ATE487792T1 - Verfahren und zusammensetzungen zur identifikation von rna-bindenden proteinen - Google Patents
Verfahren und zusammensetzungen zur identifikation von rna-bindenden proteinenInfo
- Publication number
- ATE487792T1 ATE487792T1 AT04815473T AT04815473T ATE487792T1 AT E487792 T1 ATE487792 T1 AT E487792T1 AT 04815473 T AT04815473 T AT 04815473T AT 04815473 T AT04815473 T AT 04815473T AT E487792 T1 ATE487792 T1 AT E487792T1
- Authority
- AT
- Austria
- Prior art keywords
- methods
- compositions
- binding proteins
- identifying rna
- polypeptide
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 102000044126 RNA-Binding Proteins Human genes 0.000 title 1
- 108700020471 RNA-Binding Proteins Proteins 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/65—Peptidic linkers, binders or spacers, e.g. peptidic enzyme-labile linkers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/66—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid the modifying agent being a pre-targeting system involving a peptide or protein for targeting specific cells
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
- C07K14/003—Peptide-nucleic acids (PNAs)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
- C07K14/43568—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects from wasps
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nanotechnology (AREA)
- Toxicology (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Cell Biology (AREA)
- Insects & Arthropods (AREA)
- Public Health (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Immunology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53171903P | 2003-12-22 | 2003-12-22 | |
| PCT/US2004/043401 WO2005062947A2 (en) | 2003-12-22 | 2004-12-22 | Methods and compositions for identifying rna-binding proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE487792T1 true ATE487792T1 (de) | 2010-11-15 |
Family
ID=34738685
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04815473T ATE487792T1 (de) | 2003-12-22 | 2004-12-22 | Verfahren und zusammensetzungen zur identifikation von rna-bindenden proteinen |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US8632972B2 (de) |
| EP (1) | EP1704160B1 (de) |
| JP (1) | JP2007515186A (de) |
| CN (1) | CN1914222A (de) |
| AT (1) | ATE487792T1 (de) |
| AU (1) | AU2004308473A1 (de) |
| CA (1) | CA2551094A1 (de) |
| DE (1) | DE602004030041D1 (de) |
| IL (1) | IL176479A0 (de) |
| WO (1) | WO2005062947A2 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009024781A1 (en) * | 2007-08-20 | 2009-02-26 | The General Hospital Corporation | Isolation of protein factors that associate directly or indirectly with nucleic acids |
| WO2009030254A1 (en) | 2007-09-04 | 2009-03-12 | Curevac Gmbh | Complexes of rna and cationic peptides for transfection and for immunostimulation |
| US20110053829A1 (en) | 2009-09-03 | 2011-03-03 | Curevac Gmbh | Disulfide-linked polyethyleneglycol/peptide conjugates for the transfection of nucleic acids |
| US9547007B2 (en) * | 2009-09-22 | 2017-01-17 | The Trustees Of The University Of Pennslyvania | Methods and compositions for in-vivo enzyme capture |
| JP5948327B2 (ja) | 2010-07-30 | 2016-07-06 | キュアヴァック アーゲー | トランスフェクションおよび免疫刺激のためのジスルフィド架橋されたカチオン性成分との核酸の複合体形成 |
| WO2013113326A1 (en) | 2012-01-31 | 2013-08-08 | Curevac Gmbh | Pharmaceutical composition comprising a polymeric carrier cargo complex and at least one protein or peptide antigen |
| SG11201510746WA (en) | 2013-08-21 | 2016-03-30 | Curevac Ag | Respiratory syncytial virus (rsv) vaccine |
| WO2015149944A2 (en) | 2014-04-01 | 2015-10-08 | Curevac Gmbh | Polymeric carrier cargo complex for use as an immunostimulating agent or as an adjuvant |
| CN106093436B (zh) * | 2016-07-25 | 2018-12-11 | 高飞 | 一种简便检测rna与蛋白互作的试剂盒及其使用方法 |
| EP3500581A4 (de) | 2016-08-17 | 2021-10-06 | Solstice Biologics, Ltd. | Polynukleotidkonstrukte |
| CN106478824B (zh) * | 2016-10-14 | 2020-04-24 | 潍坊医学院 | 一种精准Fc位点共价偶联标记的生物素化抗体 |
| CN108427000B (zh) * | 2017-02-15 | 2021-06-08 | 广州市锐博生物科技有限公司 | 一种捕获核酸结合蛋白的方法和试剂盒 |
| CN106632695B (zh) * | 2017-02-15 | 2021-01-05 | 中国药科大学 | 一种pH敏感性多肽及其应用 |
| EP3645546A4 (de) | 2017-06-30 | 2021-12-01 | Solstice Biologics, Ltd. | Chirale phosphoramidithilfsmittel und verfahren zu ihrer verwendung |
| WO2020172642A1 (en) * | 2019-02-22 | 2020-08-27 | The Regents Of The University Of California | Peptide-functionalized biodegradable polymers for efficient delivery of various rnas |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4458066A (en) | 1980-02-29 | 1984-07-03 | University Patents, Inc. | Process for preparing polynucleotides |
| US4415732A (en) | 1981-03-27 | 1983-11-15 | University Patents, Inc. | Phosphoramidite compounds and processes |
| EP0260032B1 (de) | 1986-09-08 | 1994-01-26 | Ajinomoto Co., Inc. | Verbindungen zur Spaltung von RNS an eine spezifische Position, Oligomere, verwendet bei der Herstellung dieser Verbindungen und Ausgangsprodukte für die Synthese dieser Oligomere |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5366860A (en) | 1989-09-29 | 1994-11-22 | Applied Biosystems, Inc. | Spectrally resolvable rhodamine dyes for nucleic acid sequence determination |
| US5188934A (en) | 1989-11-14 | 1993-02-23 | Applied Biosystems, Inc. | 4,7-dichlorofluorescein dyes as molecular probes |
| US7223833B1 (en) * | 1991-05-24 | 2007-05-29 | Isis Pharmaceuticals, Inc. | Peptide nucleic acid conjugates |
| AU741546B2 (en) * | 1997-07-24 | 2001-12-06 | Perseptive Biosystems, Inc. | Conjugates of transporter peptides and nucleic acid analogs, and their use |
| AU2003223923A1 (en) * | 2002-05-01 | 2003-11-17 | Pantheco A/S | Peptide nucleic acid conjugates with transporter peptides |
-
2004
- 2004-12-22 CN CNA2004800412805A patent/CN1914222A/zh active Pending
- 2004-12-22 AT AT04815473T patent/ATE487792T1/de not_active IP Right Cessation
- 2004-12-22 EP EP04815473A patent/EP1704160B1/de not_active Expired - Lifetime
- 2004-12-22 AU AU2004308473A patent/AU2004308473A1/en not_active Abandoned
- 2004-12-22 JP JP2006547393A patent/JP2007515186A/ja active Pending
- 2004-12-22 CA CA002551094A patent/CA2551094A1/en not_active Abandoned
- 2004-12-22 WO PCT/US2004/043401 patent/WO2005062947A2/en not_active Ceased
- 2004-12-22 DE DE602004030041T patent/DE602004030041D1/de not_active Expired - Lifetime
-
2006
- 2006-06-20 US US11/472,097 patent/US8632972B2/en active Active
- 2006-06-21 IL IL176479A patent/IL176479A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2551094A1 (en) | 2005-07-14 |
| AU2004308473A1 (en) | 2005-07-14 |
| US20080199854A1 (en) | 2008-08-21 |
| US8632972B2 (en) | 2014-01-21 |
| EP1704160A4 (de) | 2007-10-03 |
| WO2005062947A3 (en) | 2005-09-09 |
| EP1704160B1 (de) | 2010-11-10 |
| EP1704160A2 (de) | 2006-09-27 |
| DE602004030041D1 (de) | 2010-12-23 |
| CN1914222A (zh) | 2007-02-14 |
| JP2007515186A (ja) | 2007-06-14 |
| WO2005062947A2 (en) | 2005-07-14 |
| IL176479A0 (en) | 2006-10-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |