ATE342112T1 - Reinigung von biologischen substanzen - Google Patents

Reinigung von biologischen substanzen

Info

Publication number
ATE342112T1
ATE342112T1 AT00908806T AT00908806T ATE342112T1 AT E342112 T1 ATE342112 T1 AT E342112T1 AT 00908806 T AT00908806 T AT 00908806T AT 00908806 T AT00908806 T AT 00908806T AT E342112 T1 ATE342112 T1 AT E342112T1
Authority
AT
Austria
Prior art keywords
purification
biological substances
purifying
employing
types
Prior art date
Application number
AT00908806T
Other languages
English (en)
Inventor
Henry Kopf
Original Assignee
Ncsrt Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/255,186 external-priority patent/US6214221B1/en
Application filed by Ncsrt Inc filed Critical Ncsrt Inc
Application granted granted Critical
Publication of ATE342112T1 publication Critical patent/ATE342112T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B01D15/361—Ion-exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804—Affinity chromatography
    • B01D15/3809—Affinity chromatography of the antigen-antibody type, e.g. protein A, G or L chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Water Supply & Treatment (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Peptides Or Proteins (AREA)
  • Jellies, Jams, And Syrups (AREA)
AT00908806T 1999-02-22 2000-02-22 Reinigung von biologischen substanzen ATE342112T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/255,186 US6214221B1 (en) 1999-02-22 1999-02-22 Method and apparatus for purification of biological substances
US09/300,891 US6139746A (en) 1999-02-22 1999-04-28 Method and apparatus for purification of biological substances

Publications (1)

Publication Number Publication Date
ATE342112T1 true ATE342112T1 (de) 2006-11-15

Family

ID=26944506

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00908806T ATE342112T1 (de) 1999-02-22 2000-02-22 Reinigung von biologischen substanzen

Country Status (10)

Country Link
US (1) US6383380B1 (de)
EP (1) EP1154827B1 (de)
AT (1) ATE342112T1 (de)
AU (1) AU756832B2 (de)
CA (1) CA2361545C (de)
DE (1) DE60031244T2 (de)
DK (1) DK1154827T3 (de)
IL (1) IL144421A (de)
NZ (1) NZ513242A (de)
WO (1) WO2000048703A1 (de)

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US6214221B1 (en) * 1999-02-22 2001-04-10 Henry B. Kopf Method and apparatus for purification of biological substances
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KR100473703B1 (ko) * 2002-08-23 2005-03-10 한미약품 주식회사 형질전환 동물의 젖으로부터 재조합 펩타이드 또는단백질의 정제 방법
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BRPI0514435B8 (pt) 2004-08-20 2021-05-25 American Nat Red Cross isolamento sequêncial de proteínas e esquemas de purificação através de cromatografia por afinidade
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KR20100111097A (ko) * 2009-04-06 2010-10-14 삼성전자주식회사 표적물질 분리를 위한 미세유동장치 및 그 정제방법
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JP5860887B2 (ja) * 2010-10-15 2016-02-16 ジーイー・ヘルスケア・バイオサイエンス・コーポレイション 大容量使い捨て限外濾過システム及び方法
US8919385B2 (en) 2010-11-24 2014-12-30 Pall Corporation Manifold plates and fluid treatment arrangements including manifold plates
CA2864889C (en) 2011-02-21 2022-05-03 Smartflow Technologies, Inc. Method and systems for isolation and/or separation of ethanol from hydrocarbon-containing material
US10005697B1 (en) 2011-02-21 2018-06-26 Smartflow Technologies, Inc. Method and systems for isolation and/or separation of target products from animal produced waste streams
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US9284346B2 (en) * 2011-09-07 2016-03-15 Therapeutic Proteins International, LLC Preparative chromatography column and methods
US9783750B2 (en) 2012-02-16 2017-10-10 Smartflow Technologies, Inc. Biodiesel fuel production, separation methods and systems
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FR2993572B1 (fr) 2012-07-23 2016-04-15 Emd Millipore Corp Circuit pour liquide biologique comportant une vanne a pincement
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EP3016729B1 (de) 2013-07-05 2020-03-25 Laboratoire Francais du Fractionnement et des Biotechnologies Societe Anonyme Affinitätschromatografiematrix
US10324070B2 (en) 2014-04-23 2019-06-18 Chromatan Inc. High efficiency continuous countercurrent tangential chromatography
US10207225B2 (en) 2014-06-16 2019-02-19 Emd Millipore Corporation Single-pass filtration systems and processes
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CA3023486C (en) 2016-06-09 2022-03-29 Emd Millipore Corporation Radial-path filter elements, systems and methods of using same
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US11028124B2 (en) * 2018-05-07 2021-06-08 Repligen Corporation Methods, devices and systems for 3-stage filtration
AU2019332100A1 (en) 2018-08-29 2021-03-18 Merck Biodevelopment S.A.S. New purification method
JP2022500242A (ja) 2018-09-21 2022-01-04 サイティバ・スウェーデン・アクチボラグ 灌流バイオプロセシングシステムおよびそれを動作させる方法
EP4061826A1 (de) 2019-11-20 2022-09-28 CSL Behring AG Verfahren zum extrahieren eines proteins aus einer ausfällung und verfahren zum ausfällen von verunreinigungen
US20230242580A1 (en) * 2020-07-15 2023-08-03 Nutrition & Biosciences Usa 1, Llc Bioprocess with reduced fouling on surfaces
US20250027032A1 (en) * 2023-07-18 2025-01-23 Repligen Corporation System and methods for combined harvest and capture of a biologic
WO2026085439A1 (en) * 2024-10-18 2026-04-23 Repligen Corporation Harvest capture with settled resin

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Also Published As

Publication number Publication date
CA2361545C (en) 2009-01-27
IL144421A0 (en) 2002-05-23
EP1154827A4 (de) 2002-08-28
DE60031244D1 (de) 2006-11-23
NZ513242A (en) 2003-10-31
EP1154827A1 (de) 2001-11-21
WO2000048703B1 (en) 2000-12-07
CA2361545A1 (en) 2000-08-24
US6383380B1 (en) 2002-05-07
IL144421A (en) 2004-12-15
EP1154827B1 (de) 2006-10-11
WO2000048703A1 (en) 2000-08-24
DE60031244T2 (de) 2007-05-24
AU756832B2 (en) 2003-01-23
AU3008300A (en) 2000-09-04
DK1154827T3 (da) 2007-02-19
WO2000048703A9 (en) 2002-08-08

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