ATE346592T1 - Pharmazeutische zubereitungen mit einem cortisol synthese inhibitor - Google Patents
Pharmazeutische zubereitungen mit einem cortisol synthese inhibitorInfo
- Publication number
- ATE346592T1 ATE346592T1 AT02751341T AT02751341T ATE346592T1 AT E346592 T1 ATE346592 T1 AT E346592T1 AT 02751341 T AT02751341 T AT 02751341T AT 02751341 T AT02751341 T AT 02751341T AT E346592 T1 ATE346592 T1 AT E346592T1
- Authority
- AT
- Austria
- Prior art keywords
- melting point
- lipid
- pharmaceutical preparations
- preparations containing
- synthesis inhibitor
- Prior art date
Links
- 229940126165 cortisol synthesis inhibitor Drugs 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 150000002632 lipids Chemical class 0.000 abstract 7
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 6
- 230000008018 melting Effects 0.000 abstract 4
- 238000002844 melting Methods 0.000 abstract 4
- XMAYWYJOQHXEEK-OZXSUGGESA-N (2R,4S)-ketoconazole Chemical compound C1CN(C(=O)C)CCN1C(C=C1)=CC=C1OC[C@@H]1O[C@@](CN2C=NC=C2)(C=2C(=CC(Cl)=CC=2)Cl)OC1 XMAYWYJOQHXEEK-OZXSUGGESA-N 0.000 abstract 2
- 229960004125 ketoconazole Drugs 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 208000001145 Metabolic Syndrome Diseases 0.000 abstract 1
- 201000000690 abdominal obesity-metabolic syndrome Diseases 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000007790 solid phase Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0118300.3A GB0118300D0 (en) | 2001-07-26 | 2001-07-26 | Formulations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE346592T1 true ATE346592T1 (de) | 2006-12-15 |
Family
ID=9919282
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02751341T ATE346592T1 (de) | 2001-07-26 | 2002-07-26 | Pharmazeutische zubereitungen mit einem cortisol synthese inhibitor |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20050013834A1 (de) |
| EP (1) | EP1414419B1 (de) |
| AT (1) | ATE346592T1 (de) |
| DE (1) | DE60216471T2 (de) |
| GB (1) | GB0118300D0 (de) |
| WO (1) | WO2003011258A1 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0001899D0 (sv) | 2000-05-22 | 2000-05-22 | Pharmacia & Upjohn Ab | New compounds |
| EA200400707A1 (ru) | 2001-11-22 | 2004-10-28 | Биовитрум Аб | Ингибиторы 11-бета-гидроксистероиддегидрогеназы типа 1 |
| US20040191207A1 (en) * | 2003-03-31 | 2004-09-30 | Lipari John M. | Alpha-hydroxy acid ester drug delivery compositions and methods of use |
| AU2006204334B2 (en) * | 2005-01-10 | 2012-02-23 | Cortendo Ab (Publ) | Methods and compositions for treating diabetes, metabolic syndrome and other conditions |
| CA2637000A1 (en) * | 2006-01-10 | 2007-07-19 | Diobex, Inc. | Methods and compositions for treating prostate cancer, benign prostatic hypertrophy, polycystic ovary syndrome and other conditions |
| WO2007121479A2 (en) * | 2006-04-18 | 2007-10-25 | Cortendo Invest, Ab | Methods and compositions for treating barth syndrome, cardiomyopathy, mitochondrial diseases and other conditions |
| AU2007303219A1 (en) * | 2006-10-02 | 2008-04-10 | Cortendo Ab (Publ) | Ketoconazole enantiomer in humans |
| CN101686994B (zh) | 2006-10-20 | 2013-05-01 | 陶氏环球技术公司 | 水溶性纤维素衍生物制备用于预防或治疗代谢综合征的药物等的用途 |
| AR082803A1 (es) * | 2010-09-01 | 2013-01-09 | Portola Pharm Inc | Metodos y formulaciones para el tratamiento de la trombosis con betrixaban y un inhibidor de la glicoproteina p |
| EP3049084A4 (de) * | 2013-09-25 | 2017-03-15 | Cortendo AB (publ) | Neuartige funktionalisierte 5-(phenoxymethyl)-1,3-dioxan-analoga mit cytochrom-p450-hemmung |
| EP3226845A1 (de) * | 2014-12-04 | 2017-10-11 | Capsugel Belgium NV | Multipartikuläre lipidformulierungen |
| WO2020074958A1 (en) | 2018-10-12 | 2020-04-16 | Strongbridge Dublin Limited | Levoketoconazole for treatment of congenital adrenal hyperplasia and primary aldosteronism |
| CN116919897A (zh) * | 2023-08-19 | 2023-10-24 | 四川大学华西医院 | 一种酮康唑纳米晶混悬液及其制备方法和应用 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4369172A (en) * | 1981-12-18 | 1983-01-18 | Forest Laboratories Inc. | Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose |
| US5468755A (en) * | 1988-05-10 | 1995-11-21 | The Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Therapeutic process for the treatment of the pathologies of Type II diabetes |
| BR9206593A (pt) * | 1991-10-04 | 1995-11-28 | Gs Biochem Ab | Partículas especialmente partículas coloidais processo de prepará-las a partir de uma fase cristalina líquida homogênea ou fase L3 composição farmacêutica e uso destas partículas |
| AU5955094A (en) * | 1992-12-22 | 1994-07-19 | Sepracor, Inc. | Methods and compositions of (-) ketoconazole for treating fungal yeast and dermatophyte infections |
| JP3081766B2 (ja) * | 1994-05-06 | 2000-08-28 | 東興薬品工業株式会社 | 角質貯留型抗真菌外用組成物 |
| US5958458A (en) * | 1994-06-15 | 1999-09-28 | Dumex-Alpharma A/S | Pharmaceutical multiple unit particulate formulation in the form of coated cores |
| WO1996004912A1 (en) * | 1994-08-09 | 1996-02-22 | Metabolic Syndrome I Gbg Ab | Use of ketoconazole and related substances in medicaments for treatment of type ii diabetes |
| KR100336090B1 (ko) * | 1998-06-27 | 2002-05-27 | 윤승원 | 오일, 지방산 또는 이들의 혼합물을 함유한 난용성 약물의 고형분산제제 |
| US6294192B1 (en) * | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
| US6267985B1 (en) * | 1999-06-30 | 2001-07-31 | Lipocine Inc. | Clear oil-containing pharmaceutical compositions |
| US6248363B1 (en) * | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
| GB9915625D0 (en) * | 1999-07-02 | 1999-09-01 | Cortendo Ab | Method |
| US6428809B1 (en) * | 1999-08-18 | 2002-08-06 | Microdose Technologies, Inc. | Metering and packaging of controlled release medication |
| GB0001449D0 (en) * | 2000-01-21 | 2000-03-08 | Cortendo Ab | Compositions |
-
2001
- 2001-07-26 GB GBGB0118300.3A patent/GB0118300D0/en not_active Ceased
-
2002
- 2002-07-26 US US10/484,783 patent/US20050013834A1/en not_active Abandoned
- 2002-07-26 EP EP02751341A patent/EP1414419B1/de not_active Expired - Lifetime
- 2002-07-26 AT AT02751341T patent/ATE346592T1/de not_active IP Right Cessation
- 2002-07-26 WO PCT/GB2002/003444 patent/WO2003011258A1/en not_active Ceased
- 2002-07-26 DE DE60216471T patent/DE60216471T2/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE60216471T2 (de) | 2007-03-29 |
| US20050013834A1 (en) | 2005-01-20 |
| EP1414419A1 (de) | 2004-05-06 |
| EP1414419B1 (de) | 2006-11-29 |
| GB0118300D0 (en) | 2001-09-19 |
| WO2003011258A1 (en) | 2003-02-13 |
| DE60216471D1 (de) | 2007-01-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE346592T1 (de) | Pharmazeutische zubereitungen mit einem cortisol synthese inhibitor | |
| CY1115707T1 (el) | Στερεα σταθεροποιημενα θεραπευτικα συστηματα ταχειας και/ή τροποποιημενης απελευθερωσης για τη χορηγηση απο του στοματος υγρων δραστικων ουσιων, εκδοχων ή τροφιμων | |
| GEP20043180B (en) | Polymorphous Crystal Forms of Celecoxib, Methods for Their Production and Pharmaceutical Composition Comprising the Same for Treatment or Prevention of Diseases Caused by Cyclooxygenase-2 | |
| HRP20020045A2 (en) | Oral liquid compositions | |
| PL372809A1 (en) | Substituted 1,3-diphenylprop-2-en-1-one derivatives and preparation and uses thereof | |
| BRPI0410219A (pt) | composições farmacêuticas de vareniclina | |
| MEP56908A (en) | Reconstitutable parenteral composition containing a cox-2 inhibitor | |
| TW200718418A (en) | Cannabinoid active pharmaceutical ingredient for improved dosage forms | |
| BRPI0108395B8 (pt) | derivados de pirrolopirimidinona, processos de preparação e uso | |
| ATE423556T1 (de) | Capsaicin-enthaltende missbrauchsichere pharmazeutische zusammensetzungen | |
| CY1106542T1 (el) | Μεθοδος για παρασκευη φαρμακευτικων συνθεσεων για χρηση με συνταγοποιησεις μαλακης ζελατινης | |
| ATE468126T1 (de) | Ingwer-extraktzubereitung | |
| AR055916A1 (es) | Derivados de dihidrobenzofurano, usos de los mismos en la preparacion de un medicamento y composicion farmaceutica | |
| BR0314898A (pt) | Compostos, composição cosmética, uso cosmético de uma composição, uso de um composto e composição farmacêutica | |
| EA200501268A1 (ru) | Ингибирующие вич 1,2,4-триазины | |
| MXPA05013645A (es) | Nuevos compuestos moduladores de los receptores de tipo ppar gama y su utilizacion en composiciones cosmeticas o farmaceuticas. | |
| HU9400430D0 (en) | New pyrazine derivatives, their preparation and pharmaceutical compositions containing them | |
| SE9904413D0 (sv) | Comminuted form | |
| SE0402925D0 (sv) | Novel Compounds | |
| DE69430070D1 (de) | Topische pharmazeutische zusammensetzungen die (s)-2-(4-isobutylphenyl) propionsaeure enthalten | |
| ATE424192T1 (de) | Stabile pharmazeutische zubereitungen mit 2-aza- bicyclo 3.3.0 -octan-3-carboxylsäure-derivaten | |
| DK1305057T3 (da) | Mikropartikelformig biomaterialesammensætning af hyaluronsyre til medicinsk anvendelse | |
| JP7086597B2 (ja) | 外用組成物 | |
| IL163608A (en) | Sulfonanilides are conserved in their amino / amino acids and derivatives, their process, their pharmaceutical preparations, and their conjugated antibodies and their use in the preparation of drugs for the treatment of culture disorders | |
| DE60222131D1 (de) | Neues alkaloidderivat und dieses enthaltende pharmazeutische zusammensetzung |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |