ATE336501T1 - Chi-conotoxinpeptide als inhibitoren neuronaler amintransporter - Google Patents

Chi-conotoxinpeptide als inhibitoren neuronaler amintransporter

Info

Publication number
ATE336501T1
ATE336501T1 AT99952156T AT99952156T ATE336501T1 AT E336501 T1 ATE336501 T1 AT E336501T1 AT 99952156 T AT99952156 T AT 99952156T AT 99952156 T AT99952156 T AT 99952156T AT E336501 T1 ATE336501 T1 AT E336501T1
Authority
AT
Austria
Prior art keywords
chi
inhibitors
conotoxin peptides
amine transporters
peptides
Prior art date
Application number
AT99952156T
Other languages
English (en)
Inventor
Richard James Lewis
Paul Francis Alewood
Iain Andrew Sharpe
Original Assignee
Xenome Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=3810492&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE336501(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Xenome Ltd filed Critical Xenome Ltd
Application granted granted Critical
Publication of ATE336501T1 publication Critical patent/ATE336501T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34Tobacco-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Urology & Nephrology (AREA)
  • Addiction (AREA)
  • Toxicology (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT99952156T 1998-10-02 1999-10-01 Chi-conotoxinpeptide als inhibitoren neuronaler amintransporter ATE336501T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AUPP6274A AUPP627498A0 (en) 1998-10-02 1998-10-02 Novel peptides - i

Publications (1)

Publication Number Publication Date
ATE336501T1 true ATE336501T1 (de) 2006-09-15

Family

ID=3810492

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99952156T ATE336501T1 (de) 1998-10-02 1999-10-01 Chi-conotoxinpeptide als inhibitoren neuronaler amintransporter

Country Status (13)

Country Link
US (4) US6794361B1 (de)
EP (1) EP1117682B1 (de)
JP (2) JP4447783B2 (de)
AT (1) ATE336501T1 (de)
AU (1) AUPP627498A0 (de)
CA (1) CA2344765A1 (de)
CY (1) CY1110381T1 (de)
DE (1) DE69932834T2 (de)
DK (1) DK1117682T3 (de)
ES (1) ES2268885T3 (de)
NZ (1) NZ510813A (de)
PT (1) PT1117682E (de)
WO (1) WO2000020444A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPP627498A0 (en) * 1998-10-02 1998-10-22 University Of Queensland, The Novel peptides - i
US6767896B1 (en) 1999-01-29 2004-07-27 Cognetix, Inc. Conotoxin peptides
WO2002060923A2 (en) * 2001-01-29 2002-08-08 Cognetix, Inc. B-superfamily conotoxins
ATE547424T1 (de) * 2002-12-02 2012-03-15 Xenome Ltd Chi-conotoxinpeptide mit einer n-terminalen pyroglutaminsäure
EP2412719A1 (de) 2002-12-02 2012-02-01 Xenome Ltd Chi-Conotoxin-Peptide
EP1791857A4 (de) * 2004-09-09 2009-04-08 Univ Singapore Konformationswechsel in der toxinfaltung und verwendungen dafür
US8188048B2 (en) 2006-06-23 2012-05-29 Xenome Limited Combination therapy
CN103372198B (zh) * 2012-04-12 2016-04-06 同济大学 用于抑制病毒的多肽抑制剂
JP6731044B2 (ja) 2015-05-22 2020-07-29 クレムソン・ユニバーシティ・リサーチ・ファウンデーション 生物付着の抑止において用いるためのコノトキシンペプチド
EA201890587A1 (ru) 2015-08-27 2018-09-28 Президент Энд Феллоуз Оф Гарвард Колледж Композиции и способы для лечения боли

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5051403A (en) 1989-11-22 1991-09-24 Neurex Corporation Method of treating ischemia-related neuronal damage
AU642582B2 (en) 1991-02-25 1993-10-21 Eli Lilly And Company Treatment of lower urinary tract disorders
SG50624A1 (en) * 1991-12-30 1998-07-20 Neurex Corp Methods of producing analgesia and enhancing opiate analgesia
EP1086702B1 (de) * 1994-05-09 2005-04-13 BINDER, William J. Präsynaptische Neurotoxine gegen Migränekopfschmerzen
JP3833248B2 (ja) 1994-11-03 2006-10-11 ノバルティス・アクチエンゲゼルシャフト 簡単な組成及び高い生物有効性を有する経口投与のためのシクロスポリンの新規処方物及びその製造法
WO1996040064A1 (en) 1995-06-07 1996-12-19 Nexstar Pharmaceuticals, Inc. Liposomal cyclosporin formulations as agents for immunosuppression and multiple drug resistant indications
DK0835126T3 (da) 1995-06-27 2003-07-14 Elan Pharm Inc Sammensætninger og formuleringer til fremstilling af analgesimidler og til hamning af fremadskridende neuropatiske amertelidelser
BR9707636A (pt) 1996-02-22 1999-07-27 Neurosearch As Composto composição farmacêutica uso de um composto e processos para preparar composto e para tratar um distúrbio ou doença de um organismo animal vivo
GB9614902D0 (en) 1996-07-16 1996-09-04 Rhodes John Sustained release composition
CZ288739B6 (cs) 1996-08-01 2001-08-15 Galena, A. S. Cyklosporin obsahující léčivé přípravky
WO1998022126A1 (en) 1996-11-18 1998-05-28 University Of Utah Research Foundation USE OF CONOTOXIN PEPTIDES ImI AND MII AS CARDIOVASCULAR AGENTS
AU7206398A (en) 1997-05-14 1998-12-08 Neurosearch A/S Piperidine derivatives as neurotransmitter re-uptake inhibitors
AUPP627498A0 (en) * 1998-10-02 1998-10-22 University Of Queensland, The Novel peptides - i
WO2000044769A1 (en) 1999-01-29 2000-08-03 University Of Utah Research Foundation Conotoxin peptides
EP2412719A1 (de) * 2002-12-02 2012-02-01 Xenome Ltd Chi-Conotoxin-Peptide
ATE547424T1 (de) * 2002-12-02 2012-03-15 Xenome Ltd Chi-conotoxinpeptide mit einer n-terminalen pyroglutaminsäure

Also Published As

Publication number Publication date
DE69932834T2 (de) 2007-08-23
US20050054827A1 (en) 2005-03-10
US6794361B1 (en) 2004-09-21
US7326682B2 (en) 2008-02-05
JP4447783B2 (ja) 2010-04-07
WO2000020444A1 (en) 2000-04-13
US20120277166A1 (en) 2012-11-01
EP1117682A1 (de) 2001-07-25
CA2344765A1 (en) 2000-04-13
AUPP627498A0 (en) 1998-10-22
US20090275498A1 (en) 2009-11-05
JP2010046088A (ja) 2010-03-04
ES2268885T3 (es) 2007-03-16
DE69932834D1 (de) 2006-09-28
DK1117682T3 (da) 2006-12-27
JP2002526098A (ja) 2002-08-20
EP1117682B1 (de) 2006-08-16
PT1117682E (pt) 2006-12-29
EP1117682A4 (de) 2001-12-12
NZ510813A (en) 2003-08-29
US7994128B2 (en) 2011-08-09
CY1110381T1 (el) 2015-04-29

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