ATE346592T1 - Pharmazeutische zubereitungen mit einem cortisol synthese inhibitor - Google Patents

Pharmazeutische zubereitungen mit einem cortisol synthese inhibitor

Info

Publication number: ATE346592T1
Authority: AT; Austria
Prior art keywords: melting point; lipid; pharmaceutical preparations; preparations containing; synthesis inhibitor
Prior art date: 2001-07-26

Application number

AT02751341T

Other languages

English (en)

Inventor

Barbro Helena Ljusberg

Susanne Veronica Hylen

Asa Helen Fyge

Original Assignee

Cortendo Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-07-26

Filing date

2002-07-26

Publication date

2006-12-15

2002-07-26 Application filed by Cortendo Ab filed Critical Cortendo Ab

2006-12-15 Application granted granted Critical

2006-12-15 Publication of ATE346592T1 publication Critical patent/ATE346592T1/de

Links

229940126165 cortisol synthesis inhibitor Drugs 0.000 title 1
239000000825 pharmaceutical preparation Substances 0.000 title 1
150000002632 lipids Chemical class 0.000 abstract 7
239000000546 pharmaceutical excipient Substances 0.000 abstract 6
230000008018 melting Effects 0.000 abstract 4
238000002844 melting Methods 0.000 abstract 4
XMAYWYJOQHXEEK-OZXSUGGESA-N (2R,4S)-ketoconazole Chemical compound C1CN(C(=O)C)CCN1C(C=C1)=CC=C1OC[C@@H]1O[C@@](CN2C=NC=C2)(C=2C(=CC(Cl)=CC=2)Cl)OC1 XMAYWYJOQHXEEK-OZXSUGGESA-N 0.000 abstract 2
229960004125 ketoconazole Drugs 0.000 abstract 2
239000000203 mixture Substances 0.000 abstract 2
239000008194 pharmaceutical composition Substances 0.000 abstract 2
208000001145 Metabolic Syndrome Diseases 0.000 abstract 1
201000000690 abdominal obesity-metabolic syndrome Diseases 0.000 abstract 1
238000009472 formulation Methods 0.000 abstract 1
238000010438 heat treatment Methods 0.000 abstract 1
239000007788 liquid Substances 0.000 abstract 1
239000007790 solid phase Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds

Landscapes

Health & Medical Sciences (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Physiology (AREA)
Nutrition Science (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT02751341T 2001-07-26 2002-07-26 Pharmazeutische zubereitungen mit einem cortisol synthese inhibitor ATE346592T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB0118300.3A GB0118300D0 (en)	2001-07-26	2001-07-26	Formulations

Publications (1)

Publication Number	Publication Date
ATE346592T1 true ATE346592T1 (de)	2006-12-15

Family

ID=9919282

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT02751341T ATE346592T1 (de)	2001-07-26	2002-07-26	Pharmazeutische zubereitungen mit einem cortisol synthese inhibitor

Country Status (6)

