ATE336501T1 - Chi-conotoxinpeptide als inhibitoren neuronaler amintransporter - Google Patents

Chi-conotoxinpeptide als inhibitoren neuronaler amintransporter

Info

Publication number
ATE336501T1
ATE336501T1 AT99952156T AT99952156T ATE336501T1 AT E336501 T1 ATE336501 T1 AT E336501T1 AT 99952156 T AT99952156 T AT 99952156T AT 99952156 T AT99952156 T AT 99952156T AT E336501 T1 ATE336501 T1 AT E336501T1
Authority
AT
Austria
Prior art keywords
chi
inhibitors
conotoxin peptides
amine transporters
peptides
Prior art date
Application number
AT99952156T
Other languages
English (en)
Inventor
Richard James Lewis
Paul Francis Alewood
Iain Andrew Sharpe
Original Assignee
Xenome Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=3810492&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE336501(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Xenome Ltd filed Critical Xenome Ltd
Application granted granted Critical
Publication of ATE336501T1 publication Critical patent/ATE336501T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34Tobacco-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Addiction (AREA)
  • Zoology (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT99952156T 1998-10-02 1999-10-01 Chi-conotoxinpeptide als inhibitoren neuronaler amintransporter ATE336501T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AUPP6274A AUPP627498A0 (en) 1998-10-02 1998-10-02 Novel peptides - i

Publications (1)

Publication Number Publication Date
ATE336501T1 true ATE336501T1 (de) 2006-09-15

Family

ID=3810492

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99952156T ATE336501T1 (de) 1998-10-02 1999-10-01 Chi-conotoxinpeptide als inhibitoren neuronaler amintransporter

Country Status (13)

Country Link
US (4) US6794361B1 (de)
EP (1) EP1117682B1 (de)
JP (2) JP4447783B2 (de)
AT (1) ATE336501T1 (de)
AU (1) AUPP627498A0 (de)
CA (1) CA2344765A1 (de)
CY (1) CY1110381T1 (de)
DE (1) DE69932834T2 (de)
DK (1) DK1117682T3 (de)
ES (1) ES2268885T3 (de)
NZ (1) NZ510813A (de)
PT (1) PT1117682E (de)
WO (1) WO2000020444A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPP627498A0 (en) * 1998-10-02 1998-10-22 University Of Queensland, The Novel peptides - i
US6767896B1 (en) 1999-01-29 2004-07-27 Cognetix, Inc. Conotoxin peptides
AU2002245340A1 (en) * 2001-01-29 2002-08-12 Cognetix, Inc. B-superfamily conotoxins
WO2004050690A1 (en) * 2002-12-02 2004-06-17 Xenome Ltd NOVEL χ-CONOTOXIN PEPTIDES (-I)
EP2412719A1 (de) 2002-12-02 2012-02-01 Xenome Ltd Chi-Conotoxin-Peptide
JP2008512452A (ja) * 2004-09-09 2008-04-24 ナショナル ユニヴァーシティ オブ シンガポール トキシン折り畳みにおける配座スイッチおよびその使用
US8188048B2 (en) 2006-06-23 2012-05-29 Xenome Limited Combination therapy
CN103372198B (zh) * 2012-04-12 2016-04-06 同济大学 用于抑制病毒的多肽抑制剂
WO2016191200A1 (en) 2015-05-22 2016-12-01 Clemson University Conotoxin peptides for use in biofouling deterrence
BR112018003782A2 (pt) 2015-08-27 2018-09-25 Ipsen Pharma Sas composições e métodos para o tratamento da dor

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5051403A (en) 1989-11-22 1991-09-24 Neurex Corporation Method of treating ischemia-related neuronal damage
CA2061665C (en) 1991-02-25 2002-04-16 Mark Mortensen Foreman Treatment of lower urinary tract disorders
WO1993013128A1 (en) * 1991-12-30 1993-07-08 Neurex Corporation Methods of producing analgesia and enhancing opiate analgesia
EP0758900B1 (de) * 1994-05-09 2002-04-10 BINDER, William J. Botulinumtoxin ZUR REDUKTION VON Migraine -KOPFSCHMERZEN
SK164796A3 (en) 1994-11-03 1997-06-04 Dresden Arzneimittel Novel cyclosporine preparation forms for oral administration of and process for producing them
AU6047996A (en) 1995-06-07 1996-12-30 Nexstar Pharmaceuticals, Inc. Liposomal cyclosporin formulations as agents for immunosuppr ession and multiple drug resistant indications
EP1336409B1 (de) 1995-06-27 2007-04-11 Eisai R&D Management Co., Ltd. Zusammensetzungen zur Erzielung von Analgesie und zur Hemmung der Progression neuropathischer Schmerzerkrankungen
JP3238414B2 (ja) 1996-02-22 2001-12-17 ニューロサーチ・アクティーゼルスカブ トロパン―誘導体、その製造方法及びその使用方法
GB9614902D0 (en) 1996-07-16 1996-09-04 Rhodes John Sustained release composition
CZ288739B6 (cs) 1996-08-01 2001-08-15 Galena, A. S. Cyklosporin obsahující léčivé přípravky
CA2271769A1 (en) * 1996-11-18 1998-05-28 University Of Utah Research Foundation Use of conotoxin peptides imi and mii as cardiovascular agents
WO1998051668A1 (en) 1997-05-14 1998-11-19 Neurosearch A/S Piperidine derivatives as neurotransmitter re-uptake inhibitors
AUPP627498A0 (en) * 1998-10-02 1998-10-22 University Of Queensland, The Novel peptides - i
AU3473800A (en) 1999-01-29 2000-08-18 University Of Utah Research Foundation Conotoxin peptides
WO2004050690A1 (en) * 2002-12-02 2004-06-17 Xenome Ltd NOVEL χ-CONOTOXIN PEPTIDES (-I)
EP2412719A1 (de) * 2002-12-02 2012-02-01 Xenome Ltd Chi-Conotoxin-Peptide

Also Published As

Publication number Publication date
US7326682B2 (en) 2008-02-05
WO2000020444A1 (en) 2000-04-13
DK1117682T3 (da) 2006-12-27
CY1110381T1 (el) 2015-04-29
EP1117682B1 (de) 2006-08-16
AUPP627498A0 (en) 1998-10-22
EP1117682A4 (de) 2001-12-12
EP1117682A1 (de) 2001-07-25
PT1117682E (pt) 2006-12-29
ES2268885T3 (es) 2007-03-16
US20050054827A1 (en) 2005-03-10
JP2002526098A (ja) 2002-08-20
US6794361B1 (en) 2004-09-21
JP2010046088A (ja) 2010-03-04
US20120277166A1 (en) 2012-11-01
US7994128B2 (en) 2011-08-09
DE69932834D1 (de) 2006-09-28
JP4447783B2 (ja) 2010-04-07
CA2344765A1 (en) 2000-04-13
US20090275498A1 (en) 2009-11-05
DE69932834T2 (de) 2007-08-23
NZ510813A (en) 2003-08-29

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