ATE336501T1 - Chi-conotoxinpeptide als inhibitoren neuronaler amintransporter - Google Patents

Chi-conotoxinpeptide als inhibitoren neuronaler amintransporter

Info

Publication number
ATE336501T1
ATE336501T1 AT99952156T AT99952156T ATE336501T1 AT E336501 T1 ATE336501 T1 AT E336501T1 AT 99952156 T AT99952156 T AT 99952156T AT 99952156 T AT99952156 T AT 99952156T AT E336501 T1 ATE336501 T1 AT E336501T1
Authority
AT
Austria
Prior art keywords
chi
inhibitors
conotoxin peptides
amine transporters
peptides
Prior art date
Application number
AT99952156T
Other languages
English (en)
Inventor
Richard James Lewis
Paul Francis Alewood
Iain Andrew Sharpe
Original Assignee
Xenome Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=3810492&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE336501(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Xenome Ltd filed Critical Xenome Ltd
Application granted granted Critical
Publication of ATE336501T1 publication Critical patent/ATE336501T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34Tobacco-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Addiction (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Psychiatry (AREA)
  • Zoology (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT99952156T 1998-10-02 1999-10-01 Chi-conotoxinpeptide als inhibitoren neuronaler amintransporter ATE336501T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AUPP6274A AUPP627498A0 (en) 1998-10-02 1998-10-02 Novel peptides - i

Publications (1)

Publication Number Publication Date
ATE336501T1 true ATE336501T1 (de) 2006-09-15

Family

ID=3810492

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99952156T ATE336501T1 (de) 1998-10-02 1999-10-01 Chi-conotoxinpeptide als inhibitoren neuronaler amintransporter

Country Status (13)

Country Link
US (4) US6794361B1 (de)
EP (1) EP1117682B1 (de)
JP (2) JP4447783B2 (de)
AT (1) ATE336501T1 (de)
AU (1) AUPP627498A0 (de)
CA (1) CA2344765A1 (de)
CY (1) CY1110381T1 (de)
DE (1) DE69932834T2 (de)
DK (1) DK1117682T3 (de)
ES (1) ES2268885T3 (de)
NZ (1) NZ510813A (de)
PT (1) PT1117682E (de)
WO (1) WO2000020444A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPP627498A0 (en) * 1998-10-02 1998-10-22 University Of Queensland, The Novel peptides - i
US6767896B1 (en) 1999-01-29 2004-07-27 Cognetix, Inc. Conotoxin peptides
US20030170222A1 (en) 2001-01-29 2003-09-11 University Of Utah Research Foundation Beta-superfamily conotoxins
US7507717B2 (en) * 2002-12-02 2009-03-24 Xenome Ltd. Type II chi-conotoxin peptides (noradrenaline transporter inhibitors)
WO2004050690A1 (en) * 2002-12-02 2004-06-17 Xenome Ltd NOVEL χ-CONOTOXIN PEPTIDES (-I)
JP2008512452A (ja) * 2004-09-09 2008-04-24 ナショナル ユニヴァーシティ オブ シンガポール トキシン折り畳みにおける配座スイッチおよびその使用
US8188048B2 (en) 2006-06-23 2012-05-29 Xenome Limited Combination therapy
CN103372198B (zh) * 2012-04-12 2016-04-06 同济大学 用于抑制病毒的多肽抑制剂
WO2016191200A1 (en) 2015-05-22 2016-12-01 Clemson University Conotoxin peptides for use in biofouling deterrence
US11753633B2 (en) 2015-08-27 2023-09-12 President And Fellows Of Harvard College Compositions and methods for treatment of pain

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5051403A (en) 1989-11-22 1991-09-24 Neurex Corporation Method of treating ischemia-related neuronal damage
PH30083A (en) 1991-02-25 1996-12-27 Lilly Co Eli Treatment of lower urinary tract disorders
ATE165977T1 (de) * 1991-12-30 1998-05-15 Neurex Corp Methoden zur erzeugung von analgesie und zur verstärkung von opiat-analgesie
EP1086702B1 (de) * 1994-05-09 2005-04-13 BINDER, William J. Präsynaptische Neurotoxine gegen Migränekopfschmerzen
ES2177652T3 (es) 1994-11-03 2002-12-16 Novartis Ag Nuevas formas de preparacion de ciclosporina para la aplicacion oral con composicion simple y alta biodisponibilidad, y procedimiento para su obtencion.
AU6047996A (en) 1995-06-07 1996-12-30 Nexstar Pharmaceuticals, Inc. Liposomal cyclosporin formulations as agents for immunosuppr ession and multiple drug resistant indications
ES2194998T3 (es) 1995-06-27 2003-12-01 Elan Pharm Inc Composiciones y formulaciones para producir analgesia y para inhibir la progresion de trastornos de dolor neuropatico.
BR9707636A (pt) 1996-02-22 1999-07-27 Neurosearch As Composto composição farmacêutica uso de um composto e processos para preparar composto e para tratar um distúrbio ou doença de um organismo animal vivo
GB9614902D0 (en) 1996-07-16 1996-09-04 Rhodes John Sustained release composition
CZ288739B6 (cs) 1996-08-01 2001-08-15 Galena, A. S. Cyklosporin obsahující léčivé přípravky
AU735724B2 (en) 1996-11-18 2001-07-12 University Of Utah Research Foundation Use of conotoxin peptides ImI and MII as cardiovascular agents
ATE248147T1 (de) 1997-05-14 2003-09-15 Neurosearch As Piperidine derivate als inhibitoren der neurotransmitter-wiederaufbaunahme
AUPP627498A0 (en) * 1998-10-02 1998-10-22 University Of Queensland, The Novel peptides - i
WO2000044769A1 (en) 1999-01-29 2000-08-03 University Of Utah Research Foundation Conotoxin peptides
US7507717B2 (en) * 2002-12-02 2009-03-24 Xenome Ltd. Type II chi-conotoxin peptides (noradrenaline transporter inhibitors)
WO2004050690A1 (en) * 2002-12-02 2004-06-17 Xenome Ltd NOVEL χ-CONOTOXIN PEPTIDES (-I)

Also Published As

Publication number Publication date
DE69932834D1 (de) 2006-09-28
JP2010046088A (ja) 2010-03-04
DK1117682T3 (da) 2006-12-27
NZ510813A (en) 2003-08-29
CY1110381T1 (el) 2015-04-29
US6794361B1 (en) 2004-09-21
EP1117682A1 (de) 2001-07-25
CA2344765A1 (en) 2000-04-13
US20090275498A1 (en) 2009-11-05
ES2268885T3 (es) 2007-03-16
PT1117682E (pt) 2006-12-29
AUPP627498A0 (en) 1998-10-22
WO2000020444A1 (en) 2000-04-13
US7994128B2 (en) 2011-08-09
EP1117682A4 (de) 2001-12-12
US20120277166A1 (en) 2012-11-01
JP2002526098A (ja) 2002-08-20
US7326682B2 (en) 2008-02-05
US20050054827A1 (en) 2005-03-10
DE69932834T2 (de) 2007-08-23
JP4447783B2 (ja) 2010-04-07
EP1117682B1 (de) 2006-08-16

Similar Documents

Publication Publication Date Title
ATE368688T1 (de) Peptide, deren herstellung und verwendung zur bindung von immunglobulinen
DE69932834D1 (de) Chi-Conotoxinpeptide als Inhibitoren neuronaler Amintransporter
DE69931482D1 (de) Isolierte peptide die aminosäuresequenzen von ny-eso-1 entsprechen und an mhc-klasse i und mhc klasse ii moleküle binden, und deren verwendungen
WO2002046407A3 (en) Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
DE60234843D1 (de) Modifizierte peptide und deren verwendung zur behandlung von autoimmunkrankheiten
NZ510812A (en) Novel peptides
WO2001081412A3 (en) Isolated human transporter proteins, nucleic acid molecules encoding the same, and uses thereof
WO2002046406A3 (en) Human transporter proteins, nucleic acid molecules encoding them,and uses thereof
WO2002022678A3 (en) Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
WO2002024910A3 (en) Isolated human transporter proteins, nucleic acid molecules encoding them, and uses thereof
WO2002057310A3 (en) Human transporter proteins, nucleic acid molecules encoding them, and uses thereof
WO2002046217A3 (en) Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
WO2002033086A3 (en) Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
WO2002020757A3 (en) Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
WO2002024748A3 (en) Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
WO2003070882A3 (en) Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and used thereof
WO2002081692A3 (en) Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
WO2002048364A3 (en) Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
WO2002048366A3 (en) Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
WO2002066642A3 (en) Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
WO2001088136A3 (en) Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
WO2002048365A3 (en) Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
WO2002053740A3 (en) Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
WO2001090360A3 (en) Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
WO2002081657A3 (en) Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1117682

Country of ref document: EP