ATE345134T1 - Verwendung von indazol-derivaten zur behandlung von neuropathischen schmerzen - Google Patents

Verwendung von indazol-derivaten zur behandlung von neuropathischen schmerzen

Info

Publication number
ATE345134T1
ATE345134T1 AT04763164T AT04763164T ATE345134T1 AT E345134 T1 ATE345134 T1 AT E345134T1 AT 04763164 T AT04763164 T AT 04763164T AT 04763164 T AT04763164 T AT 04763164T AT E345134 T1 ATE345134 T1 AT E345134T1
Authority
AT
Austria
Prior art keywords
neuropathic pain
indazole derivatives
treat neuropathic
treat
indazole
Prior art date
Application number
AT04763164T
Other languages
English (en)
Inventor
Angelo Guglielmotti
Lorenzo Polenzani
Alessandra Alisi
Nicola Cazzolla
Original Assignee
Acraf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acraf filed Critical Acraf
Application granted granted Critical
Publication of ATE345134T1 publication Critical patent/ATE345134T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
AT04763164T 2003-07-18 2004-07-08 Verwendung von indazol-derivaten zur behandlung von neuropathischen schmerzen ATE345134T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT001468A ITMI20031468A1 (it) 2003-07-18 2003-07-18 Farmaco ativo nel dolore neuropatico

Publications (1)

Publication Number Publication Date
ATE345134T1 true ATE345134T1 (de) 2006-12-15

Family

ID=34131194

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04763164T ATE345134T1 (de) 2003-07-18 2004-07-08 Verwendung von indazol-derivaten zur behandlung von neuropathischen schmerzen

Country Status (21)

Country Link
US (1) US7638534B2 (de)
EP (1) EP1646387B1 (de)
JP (1) JP4881729B2 (de)
KR (1) KR101073993B1 (de)
CN (1) CN100427089C (de)
AR (1) AR045994A1 (de)
AT (1) ATE345134T1 (de)
AU (1) AU2004262878B2 (de)
CA (1) CA2526052C (de)
DE (1) DE602004003251T2 (de)
DK (1) DK1646387T3 (de)
EA (1) EA008144B1 (de)
ES (1) ES2275232T3 (de)
GE (1) GEP20084343B (de)
IL (1) IL172101A (de)
IT (1) ITMI20031468A1 (de)
MX (1) MXPA06000651A (de)
PL (1) PL1646387T3 (de)
PT (1) PT1646387E (de)
UA (1) UA81051C2 (de)
WO (1) WO2005013989A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20062230A1 (it) * 2006-11-22 2008-05-23 Acraf Composto 2-alchil-indazolico procedimento per preparalo e composizione farmaceutica che lo comprende
UA99927C2 (uk) * 2007-11-12 2012-10-25 Ацьенде Кимике Риуните Анджелини Франческо А.Чи.Р.А.Ф. С.П.А. Медикамент, який є активним при невропатичному болі
US8686147B2 (en) 2008-07-29 2014-04-01 Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. Compound with serotoninergic activity, process for preparing it and pharmaceutical composition comprising it

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ243993A (en) * 1991-08-20 1994-10-26 Smithkline Beecham Plc Pharmaceutical compositions having 5-ht4 receptor antagonist activity and selected compounds having such activity
US5580885A (en) * 1991-09-12 1996-12-03 Smithkline Beecham P.L.C. 5-HT4 receptor antagonists
MA22647A1 (fr) * 1991-09-14 1993-04-01 Smithkline Beecham Plc Procede de preparation d'un ester ou d'un amide d'un nouveau produit .
GB9120628D0 (en) 1991-09-27 1991-11-06 Fujisawa Pharmaceutical Co Pyrrolobenzoxazine derivatives and process for preparation thereof
ATE266033T1 (de) 1992-03-12 2004-05-15 Smithkline Beecham Plc N- (1-nbutyl-4-piperidyl)methyl -3,4-dihydro-2h- 1,3 oxazino 3,2-a indol-10-carboxamid oder ein pharmazeutisch annehmbares salz davon
US5864039A (en) * 1994-03-30 1999-01-26 Yoshitomi Pharmaceutical Industries, Ltd. Benzoic acid compounds and use thereof as medicaments
IL117438A (en) * 1995-03-16 2001-12-23 Lilly Co Eli Indazolecarboxamides, their preparation and pharmaceutical compositions containing them
IT1291569B1 (it) * 1997-04-15 1999-01-11 Angelini Ricerche Spa Indazolammidi come agenti serotoninergici
US6069152A (en) * 1997-10-07 2000-05-30 Eli Lilly And Company 5-HT4 agonists and antagonists
DE10132746A1 (de) * 2001-07-05 2003-02-06 Gruenenthal Gmbh Substituierte 1-Phenethylpiperidinverbindungen
US6624162B2 (en) * 2001-10-22 2003-09-23 Pfizer Inc. Imidazopyridine compounds as 5-HT4 receptor modulators
AU2003255767A1 (en) * 2002-08-10 2004-02-25 Astex Technology Limited 3-(carbonyl) 1h-indazole compounds as cyclin dependent kinases (cdk) inhibitors
ITMI20030287A1 (it) 2003-02-18 2004-08-19 Acraf Indazolammidi dotate di attivita' analgesica metodo, per
ITMI20030972A1 (it) * 2003-05-15 2004-11-16 Acraf Indazolo dotato di attivita' analgesica, metodo per prepararlo e composizione farmaceutica che lo comprende.

Also Published As

Publication number Publication date
DE602004003251T2 (de) 2007-05-10
MXPA06000651A (es) 2006-03-30
ITMI20031468A1 (it) 2005-01-19
AU2004262878A1 (en) 2005-02-17
WO2005013989A1 (en) 2005-02-17
AU2004262878B2 (en) 2009-12-17
KR101073993B1 (ko) 2011-10-17
JP4881729B2 (ja) 2012-02-22
IL172101A0 (en) 2009-02-11
CN100427089C (zh) 2008-10-22
HK1087026A1 (en) 2006-10-06
AR045994A1 (es) 2005-11-23
US20060183775A1 (en) 2006-08-17
GEP20084343B (en) 2008-03-25
KR20060033006A (ko) 2006-04-18
PT1646387E (pt) 2007-01-31
PL1646387T3 (pl) 2007-03-30
EP1646387B1 (de) 2006-11-15
DE602004003251D1 (de) 2006-12-28
IL172101A (en) 2011-08-31
US7638534B2 (en) 2009-12-29
EA008144B1 (ru) 2007-04-27
EA200600271A1 (ru) 2006-06-30
DK1646387T3 (da) 2007-03-19
CA2526052A1 (en) 2005-02-17
CA2526052C (en) 2011-08-30
CN1809356A (zh) 2006-07-26
UA81051C2 (en) 2007-11-26
EP1646387A1 (de) 2006-04-19
ES2275232T3 (es) 2007-06-01
JP2009513544A (ja) 2009-04-02

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