ATE348148T1 - Leberstammzellen - Google Patents
LeberstammzellenInfo
- Publication number
- ATE348148T1 ATE348148T1 AT99935488T AT99935488T ATE348148T1 AT E348148 T1 ATE348148 T1 AT E348148T1 AT 99935488 T AT99935488 T AT 99935488T AT 99935488 T AT99935488 T AT 99935488T AT E348148 T1 ATE348148 T1 AT E348148T1
- Authority
- AT
- Austria
- Prior art keywords
- stem cells
- liver stem
- cells
- stem cell
- cell
- Prior art date
Links
- 210000000130 stem cell Anatomy 0.000 title abstract 3
- 210000004185 liver Anatomy 0.000 title abstract 2
- 210000004027 cell Anatomy 0.000 abstract 4
- 210000003494 hepatocyte Anatomy 0.000 abstract 1
- 210000005228 liver tissue Anatomy 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000002054 transplantation Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/067—Hepatocytes
- C12N5/0672—Stem cells; Progenitor cells; Precursor cells; Oval cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Developmental Biology & Embryology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cell Biology (AREA)
- Public Health (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/113,774 US6129911A (en) | 1998-07-10 | 1998-07-10 | Liver stem cell |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE348148T1 true ATE348148T1 (de) | 2007-01-15 |
Family
ID=22351445
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99935488T ATE348148T1 (de) | 1998-07-10 | 1999-07-08 | Leberstammzellen |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6129911A (de) |
| EP (1) | EP1097193B1 (de) |
| JP (1) | JP4610083B2 (de) |
| AT (1) | ATE348148T1 (de) |
| AU (1) | AU5095699A (de) |
| CA (1) | CA2336958A1 (de) |
| DE (1) | DE69934407T2 (de) |
| DK (1) | DK1097193T3 (de) |
| WO (1) | WO2000003001A1 (de) |
Families Citing this family (73)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6872389B1 (en) * | 1999-07-08 | 2005-03-29 | Rhode Island Hospital | Liver stem cell |
| US7456017B2 (en) * | 1999-10-01 | 2008-11-25 | University Of North Carolina At Chapel Hill | Processes for clonal growth of hepatic progenitor cells |
| US20020187133A1 (en) * | 1999-10-01 | 2002-12-12 | Hiroshi Kubota | Methods of isolating bipotent hepatic progenitor cells |
| IL150819A0 (en) * | 2000-01-19 | 2003-02-12 | Univ North Carolina | Liver tissue source |
| AU2001253425A1 (en) * | 2000-04-13 | 2001-10-30 | Board Of Regents, The University Of Texas System | Treatment of disorders by implanting stem cells and/or progeny thereof into gastrointestinal organs |
| US6458589B1 (en) | 2000-04-27 | 2002-10-01 | Geron Corporation | Hepatocyte lineage cells derived from pluripotent stem cells |
| US7256042B2 (en) | 2000-04-27 | 2007-08-14 | Geron Corporation | Process for making hepatocytes from pluripotent stem cells |
| US7282366B2 (en) | 2000-04-27 | 2007-10-16 | Geron Corporation | Hepatocytes for therapy and drug screening made from embryonic stem cells |
| US7473555B2 (en) | 2000-04-27 | 2009-01-06 | Geron Corporation | Protocols for making hepatocytes from embryonic stem cells |
| EP1290444B1 (de) | 2000-06-14 | 2009-10-07 | Vistagen, Inc. | Toxizitätstypisierung unter verwendung von leberstammzellen |
| CN1258589C (zh) * | 2000-10-03 | 2006-06-07 | 北卡罗来纳大学 | 分离双能肝祖细胞的方法 |
| US7838292B1 (en) | 2001-03-29 | 2010-11-23 | University Of Louisville Research Foundation, Inc. | Methods for obtaining adult human olfactory progenitor cells |
| ES2292772T3 (es) * | 2001-06-22 | 2008-03-16 | Stemcells, Inc. | Celulas de injerto de higado, analisis, y sus usos. |
| US20050064587A1 (en) * | 2001-09-07 | 2005-03-24 | Lawrence Rosenberg | Pancreatic small cells and uses thereof |
| CA2461290C (en) | 2001-09-24 | 2014-11-25 | Sangamo Biosciences, Inc. | Modulation of stem cells using zinc finger proteins |
| CA2479510C (en) * | 2002-03-15 | 2019-10-29 | University Of North Carolina At Chapel Hill | Primitive and proximal hepatic stem cells |
| EP1496110B1 (de) * | 2002-03-25 | 2012-05-09 | Hiroshima Industrial Promotion Organization | Verfahren zur vermehrung menschlicher hepatozyten und verfahren zur gewinnung menschlicher hepatozyten |
| US20040042997A1 (en) * | 2002-09-03 | 2004-03-04 | Donnie Rudd | Method of regenerating human tissue |
| US20040076620A1 (en) * | 2002-09-03 | 2004-04-22 | Donnie Rudd | Method of repairing primate mammalian tissue |
| US20040043009A1 (en) * | 2002-09-03 | 2004-03-04 | Donnie Rudd | Method of repairing primate mammalian tissue |
| US20040076605A1 (en) * | 2002-09-03 | 2004-04-22 | Donnie Rudd | Method of regenerating human tissue |
| US20040242568A1 (en) | 2003-03-25 | 2004-12-02 | Syrrx, Inc. | Dipeptidyl peptidase inhibitors |
| WO2004103993A1 (en) | 2003-05-14 | 2004-12-02 | Syrrx, Inc. | Dipeptidyl peptidase inhibitors |
| EP1506967B1 (de) | 2003-08-13 | 2007-11-21 | Takeda Pharmaceutical Company Limited | Dipeptidyl Peptidase Inhibitoren. |
| US7169926B1 (en) | 2003-08-13 | 2007-01-30 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
| US7678909B1 (en) | 2003-08-13 | 2010-03-16 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
| BR0318490A (pt) | 2003-09-02 | 2006-09-12 | Regenetech Inc | método para reparar tecido de mamìfero primata e para reconstituir células de mamìfero primata, e, composição de célula sangüìnea humana ex vivo |
| EP1699777B1 (de) | 2003-09-08 | 2012-12-12 | Takeda Pharmaceutical Company Limited | Dipeptidylpeptidase-hemmer |
| US7732446B1 (en) | 2004-03-11 | 2010-06-08 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
| MXPA06010571A (es) | 2004-03-15 | 2007-02-16 | Takeda Pharmaceutical | Inhibidores de dipeptidil peptidasa. |
| US7687638B2 (en) | 2004-06-04 | 2010-03-30 | Takeda San Diego, Inc. | Dipeptidyl peptidase inhibitors |
| KR100563297B1 (ko) * | 2004-06-16 | 2006-03-27 | 시 명 김 | 골프공 이송장치 |
| US7456019B2 (en) | 2004-06-30 | 2008-11-25 | Regenetech, Inc. | Three-dimensional cell to tissue development process |
| WO2006019965A2 (en) | 2004-07-16 | 2006-02-23 | Takeda San Diego, Inc. | Dipeptidyl peptidase inhibitors |
| JP4854509B2 (ja) * | 2004-08-20 | 2012-01-18 | 積水メディカル株式会社 | 薬物のヒトにおける肝代謝及び肝機能を予測する方法 |
| EP1828192B1 (de) | 2004-12-21 | 2014-12-03 | Takeda Pharmaceutical Company Limited | Dipeptidylpeptidasehemmer |
| WO2006126219A1 (en) | 2005-05-26 | 2006-11-30 | Fresenius Medical Care Deutschland G.M.B.H. | Liver progenitor cells |
| ME02005B (me) | 2005-09-14 | 2012-08-31 | Takeda Pharmaceuticals Co | Inhibitori dipeptidil peptidaze za lečenje dijabetesa |
| WO2007033265A1 (en) * | 2005-09-14 | 2007-03-22 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors for treating diabetis |
| CN101360723A (zh) | 2005-09-16 | 2009-02-04 | 武田药品工业株式会社 | 制备嘧啶二酮衍生物的方法 |
| US20080009442A1 (en) | 2005-12-06 | 2008-01-10 | Institute For Human Genetics And Biochemistry | Therapeutic use for alpha1 proteinase inhibitor in hematopoiesis |
| NZ594639A (en) | 2006-03-07 | 2013-04-26 | Geeta Shroff | Compositions comprising human embryonic stem cells and their derivatives, methods of use, and methods of preparation |
| WO2007112347A1 (en) | 2006-03-28 | 2007-10-04 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
| WO2007143117A2 (en) * | 2006-06-02 | 2007-12-13 | Geron Corporation | Differentiation of primate pluripotent cells to hepatocyte-lineage cells |
| US20100068187A1 (en) * | 2006-08-31 | 2010-03-18 | Roisen Fred J | Transcription factors for differentiation of adult human olfactory progenitor cells |
| US8324383B2 (en) | 2006-09-13 | 2012-12-04 | Takeda Pharmaceutical Company Limited | Methods of making polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile |
| TW200838536A (en) | 2006-11-29 | 2008-10-01 | Takeda Pharmaceutical | Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor |
| US8093236B2 (en) | 2007-03-13 | 2012-01-10 | Takeda Pharmaceuticals Company Limited | Weekly administration of dipeptidyl peptidase inhibitors |
| US8574567B2 (en) * | 2007-05-03 | 2013-11-05 | The Brigham And Women's Hospital, Inc. | Multipotent stem cells and uses thereof |
| WO2008137115A1 (en) | 2007-05-03 | 2008-11-13 | The Brigham And Women's Hospital, Inc. | Multipotent stem cells and uses thereof |
| US20100144140A1 (en) * | 2008-12-10 | 2010-06-10 | Novellus Systems, Inc. | Methods for depositing tungsten films having low resistivity for gapfill applications |
| US20100329986A1 (en) * | 2009-01-06 | 2010-12-30 | Greenbaum Linda E | Adult Hepatic Progenitor Cells and Methods of Use Thereof |
| ES2699630T3 (es) | 2010-04-23 | 2019-02-12 | Cold Spring Harbor Laboratory | Novedosos ARNhc diseñados estructuralmente |
| AU2015205872B2 (en) * | 2010-05-07 | 2017-07-06 | University Of North Carolina At Chapel Hill | Method of engrafting cells from solid tissues |
| BR112012028265B1 (pt) * | 2010-05-07 | 2021-09-21 | The University Of North Carolina At Chapel Hill | Usos de células hepáticas e método de criopreservação de células |
| WO2012048275A2 (en) | 2010-10-08 | 2012-04-12 | Caridianbct, Inc. | Configurable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system |
| EA034878B1 (ru) * | 2013-08-28 | 2020-04-01 | Прометера Байосайенсиз С.А./Н.В. | Способ получения клеток-предшественников зрелой печени |
| CN105793411B (zh) | 2013-11-16 | 2018-04-17 | 泰尔茂比司特公司 | 生物反应器中的细胞扩增 |
| BR112016013623B1 (pt) | 2013-12-16 | 2023-03-21 | Fresenius Medical Care Deutschland Gmbh | Método de preparação de uma estrutura de célula esferoide semelhante à ilhota pancreática cultivada artificialmente, e uso de uma estrutura de célula esferoide |
| JP6783143B2 (ja) | 2014-03-25 | 2020-11-11 | テルモ ビーシーティー、インコーポレーテッド | 培地の受動的補充 |
| WO2016030525A1 (en) | 2014-08-28 | 2016-03-03 | Promethera Biosciences S.A./N.V. | Method for producing adult liver progenitor cells |
| US20160090569A1 (en) | 2014-09-26 | 2016-03-31 | Terumo Bct, Inc. | Scheduled Feed |
| WO2016179481A1 (en) | 2015-05-07 | 2016-11-10 | Cardelli James Allen | Cancer treatment via repositioned tricyclic anti-depressant-like drugs as anti-cancer agents and new combinations of such drugs |
| WO2017004592A1 (en) | 2015-07-02 | 2017-01-05 | Terumo Bct, Inc. | Cell growth with mechanical stimuli |
| US11965175B2 (en) | 2016-05-25 | 2024-04-23 | Terumo Bct, Inc. | Cell expansion |
| US11104874B2 (en) | 2016-06-07 | 2021-08-31 | Terumo Bct, Inc. | Coating a bioreactor |
| US11685883B2 (en) | 2016-06-07 | 2023-06-27 | Terumo Bct, Inc. | Methods and systems for coating a cell growth surface |
| US12234441B2 (en) | 2017-03-31 | 2025-02-25 | Terumo Bct, Inc. | Cell expansion |
| US11624046B2 (en) | 2017-03-31 | 2023-04-11 | Terumo Bct, Inc. | Cell expansion |
| US11629332B2 (en) | 2017-03-31 | 2023-04-18 | Terumo Bct, Inc. | Cell expansion |
| EP4314244B1 (de) | 2021-03-23 | 2025-07-23 | Terumo BCT, Inc. | Zellerfassung und -erweiterung |
| US12152699B2 (en) | 2022-02-28 | 2024-11-26 | Terumo Bct, Inc. | Multiple-tube pinch valve assembly |
| USD1099116S1 (en) | 2022-09-01 | 2025-10-21 | Terumo Bct, Inc. | Display screen or portion thereof with a graphical user interface for displaying cell culture process steps and measurements of an associated bioreactor device |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5367057A (en) * | 1991-04-02 | 1994-11-22 | The Trustees Of Princeton University | Tyrosine kinase receptor flk-2 and fragments thereof |
| EP0597964A4 (de) * | 1991-08-07 | 1994-11-30 | Einstein Coll Med | Proliferation von vorläufern von hepatocyten. |
| US5460964A (en) * | 1992-04-03 | 1995-10-24 | Regents Of The University Of Minnesota | Method for culturing hematopoietic cells |
| WO1994008598A1 (en) * | 1992-10-09 | 1994-04-28 | Advanced Tissue Sciences, Inc. | Liver reserve cells |
| US5532156A (en) * | 1993-10-08 | 1996-07-02 | The United States Of America As Represented By The Secretary Of Agriculture | Hepatocyte cell line derived from the epiblast of pig blastocysts |
| US5861313A (en) * | 1995-06-07 | 1999-01-19 | Ontogeny, Inc. | Method of isolating bile duct progenitor cells |
-
1998
- 1998-07-10 US US09/113,774 patent/US6129911A/en not_active Expired - Lifetime
-
1999
- 1999-07-08 AU AU50956/99A patent/AU5095699A/en not_active Abandoned
- 1999-07-08 DK DK99935488T patent/DK1097193T3/da active
- 1999-07-08 EP EP99935488A patent/EP1097193B1/de not_active Expired - Lifetime
- 1999-07-08 CA CA002336958A patent/CA2336958A1/en not_active Abandoned
- 1999-07-08 DE DE69934407T patent/DE69934407T2/de not_active Expired - Lifetime
- 1999-07-08 AT AT99935488T patent/ATE348148T1/de active
- 1999-07-08 WO PCT/US1999/015625 patent/WO2000003001A1/en not_active Ceased
- 1999-07-08 JP JP2000559223A patent/JP4610083B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2002520015A (ja) | 2002-07-09 |
| DK1097193T3 (da) | 2007-04-23 |
| DE69934407T2 (de) | 2007-09-27 |
| EP1097193A1 (de) | 2001-05-09 |
| CA2336958A1 (en) | 2000-01-20 |
| WO2000003001A1 (en) | 2000-01-20 |
| US6129911A (en) | 2000-10-10 |
| JP4610083B2 (ja) | 2011-01-12 |
| AU5095699A (en) | 2000-02-01 |
| DE69934407D1 (de) | 2007-01-25 |
| EP1097193B1 (de) | 2006-12-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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