ATE336590T1 - Verfahren zum thermodynamischen hochdurchsatzscreening von liganden - Google Patents
Verfahren zum thermodynamischen hochdurchsatzscreening von ligandenInfo
- Publication number
- ATE336590T1 ATE336590T1 AT00992272T AT00992272T ATE336590T1 AT E336590 T1 ATE336590 T1 AT E336590T1 AT 00992272 T AT00992272 T AT 00992272T AT 00992272 T AT00992272 T AT 00992272T AT E336590 T1 ATE336590 T1 AT E336590T1
- Authority
- AT
- Austria
- Prior art keywords
- ligands
- carrying
- throughput
- present
- binding
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 6
- 239000003446 ligand Substances 0.000 title abstract 5
- 238000012216 screening Methods 0.000 title abstract 2
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 238000005516 engineering process Methods 0.000 abstract 1
- 230000002349 favourable effect Effects 0.000 abstract 1
- 238000013537 high throughput screening Methods 0.000 abstract 1
- 230000035772 mutation Effects 0.000 abstract 1
- 238000005457 optimization Methods 0.000 abstract 1
- 238000000159 protein binding assay Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/451,837 US6242190B1 (en) | 1999-12-01 | 1999-12-01 | Method for high throughput thermodynamic screening of ligands |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE336590T1 true ATE336590T1 (de) | 2006-09-15 |
Family
ID=23793903
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00992272T ATE336590T1 (de) | 1999-12-01 | 2000-12-01 | Verfahren zum thermodynamischen hochdurchsatzscreening von liganden |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US6242190B1 (de) |
| EP (1) | EP1234180B1 (de) |
| JP (1) | JP2003532053A (de) |
| AT (1) | ATE336590T1 (de) |
| AU (1) | AU783111B2 (de) |
| CA (1) | CA2393422A1 (de) |
| DE (1) | DE60030149D1 (de) |
| MX (1) | MXPA02005449A (de) |
| WO (1) | WO2001040758A2 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6036920A (en) * | 1996-05-09 | 2000-03-14 | 3-Dimensional Pharmaceuticals, Inc. | Microplate thermal shift assay apparatus for ligand development and multi-variable protein chemistry optimization |
| AU1760001A (en) * | 1999-11-10 | 2001-06-06 | Quest Diagnostics Investments Incorporated | Use of computationally derived protein structures of genetic polymorphisms in pharmacogenomics and clinical applications |
| US6582907B1 (en) | 1999-12-09 | 2003-06-24 | Pharmacia & Upjohn Company | Use of fluorescence correlation spectroscopy to identify compounds that bind to target species under isothermal denaturing conditions |
| US6376180B1 (en) | 1999-12-09 | 2002-04-23 | Pharmacia & Upjohn Company | Methods of identifying compounds that bind to target species under isothermal denaturing conditions |
| EP1326642A2 (de) * | 2000-09-29 | 2003-07-16 | Board of Trustees operating Michigan State University | Catecholamin pharmazeutische zusammensetzungen und verfahren |
| US7392199B2 (en) * | 2001-05-01 | 2008-06-24 | Quest Diagnostics Investments Incorporated | Diagnosing inapparent diseases from common clinical tests using Bayesian analysis |
| EP1265073A3 (de) * | 2001-06-05 | 2003-11-26 | Tibotec Pharmaceuticals Ltd. | Verfahren zum Nachweis von der Plasmakonzentration von freien Arzneimitteln |
| WO2002103321A2 (en) * | 2001-06-14 | 2002-12-27 | Anadys Pharmaceuticals, Inc. | Methods of screening for ligands of target molecules |
| WO2003081211A2 (en) * | 2002-03-19 | 2003-10-02 | Cengent Therapeutics, Inc. | Discrete bayesian analysis of data |
| RU2297239C1 (ru) * | 2006-05-30 | 2007-04-20 | Общество С Ограниченной Ответственностью "Сиа Пептайдс" | Пептид, стимулирующий регенерацию ткани печени, фармацевтическая композиция на его основе и способ ее применения |
| JP5412579B2 (ja) * | 2009-08-25 | 2014-02-12 | エフ．ホフマン−ラ ロシュ アーゲー | 速度因子 |
| EP2608679B1 (de) | 2010-08-26 | 2018-08-15 | Dow Global Technologies LLC | Verfahren zur verlängerung der haltbarkeit von probiotika |
| CN112945923B (zh) * | 2021-02-03 | 2024-06-14 | 长沙理工大学 | 一种界面增敏型检测试剂及其制备方法和应用 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5518882A (en) * | 1993-12-21 | 1996-05-21 | Biotex Laboratories, Inc. | Immunological methods of component selection and recovery |
-
1999
- 1999-12-01 US US09/451,837 patent/US6242190B1/en not_active Expired - Fee Related
-
2000
- 2000-12-01 EP EP00992272A patent/EP1234180B1/de not_active Expired - Lifetime
- 2000-12-01 JP JP2001542174A patent/JP2003532053A/ja active Pending
- 2000-12-01 WO PCT/US2000/042424 patent/WO2001040758A2/en not_active Ceased
- 2000-12-01 AU AU39720/01A patent/AU783111B2/en not_active Ceased
- 2000-12-01 MX MXPA02005449A patent/MXPA02005449A/es active IP Right Grant
- 2000-12-01 DE DE60030149T patent/DE60030149D1/de not_active Expired - Lifetime
- 2000-12-01 AT AT00992272T patent/ATE336590T1/de not_active IP Right Cessation
- 2000-12-01 CA CA002393422A patent/CA2393422A1/en not_active Abandoned
-
2001
- 2001-01-25 US US09/768,557 patent/US20010008763A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1234180A2 (de) | 2002-08-28 |
| WO2001040758A3 (en) | 2002-01-17 |
| AU3972001A (en) | 2001-06-12 |
| JP2003532053A (ja) | 2003-10-28 |
| US20010008763A1 (en) | 2001-07-19 |
| EP1234180A4 (de) | 2005-01-05 |
| WO2001040758A2 (en) | 2001-06-07 |
| MXPA02005449A (es) | 2004-06-21 |
| US6242190B1 (en) | 2001-06-05 |
| CA2393422A1 (en) | 2001-06-07 |
| EP1234180B1 (de) | 2006-08-16 |
| AU783111B2 (en) | 2005-09-22 |
| DE60030149D1 (de) | 2006-09-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |