ATE509120T1 - Fusionsproteine zur detektion von analyten - Google Patents
Fusionsproteine zur detektion von analytenInfo
- Publication number
- ATE509120T1 ATE509120T1 AT02767487T AT02767487T ATE509120T1 AT E509120 T1 ATE509120 T1 AT E509120T1 AT 02767487 T AT02767487 T AT 02767487T AT 02767487 T AT02767487 T AT 02767487T AT E509120 T1 ATE509120 T1 AT E509120T1
- Authority
- AT
- Austria
- Prior art keywords
- detection
- portions
- fusion proteins
- protein
- detecting analytes
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43595—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from coelenteratae, e.g. medusae
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/60—Fusion polypeptide containing spectroscopic/fluorescent detection, e.g. green fluorescent protein [GFP]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Urology & Nephrology (AREA)
- Biophysics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01122301 | 2001-09-18 | ||
| EP02007373 | 2002-04-08 | ||
| PCT/EP2002/010340 WO2003025220A2 (en) | 2001-09-18 | 2002-09-13 | Fusion proteins useful for detecting analytes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE509120T1 true ATE509120T1 (de) | 2011-05-15 |
Family
ID=26076716
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02767487T ATE509120T1 (de) | 2001-09-18 | 2002-09-13 | Fusionsproteine zur detektion von analyten |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20070136825A1 (de) |
| EP (2) | EP1427856B1 (de) |
| AT (1) | ATE509120T1 (de) |
| WO (1) | WO2003025220A2 (de) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004033485A2 (en) | 2002-10-09 | 2004-04-22 | The Trustees Of Boston University | Nucleic acid supported protein complementation |
| US20050112685A1 (en) * | 2003-11-26 | 2005-05-26 | Amiss Terry J. | Compositions and methods for measuring analyte concentrations |
| KR20070040329A (ko) * | 2004-03-17 | 2007-04-16 | 유니버시티 오브 하와이 | 센서 구조물 및 검출방법 |
| US7951357B2 (en) | 2004-07-14 | 2011-05-31 | Glusense Ltd. | Implantable power sources and sensors |
| US8530633B2 (en) | 2004-10-14 | 2013-09-10 | Carnegie Institution Of Washington | Development of sensitive FRET sensors and methods of using the same |
| CA2584116A1 (en) | 2004-10-14 | 2006-04-27 | Carnegie Institution Of Washington | Neurotransmitter sensors and methods of using the same |
| JP5161588B2 (ja) * | 2005-03-04 | 2013-03-13 | カーネギー インスチチューション オブ ワシントン | 環境的に安定なセンサおよびそれを使用する方法 |
| KR100739529B1 (ko) * | 2005-07-25 | 2007-07-13 | 한국생명공학연구원 | 세포내 맥아당의 정량적 측정을 위한 맥아당 바이오센서 |
| DE602005025043D1 (de) | 2005-10-14 | 2011-01-05 | Carnegie Inst Of Washington | Saccharose-biosensoren und verwendungsverfahren dafür |
| AU2005337446A1 (en) * | 2005-10-14 | 2007-04-26 | Carnegie Institution Of Washington | Methods of reducing repeat-induced silencing of transgene expression and improved fluorescent biosensors |
| AU2005337168B2 (en) * | 2005-10-14 | 2012-07-05 | Carnegie Institution Of Washington | Phosphate biosensors and methods of using the same |
| US20090220942A1 (en) * | 2005-10-27 | 2009-09-03 | Natalia Broude | Activated split-polypeptides and methods for their production and use |
| US20120122115A1 (en) * | 2006-04-25 | 2012-05-17 | Sayre Richard T | Bacterial quorum sensing biosensor |
| CA2671431C (en) * | 2006-12-14 | 2019-03-26 | Georgia State University Research Foundation, Inc. | Analyte sensors, methods for preparing and using such sensors, and methods of detecting analyte activity |
| US8838195B2 (en) | 2007-02-06 | 2014-09-16 | Medtronic Minimed, Inc. | Optical systems and methods for ratiometric measurement of blood glucose concentration |
| EP2162057A1 (de) | 2007-05-10 | 2010-03-17 | Glumetrics, Inc. | Verschleissbeständiger gleichgewichtsfluoreszenzsensor für intravaskuläre echtzeit-glukosemessung |
| CN101855239B (zh) * | 2007-06-20 | 2013-11-06 | 巴斯夫欧洲公司 | 合成的重复蛋白及其生产和用途 |
| WO2009021052A1 (en) * | 2007-08-06 | 2009-02-12 | University Of Kentucky Research Foundation | Polypeptides, systems, and methods useful for detecting glucose |
| US20110229415A1 (en) * | 2007-08-06 | 2011-09-22 | Sylvia Daunert | Semi-synthetic antibodies as recognition elements |
| EP2181328A4 (de) * | 2007-08-10 | 2010-07-21 | Carnegie Inst Of Washington | Verfahren zur verwendung von ret-nanosensoren |
| AU2008293525A1 (en) * | 2007-08-29 | 2009-03-05 | Plant Sensory System, Llc. | Metabolic regulators |
| US8742204B2 (en) | 2007-08-29 | 2014-06-03 | Plant Sensory Systems, Llc | Metabolic regulators |
| ITTO20070687A1 (it) * | 2007-10-01 | 2009-04-02 | Consiglio Nazionale Ricerche | Nuovo mutante di gfp sensibile al ph e alla concentrazione di anioni, proteina chimerica comprendente tale mutante e procedimento di determinazione combinata del ph e della concentrazione di anioni |
| EP2203558B1 (de) * | 2007-10-18 | 2016-05-04 | Cell Signaling Technology, Inc. | Translokation und mutations-ros-kinase bei menschlichem nicht-kleinzelligem bronchialkarzinom |
| EP2217316A4 (de) | 2007-11-21 | 2013-01-16 | Glumetrics Inc | Verwendung eines intravaskulären equilibrium-sensors für enge glykämische kontrolle |
| US8663632B1 (en) | 2008-03-13 | 2014-03-04 | University Of Kentucky Research Foundation | Compositions and methods for selectively targeting cancer cells using a thiaminase compound |
| WO2010066113A1 (zh) * | 2008-12-11 | 2010-06-17 | 国立大学法人东京大学 | 拆分荧光蛋白的融合蛋白组合、其表达载体,稳定表达哺乳动物细胞系及筛选方法 |
| EP2483679A4 (de) | 2009-09-30 | 2013-04-24 | Glumetrics Inc | Sensoren mit thrombenresistenter beschichtung |
| US8741591B2 (en) * | 2009-10-09 | 2014-06-03 | The Research Foundation For The State University Of New York | pH-insensitive glucose indicator protein |
| US8467843B2 (en) | 2009-11-04 | 2013-06-18 | Glumetrics, Inc. | Optical sensor configuration for ratiometric correction of blood glucose measurement |
| US8473222B2 (en) * | 2010-03-11 | 2013-06-25 | Glumetrics, Inc. | Measurement devices and methods for measuring analyte concentration incorporating temperature and pH correction |
| US20120076736A1 (en) * | 2010-09-17 | 2012-03-29 | Rochester Institute Of Technology | Host supported genetic biosensors |
| CN103299193B (zh) | 2010-10-19 | 2016-08-10 | 佐治亚州立大学研究基金会公司 | 分析物传感器、制备和使用所述传感器的方法、以及检测分析物活性的方法 |
| US9037205B2 (en) | 2011-06-30 | 2015-05-19 | Glusense, Ltd | Implantable optical glucose sensing |
| JP6106264B2 (ja) * | 2012-04-13 | 2017-03-29 | セントロ デ エストゥディオス シエンティフィコス デ ヴァルディヴィアCentro De Estudios Cientificos De Valdivia | 乳酸塩の定量のための遺伝学的にコードされたプローブならびに代謝速度および乳酸塩輸送の定量方法 |
| US20170298402A1 (en) * | 2014-10-03 | 2017-10-19 | President And Fellows Of Harvard College | Self-labeling nucleic acids and methods of use |
| CN106999118B (zh) | 2014-10-13 | 2020-07-17 | 葡萄糖传感器公司 | 分析物感测装置 |
| JP6535483B2 (ja) * | 2015-03-02 | 2019-06-26 | 国立研究開発法人農業・食品産業技術総合研究機構 | 幼若ホルモンセンサー |
| EP3377643A4 (de) * | 2015-11-20 | 2019-10-02 | Duke University | Glucosebiosensor und verwendungen davon |
| US10871487B2 (en) | 2016-04-20 | 2020-12-22 | Glusense Ltd. | FRET-based glucose-detection molecules |
| KR20220115927A (ko) * | 2019-10-25 | 2022-08-19 | 세르카코르 래버러토리즈, 인크. | 지표 화합물, 지표 화합물을 포함하는 장치, 및 이의 제조 및 사용 방법 |
| US11331020B2 (en) | 2020-02-06 | 2022-05-17 | Trustees Of Boston University | Enzyme-based electrochemical nicotine biosensor |
| WO2021221752A2 (en) | 2020-02-06 | 2021-11-04 | Trustees Of Boston University | High throughput assay for identifying microbial redox enzymes |
| CA3180508A1 (en) | 2020-04-17 | 2021-10-21 | Regeneron Pharmaceuticals, Inc. | Detection assays for coronavirus neutralizing antibodies |
| CN117405502B (zh) * | 2023-12-12 | 2024-02-13 | 山东海奥斯生物科技股份有限公司 | 一种植物蛋白膜强度自动检测装置 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4711955A (en) | 1981-04-17 | 1987-12-08 | Yale University | Modified nucleotides and methods of preparing and using same |
| CA1223831A (en) | 1982-06-23 | 1987-07-07 | Dean Engelhardt | Modified nucleotides, methods of preparing and utilizing and compositions containing the same |
| ATE115999T1 (de) | 1987-12-15 | 1995-01-15 | Gene Shears Pty Ltd | Ribozyme. |
| US5034323A (en) | 1989-03-30 | 1991-07-23 | Dna Plant Technology Corporation | Genetic engineering of novel plant phenotypes |
| US5792608A (en) | 1991-12-12 | 1998-08-11 | Gilead Sciences, Inc. | Nuclease stable and binding competent oligomers and methods for their use |
| DE69321962T2 (de) | 1992-08-21 | 1999-07-01 | Biogen Inc | Von tat abgeleitete transportpolypeptide |
| PT733059E (pt) | 1993-12-09 | 2001-03-30 | Univ Jefferson | Compostos e metodos para mutacoes dirigidas ao local em celulas eucarioticas |
| US5525711A (en) | 1994-05-18 | 1996-06-11 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Pteridine nucleotide analogs as fluorescent DNA probes |
| EP0970199B1 (de) | 1997-03-14 | 2008-10-22 | The Regents Of The University Of California | Fluoreszenzprotein-sensoren zur erkennung von analyten |
| US5998204A (en) * | 1997-03-14 | 1999-12-07 | The Regents Of The University Of California | Fluorescent protein sensors for detection of analytes |
| AU4254299A (en) | 1998-06-16 | 2000-01-05 | Biosignal Packard Inc. | A bioluminescence resonance energy transfer (bret) system and its use |
| EP1098658B1 (de) * | 1998-07-17 | 2009-07-08 | University of Maryland, Baltimore | Manipulierte proteine zum analyten nachweis |
| WO2000034323A1 (en) | 1998-12-11 | 2000-06-15 | Clontech Laboratories, Inc. | Fluorescent proteins from non-bioluminescent species of class anthozoa, genes encoding such proteins and uses thereof |
| WO2000034321A1 (en) | 1998-12-11 | 2000-06-15 | Clontech Laboratories, Inc. | Fluorescent proteins from non-bioluminescent species of class anthozoa, genes encoding such proteins and uses thereof |
| WO2000034326A1 (en) | 1998-12-11 | 2000-06-15 | Clontech Laboratories, Inc. | Fluorescent proteins from non-bioluminescent species of class anthozoa, genes encoding such proteins and uses thereof |
| JP4618891B2 (ja) | 1998-12-11 | 2011-01-26 | クロンテック・ラボラトリーズ・インコーポレーテッド | Anthozoa綱の非生物発光性種由来の蛍光タンパク質、そのようなタンパク質をコードする遺伝子、およびそれらの使用 |
| WO2000034325A1 (en) | 1998-12-11 | 2000-06-15 | Clontech Laboratories, Inc. | Fluorescent proteins from non-bioluminescent species of class anthozoa, genes encoding such proteins and uses thereof |
| WO2000034324A1 (en) | 1998-12-11 | 2000-06-15 | Clontech Laboratories, Inc. | Fluorescent proteins from non-bioluminescent species of class anthozoa, genes encoding such proteins and uses thereof |
| WO2000034322A1 (en) | 1998-12-11 | 2000-06-15 | Clontech Laboratories, Inc. | Fluorescent proteins from non-bioluminescent species of class anthozoa, genes encoding such proteins and uses thereof |
| WO2000049183A1 (en) * | 1999-02-17 | 2000-08-24 | Clontech Laboratories, Inc. | FLUORESCENCE RESONANCE ENERGY TRANSFER DETECTION OF cAMP IN LIVING CELLS USING GFP VARIANTS |
| US7109315B2 (en) * | 2000-03-15 | 2006-09-19 | Bruce J. Bryan | Renilla reniformis fluorescent proteins, nucleic acids encoding the fluorescent proteins and the use thereof in diagnostics, high throughput screening and novelty items |
| KR100739529B1 (ko) * | 2005-07-25 | 2007-07-13 | 한국생명공학연구원 | 세포내 맥아당의 정량적 측정을 위한 맥아당 바이오센서 |
-
2002
- 2002-09-13 EP EP02767487A patent/EP1427856B1/de not_active Expired - Lifetime
- 2002-09-13 US US10/490,153 patent/US20070136825A1/en not_active Abandoned
- 2002-09-13 WO PCT/EP2002/010340 patent/WO2003025220A2/en not_active Ceased
- 2002-09-13 AT AT02767487T patent/ATE509120T1/de not_active IP Right Cessation
- 2002-09-13 EP EP10182215A patent/EP2284195A1/de not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP2284195A9 (de) | 2013-03-27 |
| EP2284195A1 (de) | 2011-02-16 |
| US20070136825A1 (en) | 2007-06-14 |
| WO2003025220A2 (en) | 2003-03-27 |
| EP1427856A2 (de) | 2004-06-16 |
| EP1427856B1 (de) | 2011-05-11 |
| WO2003025220A3 (en) | 2003-12-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |