ATE337333T1 - Ophthalmische arzneimittelzusammenstellung - Google Patents
Ophthalmische arzneimittelzusammenstellungInfo
- Publication number
- ATE337333T1 ATE337333T1 AT97926223T AT97926223T ATE337333T1 AT E337333 T1 ATE337333 T1 AT E337333T1 AT 97926223 T AT97926223 T AT 97926223T AT 97926223 T AT97926223 T AT 97926223T AT E337333 T1 ATE337333 T1 AT E337333T1
- Authority
- AT
- Austria
- Prior art keywords
- ophthalmic
- present
- leu
- gly
- met
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 239000004480 active ingredient Substances 0.000 abstract 3
- JIJRURCWBONLPN-BZSNNMDCSA-N L-Phe-Gly-L-Leu-L-Met-NH2 Chemical compound CSCC[C@@H](C(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@@H](N)CC1=CC=CC=C1 JIJRURCWBONLPN-BZSNNMDCSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 208000021921 corneal disease Diseases 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 108010051137 phenylalanyl-glycyl-leucyl-methioninamide Proteins 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 229940124597 therapeutic agent Drugs 0.000 abstract 2
- 102000004218 Insulin-Like Growth Factor I Human genes 0.000 abstract 1
- 108090000723 Insulin-Like Growth Factor I Proteins 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000001747 exhibiting effect Effects 0.000 abstract 1
- CWWARWOPSKGELM-SARDKLJWSA-N methyl (2s)-2-[[(2s)-2-[[2-[[(2s)-2-[[(2s)-2-[[(2s)-5-amino-2-[[(2s)-5-amino-2-[[(2s)-1-[(2s)-6-amino-2-[[(2s)-1-[(2s)-2-amino-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoyl]amino]-5 Chemical compound C([C@@H](C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)OC)NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CCCCN)NC(=O)[C@H]1N(CCC1)C(=O)[C@@H](N)CCCN=C(N)N)C1=CC=CC=C1 CWWARWOPSKGELM-SARDKLJWSA-N 0.000 abstract 1
- 230000005012 migration Effects 0.000 abstract 1
- 238000013508 migration Methods 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/046—Tachykinins, e.g. eledoisins, substance P; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/07—Tetrapeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/22—Tachykinins, e.g. Eledoisins, Substance P; Related peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Ophthalmology & Optometry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP16561296A JP3191038B2 (ja) | 1996-06-26 | 1996-06-26 | 眼科用医薬組成物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE337333T1 true ATE337333T1 (de) | 2006-09-15 |
Family
ID=15815677
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97926223T ATE337333T1 (de) | 1996-06-26 | 1997-06-11 | Ophthalmische arzneimittelzusammenstellung |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6221846B1 (de) |
| EP (1) | EP0914827B1 (de) |
| JP (1) | JP3191038B2 (de) |
| AT (1) | ATE337333T1 (de) |
| DE (1) | DE69736554T2 (de) |
| ES (1) | ES2268730T3 (de) |
| WO (1) | WO1997049419A1 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7273618B2 (en) | 1998-12-09 | 2007-09-25 | Chiron Corporation | Method for administering agents to the central nervous system |
| AU2173400A (en) * | 1998-12-09 | 2000-06-26 | Chiron Corporation | Method for administering agents to the central nervous system |
| US7071166B2 (en) | 2000-08-10 | 2006-07-04 | Santen Pharmacetical Co., Ltd. | Skin wound healing promoters |
| JP4253743B2 (ja) * | 2001-12-03 | 2009-04-15 | 輝夫 西田 | 新規ペプチドおよびその医薬用途 |
| TWI305778B (en) | 2001-12-03 | 2009-02-01 | Nishida Teruo | Peptides of an expressing unit for igf-i minimal activity and their pharmaceutical use |
| JP4313033B2 (ja) * | 2002-12-27 | 2009-08-12 | 株式会社日本点眼薬研究所 | 眼科用治療組成物 |
| WO2007062060A2 (en) | 2005-11-22 | 2007-05-31 | Ted Reid | Methods and compositions using substance p to promote wound healing |
| BR112012006187A2 (pt) * | 2009-09-25 | 2019-09-24 | Santen Pharmaceutical Co., Ltd. | colírio, e método para estabilizar um colírio,tendo um excelente efeito sobre a promoção da cura de um distúrbio da córnea |
| CA2779417A1 (en) * | 2009-11-11 | 2011-05-19 | Yamaguchi University | Therapeutic agent for gastrointestinal disease |
| SG11201706819RA (en) * | 2015-02-25 | 2017-09-28 | Tsung-Chuan Ho | Use of short synthetic peptide for the treatment and/or prophylaxis of dry eye disease |
| KR101869783B1 (ko) * | 2016-08-17 | 2018-06-22 | (주)진셀팜 | 미백 활성이 우수한 펩타이드, 및 이의 용도 |
| WO2019061491A1 (en) * | 2017-09-30 | 2019-04-04 | Pro Sunfun Biotech Research And Development Co., Ltd. | PEPTIDE FOR OCULAR CARE, COMPOSITION AND METHOD OF USE THEREOF |
| CN109912685B (zh) * | 2017-12-13 | 2022-05-06 | 三凡生技研发股份有限公司 | 眼睛保护胜肽及其组合物及使用该胜肽的用途 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3862114A (en) | 1971-11-22 | 1975-01-21 | Ici Australia Ltd | Analogs of substance p |
| EP0176436A3 (de) * | 1984-09-26 | 1987-12-16 | Merck & Co. Inc. | Analoge der Verbindung P und von Eledoisin |
| US4885163A (en) | 1987-02-24 | 1989-12-05 | Eli Lilly And Company | Topical use of IGF-II for wound healing |
| NZ226171A (en) | 1987-09-18 | 1990-06-26 | Ethicon Inc | Gel formulation containing polypeptide growth factor |
| US5104787A (en) | 1990-03-05 | 1992-04-14 | Lindstrom Richard L | Method for apparatus for a defined serumfree medical solution useful for corneal preservation |
| US5616562A (en) | 1990-04-27 | 1997-04-01 | Murphy; Christopher J. | Methods and compositions using substance P to promote wound healing |
| GB9113219D0 (en) * | 1991-06-19 | 1991-08-07 | Fujisawa Pharmaceutical Co | Peptide compound,processes for preparation thereof and pharmaceutical composition comprising the same |
| JPH0525001A (ja) | 1991-07-08 | 1993-02-02 | L Lyndstrom Richard | 血清不含有医療用溶液および眼組織の品質を高める方法 |
| US6310040B1 (en) | 1991-11-08 | 2001-10-30 | Cephalon, Inc. | Treating retinal neuronal disorders by the application of insulin-like growth factors and analogs |
| US5545617A (en) | 1993-11-12 | 1996-08-13 | The Schepens Eye Research Institute, Inc. | Therapeutic regulation of abnormal conjunctival goblet cell mucous secretion |
-
1996
- 1996-06-26 JP JP16561296A patent/JP3191038B2/ja not_active Expired - Fee Related
-
1997
- 1997-06-11 US US09/202,820 patent/US6221846B1/en not_active Expired - Lifetime
- 1997-06-11 ES ES97926223T patent/ES2268730T3/es not_active Expired - Lifetime
- 1997-06-11 EP EP97926223A patent/EP0914827B1/de not_active Expired - Lifetime
- 1997-06-11 AT AT97926223T patent/ATE337333T1/de not_active IP Right Cessation
- 1997-06-11 WO PCT/JP1997/002015 patent/WO1997049419A1/ja not_active Ceased
- 1997-06-11 DE DE69736554T patent/DE69736554T2/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ES2268730T3 (es) | 2007-03-16 |
| EP0914827A4 (de) | 1999-08-04 |
| DE69736554D1 (de) | 2006-10-05 |
| JP3191038B2 (ja) | 2001-07-23 |
| EP0914827A1 (de) | 1999-05-12 |
| DE69736554T2 (de) | 2007-08-23 |
| WO1997049419A1 (en) | 1997-12-31 |
| US6221846B1 (en) | 2001-04-24 |
| EP0914827B1 (de) | 2006-08-23 |
| JPH1017489A (ja) | 1998-01-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |