ATE340788T1 - Herstellung von stereoisomeren von (3alpha, 3alpha/beta, 6alpha/beta)hexahydrofuro(2,3- böfuran-3-ol - Google Patents

Herstellung von stereoisomeren von (3alpha, 3alpha/beta, 6alpha/beta)hexahydrofuro(2,3- böfuran-3-ol

Info

Publication number
ATE340788T1
ATE340788T1 AT03762054T AT03762054T ATE340788T1 AT E340788 T1 ATE340788 T1 AT E340788T1 AT 03762054 T AT03762054 T AT 03762054T AT 03762054 T AT03762054 T AT 03762054T AT E340788 T1 ATE340788 T1 AT E340788T1
Authority
AT
Austria
Prior art keywords
3alpha
beta
preparation
hexahydrofuro
böfuran
Prior art date
Application number
AT03762054T
Other languages
English (en)
Inventor
Brian Daniel Doan
Daniel Edward Patterson
John C Roberts
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Application granted granted Critical
Publication of ATE340788T1 publication Critical patent/ATE340788T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Seasonings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Developing Agents For Electrophotography (AREA)
AT03762054T 2002-06-27 2003-06-25 Herstellung von stereoisomeren von (3alpha, 3alpha/beta, 6alpha/beta)hexahydrofuro(2,3- böfuran-3-ol ATE340788T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US39267702P 2002-06-27 2002-06-27

Publications (1)

Publication Number Publication Date
ATE340788T1 true ATE340788T1 (de) 2006-10-15

Family

ID=30000917

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03762054T ATE340788T1 (de) 2002-06-27 2003-06-25 Herstellung von stereoisomeren von (3alpha, 3alpha/beta, 6alpha/beta)hexahydrofuro(2,3- böfuran-3-ol

Country Status (12)

Country Link
US (1) US20050261507A1 (de)
EP (1) EP1532127B1 (de)
JP (1) JP2005533821A (de)
AT (1) ATE340788T1 (de)
AU (1) AU2003247651A1 (de)
CY (1) CY1105856T1 (de)
DE (1) DE60308695T2 (de)
DK (1) DK1532127T3 (de)
ES (1) ES2268427T3 (de)
PT (1) PT1532127E (de)
SI (1) SI1532127T1 (de)
WO (1) WO2004002975A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1589018A4 (de) 2002-12-27 2007-03-14 Sumitomo Chemical Co Herstellungsverfahren für hexahydrofurofuranol-derivate, zwischenprodukt davon und herstellungsverfahren dafür
CN102432621B (zh) * 2006-11-09 2016-02-17 爱尔兰詹森科学公司 六氢呋喃并[2,3-b]呋喃-3-醇的制备方法
US8592487B2 (en) 2007-10-26 2013-11-26 Concert Pharmaceuticals, Inc. Deuterated darunavir
EP2217548A1 (de) * 2007-10-26 2010-08-18 Concert Pharmaceuticals Inc. Deuteriertes darunavir
WO2010075887A1 (en) * 2008-12-30 2010-07-08 Oxyrane (Uk) Limited Methods and intermediates useful in the synthesis of hexahydrofuro[2,3-b]furan-3-ol
WO2010127272A2 (en) * 2009-04-30 2010-11-04 Concert Pharmaceuticals, Inc. Hydroxyethylamino sulfonamide derivatives
US8841467B2 (en) 2010-11-23 2014-09-23 Mylan Laboratories Limited Process for the preparation of (3R, 3aS, 6aR)-hexahydrofuro [2, 3-b] furan-3-ol
EP2634180A1 (de) 2012-03-01 2013-09-04 Lonza Ltd. Enzymatisches Verfahren zur Herstellung von Butyrolactonen
JPWO2014024898A1 (ja) 2012-08-09 2016-07-25 住友化学株式会社 ヘキサヒドロフロフラノール誘導体の製造方法
CN103864813B (zh) * 2012-12-18 2017-02-22 上海迪赛诺化学制药有限公司 一种合成六氢呋喃并[2,3‑b]呋喃‑3‑醇及其对映体的方法
WO2017041228A1 (zh) * 2015-09-08 2017-03-16 浙江九洲药业股份有限公司 六氢呋喃并呋喃醇衍生物的制备方法、其中间体及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002255473A1 (en) * 2000-10-24 2002-09-04 Glaxo Group Limited Process for preparing intermediates of hiv protease inhibitors
AP1758A (en) * 2001-09-10 2007-07-30 Tibotec Pharm Ltd Method for the preparation of hexahydro-furo [2,3-b]furan-3-ol.
DE60213874T2 (de) * 2001-09-20 2007-10-18 Smithkline Beecham Corp. Verfahren zur herstellung von protease hemmenden zwischenprodukten

Also Published As

Publication number Publication date
DK1532127T3 (da) 2007-02-05
CY1105856T1 (el) 2011-02-02
ES2268427T3 (es) 2007-03-16
SI1532127T1 (sl) 2006-12-31
AU2003247651A1 (en) 2004-01-19
WO2004002975A1 (en) 2004-01-08
JP2005533821A (ja) 2005-11-10
DE60308695D1 (de) 2006-11-09
EP1532127A1 (de) 2005-05-25
EP1532127B1 (de) 2006-09-27
PT1532127E (pt) 2007-01-31
US20050261507A1 (en) 2005-11-24
DE60308695T2 (de) 2007-08-16

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