ATE342112T1 - Reinigung von biologischen substanzen - Google Patents

Reinigung von biologischen substanzen

Info

Publication number
ATE342112T1
ATE342112T1 AT00908806T AT00908806T ATE342112T1 AT E342112 T1 ATE342112 T1 AT E342112T1 AT 00908806 T AT00908806 T AT 00908806T AT 00908806 T AT00908806 T AT 00908806T AT E342112 T1 ATE342112 T1 AT E342112T1
Authority
AT
Austria
Prior art keywords
purification
biological substances
purifying
employing
types
Prior art date
Application number
AT00908806T
Other languages
English (en)
Inventor
Henry Kopf
Original Assignee
Ncsrt Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/255,186 external-priority patent/US6214221B1/en
Application filed by Ncsrt Inc filed Critical Ncsrt Inc
Application granted granted Critical
Publication of ATE342112T1 publication Critical patent/ATE342112T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B01D15/361—Ion-exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804—Affinity chromatography
    • B01D15/3809—Affinity chromatography of the antigen-antibody type, e.g. protein A, G or L chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Water Supply & Treatment (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Peptides Or Proteins (AREA)
  • Jellies, Jams, And Syrups (AREA)
AT00908806T 1999-02-22 2000-02-22 Reinigung von biologischen substanzen ATE342112T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/255,186 US6214221B1 (en) 1999-02-22 1999-02-22 Method and apparatus for purification of biological substances
US09/300,891 US6139746A (en) 1999-02-22 1999-04-28 Method and apparatus for purification of biological substances

Publications (1)

Publication Number Publication Date
ATE342112T1 true ATE342112T1 (de) 2006-11-15

Family

ID=26944506

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00908806T ATE342112T1 (de) 1999-02-22 2000-02-22 Reinigung von biologischen substanzen

Country Status (10)

Country Link
US (1) US6383380B1 (de)
EP (1) EP1154827B1 (de)
AT (1) ATE342112T1 (de)
AU (1) AU756832B2 (de)
CA (1) CA2361545C (de)
DE (1) DE60031244T2 (de)
DK (1) DK1154827T3 (de)
IL (1) IL144421A (de)
NZ (1) NZ513242A (de)
WO (1) WO2000048703A1 (de)

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US6214221B1 (en) * 1999-02-22 2001-04-10 Henry B. Kopf Method and apparatus for purification of biological substances
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KR100473703B1 (ko) * 2002-08-23 2005-03-10 한미약품 주식회사 형질전환 동물의 젖으로부터 재조합 펩타이드 또는단백질의 정제 방법
WO2004076695A1 (en) * 2003-02-24 2004-09-10 Gtc Biotherapeutics, Inc. Methods of tangential flow filtration and an apparatus therefore
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US7531632B2 (en) 2006-02-16 2009-05-12 Gtc Biotherapeutics, Inc. Clarification of transgenic milk using depth filtration
US10632237B2 (en) 2006-10-09 2020-04-28 Minnetronix, Inc. Tangential flow filter system for the filtration of materials from biologic fluids
US10850235B2 (en) 2006-10-09 2020-12-01 Minnetronix, Inc. Method for filtering cerebrospinal fluid (CSF) including monitoring CSF flow
ES2845146T3 (es) 2006-10-09 2021-07-26 Neurofluidics Inc Sistema de purificación de líquido cefalorraquídeo
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KR20100111097A (ko) * 2009-04-06 2010-10-14 삼성전자주식회사 표적물질 분리를 위한 미세유동장치 및 그 정제방법
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FR2961711B1 (fr) 2010-06-23 2012-08-17 Millipore Corp Poche pour circuit d'une installation de traitement de liquide biologique
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DE112012001444T5 (de) * 2011-03-25 2014-04-10 Receptors Llc Faser mit Mikrobenentfernungs- oder Mikrobizidwirkungsvermögen oder Vermögen zur Bewirkung von statischem Wachstum
FR2973396B1 (fr) 2011-03-28 2013-05-10 Millipore Corp Installation de traitement de liquide biologique
US9284346B2 (en) * 2011-09-07 2016-03-15 Therapeutic Proteins International, LLC Preparative chromatography column and methods
US9783750B2 (en) 2012-02-16 2017-10-10 Smartflow Technologies, Inc. Biodiesel fuel production, separation methods and systems
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FR2993572B1 (fr) 2012-07-23 2016-04-15 Emd Millipore Corp Circuit pour liquide biologique comportant une vanne a pincement
US10786784B2 (en) 2012-09-06 2020-09-29 Smartflow Technologies, Inc. Permeate channel alterations for counter current filtration for use in cross-flow filtration modules useful in osmotic systems
KR20160029840A (ko) 2013-07-05 2016-03-15 라보라토이레 프란카이즈 듀 프락티온네먼트 에트 데스 바이오테크놀로지스 친화성 크로마토그래피 매트릭스
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WO2015200691A1 (en) 2014-06-25 2015-12-30 Emd Millipore Corporation Compact spiral-wound filter elements, modules and systems
KR102079585B1 (ko) 2014-08-29 2020-02-21 이엠디 밀리포어 코포레이션 잔류물의 재순환을 이용한 싱글 패스 접선 유동 여과 시스템 및 접선 유동 여과 시스템
KR102095477B1 (ko) 2014-08-29 2020-04-01 이엠디 밀리포어 코포레이션 잔류물의 재순환에 의한 싱글 패스 접선 유동 여과 시스템 및 접선 유동 여과 시스템을 사용하여 액체를 여과하는 공정
US11147540B2 (en) 2015-07-01 2021-10-19 Minnetronix, Inc. Introducer sheath and puncture tool for the introduction and placement of a catheter in tissue
WO2017023419A1 (en) 2015-08-05 2017-02-09 Minnetronix, Inc. Tangential flow filter system for the filtration of materials from biologic fluids
CA3006975C (en) 2015-12-04 2022-02-22 Minnetronix, Inc. Systems and methods for the conditioning of cerebrospinal fluid
EP3468698B1 (de) 2016-06-09 2022-06-29 EMD Millipore Corporation Radialpfadfilterelemente, systeme und verfahren zum gebrauch davon
CN121314243A (zh) 2016-08-26 2026-01-13 思拓凡生物工艺研发有限公司 层析系统
CA3251145A1 (en) 2018-04-17 2025-07-08 Smartflow Technologies, Inc. Filter cassette article, and filter comprising same
US11028124B2 (en) 2018-05-07 2021-06-08 Repligen Corporation Methods, devices and systems for 3-stage filtration
EP3844170A1 (de) 2018-08-29 2021-07-07 Merck Biodevelopment S.A.S. Neues reinigungsverfahren
JP2022500242A (ja) 2018-09-21 2022-01-04 サイティバ・スウェーデン・アクチボラグ 灌流バイオプロセシングシステムおよびそれを動作させる方法
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JP2023535561A (ja) * 2020-07-15 2023-08-18 ニュートリション・アンド・バイオサイエンシーズ・ユーエスエー・ワン，エルエルシー 表面の付着物が低減されたバイオプロセス
WO2025019564A2 (en) * 2023-07-18 2025-01-23 Repligen Corporation System and methods for combined harvest and capture of a biologic

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Also Published As

Publication number Publication date
US6383380B1 (en) 2002-05-07
CA2361545A1 (en) 2000-08-24
AU756832B2 (en) 2003-01-23
EP1154827A4 (de) 2002-08-28
CA2361545C (en) 2009-01-27
EP1154827A1 (de) 2001-11-21
AU3008300A (en) 2000-09-04
EP1154827B1 (de) 2006-10-11
IL144421A0 (en) 2002-05-23
WO2000048703A1 (en) 2000-08-24
WO2000048703A9 (en) 2002-08-08
NZ513242A (en) 2003-10-31
DK1154827T3 (da) 2007-02-19
WO2000048703B1 (en) 2000-12-07
IL144421A (en) 2004-12-15
DE60031244T2 (de) 2007-05-24
DE60031244D1 (de) 2006-11-23

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