ATE336501T1 - Chi-conotoxinpeptide als inhibitoren neuronaler amintransporter - Google Patents
Chi-conotoxinpeptide als inhibitoren neuronaler amintransporterInfo
- Publication number
- ATE336501T1 ATE336501T1 AT99952156T AT99952156T ATE336501T1 AT E336501 T1 ATE336501 T1 AT E336501T1 AT 99952156 T AT99952156 T AT 99952156T AT 99952156 T AT99952156 T AT 99952156T AT E336501 T1 ATE336501 T1 AT E336501T1
- Authority
- AT
- Austria
- Prior art keywords
- chi
- inhibitors
- conotoxin peptides
- amine transporters
- peptides
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 150000001412 amines Chemical class 0.000 title abstract 2
- 230000001537 neural effect Effects 0.000 title abstract 2
- 239000003112 inhibitor Substances 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Cardiology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Psychiatry (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Urology & Nephrology (AREA)
- Addiction (AREA)
- Toxicology (AREA)
- Hospice & Palliative Care (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AUPP6274A AUPP627498A0 (en) | 1998-10-02 | 1998-10-02 | Novel peptides - i |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE336501T1 true ATE336501T1 (de) | 2006-09-15 |
Family
ID=3810492
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99952156T ATE336501T1 (de) | 1998-10-02 | 1999-10-01 | Chi-conotoxinpeptide als inhibitoren neuronaler amintransporter |
Country Status (13)
| Country | Link |
|---|---|
| US (4) | US6794361B1 (de) |
| EP (1) | EP1117682B1 (de) |
| JP (2) | JP4447783B2 (de) |
| AT (1) | ATE336501T1 (de) |
| AU (1) | AUPP627498A0 (de) |
| CA (1) | CA2344765A1 (de) |
| CY (1) | CY1110381T1 (de) |
| DE (1) | DE69932834T2 (de) |
| DK (1) | DK1117682T3 (de) |
| ES (1) | ES2268885T3 (de) |
| NZ (1) | NZ510813A (de) |
| PT (1) | PT1117682E (de) |
| WO (1) | WO2000020444A1 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPP627498A0 (en) * | 1998-10-02 | 1998-10-22 | University Of Queensland, The | Novel peptides - i |
| US6767896B1 (en) | 1999-01-29 | 2004-07-27 | Cognetix, Inc. | Conotoxin peptides |
| WO2002060923A2 (en) * | 2001-01-29 | 2002-08-08 | Cognetix, Inc. | B-superfamily conotoxins |
| ATE547424T1 (de) * | 2002-12-02 | 2012-03-15 | Xenome Ltd | Chi-conotoxinpeptide mit einer n-terminalen pyroglutaminsäure |
| EP2412719A1 (de) | 2002-12-02 | 2012-02-01 | Xenome Ltd | Chi-Conotoxin-Peptide |
| EP1791857A4 (de) * | 2004-09-09 | 2009-04-08 | Univ Singapore | Konformationswechsel in der toxinfaltung und verwendungen dafür |
| US8188048B2 (en) | 2006-06-23 | 2012-05-29 | Xenome Limited | Combination therapy |
| CN103372198B (zh) * | 2012-04-12 | 2016-04-06 | 同济大学 | 用于抑制病毒的多肽抑制剂 |
| JP6731044B2 (ja) | 2015-05-22 | 2020-07-29 | クレムソン・ユニバーシティ・リサーチ・ファウンデーション | 生物付着の抑止において用いるためのコノトキシンペプチド |
| EA201890587A1 (ru) | 2015-08-27 | 2018-09-28 | Президент Энд Феллоуз Оф Гарвард Колледж | Композиции и способы для лечения боли |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5051403A (en) | 1989-11-22 | 1991-09-24 | Neurex Corporation | Method of treating ischemia-related neuronal damage |
| AU642582B2 (en) | 1991-02-25 | 1993-10-21 | Eli Lilly And Company | Treatment of lower urinary tract disorders |
| SG50624A1 (en) * | 1991-12-30 | 1998-07-20 | Neurex Corp | Methods of producing analgesia and enhancing opiate analgesia |
| EP1086702B1 (de) * | 1994-05-09 | 2005-04-13 | BINDER, William J. | Präsynaptische Neurotoxine gegen Migränekopfschmerzen |
| JP3833248B2 (ja) | 1994-11-03 | 2006-10-11 | ノバルティス・アクチエンゲゼルシャフト | 簡単な組成及び高い生物有効性を有する経口投与のためのシクロスポリンの新規処方物及びその製造法 |
| WO1996040064A1 (en) | 1995-06-07 | 1996-12-19 | Nexstar Pharmaceuticals, Inc. | Liposomal cyclosporin formulations as agents for immunosuppression and multiple drug resistant indications |
| DK0835126T3 (da) | 1995-06-27 | 2003-07-14 | Elan Pharm Inc | Sammensætninger og formuleringer til fremstilling af analgesimidler og til hamning af fremadskridende neuropatiske amertelidelser |
| BR9707636A (pt) | 1996-02-22 | 1999-07-27 | Neurosearch As | Composto composição farmacêutica uso de um composto e processos para preparar composto e para tratar um distúrbio ou doença de um organismo animal vivo |
| GB9614902D0 (en) | 1996-07-16 | 1996-09-04 | Rhodes John | Sustained release composition |
| CZ288739B6 (cs) | 1996-08-01 | 2001-08-15 | Galena, A. S. | Cyklosporin obsahující léčivé přípravky |
| WO1998022126A1 (en) | 1996-11-18 | 1998-05-28 | University Of Utah Research Foundation | USE OF CONOTOXIN PEPTIDES ImI AND MII AS CARDIOVASCULAR AGENTS |
| AU7206398A (en) | 1997-05-14 | 1998-12-08 | Neurosearch A/S | Piperidine derivatives as neurotransmitter re-uptake inhibitors |
| AUPP627498A0 (en) * | 1998-10-02 | 1998-10-22 | University Of Queensland, The | Novel peptides - i |
| WO2000044769A1 (en) | 1999-01-29 | 2000-08-03 | University Of Utah Research Foundation | Conotoxin peptides |
| EP2412719A1 (de) * | 2002-12-02 | 2012-02-01 | Xenome Ltd | Chi-Conotoxin-Peptide |
| ATE547424T1 (de) * | 2002-12-02 | 2012-03-15 | Xenome Ltd | Chi-conotoxinpeptide mit einer n-terminalen pyroglutaminsäure |
-
1998
- 1998-10-02 AU AUPP6274A patent/AUPP627498A0/en not_active Abandoned
-
1999
- 1999-10-01 JP JP2000574555A patent/JP4447783B2/ja not_active Expired - Fee Related
- 1999-10-01 AT AT99952156T patent/ATE336501T1/de active
- 1999-10-01 US US09/787,986 patent/US6794361B1/en not_active Expired - Fee Related
- 1999-10-01 DK DK99952156T patent/DK1117682T3/da active
- 1999-10-01 CA CA002344765A patent/CA2344765A1/en not_active Abandoned
- 1999-10-01 EP EP99952156A patent/EP1117682B1/de not_active Expired - Lifetime
- 1999-10-01 WO PCT/AU1999/000844 patent/WO2000020444A1/en not_active Ceased
- 1999-10-01 ES ES99952156T patent/ES2268885T3/es not_active Expired - Lifetime
- 1999-10-01 NZ NZ510813A patent/NZ510813A/en not_active IP Right Cessation
- 1999-10-01 DE DE69932834T patent/DE69932834T2/de not_active Expired - Lifetime
- 1999-10-01 PT PT99952156T patent/PT1117682E/pt unknown
-
2004
- 2004-08-13 US US10/918,096 patent/US7326682B2/en not_active Expired - Fee Related
-
2006
- 2006-11-09 CY CY20061101621T patent/CY1110381T1/el unknown
-
2007
- 2007-11-02 US US11/934,723 patent/US7994128B2/en not_active Expired - Fee Related
-
2009
- 2009-10-26 JP JP2009245436A patent/JP2010046088A/ja active Pending
-
2011
- 2011-05-25 US US13/115,711 patent/US20120277166A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE69932834T2 (de) | 2007-08-23 |
| US20050054827A1 (en) | 2005-03-10 |
| US6794361B1 (en) | 2004-09-21 |
| US7326682B2 (en) | 2008-02-05 |
| JP4447783B2 (ja) | 2010-04-07 |
| WO2000020444A1 (en) | 2000-04-13 |
| US20120277166A1 (en) | 2012-11-01 |
| EP1117682A1 (de) | 2001-07-25 |
| CA2344765A1 (en) | 2000-04-13 |
| AUPP627498A0 (en) | 1998-10-22 |
| US20090275498A1 (en) | 2009-11-05 |
| JP2010046088A (ja) | 2010-03-04 |
| ES2268885T3 (es) | 2007-03-16 |
| DE69932834D1 (de) | 2006-09-28 |
| DK1117682T3 (da) | 2006-12-27 |
| JP2002526098A (ja) | 2002-08-20 |
| EP1117682B1 (de) | 2006-08-16 |
| PT1117682E (pt) | 2006-12-29 |
| EP1117682A4 (de) | 2001-12-12 |
| NZ510813A (en) | 2003-08-29 |
| US7994128B2 (en) | 2011-08-09 |
| CY1110381T1 (el) | 2015-04-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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