ATE509120T1 - Fusionsproteine zur detektion von analyten - Google Patents

Fusionsproteine zur detektion von analyten

Info

Publication number
ATE509120T1
ATE509120T1 AT02767487T AT02767487T ATE509120T1 AT E509120 T1 ATE509120 T1 AT E509120T1 AT 02767487 T AT02767487 T AT 02767487T AT 02767487 T AT02767487 T AT 02767487T AT E509120 T1 ATE509120 T1 AT E509120T1
Authority
AT
Austria
Prior art keywords
detection
portions
fusion proteins
protein
detecting analytes
Prior art date
Application number
AT02767487T
Other languages
English (en)
Inventor
Wolf-Bernd Frommer
Marcus Fehr
Sylvie Lalonde
Original Assignee
Carnegie Inst Of Washington
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Carnegie Inst Of Washington filed Critical Carnegie Inst Of Washington
Application granted granted Critical
Publication of ATE509120T1 publication Critical patent/ATE509120T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43595Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from coelenteratae, e.g. medusae
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/20Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/60Fusion polypeptide containing spectroscopic/fluorescent detection, e.g. green fluorescent protein [GFP]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
AT02767487T 2001-09-18 2002-09-13 Fusionsproteine zur detektion von analyten ATE509120T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP01122301 2001-09-18
EP02007373 2002-04-08
PCT/EP2002/010340 WO2003025220A2 (en) 2001-09-18 2002-09-13 Fusion proteins useful for detecting analytes

Publications (1)

Publication Number Publication Date
ATE509120T1 true ATE509120T1 (de) 2011-05-15

Family

ID=26076716

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02767487T ATE509120T1 (de) 2001-09-18 2002-09-13 Fusionsproteine zur detektion von analyten

Country Status (4)

Country Link
US (1) US20070136825A1 (de)
EP (2) EP1427856B1 (de)
AT (1) ATE509120T1 (de)
WO (1) WO2003025220A2 (de)

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EP2162057A1 (de) 2007-05-10 2010-03-17 Glumetrics, Inc. Verschleissbeständiger gleichgewichtsfluoreszenzsensor für intravaskuläre echtzeit-glukosemessung
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EP2217316A4 (de) 2007-11-21 2013-01-16 Glumetrics Inc Verwendung eines intravaskulären equilibrium-sensors für enge glykämische kontrolle
US8663632B1 (en) 2008-03-13 2014-03-04 University Of Kentucky Research Foundation Compositions and methods for selectively targeting cancer cells using a thiaminase compound
WO2010066113A1 (zh) * 2008-12-11 2010-06-17 国立大学法人东京大学 拆分荧光蛋白的融合蛋白组合、其表达载体,稳定表达哺乳动物细胞系及筛选方法
EP2483679A4 (de) 2009-09-30 2013-04-24 Glumetrics Inc Sensoren mit thrombenresistenter beschichtung
US8741591B2 (en) * 2009-10-09 2014-06-03 The Research Foundation For The State University Of New York pH-insensitive glucose indicator protein
US8467843B2 (en) 2009-11-04 2013-06-18 Glumetrics, Inc. Optical sensor configuration for ratiometric correction of blood glucose measurement
US8473222B2 (en) * 2010-03-11 2013-06-25 Glumetrics, Inc. Measurement devices and methods for measuring analyte concentration incorporating temperature and pH correction
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CN103299193B (zh) 2010-10-19 2016-08-10 佐治亚州立大学研究基金会公司 分析物传感器、制备和使用所述传感器的方法、以及检测分析物活性的方法
US9037205B2 (en) 2011-06-30 2015-05-19 Glusense, Ltd Implantable optical glucose sensing
JP6106264B2 (ja) * 2012-04-13 2017-03-29 セントロ デ エストゥディオス シエンティフィコス デ ヴァルディヴィアCentro De Estudios Cientificos De Valdivia 乳酸塩の定量のための遺伝学的にコードされたプローブならびに代謝速度および乳酸塩輸送の定量方法
US20170298402A1 (en) * 2014-10-03 2017-10-19 President And Fellows Of Harvard College Self-labeling nucleic acids and methods of use
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JP6535483B2 (ja) * 2015-03-02 2019-06-26 国立研究開発法人農業・食品産業技術総合研究機構 幼若ホルモンセンサー
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Also Published As

Publication number Publication date
EP2284195A9 (de) 2013-03-27
EP2284195A1 (de) 2011-02-16
US20070136825A1 (en) 2007-06-14
WO2003025220A2 (en) 2003-03-27
EP1427856A2 (de) 2004-06-16
EP1427856B1 (de) 2011-05-11
WO2003025220A3 (en) 2003-12-11

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