Country	Link
US (1)	US20050013834A1 (de)
EP (1)	EP1414419B1 (de)
AT (1)	ATE346592T1 (de)
DE (1)	DE60216471T2 (de)
GB (1)	GB0118300D0 (de)
WO (1)	WO2003011258A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE0001899D0 (sv)	2000-05-22	2000-05-22	Pharmacia & Upjohn Ab	New compounds
RS44304A (sr)	2001-11-22	2007-06-04	Biovitrum Ab.,	Inhibitori 11-beta- hidroksistereoidne dehidrogenaze tipa 1
US20040191207A1 (en) *	2003-03-31	2004-09-30	Lipari John M.	Alpha-hydroxy acid ester drug delivery compositions and methods of use
ES2377526T3 (es) *	2005-01-10	2012-03-28	Cortendo Ab (Publ)	2S,4R ketoconazol para el tratamiento de la diabetes, el síndrome metabólico y otras afecciones
WO2007081980A2 (en) *	2006-01-10	2007-07-19	Diobex, Inc.	Methods and compositions for treating prostate cancer
WO2007121479A2 (en) *	2006-04-18	2007-10-25	Cortendo Invest, Ab	Methods and compositions for treating barth syndrome, cardiomyopathy, mitochondrial diseases and other conditions
JP2010505866A (ja) *	2006-10-02	2010-02-25	コルテンド・インヴェスト・アクチボラゲット	ヒトにおけるケトコナゾールエナンチオマー
EP2079476B1 (de) *	2006-10-20	2014-05-21	Dow Global Technologies LLC	Verwendung hydroxypropylmethylcellulose zur vorbeugung oder behandlung des stoffwechselsyndroms
AR082803A1 (es) *	2010-09-01	2013-01-09	Portola Pharm Inc	Metodos y formulaciones para el tratamiento de la trombosis con betrixaban y un inhibidor de la glicoproteina p
JP2016536273A (ja) *	2013-09-25	2016-11-24	コーテンドーエービー（ピーユービーエル）ＣｏｒｔｅｎｄｏＡｂ（Ｐｕｂｌ）	チトクロムｐ４５０阻害を示す新規な官能化５−（フェノキシメチル）−１，３−ジオキサンアナログ
US11324699B2 (en) *	2014-12-04	2022-05-10	Capsugel Belgium Nv	Lipid multiparticulate formulations
EP3863634A1 (de)	2018-10-12	2021-08-18	Strongbridge Dublin Limited	Levoketoconazol zur behandlung von kongenitaler adrenalhyperplasie und primärem aldosteronismus
CN116919897A (zh) *	2023-08-19	2023-10-24	四川大学华西医院	一种酮康唑纳米晶混悬液及其制备方法和应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4369172A (en) *	1981-12-18	1983-01-18	Forest Laboratories Inc.	Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose
US5468755A (en) *	1988-05-10	1995-11-21	The Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College	Therapeutic process for the treatment of the pathologies of Type II diabetes
EP0643620B1 (de) *	1991-10-04	1999-07-21	Gs Development Ab	Teilchen, methode zur herstellung der teilchen und deren verwendung
WO1994014447A1 (en) *	1992-12-22	1994-07-07	Sepracor, Inc.	Methods and compositions of (-) ketoconazole for treating fungal yeast and dermatophyte infections
JP3081766B2 (ja) *	1994-05-06	2000-08-28	東興薬品工業株式会社	角質貯留型抗真菌外用組成物
US5958458A (en) *	1994-06-15	1999-09-28	Dumex-Alpharma A/S	Pharmaceutical multiple unit particulate formulation in the form of coated cores
PT779810E (pt) *	1994-08-09	2003-11-28	Cortendo Ab	Utilizacao de cetoconazole e substancias relacionadas em medicamentos para o tratamento da diabetes tipo ii
KR100336090B1 (ko) *	1998-06-27	2002-05-27	윤승원	오일, 지방산 또는 이들의 혼합물을 함유한 난용성 약물의 고형분산제제
US6294192B1 (en) *	1999-02-26	2001-09-25	Lipocine, Inc.	Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents
US6248363B1 (en) *	1999-11-23	2001-06-19	Lipocine, Inc.	Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
US6267985B1 (en) *	1999-06-30	2001-07-31	Lipocine Inc.	Clear oil-containing pharmaceutical compositions
GB9915625D0 (en) *	1999-07-02	1999-09-01	Cortendo Ab	Method
US6428809B1 (en) *	1999-08-18	2002-08-06	Microdose Technologies, Inc.	Metering and packaging of controlled release medication
GB0001449D0 (en) *	2000-01-21	2000-03-08	Cortendo Ab	Compositions

2001
- 2001-07-26 GB GBGB0118300.3A patent/GB0118300D0/en not_active Ceased
2002
- 2002-07-26 WO PCT/GB2002/003444 patent/WO2003011258A1/en not_active Ceased
- 2002-07-26 US US10/484,783 patent/US20050013834A1/en not_active Abandoned
- 2002-07-26 AT AT02751341T patent/ATE346592T1/de not_active IP Right Cessation
- 2002-07-26 DE DE60216471T patent/DE60216471T2/de not_active Expired - Lifetime
- 2002-07-26 EP EP02751341A patent/EP1414419B1/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
WO2003011258A1 (en)	2003-02-13
EP1414419A1 (de)	2004-05-06
DE60216471T2 (de)	2007-03-29
EP1414419B1 (de)	2006-11-29
GB0118300D0 (en)	2001-09-19
US20050013834A1 (en)	2005-01-20
DE60216471D1 (de)	2007-01-11

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Legal Events

Date	Code	Title	Description
2007-05-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties