ATE345143T1 - Impfstoff umfassend aussenmembranvesikel gegen krankheiten verursacht durch i neisseria meningitidis/i serogruppe a und verfahren zur herstellung desselben - Google Patents

Impfstoff umfassend aussenmembranvesikel gegen krankheiten verursacht durch i neisseria meningitidis/i serogruppe a und verfahren zur herstellung desselben

Info

Publication number
ATE345143T1
ATE345143T1 AT01938851T AT01938851T ATE345143T1 AT E345143 T1 ATE345143 T1 AT E345143T1 AT 01938851 T AT01938851 T AT 01938851T AT 01938851 T AT01938851 T AT 01938851T AT E345143 T1 ATE345143 T1 AT E345143T1
Authority
AT
Austria
Prior art keywords
serogroup
vaccine
producing
same
outer membrane
Prior art date
Application number
AT01938851T
Other languages
English (en)
Inventor
Einar Rosenqvist
Kari N Harbak
Karin Nord
Lisbeth Meyer Noss
Audun Aase
Nydalen
Original Assignee
Statens Inst For Folkehelse
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=19911219&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE345143(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Statens Inst For Folkehelse filed Critical Statens Inst For Folkehelse
Application granted granted Critical
Publication of ATE345143T1 publication Critical patent/ATE345143T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
AT01938851T 2000-06-02 2001-06-05 Impfstoff umfassend aussenmembranvesikel gegen krankheiten verursacht durch i neisseria meningitidis/i serogruppe a und verfahren zur herstellung desselben ATE345143T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NO20002828A NO20002828D0 (no) 2000-06-02 2000-06-02 Proteinholdig vaksine mot Neisseria meningtidis serogruppe samt fremgangsmÕte ved fremstilling derav

Publications (1)

Publication Number Publication Date
ATE345143T1 true ATE345143T1 (de) 2006-12-15

Family

ID=19911219

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01938851T ATE345143T1 (de) 2000-06-02 2001-06-05 Impfstoff umfassend aussenmembranvesikel gegen krankheiten verursacht durch i neisseria meningitidis/i serogruppe a und verfahren zur herstellung desselben

Country Status (10)

Country Link
US (1) US20040131642A1 (de)
EP (1) EP1286696B1 (de)
AP (1) AP1690A (de)
AT (1) ATE345143T1 (de)
AU (1) AU2001264427A1 (de)
CA (1) CA2410652A1 (de)
DE (1) DE60124538D1 (de)
NO (1) NO20002828D0 (de)
OA (1) OA12278A (de)
WO (1) WO2001091788A1 (de)

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GB9928196D0 (en) 1999-11-29 2000-01-26 Chiron Spa Combinations of B, C and other antigens
WO2002009643A2 (en) 2000-07-27 2002-02-07 Children's Hospital & Research Center At Oakland Vaccines for broad spectrum protection against diseases caused by neisseria meningitidis
GB0130123D0 (en) 2001-12-17 2002-02-06 Microbiological Res Agency Outer membrane vesicle vaccine and its preparation
GB0220194D0 (en) 2002-08-30 2002-10-09 Chiron Spa Improved vesicles
WO2004046177A2 (en) 2002-11-15 2004-06-03 Chiron Srl Unexpected surface proteins in neisseria meningitidis
CU23313A1 (es) * 2002-11-27 2008-09-25 Inst Finlay Ct De Investigacia Mã0/00todo de obtenciã"n de estructuras cocleares. composiciones vacunales y adyuvantes basados en estructuras cocleares y sus intermediarios
AU2003288558A1 (en) * 2002-12-16 2004-07-09 Nasjonalt Folkehelseinstitutt Meningococcal vaccine based on outer membrane proteins porb2 and pora
GB0316560D0 (en) 2003-07-15 2003-08-20 Chiron Srl Vesicle filtration
CU23377A1 (es) * 2003-11-04 2009-05-28 Ct De Ingenieria Genetica Y Biotecnologia Metodo para la incorporacion de antigenos en vesiculas de membrana externa de bacterias y formulaciones resultantes
GB0416120D0 (en) 2004-07-19 2004-08-18 Health Prot Agency Stable compositions containing OMV's
GB0419627D0 (en) 2004-09-03 2004-10-06 Chiron Srl Immunogenic bacterial vesicles with outer membrane proteins
GB0424092D0 (en) 2004-10-29 2004-12-01 Chiron Srl Immunogenic bacterial vesicles with outer membrane proteins
ES2616294T3 (es) 2005-01-27 2017-06-12 Children's Hospital & Research Center At Oakland Vacunas de vesículas basadas en GNA1870 para protección de amplio espectro contra enfermedades provocadas por Neisseria meningitidis
WO2007139746A1 (en) 2006-05-22 2007-12-06 Biovest International Inc. Rotary actuator valve for a cell culture system
MX340096B (es) 2007-10-19 2016-06-27 Glaxosmithkline Biologicals Sa Formulaciones de vacuna meningococica.
BRPI0907843A2 (pt) 2008-02-21 2015-08-04 Novartis Ag Polipeptídeos de fhbp menigocócicos
PT2268618E (pt) 2008-03-03 2015-10-12 Novartis Ag Compostos e composições moduladores da actividade tlr
WO2009158142A1 (en) 2008-05-30 2009-12-30 The U.S.A., As Represented By The Secretary Of The Army, On Behalf Of Walter Reed Army Meningococcal multivalent native outer membrane vesicle vaccine, methods of making and use thereof
GB0822634D0 (en) 2008-12-11 2009-01-21 Novartis Ag Meningitis vaccines
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WO2010144734A1 (en) 2009-06-10 2010-12-16 Novartis Ag Benzonaphthyridine-containing vaccines
JP2013503148A (ja) 2009-08-27 2013-01-31 ノバルティス アーゲー アルミニウム、オリゴヌクレオチドおよびポリカチオンを含むアジュバント
JP2013502918A (ja) 2009-08-27 2013-01-31 ノバルティス アーゲー 髄膜炎菌ｆＨＢＰ配列を含むハイブリッドポリペプチド
JO3257B1 (ar) 2009-09-02 2018-09-16 Novartis Ag مركبات وتركيبات كمعدلات لفاعلية tlr
JP5988492B2 (ja) 2009-09-02 2016-09-07 ノバルティス アーゲー Ｔｌｒ活性モジュレーターを含む免疫原性組成物
GB0917003D0 (en) 2009-09-28 2009-11-11 Novartis Vaccines Inst For Global Health Srl Purification of bacterial vesicles
WO2011039631A2 (en) 2009-09-30 2011-04-07 Novartis Ag Expression of meningococcal fhbp polypeptides
US20130022633A1 (en) 2009-10-27 2013-01-24 University Of Florence MENINGOCOCCAL fHBP POLYPEPTIDES
WO2011057148A1 (en) 2009-11-05 2011-05-12 Irm Llc Compounds and compositions as tlr-7 activity modulators
BR112012014624A8 (pt) 2009-12-15 2017-12-26 Novartis Ag suspensão homogênea de compostos de imunopotenciação e usos dos destes
MX2012010609A (es) 2010-03-18 2012-10-03 Novartis Ag Vacunas adyuvadas para meningococos serogrupo b.
EP2549990A1 (de) 2010-03-23 2013-01-30 Irm Llc Verbindungen (cysteinbasierte lipopeptide) und zusammensetzungen als tlr2-agonisten zur behandlung von infektionen, entzündungen, atemwegserkrankungen etc.
ES2759484T3 (es) 2010-09-10 2020-05-11 Glaxosmithkline Biologicals Sa Meningococo que sobreexpresa NadA y/o NHBA y vesículas de la membrana externa derivadas del mismo
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US10598666B2 (en) 2012-03-08 2020-03-24 Glaxosmithkline Biologicals Sa In vitro potency assay for protein-based meningococcal vaccines
EP2861247B1 (de) 2012-06-14 2020-12-09 GlaxoSmithKline Biologicals SA Impfstoffe gegen serogruppe-x-meningokokken
CA2920957A1 (en) 2012-08-28 2014-03-06 Biovest International, Inc. Biomanufacturing suite and methods for large-scale production of cells, viruses, and biomolecules
RU2015106930A (ru) 2012-09-06 2016-10-20 Новартис Аг Комбинированные вакцины с менингококком серогруппы в и к/д/с
MX363529B (es) 2012-09-18 2019-03-27 Novartis Ag Vesículas de membrana externa.
CA2900454A1 (en) 2013-02-07 2014-08-14 Glaxosmithkline Biologicals Sa Pharmaceutical compositions comprising vesicles
KR102779223B1 (ko) 2014-02-28 2025-03-07 글락소스미스클라인 바이오로지칼즈 에스.에이. 변형된 수막구균 fhbp 폴리펩티드
US11066453B2 (en) 2015-05-18 2021-07-20 Biomvis Srl Immunogenic compositions containing bacterial outer membrane vesicles and therapeutic uses thereof
US12109259B2 (en) 2016-09-02 2024-10-08 Glaxosmithkline Biologicals Sa Vaccines for Neisseria gonorrhoeae
EP3607967A1 (de) 2018-08-09 2020-02-12 GlaxoSmithKline Biologicals S.A. Modifizierte meningokokken fhbp polypeptide
AU2019376832B2 (en) 2018-11-06 2024-01-25 Glaxosmithkline Biologicals Sa Immunogenic compositions
CN112410239B (zh) * 2019-08-22 2023-03-24 四川大学 细菌膜囊泡及其制备方法与应用
WO2025175304A2 (en) 2024-02-16 2025-08-21 Sanofi Pasteur Inc. Process for the preparation of deoxycholic acid
WO2025183190A1 (ja) * 2024-02-28 2025-09-04 株式会社ヤクルト本社 グラム陽性菌の膜小胞の製造方法及びその膜小胞の利用

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JP2631035B2 (ja) * 1991-03-12 1997-07-16 アメリカ合衆国 多糖類−タンパク質複合体
US5324442A (en) * 1992-06-16 1994-06-28 Kansas State University Research Foundation Fermentation process for the production of calcium magnesium road deicer
GB9726398D0 (en) * 1997-12-12 1998-02-11 Isis Innovation Polypeptide and coding sequences
ATE446368T1 (de) * 1998-01-14 2009-11-15 Novartis Vaccines & Diagnostic Antigene aus neisseria meningitidis
GB9820003D0 (en) * 1998-09-14 1998-11-04 Smithkline Beecham Biolog Novel compounds
CA2359492A1 (en) * 1999-01-15 2000-07-20 Smithkline Beecham Biologicals S.A. Neisseria meningitidis antigen
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WO2002009643A2 (en) * 2000-07-27 2002-02-07 Children's Hospital & Research Center At Oakland Vaccines for broad spectrum protection against diseases caused by neisseria meningitidis
GB0103170D0 (en) * 2001-02-08 2001-03-28 Smithkline Beecham Biolog Vaccine composition
GB0024200D0 (en) * 2000-10-03 2000-11-15 Smithkline Beecham Sa Component vaccine

Also Published As

Publication number Publication date
WO2001091788A1 (en) 2001-12-06
NO20002828D0 (no) 2000-06-02
OA12278A (en) 2006-05-11
DE60124538D1 (de) 2006-12-28
AP2002002681A0 (en) 2002-12-31
AP1690A (en) 2006-12-11
EP1286696B1 (de) 2006-11-15
EP1286696A1 (de) 2003-03-05
US20040131642A1 (en) 2004-07-08
CA2410652A1 (en) 2001-12-06
AU2001264427A1 (en) 2001-12-11

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