ATE345343T1 - Triazolo(4,5-d)pyrimidinderivate als antithrombotische verbindungen - Google Patents

Triazolo(4,5-d)pyrimidinderivate als antithrombotische verbindungen

Info

Publication number
ATE345343T1
ATE345343T1 AT01983011T AT01983011T ATE345343T1 AT E345343 T1 ATE345343 T1 AT E345343T1 AT 01983011 T AT01983011 T AT 01983011T AT 01983011 T AT01983011 T AT 01983011T AT E345343 T1 ATE345343 T1 AT E345343T1
Authority
AT
Austria
Prior art keywords
triazolo
compounds
antithrbotic
pyrimidine derivatives
medicaments
Prior art date
Application number
AT01983011T
Other languages
English (en)
Inventor
Roger Brown
Simon Guile
Garry Pairaudeau
Brian Springthorpe
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE345343T1 publication Critical patent/ATE345343T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT01983011T 2000-11-09 2001-11-07 Triazolo(4,5-d)pyrimidinderivate als antithrombotische verbindungen ATE345343T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0004099A SE0004099D0 (sv) 2000-11-09 2000-11-09 Novel compounds

Publications (1)

Publication Number Publication Date
ATE345343T1 true ATE345343T1 (de) 2006-12-15

Family

ID=20281756

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01983011T ATE345343T1 (de) 2000-11-09 2001-11-07 Triazolo(4,5-d)pyrimidinderivate als antithrombotische verbindungen

Country Status (9)

Country Link
US (1) US7034032B2 (de)
EP (1) EP1335919B1 (de)
JP (1) JP4202752B2 (de)
AT (1) ATE345343T1 (de)
AU (1) AU2002214467A1 (de)
DE (1) DE60124581T2 (de)
ES (1) ES2274908T3 (de)
SE (1) SE0004099D0 (de)
WO (1) WO2002038570A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0219746D0 (en) * 2002-08-23 2002-10-02 Inst Of Ex Botany Ascr Azapurine derivatives
GB0512844D0 (en) * 2005-06-23 2005-08-03 Novartis Ag Organic compounds
US7752475B2 (en) * 2006-06-27 2010-07-06 International Business Machines Corporation Late data launch for a double data rate elastic interface
US7734944B2 (en) * 2006-06-27 2010-06-08 International Business Machines Corporation Mechanism for windaging of a double rate driver
JP2010508350A (ja) 2006-10-31 2010-03-18 ヤンセン ファーマシューティカ エヌ．ベー． Ａｄｐｐ２ｙ１２レセプターアンタゴニストとしてのトリアゾロピリミジン誘導体

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8826205D0 (en) * 1988-11-09 1988-12-14 Wellcome Found Heterocyclic compounds
AR017014A1 (es) * 1997-07-22 2001-08-22 Astrazeneca Ab Compuestos de triazolo [4,5-d]pirimidina, composiciones farmaceuticas, uso de los mismos para preparar medicamentos y procesos para la preparacionde dichos compuestos

Also Published As

Publication number Publication date
US20040023988A1 (en) 2004-02-05
EP1335919B1 (de) 2006-11-15
JP2004513172A (ja) 2004-04-30
HK1056362A1 (en) 2004-02-13
US7034032B2 (en) 2006-04-25
DE60124581T2 (de) 2007-06-28
ES2274908T3 (es) 2007-06-01
AU2002214467A1 (en) 2002-05-21
JP4202752B2 (ja) 2008-12-24
EP1335919A1 (de) 2003-08-20
WO2002038570A1 (en) 2002-05-16
DE60124581D1 (de) 2006-12-28
SE0004099D0 (sv) 2000-11-09

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Legal Events

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