ATE339507T1 - Erythropoietin-analog-menschliches serum-albumin fusionsprotein - Google Patents

Erythropoietin-analog-menschliches serum-albumin fusionsprotein

Info

Publication number
ATE339507T1
ATE339507T1 AT99928656T AT99928656T ATE339507T1 AT E339507 T1 ATE339507 T1 AT E339507T1 AT 99928656 T AT99928656 T AT 99928656T AT 99928656 T AT99928656 T AT 99928656T AT E339507 T1 ATE339507 T1 AT E339507T1
Authority
AT
Austria
Prior art keywords
fusion protein
human serum
albumin fusion
erythropoietin analog
analog human
Prior art date
Application number
AT99928656T
Other languages
English (en)
Inventor
Michael W Young
Harry M Meade
Ian M Krane
Original Assignee
Gtc Biotherapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gtc Biotherapeutics Inc filed Critical Gtc Biotherapeutics Inc
Application granted granted Critical
Publication of ATE339507T1 publication Critical patent/ATE339507T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/505—Erythropoietin [EPO]
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT99928656T 1998-06-15 1999-06-15 Erythropoietin-analog-menschliches serum-albumin fusionsprotein ATE339507T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8934398P 1998-06-15 1998-06-15

Publications (1)

Publication Number Publication Date
ATE339507T1 true ATE339507T1 (de) 2006-10-15

Family

ID=22217149

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99928656T ATE339507T1 (de) 1998-06-15 1999-06-15 Erythropoietin-analog-menschliches serum-albumin fusionsprotein

Country Status (10)

Country Link
US (4) US6548653B1 (de)
EP (1) EP1088084B1 (de)
JP (1) JP4087563B2 (de)
AT (1) ATE339507T1 (de)
AU (1) AU775422B2 (de)
CA (1) CA2330527A1 (de)
DE (1) DE69933216T2 (de)
DK (1) DK1088084T3 (de)
ES (1) ES2273497T3 (de)
WO (1) WO1999066054A2 (de)

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US20040143857A1 (en) 2004-07-22
JP2002518018A (ja) 2002-06-25
DE69933216T2 (de) 2007-09-20
WO1999066054A2 (en) 1999-12-23
AU775422B2 (en) 2004-07-29
WO1999066054A3 (en) 2000-04-06
HK1036475A1 (en) 2002-01-04
ES2273497T3 (es) 2007-05-01
US7101971B2 (en) 2006-09-05
DE69933216D1 (de) 2006-10-26
AU4566899A (en) 2000-01-05
US20020155998A1 (en) 2002-10-24
US6548653B1 (en) 2003-04-15
US20050158832A1 (en) 2005-07-21
DK1088084T3 (da) 2007-01-29
JP4087563B2 (ja) 2008-05-21
EP1088084A2 (de) 2001-04-04
CA2330527A1 (en) 1999-12-23
EP1088084B1 (de) 2006-09-13

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