ATE338950T1 - Verfahren zum nachweis von allosteren effektoren eines rezeptors - Google Patents

Verfahren zum nachweis von allosteren effektoren eines rezeptors

Info

Publication number
ATE338950T1
ATE338950T1 AT03748170T AT03748170T ATE338950T1 AT E338950 T1 ATE338950 T1 AT E338950T1 AT 03748170 T AT03748170 T AT 03748170T AT 03748170 T AT03748170 T AT 03748170T AT E338950 T1 ATE338950 T1 AT E338950T1
Authority
AT
Austria
Prior art keywords
variation
receptor
kinetics
detecting
labeled
Prior art date
Application number
AT03748170T
Other languages
English (en)
Inventor
Jean-Luc Galzi
Marcel Hibert
Jean-Jacques Bourguignon
Emeline Maillet
Original Assignee
Centre Nat Rech Scient
Univ Pasteur
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre Nat Rech Scient, Univ Pasteur filed Critical Centre Nat Rech Scient
Application granted granted Critical
Publication of ATE338950T1 publication Critical patent/ATE338950T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06086—Dipeptides with the first amino acid being basic
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/557—Immunoassay; Biospecific binding assay; Materials therefor using kinetic measurement, i.e. time rate of progress of an antigen-antibody interaction

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Electrotherapy Devices (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Pyrane Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Auxiliary Devices For Music (AREA)
AT03748170T 2002-06-17 2003-06-16 Verfahren zum nachweis von allosteren effektoren eines rezeptors ATE338950T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0207436A FR2840993B1 (fr) 2002-06-17 2002-06-17 Procede de mise en evidence d'un effecteur allosterique d'un recepteur

Publications (1)

Publication Number Publication Date
ATE338950T1 true ATE338950T1 (de) 2006-09-15

Family

ID=29595303

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03748170T ATE338950T1 (de) 2002-06-17 2003-06-16 Verfahren zum nachweis von allosteren effektoren eines rezeptors

Country Status (11)

Country Link
US (1) US20060194259A1 (de)
EP (1) EP1514112B1 (de)
JP (1) JP2005530158A (de)
AT (1) ATE338950T1 (de)
AU (1) AU2003267483A1 (de)
CA (1) CA2489389A1 (de)
DE (1) DE60308182T2 (de)
DK (1) DK1514112T3 (de)
ES (1) ES2273026T3 (de)
FR (1) FR2840993B1 (de)
WO (1) WO2003107004A2 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102007022915A1 (de) * 2007-05-14 2008-11-20 Stiftung Caesar Center Of Advanced European Studies And Research Polymerisationssensor

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2764387B1 (fr) * 1997-06-05 1999-07-23 Centre Nat Rech Scient Utilisation d'une proteine fluorescente pour la detection d'interactions entre une proteine cible et son ligand
AU2030000A (en) * 1998-11-25 2000-06-13 Cadus Pharmaceutical Corporation Methods and compositions for identifying receptor effectors

Also Published As

Publication number Publication date
US20060194259A1 (en) 2006-08-31
FR2840993B1 (fr) 2005-04-08
DE60308182T2 (de) 2007-08-23
DK1514112T3 (da) 2007-01-15
ES2273026T3 (es) 2007-05-01
FR2840993A1 (fr) 2003-12-19
WO2003107004A2 (fr) 2003-12-24
CA2489389A1 (fr) 2003-12-24
JP2005530158A (ja) 2005-10-06
WO2003107004A3 (fr) 2004-06-24
DE60308182D1 (de) 2006-10-19
EP1514112A2 (de) 2005-03-16
AU2003267483A1 (en) 2003-12-31
EP1514112B1 (de) 2006-09-06

Similar Documents

Publication Publication Date Title
EP1067376A3 (de) Vorrichtung zur Messung von Fluoreszenz
EP1243925A3 (de) Biochemisches Untersuchungsverfahren
JP2008510965A5 (de)
DE60042738D1 (de) Verfahren zum nachweis von analyten mit hilfe von halbleiternanokrystallen
ATE509120T1 (de) Fusionsproteine zur detektion von analyten
RU2003100531A (ru) Композиции, содержащие краситель на основе производного мочевины, для выявления аналита, и способы их использования
CN111308103A (zh) 心肺五联检测试剂盒及其稀土纳米荧光检测卡和检测方法
US20060198760A1 (en) Opto-acoustic sensor device and associated method
ATE397208T1 (de) Messverfahren basierend auf fluoreszenz- energie- transfer mit einem donor langer fluoreszenzlebenszeit
DE59403667D1 (de) Verfahren zum nachweis von substanzen
WO1998055873A3 (fr) Utilisation d'une proteine fluorescente pour la detection d'interactions entre une proteine cible et son ligand
DE60308182D1 (de) Verfahren zum nachweis von allosteren effektoren eines rezeptors
WO2004040534A3 (en) Metal chelates and methods of using them for time-resolved fluorescence
ES2177596T3 (es) Procedimiento para reducir la influencia de ensayos diagnosticos por parte de heparina con empleo de sales metalicas, y reactivo diagnosticopara ensayos diagnosticos para la determinacion de la capacidad de coagulacion de la sangre que contiene sales metalicas.
CA2541075A1 (en) Homogeneous time-resolved energy transfer assay
AR016779A1 (es) Monitoreo de depositos vivientes formadores de pelicula.
EP1805504A1 (de) Verfahren zur relativen messung der fluoreszenzquantumseffizienz von farbstoffen in lösungen
ATE419352T1 (de) Pigmentprotein
WO2003023375A3 (en) Toxicity monitoring
ATE506434T1 (de) Fluoreszenzprotein
JP4553895B2 (ja) 均質発光エネルギー伝達バイオアッセイ
DE69430500D1 (de) Chemilumineszierende Derivate mit langer Emissionswellenlänge und ihre Verwendung in Assays
Wang et al. Distance measurements in cardiac troponin C
JP3792899B2 (ja) 化学発光酵素免疫測定方法
Savitsky et al. Solid surface measurement of room temperature phosphorescence of Pd-coproporphyrin and its application for time-resolved microscopy

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1514112

Country of ref document: EP

REN Ceased due to non-payment of the annual fee