ATE339186T1 - Methode zur herstellung von mikropartikeln enthaltend biologisches material - Google Patents

Methode zur herstellung von mikropartikeln enthaltend biologisches material

Info

Publication number
ATE339186T1
ATE339186T1 AT00945895T AT00945895T ATE339186T1 AT E339186 T1 ATE339186 T1 AT E339186T1 AT 00945895 T AT00945895 T AT 00945895T AT 00945895 T AT00945895 T AT 00945895T AT E339186 T1 ATE339186 T1 AT E339186T1
Authority
AT
Austria
Prior art keywords
biological material
containing biological
microparticles containing
producing microparticles
producing
Prior art date
Application number
AT00945895T
Other languages
English (en)
Inventor
Arnold Hilgers
Original Assignee
Arnold Hilgers
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arnold Hilgers filed Critical Arnold Hilgers
Application granted granted Critical
Publication of ATE339186T1 publication Critical patent/ATE339186T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/113—Multiple emulsions, e.g. oil-in-water-in-oil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
AT00945895T 1999-07-08 2000-07-07 Methode zur herstellung von mikropartikeln enthaltend biologisches material ATE339186T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99113251 1999-07-08
EP00101030A EP1074248A1 (de) 1999-07-08 2000-01-20 Verabreichungssystem für biologisches Material

Publications (1)

Publication Number Publication Date
ATE339186T1 true ATE339186T1 (de) 2006-10-15

Family

ID=26070448

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00945895T ATE339186T1 (de) 1999-07-08 2000-07-07 Methode zur herstellung von mikropartikeln enthaltend biologisches material

Country Status (8)

Country Link
US (1) US7008643B1 (de)
EP (2) EP1074248A1 (de)
JP (1) JP4988114B2 (de)
AT (1) ATE339186T1 (de)
AU (1) AU770296B2 (de)
CA (1) CA2375549C (de)
DE (1) DE60030726T2 (de)
WO (1) WO2001003667A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1456377T (pt) * 2001-12-20 2019-09-10 Merck Sharp & Dohme Composições de syn3 e processos
US20060105018A1 (en) * 2004-11-17 2006-05-18 Epstein Samuel J Therapeutic driving layer for a medical device
SE529040C2 (sv) * 2006-01-18 2007-04-17 Bows Pharmaceuticals Ag Förfarande för framställning av en dextranmatris för kontrollerad frisättning av insulin
WO2007109725A2 (en) 2006-03-21 2007-09-27 Three Point Optics, Inc. Active mask variable data integral imaging system and method
EP2089554B1 (de) 2006-11-14 2013-06-05 Aleris Aluminum Duffel BVBA Mehrschichtige Rohre enthaltend eine kriechfeste Aluminiumlegierung
FR2928373B1 (fr) 2008-03-05 2010-12-31 Centre Nat Rech Scient Polymere derive de la polyethylenimine lineaire pour le transfert de gene.

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4181589A (en) 1979-03-06 1980-01-01 Nasa Method for separating biological cells
US4849355A (en) 1985-01-08 1989-07-18 Wong Tai Kin Method of transferring genes into cells
SE459005B (sv) * 1985-07-12 1989-05-29 Aake Rikard Lindahl Saett att framstaella sfaeriska polymerpartiklar
US5985354A (en) * 1995-06-07 1999-11-16 Brown University Research Foundation Preparation of multiwall polymeric microcapsules from hydrophilic polymers
FR2651680B1 (fr) * 1989-09-14 1991-12-27 Medgenix Group Sa Nouveau procede de preparation de microparticules lipidiques.
US5478564A (en) * 1990-02-22 1995-12-26 Teva Pharmaceutical Industries, Ltd. Preparation of microparticles for controlled release of water-soluble substances
CA2019758C (en) 1990-06-25 2001-09-04 Kevin L. Firth Improved electroporation device and method
FR2694895B1 (fr) * 1992-08-20 1994-11-10 Coletica Procédé de fabrication de microparticules en émulsion par modification de la composition chimique de la phase dispersée après émulsification.
ES2113094T3 (es) * 1993-03-09 1998-04-16 Epic Therapeutics Inc Las microparticulas macromoleculares y metodos de obtencion.
CA2159804A1 (en) * 1993-04-08 1994-10-27 Human Cell Cultures, Inc. Cell culturing method and medium
US6051256A (en) * 1994-03-07 2000-04-18 Inhale Therapeutic Systems Dispersible macromolecule compositions and methods for their preparation and use
EP0804249A2 (de) * 1994-03-15 1997-11-05 Brown University Research Foundation Polymeres system zur freisetzung von genen
US5789213A (en) * 1995-05-11 1998-08-04 Health Research Inc. Method and compositions for high efficiency loading, transfection and fusion of cells by electric pulses
US6143211A (en) * 1995-07-21 2000-11-07 Brown University Foundation Process for preparing microparticles through phase inversion phenomena
US5942253A (en) * 1995-10-12 1999-08-24 Immunex Corporation Prolonged release of GM-CSF
US5817343A (en) * 1996-05-14 1998-10-06 Alkermes, Inc. Method for fabricating polymer-based controlled-release devices
US6395302B1 (en) * 1996-11-19 2002-05-28 Octoplus B.V. Method for the preparation of microspheres which contain colloidal systems
EP0842657A1 (de) * 1996-11-19 1998-05-20 OctoPlus B.V. Mikrosphären zur gesteuerten Freisetzung und Verfahren zur Herstellung dieser Mikrosphären
US5989463A (en) * 1997-09-24 1999-11-23 Alkermes Controlled Therapeutics, Inc. Methods for fabricating polymer-based controlled release devices
US6224794B1 (en) * 1998-05-06 2001-05-01 Angiotech Pharmaceuticals, Inc. Methods for microsphere production
US6291013B1 (en) * 1999-05-03 2001-09-18 Southern Biosystems, Inc. Emulsion-based processes for making microparticles

Also Published As

Publication number Publication date
CA2375549C (en) 2008-11-25
EP1074248A1 (de) 2001-02-07
US7008643B1 (en) 2006-03-07
EP1200067B1 (de) 2006-09-13
JP2003504320A (ja) 2003-02-04
DE60030726D1 (de) 2006-10-26
CA2375549A1 (en) 2001-01-18
AU770296B2 (en) 2004-02-19
WO2001003667A1 (en) 2001-01-18
EP1200067A1 (de) 2002-05-02
DE60030726T2 (de) 2007-09-13
JP4988114B2 (ja) 2012-08-01
AU5983300A (en) 2001-01-30

Similar Documents

Publication Publication Date Title
DE69717519D1 (de) Verfahren zur Herstellung von biologischem Implantationsmaterial
WO1999020766A3 (en) NOVEL MODIFIED NUCLEIC ACID SEQUENCES AND METHODS FOR INCREASING mRNA LEVELS AND PROTEIN EXPRESSION IN CELL SYSTEMS
DE69929310D1 (de) Tumorassoziierte antigenderivate der mage-familie, nukleinsäuresequenzen die dafür kodieren, zur herstellung von fusionsproteinen und zusammensetzungen zur impfung
DE69635609D1 (de) Nukleinsäure enthaltende zusammensetzung, herstellung und verwendung
WO1999064592A3 (en) Green fluorescent proteins for measuring the ph of a biological sample
ATE535615T1 (de) Chemisch modifizierte nukleinsäuren und methode zur kopplung von nukleinsäuren an einen festen träger
DE69121618D1 (de) Mutierte Luciferase vom Leuchtkäfer, mutiertes Luciferasegen, rekombinante DNS diese Gene enthaltend, und Verfahren zur Herstellung von mutierter Luciferase
DE60017336D1 (de) Zusammensetzung zur Herstellung von Harzen
DE60001600D1 (de) Methode zur Herstellung von vertikalen Transistoren
DE60002793D1 (de) Verfahren zur Herstellung von Acrolein und Acrylsäure
DE69935978D1 (de) Kulturmedium zur kultivierung tierischer zellen und verfahren zur herstellung von proteinen durch dessen verwendung
AU6160201A (en) Human polypeptides causing or leading to the killing of cells including lymphoidtumor cells
WO1999047661A3 (en) Production of biofilaments in transgenic animals
DE60222644D1 (de) Prozess zur herstellung von transparenten formteilen
DE60017237D1 (de) Verfahren zur mikrobiellen Herstellung von Polyestern
DE50005837D1 (de) Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung coryneformer Bakterien
DE60030726D1 (de) Methode zur Herstellung von Mikropartikeln enthaltend biologisches Material
DE60205955D1 (de) Verfahren zur Herstellung von L-Aminosäuren
DE60020048D1 (de) Verfahren zur Herstellung von Methacrylsäure
BR0001342A (pt) Processo para a produção de l-aminoácidos por meio de fermentação usando bactérias corineformes
DE60220621D1 (de) Posh Nukleinsäure, Polypeptide und darauf bezogene Verfahren
DE60136558D1 (de) Verfahren zur kultivierung humaner chondrozyten
DE69708682D1 (de) Methode zur herstellung von zusammengesetztem keramischen material
BR0008187A (pt) Controle biológico de nematódeos
DE60010034D1 (de) Methode zur handhabung von 1,1,1,3,3-pentfluoropropan

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1200067

Country of ref document: EP