ATE338754T1 - Heterocyclische verbindungen, ihre herstellung und verwendung - Google Patents

Heterocyclische verbindungen, ihre herstellung und verwendung

Info

Publication number
ATE338754T1
ATE338754T1 AT02079001T AT02079001T ATE338754T1 AT E338754 T1 ATE338754 T1 AT E338754T1 AT 02079001 T AT02079001 T AT 02079001T AT 02079001 T AT02079001 T AT 02079001T AT E338754 T1 ATE338754 T1 AT E338754T1
Authority
AT
Austria
Prior art keywords
stands
heterocyclic compounds
chem
denotes
integer
Prior art date
Application number
AT02079001T
Other languages
English (en)
Inventor
Yu Momose
Etsuya Matsutani
Original Assignee
Takeda Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical
Application granted granted Critical
Publication of ATE338754T1 publication Critical patent/ATE338754T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT02079001T 1996-07-19 1997-07-17 Heterocyclische verbindungen, ihre herstellung und verwendung ATE338754T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP19110096 1996-07-19
JP15517797 1997-06-12

Publications (1)

Publication Number Publication Date
ATE338754T1 true ATE338754T1 (de) 2006-09-15

Family

ID=26483246

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02079001T ATE338754T1 (de) 1996-07-19 1997-07-17 Heterocyclische verbindungen, ihre herstellung und verwendung

Country Status (10)

Country Link
US (1) US6211215B1 (de)
EP (2) EP1270571B1 (de)
KR (1) KR20000065227A (de)
CN (2) CN1077107C (de)
AT (1) ATE338754T1 (de)
AU (1) AU3461697A (de)
CA (1) CA2260999C (de)
DE (1) DE69736642T2 (de)
ID (1) ID17851A (de)
WO (1) WO1998003505A2 (de)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI0991628T1 (en) * 1997-05-28 2005-06-30 Aventis Pharmaceuticals Inc QUINOLINE AND QUINOXALINE COMPOUNDS WHICH INHIBIT PLATELET-DERIVED GROWTH FACTOR AND/OR P56lck TYROSINE KINASES
US6180632B1 (en) 1997-05-28 2001-01-30 Aventis Pharmaceuticals Products Inc. Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and/or p56lck tyrosine kinases
FR2766822B1 (fr) * 1997-07-30 2001-02-23 Adir Nouveaux derives de benzimidazole, de benzoxazole et de benzothiazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CA2299471C (en) † 1997-08-15 2007-12-18 Cephalon Inc. Combination of tyrosine kinase inhibitor and chemical castration to treat prostate cancer
EP1136079A4 (de) * 1998-10-08 2004-09-22 Takeda Chemical Industries Ltd Substanzen zur verlangsamung des wechsels von einem hormon-abhängigen krebs in einen hormon-unabhängigen krebs
US6867203B2 (en) 1998-12-29 2005-03-15 Abbott Laboratories Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds
AU1412901A (en) * 1999-11-16 2001-05-30 Toray Industries, Inc. Benzene derivatives and use thereof as drugs
PE20011178A1 (es) * 2000-04-07 2001-11-19 Takeda Chemical Industries Ltd Compuestos heterociclicos y su produccion
EP1294704A1 (de) 2000-06-29 2003-03-26 Abbott Laboratories Aryl-phenylheterocyclyl-sulfid-derivate und deren anwendung als zelladhäsionshemmende anti-inflammatorische und immunsuppressive mittel
EP1310491A1 (de) * 2000-07-19 2003-05-14 Takeda Chemical Industries, Ltd. Verfahren zur produktion eines 1-substituierten-1,2,3-triazolderivats
CN1487936A (zh) * 2000-12-11 2004-04-07 ����ҩƷ��ҵ��ʽ���� 具有改进吸收性能的药物组合物
EP1712550A3 (de) * 2000-12-22 2009-07-15 Ortho-McNeil Pharmaceutical, Inc. Substituite Triazoldiamin Derivate und ihre Verwendung als Kinase-Inhibitoren
WO2002053547A1 (en) * 2000-12-28 2002-07-11 Takeda Chemical Industries, Ltd. Alkanoic acid derivatives, process for their production and use thereof
SE0100567D0 (sv) * 2001-02-20 2001-02-20 Astrazeneca Ab Compounds
US20040116330A1 (en) * 2001-04-27 2004-06-17 Kenichiro Naito Preventive/therapeutic method for cancer
US20040138160A1 (en) * 2001-04-27 2004-07-15 Kenichiro Naito Preventive/therapeutic method for cancer
CN101444496B (zh) 2001-06-12 2011-04-13 维尔斯达医疗公司 用于治疗代谢失调的化合物
EP1439178A4 (de) * 2001-10-05 2005-11-16 Takeda Pharmaceutical Heterocyclische verbindungen, oxazolderivate, verfahren zu deren herstellung und deren verwendung
US7812044B2 (en) 2001-11-13 2010-10-12 Takeda Pharmaceutical Company Limited Anticancer agents
EP1460067A4 (de) * 2001-11-26 2005-12-07 Takeda Pharmaceutical Bicyclische derivate, verfahren zu deren herstellung und deren verwendung
WO2003059907A1 (en) * 2002-01-17 2003-07-24 Takeda Chemical Industries, Ltd. Nitrogenous heterocyclic compounds, process for preparation of the same and use thereof
DE10258168B4 (de) * 2002-12-12 2005-07-07 Infineon Technologies Ag Integrierter DRAM-Halbleiterspeicher und Verfahren zum Betrieb desselben
CN1750758B (zh) 2003-02-13 2012-06-20 维尔斯达医疗公司 用于治疗代谢紊乱的化合物
TW200505913A (en) * 2003-03-28 2005-02-16 Hoffmann La Roche Novel oxazole derivatives, their manufacture and use as pharmaceutical agents
TW200423931A (en) * 2003-04-30 2004-11-16 Hoffmann La Roche Novel aniline derivatives, their manufacture and use as pharmaceutical agents
US7247649B2 (en) 2003-08-13 2007-07-24 Hoffmann-La Roche Inc. Oxazoles, their manufacture and use as pharmaceutical agents
EP1658285B1 (de) 2003-08-20 2007-05-02 Eli Lilly And Company Verbindungen, verfahren und formulierungen zur oralen verabreichung einer glucagonartigen peptid (glp)-1-verbindung oder eines melanocortin-4-rezeptor-(mc4-)agonistschen peptids
ATE350369T1 (de) 2003-08-20 2007-01-15 Lilly Co Eli Verbindungen, verfahren und formulierungen zur oralen verabreichung einer glucagon like peptide (glp)-1-verbindung oder eines am melanocortin-4- rezeptor (mc4) als agonist wirkenden peptids
US7259262B2 (en) 2003-10-24 2007-08-21 Hoffmann-La Roche Inc. Arylazole derivatives, their manufacture and use as pharmaceutical agents
TW200531688A (en) 2004-03-05 2005-10-01 Hoffmann La Roche Novel pentafluorosulfanyl compounds, their manufacture and use as pharmaceutical agents
TW200612914A (en) 2004-03-05 2006-05-01 Hoffmann La Roche Novel oxidized thioether derivatives, their manufacture and use as pharmaceutical agents
TW200533346A (en) 2004-03-18 2005-10-16 Hoffmann La Roche Novel ether derivatives, their manufacture and use as pharmaceutical agents
US7179812B2 (en) 2004-04-02 2007-02-20 Hoffmann-La Roche Inc. Diazine derivatives
US7005526B2 (en) 2004-05-25 2006-02-28 Hoffmann-La Roche Inc. Thioether derivatives
US7163953B2 (en) 2004-05-25 2007-01-16 Hoffmann-La Roche Inc. Benzylether derivatives
US7288557B2 (en) 2004-09-21 2007-10-30 Hoffmann-La Roche Inc. Triazole derivatives
AR050944A1 (es) 2004-09-22 2006-12-06 Hoffmann La Roche Derivados de indol, su fabricacion y su utilizacion como agentes farmaceuticos
US20060069095A1 (en) * 2004-09-24 2006-03-30 Thomas Hofmeister Azole derivatives
US20060116407A1 (en) * 2004-11-22 2006-06-01 Birgit Bossenmaier Amide derivatives
KR20080041662A (ko) 2005-07-22 2008-05-13 다케다 야쿠힌 고교 가부시키가이샤 조기 배란 예방제
US7429605B2 (en) * 2005-08-04 2008-09-30 Hoffmann-La Roche Inc. Phenylpyridine derivatives
EP1915370A1 (de) * 2005-08-08 2008-04-30 F.Hoffmann-La Roche Ag Pyrazolderivate, deren herstellung und deren verwendung als pharmazeutische mittel
AU2006331656B2 (en) * 2005-12-22 2012-08-09 Icagen, Inc. Calcium channel antagonists
WO2008034579A1 (en) * 2006-09-20 2008-03-27 F. Hoffmann-La Roche Ag 2-heterocyclyl-5-phenoxymethylpyridine derivatives as anticancer agents
CA2727528A1 (en) * 2007-06-14 2008-12-18 Osta Biotechnologies Heme-oxygenase inhibitors and use of the same in the treatment of cancer and diseases of the central nervous system
EP2329823A4 (de) 2008-09-03 2013-04-03 Takeda Pharmaceutical Verfahren zur erhöhung der absorptionsfähigkeit eines präparats sowie präparat mit erhöhter absorptionsfähigkeit
US9364438B2 (en) 2012-09-26 2016-06-14 Takeda Pharmaceutical Company Limited Process for producing solid particles
CA2995617A1 (en) * 2017-11-03 2019-05-03 Universite De Montreal Heterocyclic mitochondrial activity inhibitors and uses thereof
KR102929140B1 (ko) * 2023-05-09 2026-02-24 주식회사 베노바이오 Bet 단백질을 저해하는 신규한 벤조사이오펜 유도체 및 이를 이용한 암 치료용 조성물
CN117624052B (zh) * 2024-01-26 2024-04-12 四川益能康生环保科技有限公司 一种用于捕集二氧化碳的离子液体及其制备方法
CN117820251B (zh) * 2024-03-01 2024-05-03 南京桦冠生物技术有限公司 双α-酮酸酰胺类化合物及其组合物
CN118165425B (zh) * 2024-03-13 2024-09-27 福建诏安传琪新材料有限公司 一种无卤阻燃三元乙丙橡胶发泡材料及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5359078A (en) * 1989-05-19 1994-10-25 The United States Of America As Represented By The Department Of Health And Human Services Signal transduction inhibitor compounds
WO1992003425A1 (en) 1990-08-23 1992-03-05 Pfizer Inc. Hypoglycemic hydroxyurea derivatives
WO1994003427A1 (en) * 1992-08-06 1994-02-17 Warner-Lambert Company 2-thioindoles (selenoindoles) and related disulfides (selenides) which inhibit protein tyrosine kinases and which have antitumor properties
IT1266582B1 (it) 1993-07-30 1997-01-09 Recordati Chem Pharm Derivati (di)azacicloesanici e diazacicloeptanici
US5466610A (en) 1993-09-07 1995-11-14 Eli Lilly And Company Immunoassays for insulin sensitivity enhancers, insulin sensitivity enhancer antibodies, and non-thiazolidinedione insulin sensitivity enhancer compositions
US5480896A (en) 1994-01-27 1996-01-02 American Home Products Corporation Aralkyl-1,2,4-oxadiazolidine-3,5-diones as antihyperglycemic agents
US5869485A (en) * 1994-09-29 1999-02-09 Novartis Finance Corp. Pyrrolo 2,3-d!pyrimidines and their use

Also Published As

Publication number Publication date
CA2260999C (en) 2006-07-11
AU3461697A (en) 1998-02-10
DE69736642D1 (de) 2006-10-19
EP1270571B1 (de) 2006-09-06
KR20000065227A (ko) 2000-11-06
CA2260999A1 (en) 1998-01-29
EP0912562A1 (de) 1999-05-06
CN1077107C (zh) 2002-01-02
CN1223653A (zh) 1999-07-21
EP1270571A1 (de) 2003-01-02
WO1998003505A3 (en) 1998-06-25
WO1998003505A2 (en) 1998-01-29
ID17851A (id) 1998-01-29
DE69736642T2 (de) 2007-09-20
US6211215B1 (en) 2001-04-03
CN1349990A (zh) 2002-05-22

Similar Documents

Publication Publication Date Title
ATE338754T1 (de) Heterocyclische verbindungen, ihre herstellung und verwendung
DE69111029D1 (de) Kondensierte heterocyclische Verbindungen, ihre Herstellung und Verwendung.
ATE325110T1 (de) Sauerstoff enthaltende heterocyclische verbindungen
DE69523358D1 (de) Heterozyklische Verbindungen mit antidiabetischer Wirkung, ihre Herstellung und Verwendung
NO953305D0 (no) Antranilsyrederivat
ATE129498T1 (de) Kondensierte heterozyklische verbindungen, ihre herstellung und verwendung.
ATE339409T1 (de) Trizyklische verbindungen
ATE226581T1 (de) Isoxazole derivate und ihre verwendung als herbizide
NO930974L (no) Fremstilling og anvendelse av triazolpyridazinforbindelser
DE69918695D1 (de) Sauerstoffhaltige heterocyclische verbindungen
HU9301866D0 (en) Benzoxa-condensed-ring-compounds and medical preparatives containing these compounds and processes for production of these compounds and of pharmaceutical composition
DE60239170D1 (de) Bicyclische Verbindungen
ATE121385T1 (de) Harnstoffderivate, ihre herstellung und ihre verwendung bei der therapie.
DE60037766D1 (de) Verfahren zur Herstellung von 2-Alkyl-3-aminothiophen Derivate und 3-Aminothiophen Derivate
ATE168679T1 (de) Neue tetracyclische verbindungen
ATE303376T1 (de) Tricyclische kondensierte heterocyclische verbindungen, verfahren zu ihrer herstellung und ihre verwendung
DE69607890D1 (de) Aromatische Hydroxamsäure-Verbindungen, ihre Herstellung und Verwendung
GR3031390T3 (en) Fluoropropene compound, an insecticide containing the same and an intermediate for production thereof
MY134476A (en) Aromatic compounds, their production processes and their compositions for the control of insect pests

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties