ATE487792T1 - Verfahren und zusammensetzungen zur identifikation von rna-bindenden proteinen - Google Patents
Verfahren und zusammensetzungen zur identifikation von rna-bindenden proteinenInfo
- Publication number
- ATE487792T1 ATE487792T1 AT04815473T AT04815473T ATE487792T1 AT E487792 T1 ATE487792 T1 AT E487792T1 AT 04815473 T AT04815473 T AT 04815473T AT 04815473 T AT04815473 T AT 04815473T AT E487792 T1 ATE487792 T1 AT E487792T1
- Authority
- AT
- Austria
- Prior art keywords
- methods
- compositions
- binding proteins
- identifying rna
- polypeptide
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 102000044126 RNA-Binding Proteins Human genes 0.000 title 1
- 108700020471 RNA-Binding Proteins Proteins 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/65—Peptidic linkers, binders or spacers, e.g. peptidic enzyme-labile linkers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/66—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid the modifying agent being a pre-targeting system involving a peptide or protein for targeting specific cells
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
- C07K14/003—Peptide-nucleic acids (PNAs)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
- C07K14/43568—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects from wasps
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Nanotechnology (AREA)
- Toxicology (AREA)
- Insects & Arthropods (AREA)
- Cell Biology (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Endocrinology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53171903P | 2003-12-22 | 2003-12-22 | |
| PCT/US2004/043401 WO2005062947A2 (en) | 2003-12-22 | 2004-12-22 | Methods and compositions for identifying rna-binding proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE487792T1 true ATE487792T1 (de) | 2010-11-15 |
Family
ID=34738685
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04815473T ATE487792T1 (de) | 2003-12-22 | 2004-12-22 | Verfahren und zusammensetzungen zur identifikation von rna-bindenden proteinen |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US8632972B2 (de) |
| EP (1) | EP1704160B1 (de) |
| JP (1) | JP2007515186A (de) |
| CN (1) | CN1914222A (de) |
| AT (1) | ATE487792T1 (de) |
| AU (1) | AU2004308473A1 (de) |
| CA (1) | CA2551094A1 (de) |
| DE (1) | DE602004030041D1 (de) |
| IL (1) | IL176479A0 (de) |
| WO (1) | WO2005062947A2 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2191016B1 (de) * | 2007-08-20 | 2015-03-04 | The General Hospital Corporation | Isolierung von proteinfaktoren in direkter oder indirekter assoziation mit nukleinsäuren |
| WO2009030254A1 (en) | 2007-09-04 | 2009-03-12 | Curevac Gmbh | Complexes of rna and cationic peptides for transfection and for immunostimulation |
| US20110053829A1 (en) | 2009-09-03 | 2011-03-03 | Curevac Gmbh | Disulfide-linked polyethyleneglycol/peptide conjugates for the transfection of nucleic acids |
| US9547007B2 (en) * | 2009-09-22 | 2017-01-17 | The Trustees Of The University Of Pennslyvania | Methods and compositions for in-vivo enzyme capture |
| EP2449113B8 (de) * | 2010-07-30 | 2015-11-25 | CureVac AG | Komplexierung von nucleinsäuren mit disulfid-vernetzten kationischen bestandteilen zur transfektion und immunstimulation |
| WO2013113326A1 (en) | 2012-01-31 | 2013-08-08 | Curevac Gmbh | Pharmaceutical composition comprising a polymeric carrier cargo complex and at least one protein or peptide antigen |
| BR112016003361A2 (pt) | 2013-08-21 | 2017-11-21 | Curevac Ag | vacina do vírus sincicial respiratório (rsv) |
| WO2015149944A2 (en) | 2014-04-01 | 2015-10-08 | Curevac Gmbh | Polymeric carrier cargo complex for use as an immunostimulating agent or as an adjuvant |
| CN106093436B (zh) * | 2016-07-25 | 2018-12-11 | 高飞 | 一种简便检测rna与蛋白互作的试剂盒及其使用方法 |
| WO2018035380A1 (en) | 2016-08-17 | 2018-02-22 | Solstice Biologics, Ltd. | Polynucleotide constructs |
| CN106478824B (zh) * | 2016-10-14 | 2020-04-24 | 潍坊医学院 | 一种精准Fc位点共价偶联标记的生物素化抗体 |
| CN108427000B (zh) * | 2017-02-15 | 2021-06-08 | 广州市锐博生物科技有限公司 | 一种捕获核酸结合蛋白的方法和试剂盒 |
| CN106632695B (zh) * | 2017-02-15 | 2021-01-05 | 中国药科大学 | 一种pH敏感性多肽及其应用 |
| US11597744B2 (en) | 2017-06-30 | 2023-03-07 | Sirius Therapeutics, Inc. | Chiral phosphoramidite auxiliaries and methods of their use |
| WO2020172642A1 (en) * | 2019-02-22 | 2020-08-27 | The Regents Of The University Of California | Peptide-functionalized biodegradable polymers for efficient delivery of various rnas |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4458066A (en) | 1980-02-29 | 1984-07-03 | University Patents, Inc. | Process for preparing polynucleotides |
| US4415732A (en) | 1981-03-27 | 1983-11-15 | University Patents, Inc. | Phosphoramidite compounds and processes |
| EP0260032B1 (de) | 1986-09-08 | 1994-01-26 | Ajinomoto Co., Inc. | Verbindungen zur Spaltung von RNS an eine spezifische Position, Oligomere, verwendet bei der Herstellung dieser Verbindungen und Ausgangsprodukte für die Synthese dieser Oligomere |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5366860A (en) | 1989-09-29 | 1994-11-22 | Applied Biosystems, Inc. | Spectrally resolvable rhodamine dyes for nucleic acid sequence determination |
| US5188934A (en) | 1989-11-14 | 1993-02-23 | Applied Biosystems, Inc. | 4,7-dichlorofluorescein dyes as molecular probes |
| US7223833B1 (en) * | 1991-05-24 | 2007-05-29 | Isis Pharmaceuticals, Inc. | Peptide nucleic acid conjugates |
| AU741546B2 (en) * | 1997-07-24 | 2001-12-06 | Perseptive Biosystems, Inc. | Conjugates of transporter peptides and nucleic acid analogs, and their use |
| AU2003223923A1 (en) * | 2002-05-01 | 2003-11-17 | Pantheco A/S | Peptide nucleic acid conjugates with transporter peptides |
-
2004
- 2004-12-22 CA CA002551094A patent/CA2551094A1/en not_active Abandoned
- 2004-12-22 CN CNA2004800412805A patent/CN1914222A/zh active Pending
- 2004-12-22 WO PCT/US2004/043401 patent/WO2005062947A2/en not_active Ceased
- 2004-12-22 AT AT04815473T patent/ATE487792T1/de not_active IP Right Cessation
- 2004-12-22 EP EP04815473A patent/EP1704160B1/de not_active Expired - Lifetime
- 2004-12-22 DE DE602004030041T patent/DE602004030041D1/de not_active Expired - Lifetime
- 2004-12-22 AU AU2004308473A patent/AU2004308473A1/en not_active Abandoned
- 2004-12-22 JP JP2006547393A patent/JP2007515186A/ja active Pending
-
2006
- 2006-06-20 US US11/472,097 patent/US8632972B2/en active Active
- 2006-06-21 IL IL176479A patent/IL176479A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US8632972B2 (en) | 2014-01-21 |
| JP2007515186A (ja) | 2007-06-14 |
| EP1704160B1 (de) | 2010-11-10 |
| EP1704160A2 (de) | 2006-09-27 |
| WO2005062947A2 (en) | 2005-07-14 |
| CA2551094A1 (en) | 2005-07-14 |
| CN1914222A (zh) | 2007-02-14 |
| US20080199854A1 (en) | 2008-08-21 |
| WO2005062947A3 (en) | 2005-09-09 |
| IL176479A0 (en) | 2006-10-05 |
| AU2004308473A1 (en) | 2005-07-14 |
| EP1704160A4 (de) | 2007-10-03 |
| DE602004030041D1 (de) | 2010-12-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |