ATE345803T1 - Neue methoden unter verwendung von cholinesteraseinhibitoren - Google Patents
Neue methoden unter verwendung von cholinesteraseinhibitorenInfo
- Publication number
- ATE345803T1 ATE345803T1 AT01922272T AT01922272T ATE345803T1 AT E345803 T1 ATE345803 T1 AT E345803T1 AT 01922272 T AT01922272 T AT 01922272T AT 01922272 T AT01922272 T AT 01922272T AT E345803 T1 ATE345803 T1 AT E345803T1
- Authority
- AT
- Austria
- Prior art keywords
- cholinesterase inhibitors
- new methods
- cholinesterase
- inhibitors
- donepezil
- Prior art date
Links
- 239000000544 cholinesterase inhibitor Substances 0.000 title abstract 2
- ADEBPBSSDYVVLD-UHFFFAOYSA-N donepezil Chemical compound O=C1C=2C=C(OC)C(OC)=CC=2CC1CC(CC1)CCN1CC1=CC=CC=C1 ADEBPBSSDYVVLD-UHFFFAOYSA-N 0.000 abstract 2
- 208000028698 Cognitive impairment Diseases 0.000 abstract 1
- 238000002512 chemotherapy Methods 0.000 abstract 1
- 208000010877 cognitive disease Diseases 0.000 abstract 1
- 229960003530 donepezil Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18674400P | 2000-03-03 | 2000-03-03 | |
| US19761000P | 2000-04-18 | 2000-04-18 | |
| US22078300P | 2000-07-25 | 2000-07-25 | |
| US25922601P | 2001-01-03 | 2001-01-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE345803T1 true ATE345803T1 (de) | 2006-12-15 |
Family
ID=27497683
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01922272T ATE345803T1 (de) | 2000-03-03 | 2001-03-05 | Neue methoden unter verwendung von cholinesteraseinhibitoren |
Country Status (11)
| Country | Link |
|---|---|
| US (7) | US20020035128A1 (de) |
| EP (5) | EP2133078A1 (de) |
| JP (1) | JP2003525903A (de) |
| AT (1) | ATE345803T1 (de) |
| AU (1) | AU2001249091A1 (de) |
| CY (1) | CY1107997T1 (de) |
| DE (1) | DE60124730T2 (de) |
| DK (1) | DK1311272T3 (de) |
| ES (1) | ES2275670T3 (de) |
| PT (1) | PT1311272E (de) |
| WO (1) | WO2001066114A1 (de) |
Families Citing this family (91)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030153598A1 (en) * | 2000-07-25 | 2003-08-14 | Raymond Pratt | Methods for treating Parkinson's disease with cholinesterase inhibitors |
| EP2133078A1 (de) * | 2000-03-03 | 2009-12-16 | Eisai R&D Management Co., Ltd. | Verwendung eines Cholinesterase-Hemmers für die Behandlung von kognitiven Beeinträchtigungen und/oder Demenz, die mit Gehirntumoren in Zusammenhang gebracht oder davon verursacht wird |
| US20060183776A9 (en) * | 2000-03-03 | 2006-08-17 | Eisai Co., Ltd. | Liquid dosage formulations of donepezil |
| EP1372620A2 (de) * | 2001-03-15 | 2004-01-02 | Saegis Pharmaceuticals | Verfahren zur wiederherstellung der kognitiven funktion nach systemischem stress |
| CA2459146A1 (en) * | 2001-08-30 | 2003-03-13 | Ortho-Mcneil Pharmaceutical, Inc. | Treatment of dementia and memory disorders with anticonvulsants and acetylcholinesterase inhibitors |
| WO2003032914A2 (en) * | 2001-10-17 | 2003-04-24 | Eisai Co., Ltd. | Methods for treating substance abuse with cholinesterase inhibitors |
| US20050107432A1 (en) * | 2002-01-22 | 2005-05-19 | Yoichi Iimura | Sigma receptor binder containing indanone derivative |
| US20030162770A1 (en) * | 2002-02-22 | 2003-08-28 | Davis Bonnie M. | Use of modulators of nicotinic receptors for treatment of cognitive dysfunction |
| WO2004034963A2 (en) * | 2002-05-17 | 2004-04-29 | Eisai Co., Ltd. | Methods and compositions using cholinesterase inhibitors |
| US20070053976A1 (en) * | 2002-05-17 | 2007-03-08 | Eisai R & D Management Co., Ltd. | Novel combination of drugs as antidepressant |
| US20060129385A1 (en) * | 2002-07-22 | 2006-06-15 | Heller James H | Cholinergic therapy for individuals with learning disabilities |
| AU2003287433A1 (en) * | 2002-11-01 | 2004-06-07 | Oregon Health And Science University | Treatment of hyperkinetic movement disorder with donepezil |
| AU2004216360B2 (en) * | 2003-02-27 | 2009-09-17 | Eisai R & D Management Co., Ltd. | Pharmaceutical composition for treatment of drug dependence |
| EP1622569B1 (de) | 2003-04-24 | 2015-12-02 | Incyte Corporation | Aza-spiro-alkan-derivate als hemmer von metallproteasen |
| IL155666A (en) * | 2003-04-29 | 2013-12-31 | Neurim Pharma 1991 | Insomnia treatment |
| US9119846B2 (en) * | 2003-04-29 | 2015-09-01 | Neurim Pharmaceuticals (1991) Ltd. | Method and composition for enhancing cognition in alzheimer's patients |
| MXPA05012614A (es) * | 2003-05-23 | 2006-08-23 | Sention Inc | Metodos para el tratamiento del deterioro cognitivo y mejorar la cognicion. |
| MXPA05013960A (es) | 2003-06-17 | 2006-02-24 | Pfizer | Nuevos compuestos. |
| EP1666066A4 (de) * | 2003-09-19 | 2007-03-28 | Eisai R&D Man Co Ltd | Mittel zur behandlung von down-syndrom |
| WO2005065645A2 (en) * | 2003-12-31 | 2005-07-21 | Actavis Group Hf | Donepezil formulations |
| US20050277129A1 (en) * | 2004-01-22 | 2005-12-15 | Genaissance Pharmaceuticals | APOE genetic markers associated with age of onset of Alzheimer's disease |
| JP2007519733A (ja) * | 2004-01-26 | 2007-07-19 | コーテックス ファーマシューティカルズ インコーポレーティッド | アンパカインにより誘導されるシナプス応答促通のコリンエステラーゼ阻害剤による増強方法 |
| WO2005074917A1 (en) * | 2004-01-30 | 2005-08-18 | Axonyx, Inc. | Methods for treatment of complications of diabetes |
| JP2007529555A (ja) * | 2004-03-18 | 2007-10-25 | ザ ブライハム アンド ウイメンズ ホスピタル, インコーポレイテッド | シヌクレイノパチーを治療する方法 |
| US20060106060A1 (en) * | 2004-03-18 | 2006-05-18 | The Brigham And Women's Hospital, Inc. | Methods for the treatment of synucleinopathies (Lansbury) |
| CA2559285A1 (en) * | 2004-03-18 | 2005-09-29 | Brigham And Women's Hospital, Inc. | Methods for the treatment of synucleinopathies |
| US20070293539A1 (en) * | 2004-03-18 | 2007-12-20 | Lansbury Peter T | Methods for the treatment of synucleinopathies |
| US20050272722A1 (en) * | 2004-03-18 | 2005-12-08 | The Brigham And Women's Hospital, Inc. | Methods for the treatment of synucleinopathies |
| TW200533371A (en) * | 2004-04-15 | 2005-10-16 | Dainippon Pharmaceutical Co | Medicament comprising a combination of an acetylcholinesterase inhibitor and a 5-substituted-3-oxadiazolyl-1,6-naphthyridin-2(1h)-one derivative |
| US20060135507A1 (en) * | 2004-08-13 | 2006-06-22 | Osamu Yokoyama | Therapeutic agent for overactive bladder involved in aging |
| WO2006037047A2 (en) * | 2004-09-27 | 2006-04-06 | Bridge Pharma, Inc. | The r-isomer of 2-{2-[n-(2-indanyl)-n-phenylamino]ethyl}piperidine and other dermal anesthetic agents |
| US7718674B2 (en) * | 2004-09-27 | 2010-05-18 | Bridge Pharma, Inc. | Methods of relieving neuropathic pain with the S-isomer of 2-{2[N-(2-indanyl)-N-phenylamino]ethyl}piperidine |
| AU2006232517A1 (en) * | 2005-04-04 | 2006-10-12 | Eisai R&D Management Co., Ltd. | Dihydropyridine compounds and compositions for headaches |
| GB0605544D0 (en) * | 2006-03-20 | 2006-04-26 | Univ Nottingham | Genetic Markers For Alzheimer Disease |
| US7858611B2 (en) * | 2006-05-09 | 2010-12-28 | Braincells Inc. | Neurogenesis by modulating angiotensin |
| US7910108B2 (en) * | 2006-06-05 | 2011-03-22 | Incyte Corporation | Sheddase inhibitors combined with CD30-binding immunotherapeutics for the treatment of CD30 positive diseases |
| CA2655809C (en) * | 2006-07-21 | 2013-10-01 | Bridge Pharma, Inc. | Dermal anesthetic compounds |
| US8012994B1 (en) | 2006-09-22 | 2011-09-06 | Sevastyanov Victor V | Method for the treatment of sensorineural hearing loss with donepezil hydrochloride (ARICEPT®) |
| RU2452474C2 (ru) * | 2006-12-01 | 2012-06-10 | Нитто Денко Корпорейшн | Стабилизированная адгезивная композиция, содержащая донепезил |
| US20100062045A1 (en) * | 2006-12-01 | 2010-03-11 | Nitto Denko Corporation | Method for suppressing coloring of adhesive prepartion containing donepezil and method for reducing amounts of donepezil-related substances formed |
| WO2008111590A2 (en) * | 2007-03-05 | 2008-09-18 | Eisai R & D Management Co., Ltd. | Ampa and nmda receptor antagonists for neurodegenerative diseases |
| WO2008139984A1 (en) * | 2007-04-26 | 2008-11-20 | Eisai R & D Management Co., Ltd. | Cinnamide compounds for dementia |
| JP2010526825A (ja) * | 2007-05-10 | 2010-08-05 | エーエムアール テクノロジー インコーポレイテッド | アリール置換およびヘテロアリール置換テトラヒドロベンゾ−1,4−ジアゼピンならびにノルエピネフリン、ドーパミンおよびセロトニンの再取り込みを遮断するためのその使用 |
| JP2011502966A (ja) * | 2007-10-31 | 2011-01-27 | アルセレス ファーマシューティカルズ, インコーポレイテッド | ドーパミントランスポーターレベルを評価することによるレビー小体型認知症の診断およびレビー小体型認知症の処置のモニタリングのための方法 |
| US20090156561A1 (en) * | 2007-12-13 | 2009-06-18 | Seed John C | Use of Cholinesterase Inhibitors In Smoking Cessation |
| WO2009151683A2 (en) * | 2008-03-12 | 2009-12-17 | Link Medicine Corporation | Quinolinone farnesyl transferase inhibitors for the treatment of synucleinopathies and other indications |
| EP2291181B9 (de) | 2008-04-18 | 2013-09-11 | University College Dublin National University Of Ireland, Dublin | Captodiamine zur Behandlung von depressionartigen Symptomen |
| EP2288345B1 (de) | 2008-04-18 | 2015-06-10 | University College Dublin National University Of Ireland, Dublin | Psychopharmazeutika |
| US20090291127A1 (en) * | 2008-05-21 | 2009-11-26 | Jianye Wen | Transdermal anti-dementia active agent formulations and methods for using the same |
| RU2481826C2 (ru) * | 2008-05-30 | 2013-05-20 | Нитто Денко Корпорейшн | Содержащий донепезил адгезивный препарат и упаковка для него |
| CN102046171B (zh) * | 2008-05-30 | 2013-06-19 | 日东电工株式会社 | 经皮吸收制剂 |
| JP2012504163A (ja) * | 2008-09-30 | 2012-02-16 | テイコク ファーマ ユーエスエー インコーポレーテッド | 経皮持続送達ドネペジル組成物および該組成物を使用する方法 |
| NZ593090A (en) * | 2008-11-13 | 2013-06-28 | Link Medicine Corp | Azaquinolinone derivatives and uses thereof |
| US20100331363A1 (en) * | 2008-11-13 | 2010-12-30 | Link Medicine Corporation | Treatment of mitochondrial disorders using a farnesyl transferase inhibitor |
| US20110060005A1 (en) * | 2008-11-13 | 2011-03-10 | Link Medicine Corporation | Treatment of mitochondrial disorders using a farnesyl transferase inhibitor |
| CA2758321A1 (en) * | 2009-04-13 | 2010-10-21 | Theravance, Inc. | 5-ht4 receptor agonist compounds for treatment of cognitive disorders |
| US20100178307A1 (en) * | 2010-01-13 | 2010-07-15 | Jianye Wen | Transdermal anti-dementia active agent formulations and methods for using the same |
| AU2011215870B2 (en) | 2010-02-09 | 2016-01-28 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
| EP2366378A1 (de) | 2010-03-01 | 2011-09-21 | Dexcel Pharma Technologies Ltd. | Donepezilformulierungen mit verzögerter Freisetzung |
| US20110251239A1 (en) | 2010-04-07 | 2011-10-13 | Eisai Inc. | Combination therapy for the treatment of dementia |
| GR1007368B (el) | 2010-05-27 | 2011-08-02 | Alapis Α.Β.Ε.Ε., | Ποσιμα φαρμακευτικα διαλυματα για τη θεραπεια των συμπτωματων της ανοιας |
| WO2011151359A1 (en) | 2010-06-02 | 2011-12-08 | Noscira, S.A. | Combined treatment with a cholinesterase inhibitor and a thiadiazolidinedione derivative |
| JP5951625B2 (ja) | 2010-11-24 | 2016-07-13 | ザ・トラスティーズ・オブ・コランビア・ユニバーシティー・イン・ザ・シティー・オブ・ニューヨークThe Trustees Of Columbia University In The City Of New York | 加齢性黄斑変性症およびシュタルガルト病の処置のための非レチノイドrbp4アンタゴニスト |
| US20120225922A1 (en) | 2011-03-04 | 2012-09-06 | Qr Pharma | Effective Amounts of (3aR)-1,3a,8-Trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo [2,3-b]indol-5-yl Phenylcarbamate and Methods of Treating or Preventing Neurodegeneration |
| WO2013109543A1 (en) * | 2012-01-20 | 2013-07-25 | The Board Of Trustees Of The Leland Stanford Junior University | Small molecule cmklr1 antagonists in demyelinating disease |
| US9333202B2 (en) | 2012-05-01 | 2016-05-10 | The Trustees Of Columbia University In The City Of New York | Non-retinoid antagonists for treatment of age-related macular degeneration and stargardt disease |
| US20140206667A1 (en) * | 2012-11-14 | 2014-07-24 | Michela Gallagher | Methods and compositions for treating schizophrenia |
| US9265458B2 (en) | 2012-12-04 | 2016-02-23 | Sync-Think, Inc. | Application of smooth pursuit cognitive testing paradigms to clinical drug development |
| US9380976B2 (en) | 2013-03-11 | 2016-07-05 | Sync-Think, Inc. | Optical neuroinformatics |
| WO2014152018A1 (en) | 2013-03-14 | 2014-09-25 | The Trustees Of Columbia University In The City Of New York | Octahydrocyclopentapyrroles, their preparation and use |
| US9944644B2 (en) | 2013-03-14 | 2018-04-17 | The Trustees Of Columbia University In The City Of New York | Octahydropyrrolopyrroles their preparation and use |
| EP3495357B1 (de) | 2013-03-14 | 2021-05-05 | The Trustees of Columbia University in the City of New York | 4-phenylpiperidine, deren herstellung und verwendung |
| US9938291B2 (en) | 2013-03-14 | 2018-04-10 | The Trustess Of Columbia University In The City Of New York | N-alkyl-2-phenoxyethanamines, their preparation and use |
| WO2014144663A1 (en) | 2013-03-15 | 2014-09-18 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
| JP6433482B2 (ja) | 2013-03-15 | 2018-12-05 | エージンバイオ, インコーポレイテッド | 認知機能を改善するための方法および組成物 |
| US9359315B2 (en) * | 2013-09-10 | 2016-06-07 | Arrien Pharmaceuticals Llc | Substituted 2,3-dihydro-1H-inden-1-one retinoic acid-related orphan nuclear receptor antagonists for treating multiple sclerosis |
| SG11201608943VA (en) | 2014-04-30 | 2016-11-29 | Univ Columbia | Substituted 4-phenylpiperidines, their preparaiton and use |
| MA41291A (fr) | 2014-12-30 | 2017-11-07 | Forma Therapeutics Inc | Dérivés de la pyrrolotriazinone et de l'imidazotriazinone en tant qu'inhibiteurs de la protéase spécifique de l'ubiquitine n° 7 (usp7) pour le traitement d'un cancer |
| AR103297A1 (es) | 2014-12-30 | 2017-05-03 | Forma Therapeutics Inc | Pirrolo y pirazolopirimidinas como inhibidores de la proteasa 7 específica de ubiquitina |
| US9840491B2 (en) | 2015-02-05 | 2017-12-12 | Forma Therapeutics, Inc. | Quinazolinones and azaquinazolinones as ubiquitin-specific protease 7 inhibitors |
| US9938300B2 (en) | 2015-02-05 | 2018-04-10 | Forma Therapeutics, Inc. | Isothiazolopyrimidinones, pyrazolopyrimidinones, and pyrrolopyrimidinones as ubiquitin-specific protease 7 inhibitors |
| EP3253765A1 (de) | 2015-02-05 | 2017-12-13 | Forma Therapeutics, Inc. | Thienopyrimidinone als ubiquitin-spezifische protease 7-inhibitoren |
| WO2016191288A1 (en) | 2015-05-22 | 2016-12-01 | Agenebio, Inc. | Extended release pharmaceutical compositions of levetiracetam |
| WO2017030968A1 (en) * | 2015-08-14 | 2017-02-23 | Qr Pharma | Methods of treatment or prevention of acute brain or nerve injuries |
| WO2018217892A1 (en) | 2017-05-24 | 2018-11-29 | Qr Pharma, Inc. | Prevention or treatment of disease states due to metal dis-homeostasis via administration of posiphen to healthy or sick humans |
| JP2021501210A (ja) | 2017-10-30 | 2021-01-14 | モントリオール ハート インスティテュート | 血漿コレステロールの上昇を処置する方法 |
| WO2019243453A1 (en) * | 2018-06-19 | 2019-12-26 | Universidad Pablo De Olavide | Compositions for treating and/or preventing protein-aggregation diseases |
| TWI834795B (zh) | 2019-01-08 | 2024-03-11 | 日商杏林製藥股份有限公司 | 15-pgdh抑制劑 |
| EP3917911A1 (de) | 2019-01-31 | 2021-12-08 | Kyorin Pharmaceutical Co., Ltd. | 15-pgdh-inhibitoren |
| AU2020315331A1 (en) * | 2019-07-16 | 2022-02-03 | Rush University Medical Center | Use of a benzoate containing composition to treat neurodegenerative disorders |
| US12582632B2 (en) | 2021-05-18 | 2026-03-24 | Annovis Bio, Inc. | Inhibition of neurological injuries due to infections via administration of Butanetap and analogs thereof |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL74497A (en) * | 1985-03-05 | 1990-02-09 | Proterra Ag | Pharmaceutical compositions containing phenyl carbamate derivatives and certain phenyl carbamate derivatives |
| US4826843A (en) * | 1985-07-08 | 1989-05-02 | Bristol-Myers | Cerebral function enhancing diazinylpiperidine derivatives |
| FI95572C (fi) * | 1987-06-22 | 1996-02-26 | Eisai Co Ltd | Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi |
| JP2777159B2 (ja) * | 1988-12-22 | 1998-07-16 | エーザイ株式会社 | 環状アミン誘導体を含有する医薬 |
| JP3075566B2 (ja) | 1990-05-15 | 2000-08-14 | エーザイ株式会社 | 光学活性インダノン誘導体 |
| JP2965675B2 (ja) | 1990-11-21 | 1999-10-18 | エーザイ株式会社 | (―)―1―ベンジル―4―〔(5,6―ジメトキシ―1―インダノン)―2―イル〕メチルピペリジンの製造方法 |
| US5668117A (en) * | 1991-02-22 | 1997-09-16 | Shapiro; Howard K. | Methods of treating neurological diseases and etiologically related symptomology using carbonyl trapping agents in combination with previously known medicaments |
| WO1993003034A1 (en) * | 1991-07-29 | 1993-02-18 | Warner-Lambert Company | Quinazoline derivatives as acetylcholinesterase inhibitors |
| SE9103752D0 (sv) * | 1991-12-18 | 1991-12-18 | Astra Ab | New compounds |
| WO1997046526A1 (en) | 1996-06-07 | 1997-12-11 | Eisai Co., Ltd. | Stable polymorphs of donepezil (1-benzyl-4-[(5,6-dimethoxy-1-indanon)-2-yl]methylpiperidine) hydrochloride and process for production |
| SK285312B6 (sk) | 1996-06-07 | 2006-10-05 | Eisai Co., Ltd. | Polymorf (III) donepezil hydrochloridu, spôsob jeho výroby a terapeutický prostriedok s jeho obsahom |
| TW513409B (en) | 1996-06-07 | 2002-12-11 | Eisai Co Ltd | Polymorphs of donepezil hydrochloride |
| US5965571A (en) * | 1996-08-22 | 1999-10-12 | New York University | Cholinesterase inhibitors for treatment of Parkinson's disease |
| ES2200313T3 (es) | 1997-03-03 | 2004-03-01 | Eisai Co., Ltd. | Uso de inhibidores de la colinesterasa para tratar trastornos de la atencion. |
| US6274603B1 (en) * | 1997-09-24 | 2001-08-14 | Mcgill University | Methods for increasing ApoE levels for the treatment of neurodegenerative disease |
| ES2218869T3 (es) | 1997-12-05 | 2004-11-16 | Eisai Co., Ltd. | Cristales polimorficos de donepezil y un proceso para produccion de dichos cristales. |
| ATE292116T1 (de) | 1998-01-16 | 2005-04-15 | Eisai Co Ltd | Verfahren zur herstellung von donepezilderivaten |
| US6193993B1 (en) | 1998-03-03 | 2001-02-27 | Eisai Co., Ltd. | Suppository containing an antidementia medicament |
| EP1025858A4 (de) | 1998-08-28 | 2009-03-11 | Eisai R&D Man Co Ltd | Arzneimittel mit verminderter bitterkeit usw. |
| IT1304904B1 (it) | 1998-09-11 | 2001-04-05 | Eisai Co Ltd | Derivati anticolinesterasici per il trattamento delle sindromidolorose funzionali e/o organiche |
| ATE254928T1 (de) | 1999-03-31 | 2003-12-15 | Eisai Co Ltd | Stabilisierte zusammensetzung mit nootropen wirkstoffen |
| US20030153598A1 (en) * | 2000-07-25 | 2003-08-14 | Raymond Pratt | Methods for treating Parkinson's disease with cholinesterase inhibitors |
| US20060183776A9 (en) * | 2000-03-03 | 2006-08-17 | Eisai Co., Ltd. | Liquid dosage formulations of donepezil |
| EP2133078A1 (de) * | 2000-03-03 | 2009-12-16 | Eisai R&D Management Co., Ltd. | Verwendung eines Cholinesterase-Hemmers für die Behandlung von kognitiven Beeinträchtigungen und/oder Demenz, die mit Gehirntumoren in Zusammenhang gebracht oder davon verursacht wird |
| WO2001066096A2 (en) | 2000-03-06 | 2001-09-13 | Immune Network Ltd. | Compositions for prevention and treatment of dementia |
| US20010036949A1 (en) | 2000-05-09 | 2001-11-01 | Coe Jotham Wadsworth | Pharmaceutical composition and method of treatment of diseases of cognitive dysfunction in a mammal |
| WO2003024450A1 (en) | 2001-09-20 | 2003-03-27 | Eisai Co., Ltd. | Methods for treating prion diseases |
| WO2003024456A1 (en) | 2001-09-20 | 2003-03-27 | Eisai Co., Ltd. | Methods for treating and preventing migraines |
| WO2003032914A2 (en) | 2001-10-17 | 2003-04-24 | Eisai Co., Ltd. | Methods for treating substance abuse with cholinesterase inhibitors |
| AU2003228796A1 (en) | 2002-05-01 | 2003-11-17 | Eisai Co., Ltd. | Cholinesterase inhibitors to prevent injuries caused by chemicals |
| WO2004034963A2 (en) | 2002-05-17 | 2004-04-29 | Eisai Co., Ltd. | Methods and compositions using cholinesterase inhibitors |
| AU2003287433A1 (en) * | 2002-11-01 | 2004-06-07 | Oregon Health And Science University | Treatment of hyperkinetic movement disorder with donepezil |
-
2001
- 2001-03-05 EP EP09011084A patent/EP2133078A1/de not_active Withdrawn
- 2001-03-05 EP EP09011085A patent/EP2140868A1/de not_active Withdrawn
- 2001-03-05 DK DK01922272T patent/DK1311272T3/da active
- 2001-03-05 JP JP2001564766A patent/JP2003525903A/ja active Pending
- 2001-03-05 AT AT01922272T patent/ATE345803T1/de active
- 2001-03-05 EP EP09011050A patent/EP2130538A1/de not_active Withdrawn
- 2001-03-05 EP EP01922272A patent/EP1311272B1/de not_active Expired - Lifetime
- 2001-03-05 WO PCT/US2001/007027 patent/WO2001066114A1/en not_active Ceased
- 2001-03-05 AU AU2001249091A patent/AU2001249091A1/en not_active Abandoned
- 2001-03-05 ES ES01922272T patent/ES2275670T3/es not_active Expired - Lifetime
- 2001-03-05 EP EP09011051A patent/EP2138177A1/de not_active Withdrawn
- 2001-03-05 PT PT01922272T patent/PT1311272E/pt unknown
- 2001-03-05 DE DE60124730T patent/DE60124730T2/de not_active Expired - Lifetime
- 2001-07-06 US US09/899,028 patent/US20020035128A1/en not_active Abandoned
- 2001-09-04 US US09/947,087 patent/US6482838B2/en not_active Expired - Fee Related
- 2001-09-04 US US09/947,086 patent/US6458807B1/en not_active Expired - Lifetime
-
2002
- 2002-01-25 US US10/054,931 patent/US6576646B1/en not_active Expired - Fee Related
- 2002-09-03 US US10/232,406 patent/US6689795B2/en not_active Expired - Fee Related
-
2003
- 2003-12-11 US US10/732,349 patent/US7563808B2/en not_active Expired - Fee Related
-
2005
- 2005-07-15 US US11/181,855 patent/US20050250812A1/en not_active Abandoned
-
2007
- 2007-01-29 CY CY20071100121T patent/CY1107997T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2275670T3 (es) | 2007-06-16 |
| US6576646B1 (en) | 2003-06-10 |
| PT1311272E (pt) | 2007-02-28 |
| JP2003525903A (ja) | 2003-09-02 |
| EP2133078A1 (de) | 2009-12-16 |
| EP2130538A1 (de) | 2009-12-09 |
| EP2138177A1 (de) | 2009-12-30 |
| CY1107997T1 (el) | 2013-09-04 |
| EP1311272B1 (de) | 2006-11-22 |
| US20020035129A1 (en) | 2002-03-21 |
| EP1311272A1 (de) | 2003-05-21 |
| US6482838B2 (en) | 2002-11-19 |
| EP1311272A4 (de) | 2003-05-21 |
| US6689795B2 (en) | 2004-02-10 |
| US6458807B1 (en) | 2002-10-01 |
| DK1311272T3 (da) | 2007-02-26 |
| US20050250812A1 (en) | 2005-11-10 |
| WO2001066114A1 (en) | 2001-09-13 |
| AU2001249091A1 (en) | 2001-09-17 |
| US20020035128A1 (en) | 2002-03-21 |
| DE60124730T2 (de) | 2007-10-04 |
| US7563808B2 (en) | 2009-07-21 |
| DE60124730D1 (de) | 2007-01-04 |
| US20030040532A1 (en) | 2003-02-27 |
| EP2140868A1 (de) | 2010-01-06 |
| US20020040038A1 (en) | 2002-04-04 |
| US20040122051A1 (en) | 2004-06-24 |
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