ATE340580T1 - Verwendung von zusammensetzungen enthaltend ein oestrogen zur behandlung und verhinderung von muskelskelettschmerzen - Google Patents
Verwendung von zusammensetzungen enthaltend ein oestrogen zur behandlung und verhinderung von muskelskelettschmerzenInfo
- Publication number
- ATE340580T1 ATE340580T1 AT04734005T AT04734005T ATE340580T1 AT E340580 T1 ATE340580 T1 AT E340580T1 AT 04734005 T AT04734005 T AT 04734005T AT 04734005 T AT04734005 T AT 04734005T AT E340580 T1 ATE340580 T1 AT E340580T1
- Authority
- AT
- Austria
- Prior art keywords
- sub
- group
- estrogen
- inhibitors
- formula
- Prior art date
Links
- 239000000262 estrogen Substances 0.000 title abstract 2
- 229940011871 estrogen Drugs 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 230000002265 prevention Effects 0.000 title 1
- 239000000126 substance Substances 0.000 abstract 3
- 102000010907 Cyclooxygenase 2 Human genes 0.000 abstract 2
- 108010037462 Cyclooxygenase 2 Proteins 0.000 abstract 2
- 230000001076 estrogenic effect Effects 0.000 abstract 2
- 239000003112 inhibitor Substances 0.000 abstract 2
- 239000002243 precursor Substances 0.000 abstract 2
- 102100037426 17-beta-hydroxysteroid dehydrogenase type 1 Human genes 0.000 abstract 1
- 101710147298 17-beta-hydroxysteroid dehydrogenase type 1 Proteins 0.000 abstract 1
- 101710174215 Estradiol 17-beta-dehydrogenase 1 Proteins 0.000 abstract 1
- NMJREATYWWNIKX-UHFFFAOYSA-N GnRH Chemical class C1CCC(C(=O)NCC(N)=O)N1C(=O)C(CC(C)C)NC(=O)C(CC=1C2=CC=CC=C2NC=1)NC(=O)CNC(=O)C(NC(=O)C(CO)NC(=O)C(CC=1C2=CC=CC=C2NC=1)NC(=O)C(CC=1NC=NC=1)NC(=O)C1NC(=O)CC1)CC1=CC=C(O)C=C1 NMJREATYWWNIKX-UHFFFAOYSA-N 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 206010028391 Musculoskeletal Pain Diseases 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 229940046836 anti-estrogen Drugs 0.000 abstract 1
- 230000001833 anti-estrogenic effect Effects 0.000 abstract 1
- 239000003886 aromatase inhibitor Substances 0.000 abstract 1
- 229940046844 aromatase inhibitors Drugs 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000000328 estrogen antagonist Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000000583 progesterone congener Substances 0.000 abstract 1
- 229940095055 progestogen systemic hormonal contraceptives Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physical Education & Sports Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03076555 | 2003-05-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE340580T1 true ATE340580T1 (de) | 2006-10-15 |
Family
ID=33462160
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04734005T ATE340580T1 (de) | 2003-05-22 | 2004-05-19 | Verwendung von zusammensetzungen enthaltend ein oestrogen zur behandlung und verhinderung von muskelskelettschmerzen |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20060276414A1 (de) |
| EP (1) | EP1624878B1 (de) |
| CN (1) | CN100431545C (de) |
| AT (1) | ATE340580T1 (de) |
| CA (1) | CA2526338C (de) |
| CY (1) | CY1105766T1 (de) |
| DE (1) | DE602004002591T9 (de) |
| DK (1) | DK1624878T3 (de) |
| ES (1) | ES2274456T3 (de) |
| PL (1) | PL1624878T3 (de) |
| PT (1) | PT1624878E (de) |
| SI (1) | SI1624878T1 (de) |
| WO (1) | WO2004103377A1 (de) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1526856B1 (de) | 2002-07-12 | 2008-01-02 | Pantarhei Bioscience B.V. | Pharmazeutische zusammensetzung enthaltend estetrolderivate und anwendung in der krebsbehandlung |
| US20080287408A1 (en) * | 2007-05-14 | 2008-11-20 | Drugtech Corporation | Endometriosis treatment |
| CA2698814A1 (en) * | 2007-09-17 | 2009-03-26 | Preglem S.A. | Treatment of oestrogen dependant conditions in pre-menopausal women |
| CN103703014A (zh) | 2011-06-01 | 2014-04-02 | 埃斯特拉公司 | 用于产生雌四醇中间体的方法 |
| EA025511B1 (ru) | 2011-06-01 | 2016-12-30 | Эстетра С.П.Р.Л. | Способ получения промежуточных соединений эстетрола |
| EP2383279A1 (de) | 2011-07-19 | 2011-11-02 | Pantarhei Bioscience B.V. | Herstellungsverfahren für Esterol |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US8633178B2 (en) | 2011-11-23 | 2014-01-21 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| CA2947767A1 (en) | 2014-05-22 | 2015-11-26 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| LT3701944T (lt) | 2015-06-18 | 2022-04-11 | Estetra Srl | Burnoje disperguojamas dozavimo vienetas, kurio sudėtyje yra estetrolio komponentas |
| JP6813150B2 (ja) | 2015-06-18 | 2021-01-13 | エステトラ ソシエテ プリーヴ ア レスポンサビリテ リミテ | エステトロールを含有する口腔内崩壊錠 |
| ES2671160T3 (es) | 2015-06-18 | 2018-06-05 | Mithra Pharmaceuticals S.A. | Unidad de dosificación orodispersable que contiene un componente estetrol |
| PL3310345T3 (pl) * | 2015-06-18 | 2021-10-18 | Estetra Sprl | Ulegająca rozpadowi w jamie ustnej tabletka zawierająca estetrol |
| US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
| US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
| WO2017173071A1 (en) | 2016-04-01 | 2017-10-05 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical composition |
| KR102712911B1 (ko) | 2016-08-05 | 2024-10-04 | 에스테트라, 소시에떼 아 레스폰서빌리떼 리미떼 | 월경통 및 생리통의 관리방법 |
| SG11202009725XA (en) | 2018-04-19 | 2020-11-27 | Estetra Sprl | Compounds and their uses for alleviating menopause-associated symptoms |
| TWI801561B (zh) | 2018-04-19 | 2023-05-11 | 比利時商依思特拉私人有限責任公司 | 化合物及其用於緩解絕經相關症狀的用途 |
| CA3098601A1 (en) * | 2018-05-02 | 2019-11-07 | Estetra Sprl | Treatment of advanced estrogen receptor positive breast cancer |
| TWI893101B (zh) | 2020-04-16 | 2025-08-11 | 比利時商埃斯特拉有限責任公司 | 具有降低之副作用之避孕組成物 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2834712A (en) * | 1953-05-27 | 1958-05-13 | American Home Prod | Urinary estrogen compositions and methods for preparing them |
| US2753290A (en) * | 1953-08-06 | 1956-07-03 | Olin Mathieson | Microbiological production of 7-and 15-hydroxy-progesterones |
| US3440320A (en) * | 1964-06-18 | 1969-04-22 | Mortimer D Sackler | Chelated suppository and method of using same |
| US3487152A (en) * | 1967-02-07 | 1969-12-30 | Hoffmann La Roche | Tablets containing 7 - chloro - 2 - methylamino - 5 - phenyl - 3h - 1,4 - benzodiazepine-4-oxide and conjugated estrogenic substances |
| US3608075A (en) * | 1969-07-28 | 1971-09-21 | American Home Prod | Compositions and methods of treating the menopausal syndrome |
| YU243975A (en) * | 1974-10-14 | 1982-06-30 | Schering Ag | Process for obtaining 7-hydroxyestradiols |
| FR2377419A1 (fr) * | 1977-01-13 | 1978-08-11 | Roussel Uclaf | Nouveaux derives steroides 11b-substitues 1,3,5 (10) trieniques, leur procede de preparation et leur application comme medicament |
| US4937238A (en) * | 1986-03-04 | 1990-06-26 | The Board Of Regents Of The University Of Nebraska | Prevention of mammary carcinoma |
| US4762717A (en) * | 1986-03-21 | 1988-08-09 | The General Hospital Corporation | Continuous delivery of luteinizing hormone releasing hormone compositions in combination with sex steroid delivery for use as a contraceptive |
| US5340586A (en) * | 1991-04-12 | 1994-08-23 | University Of Southern California | Methods and formulations for use in treating oophorectomized women |
| US5211952A (en) * | 1991-04-12 | 1993-05-18 | University Of Southern California | Contraceptive methods and formulations for use therein |
| US5340585A (en) * | 1991-04-12 | 1994-08-23 | University Of Southern California | Method and formulations for use in treating benign gynecological disorders |
| US5270172A (en) * | 1991-04-26 | 1993-12-14 | Dekk-Tek, Inc. | Method to predict tumor response to therapy |
| US5468736A (en) * | 1993-02-25 | 1995-11-21 | The Medical College Of Hampton Road | Hormone replacement therapy |
| US5811416A (en) * | 1994-06-06 | 1998-09-22 | Board Of Regents The University Of Texas System | Endothelin antagonist and/or endothelin synthase inhibitor in combination with a progestin, an estrogen, a cyclooxygenase inhibitor, or a nitric acid donor or substrate |
| US6613757B1 (en) * | 1994-09-22 | 2003-09-02 | Board Of Regents, The University Of Texas System | Combination of prostacyclin with an estrogen or progestin for the prevention and treatment of atherosclerotic vascular disease including preeclampsia and for the treatment of hypertension, and for hormone replacement therapy |
| US5672609A (en) * | 1996-07-18 | 1997-09-30 | Eli Lilly And Company | Pyridine compounds, intermediates compositions and methods of use |
| US6170058B1 (en) * | 1997-12-23 | 2001-01-02 | Arcot Systems, Inc. | Method and apparatus for cryptographically camouflaged cryptographic key storage, certification and use |
| US20010056068A1 (en) * | 1998-03-04 | 2001-12-27 | Kristof Chwalisz | Method of treatment and prevention of nitric oxide deficiency-related disorders with citrulline and citrulline derivatives |
| US6291456B1 (en) * | 1998-12-30 | 2001-09-18 | Signal Pharmaceuticals, Inc. | Compounds and methods for modulation of estrogen receptors |
| US6117446A (en) * | 1999-01-26 | 2000-09-12 | Place; Virgil A. | Drug dosage unit for buccal administration of steroidal active agents |
| GB0005257D0 (en) * | 2000-03-03 | 2000-04-26 | Pharmacia & Upjohn Spa | Breast cancer hormonal therapy |
| RU2180570C1 (ru) * | 2000-09-25 | 2002-03-20 | Писаревский Юрий Леонидович | Способ лечения болевого синдрома при дисфункциях височно-нижнечелюстного сустава у женщин |
| US6790979B2 (en) * | 2002-04-17 | 2004-09-14 | University Of North Carolina At Chapel Hill | Curcumin analogues and uses thereof |
-
2004
- 2004-05-19 AT AT04734005T patent/ATE340580T1/de active
- 2004-05-19 DE DE602004002591T patent/DE602004002591T9/de active Active
- 2004-05-19 DK DK04734005T patent/DK1624878T3/da active
- 2004-05-19 PT PT04734005T patent/PT1624878E/pt unknown
- 2004-05-19 WO PCT/NL2004/000354 patent/WO2004103377A1/en not_active Ceased
- 2004-05-19 SI SI200430120T patent/SI1624878T1/sl unknown
- 2004-05-19 CA CA2526338A patent/CA2526338C/en not_active Expired - Lifetime
- 2004-05-19 PL PL04734005T patent/PL1624878T3/pl unknown
- 2004-05-19 EP EP04734005A patent/EP1624878B1/de not_active Expired - Lifetime
- 2004-05-19 CN CNB2004800177699A patent/CN100431545C/zh not_active Expired - Lifetime
- 2004-05-19 ES ES04734005T patent/ES2274456T3/es not_active Expired - Lifetime
- 2004-05-19 US US10/557,549 patent/US20060276414A1/en not_active Abandoned
-
2006
- 2006-11-08 CY CY20061101608T patent/CY1105766T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1816340A (zh) | 2006-08-09 |
| PL1624878T3 (pl) | 2007-01-31 |
| EP1624878B1 (de) | 2006-09-27 |
| ES2274456T3 (es) | 2007-05-16 |
| CN100431545C (zh) | 2008-11-12 |
| US20060276414A1 (en) | 2006-12-07 |
| CA2526338A1 (en) | 2004-12-02 |
| DE602004002591T2 (de) | 2007-08-09 |
| EP1624878A1 (de) | 2006-02-15 |
| CA2526338C (en) | 2012-09-25 |
| PT1624878E (pt) | 2007-01-31 |
| DE602004002591D1 (de) | 2006-11-09 |
| WO2004103377A1 (en) | 2004-12-02 |
| DE602004002591T9 (de) | 2008-01-03 |
| CY1105766T1 (el) | 2011-02-02 |
| SI1624878T1 (sl) | 2007-02-28 |
| DK1624878T3 (da) | 2007-01-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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