制剂
WO2016191200A1 (en)	2015-05-22	2016-12-01	Clemson University	Conotoxin peptides for use in biofouling deterrence
MX2018002183A (es)	2015-08-27	2018-05-28	Harvard College	Composiciones y metodos para tratamiento del dolor.

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5051403A (en)	1989-11-22	1991-09-24	Neurex Corporation	Method of treating ischemia-related neuronal damage
ZA921292B (en)	1991-02-25	1993-08-23	Lilly Co Eli	Treatment of lower urinary tract disorders.
EP0625162B1 (de)	1991-12-30	1998-05-13	Neurex Corporation	Methoden zur erzeugung von analgesie und zur verstärkung von opiat-analgesie
ATE215832T1 (de) *	1994-05-09	2002-04-15	William J Binder	Botulinumtoxin zur reduktion von migraine - kopfschmerzen
ATE218359T1 (de)	1994-11-03	2002-06-15	Novartis Erfind Verwalt Gmbh	Neue zubereitungsformen des cyclosporins zur oralen applikation mit einfacher zusammensetzung und hoher bioverfügbarkeit und verfahren zu deren herstellung
WO1996040064A1 (en)	1995-06-07	1996-12-19	Nexstar Pharmaceuticals, Inc.	Liposomal cyclosporin formulations as agents for immunosuppression and multiple drug resistant indications
DE69627153T2 (de)	1995-06-27	2003-12-04	Elan Pharmaceuticals, Inc.(N.D.Ges.D.Staates Delaware)	Zusammensetzungen zur erzielung von analgesie und zur hemmung der progression neuropathischer schmerzerkrankungen
ZA971525B (en)	1996-02-22	1997-10-21	Neurosearch As	Tropane derivatives, their preparation and use.
GB9614902D0 (en)	1996-07-16	1996-09-04	Rhodes John	Sustained release composition
CZ288739B6 (cs)	1996-08-01	2001-08-15	Galena, A. S.	Cyklosporin obsahující léčivé přípravky
WO1998022126A1 (en)	1996-11-18	1998-05-28	University Of Utah Research Foundation	USE OF CONOTOXIN PEPTIDES ImI AND MII AS CARDIOVASCULAR AGENTS
ATE248147T1 (de)	1997-05-14	2003-09-15	Neurosearch As	Piperidine derivate als inhibitoren der neurotransmitter-wiederaufbaunahme
AUPP627498A0 (en) *	1998-10-02	1998-10-22	University Of Queensland, The	Novel peptides - i
AU3473800A (en)	1999-01-29	2000-08-18	University Of Utah Research Foundation	Conotoxin peptides
US7507717B2 (en) *	2002-12-02	2009-03-24	Xenome Ltd.	Type II chi-conotoxin peptides (noradrenaline transporter inhibitors)
ES2383358T3 (es) *	2002-12-02	2012-06-20	Xenome Ltd	Péptidos de chi-conotoxina que tienen un ácido piroglutámico N-terminal

1998
- 1998-10-02 AU AUPP6274A patent/AUPP627498A0/en not_active Abandoned
1999
- 1999-10-01 AT AT99952156T patent/ATE336501T1/de active
- 1999-10-01 US US09/787,986 patent/US6794361B1/en not_active Expired - Fee Related
- 1999-10-01 DE DE69932834T patent/DE69932834T2/de not_active Expired - Lifetime
- 1999-10-01 NZ NZ510813A patent/NZ510813A/en not_active IP Right Cessation
- 1999-10-01 WO PCT/AU1999/000844 patent/WO2000020444A1/en not_active Ceased
- 1999-10-01 JP JP2000574555A patent/JP4447783B2/ja not_active Expired - Fee Related
- 1999-10-01 ES ES99952156T patent/ES2268885T3/es not_active Expired - Lifetime
- 1999-10-01 EP EP99952156A patent/EP1117682B1/de not_active Expired - Lifetime
- 1999-10-01 CA CA002344765A patent/CA2344765A1/en not_active Abandoned
- 1999-10-01 PT PT99952156T patent/PT1117682E/pt unknown
- 1999-10-01 DK DK99952156T patent/DK1117682T3/da active
2004
- 2004-08-13 US US10/918,096 patent/US7326682B2/en not_active Expired - Fee Related
2006
- 2006-11-09 CY CY20061101621T patent/CY1110381T1/el unknown
2007
- 2007-11-02 US US11/934,723 patent/US7994128B2/en not_active Expired - Fee Related
2009
- 2009-10-26 JP JP2009245436A patent/JP2010046088A/ja active Pending
2011
- 2011-05-25 US US13/115,711 patent/US20120277166A1/en not_active Abandoned

Also Published As

Publication number	Publication date
CY1110381T1 (el)	2015-04-29
US7994128B2 (en)	2011-08-09
ES2268885T3 (es)	2007-03-16
EP1117682A4 (de)	2001-12-12
CA2344765A1 (en)	2000-04-13
JP4447783B2 (ja)	2010-04-07
DK1117682T3 (da)	2006-12-27
JP2010046088A (ja)	2010-03-04
DE69932834T2 (de)	2007-08-23
AUPP627498A0 (en)	1998-10-22
DE69932834D1 (de)	2006-09-28
NZ510813A (en)	2003-08-29
US6794361B1 (en)	2004-09-21
EP1117682A1 (de)	2001-07-25
US20090275498A1 (en)	2009-11-05
EP1117682B1 (de)	2006-08-16
US7326682B2 (en)	2008-02-05
WO2000020444A1 (en)	2000-04-13
US20050054827A1 (en)	2005-03-10
PT1117682E (pt)	2006-12-29
US20120277166A1 (en)	2012-11-01
JP2002526098A (ja)	2002-08-20

Legal Events

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2007-02-15

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